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Items: 42

1.

Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.

Washburn DG, Hoang TH, Frazee JS, Johnson L, Hammond M, Manns S, Madauss KP, Williams SP, Duraiswami C, Tran TB, Stewart EL, Grygielko ET, Glace LE, Trizna W, Nagilla R, Bray JD, Thompson SK.

Bioorg Med Chem Lett. 2009 Aug 15;19(16):4664-8. doi: 10.1016/j.bmcl.2009.06.081. Epub 2009 Jun 25.

PMID:
19616429
2.

Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists.

Thompson SK, Washburn DG, Frazee JS, Madauss KP, Hoang TH, Lapinski L, Grygielko ET, Glace LE, Trizna W, Williams SP, Duraiswami C, Bray JD, Laping NJ.

Bioorg Med Chem Lett. 2009 Aug 15;19(16):4777-80. doi: 10.1016/j.bmcl.2009.06.055. Epub 2009 Jun 17.

PMID:
19595590
3.

Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.

Hammond M, Washburn DG, Hoang HT, Manns S, Frazee JS, Nakamura H, Patterson JR, Trizna W, Wu C, Azzarano LM, Nagilla R, Nord M, Trejo R, Head MS, Zhao B, Smallwood AM, Hightower K, Laping NJ, Schnackenberg CG, Thompson SK.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4441-5. doi: 10.1016/j.bmcl.2009.05.051. Epub 2009 May 18.

PMID:
19497745
4.

Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists.

Hammond M, Patterson JR, Manns S, Hoang TH, Washburn DG, Trizna W, Glace L, Grygielko ET, Nagilla R, Nord M, Fries HE, Minick DJ, Laping NJ, Bray JD, Thompson SK.

Bioorg Med Chem Lett. 2009 May 15;19(10):2637-41. doi: 10.1016/j.bmcl.2009.03.146. Epub 2009 Apr 5.

PMID:
19376703
5.

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

Sherk AB, Frigo DE, Schnackenberg CG, Bray JD, Laping NJ, Trizna W, Hammond M, Patterson JR, Thompson SK, Kazmin D, Norris JD, McDonnell DP.

Cancer Res. 2008 Sep 15;68(18):7475-83. doi: 10.1158/0008-5472.CAN-08-1047.

6.

Transport of [3H]losartan across isolated perfused rabbit proximal tubule.

Edwards RM, Stack EJ, Trizna W.

J Pharmacol Exp Ther. 1999 Jul;290(1):38-42.

7.

Interaction of L-arginine analogs with L-arginine uptake in rat renal brush border membrane vesicles.

Edwards RM, Stack EJ, Trizna W.

J Pharmacol Exp Ther. 1998 Jun;285(3):1019-22.

8.

[125I]endothelin-1 binding to renal brush border and basolateral membranes.

Edwards RM, Trizna W, Stack EJ.

Eur J Pharmacol. 1998 Mar 19;345(2):229-32.

PMID:
9600642
9.

alpha-Ketoglutarate transport in rat renal brush-border and basolateral membrane vesicles.

Edwards RM, Stack E, Trizna W.

J Pharmacol Exp Ther. 1997 Jun;281(3):1059-64.

10.

Adrenomedullin: a new peptide involved in cardiorenal homeostasis?

Edwards RM, Trizna W, Aiyar N.

Exp Nephrol. 1997 Jan-Feb;5(1):18-22. Review.

PMID:
9052844
11.

Effect of adrenomedullin on cAMP levels along the rat nephron: comparison with CGRP.

Edwards RM, Trizna W, Stack E, Aiyar N.

Am J Physiol. 1996 Oct;271(4 Pt 2):F895-9.

PMID:
8898020
12.

Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes.

Edwards RM, Trizna W, Stack EJ, Weinstock J.

J Pharmacol Exp Ther. 1996 Jan;276(1):125-9.

PMID:
8558420
13.

SB 203220: a novel angiotensin II receptor antagonist and renoprotective agent.

Brooks DP, Contino LC, Short BG, Gowan C, Trizna W, Edwards RM.

J Pharmacol Exp Ther. 1995 Sep;274(3):1222-7.

PMID:
7562492
14.

Characterization of 125I-endothelin-1 binding to rat and rabbit renal microvasculature.

Edwards RM, Trizna W.

J Pharmacol Exp Ther. 1995 Sep;274(3):1084-9.

PMID:
7562473
15.

Modulation of glomerular arteriolar tone by nitric oxide synthase inhibitors.

Edwards RM, Trizna W.

J Am Soc Nephrol. 1993 Nov;4(5):1127-32.

16.

Calcitonin gene-related peptide stimulates adenylate cyclase and relaxes intracerebral arterioles.

Edwards RM, Stack EJ, Trizna W.

J Pharmacol Exp Ther. 1991 Jun;257(3):1020-4.

PMID:
1710661
17.

Platelet-activating factor (PAF) has no direct effect on rat intracerebral arterioles in vitro.

Edwards RM, Trizna W, Feuerstein G.

J Lipid Mediat. 1991 Mar-Apr;3(2):161-5.

PMID:
1797151
18.
19.

Renal microvascular effects of endothelin.

Edwards RM, Trizna W, Ohlstein EH.

Am J Physiol. 1990 Aug;259(2 Pt 2):F217-21.

PMID:
2201203
20.

Effect of enalapril or the thromboxane receptor antagonist, daltroban, in rats with subtotal renal ablation.

Brooks DP, Contino LC, Trizna W, Edwards RM, Ohlstein EH, Solleveld HA.

J Pharmacol Exp Ther. 1990 Apr;253(1):119-23.

PMID:
2139468
21.

Response of isolated intracerebral arterioles to endothelins.

Edwards R, Trizna W.

Pharmacology. 1990;41(3):149-52.

PMID:
2277808
22.

Calcitonin gene-related peptide: effects on renal arteriolar tone and tubular cAMP levels.

Edwards RM, Trizna W.

Am J Physiol. 1990 Jan;258(1 Pt 2):F121-5.

PMID:
2154123
23.

Renal microvascular effects of vasopressin and vasopressin antagonists.

Edwards RM, Trizna W, Kinter LB.

Am J Physiol. 1989 Feb;256(2 Pt 2):F274-8.

PMID:
2916660
24.

Characterization of alpha-adrenoceptors on isolated rabbit renal arterioles.

Edwards RM, Trizna W.

Am J Physiol. 1988 Feb;254(2 Pt 2):F178-83.

PMID:
2830789
25.

Hypertrophy of basolateral Na-K pump activity in the proximal tubule of the remnant kidney.

Salehmoghaddam S, Bradley T, Mikhail N, Badie-Dezfooly B, Nord EP, Trizna W, Kheyfets R, Fine LG.

Lab Invest. 1985 Oct;53(4):443-52.

PMID:
2413277
26.

pH gradient-dependent increased Na+-H+ antiport capacity of the rabbit remnant kidney.

Nord EP, Hafezi A, Kaunitz JD, Trizna W, Fine LG.

Am J Physiol. 1985 Jul;249(1 Pt 2):F90-8.

PMID:
2409819
27.

Transport and metabolism of glucose by renal proximal tubular cells in primary culture.

Sakhrani LM, Badie-Dezfooly B, Trizna W, Mikhail N, Lowe AG, Taub M, Fine LG.

Am J Physiol. 1984 Jun;246(6 Pt 2):F757-64.

PMID:
6742127
28.

Changes in glomerular and cortical tubular cAMP metabolism in kidneys from rats with unilateral ureteral obstruction.

Schlondorff D, Satriano JA, Trizna W, Weber H.

Ren Physiol. 1983 Jul-Aug;6(4):171-85.

PMID:
6310710
29.

Functional profile of the isolated uremic nephron: intrinsic adaptation of phosphate transport in the rabbit proximal tubule.

Yanagawa N, Nissenson RA, Edwards B, Yeung P, Trizna W, Fine LG.

Kidney Int. 1983 May;23(5):674-83.

30.
31.

Regulation of phosphate excretion by the diseased kidney: the intrinsic proximal tubular adaptation.

Yanagawa N, Yeung P, Trizna W, Fine LG.

Adv Exp Med Biol. 1982;151:177-83. No abstract available.

PMID:
6295089
32.

Functional profile of the isolated uremic nephron. Evidence of proximal tubular "memory" in experimental renal disease.

Trizna W, Yanagawa N, Bar-Khayim Y, Houston B, Fine LG.

J Clin Invest. 1981 Sep;68(3):760-7.

33.

Effects of vasopressin on the isolated perfused human collecting tubule.

Yanagawa N, Trizna W, Bar-Khayim Y, Fine LG.

Kidney Int. 1981 May;19(5):705-9.

34.

In vivo "culture" of a transporting renal epithelial monolayer.

Bar-Khayim Y, Cohen AH, Houston B, Trizna W, Fine LG.

Kidney Int. 1981 Mar;19(3):465-70. No abstract available.

35.

Functional profile of the isolated uremic nephron: potassium adaptation in the rabbit cortical collecting tubule.

Fine LG, Yanagawa N, Schultze RG, Tuck M, Trizna W.

J Clin Invest. 1979 Oct;64(4):1033-43.

36.

Increases of guanosine 3',5'-monophosphate-related enzymes in kidneys of developing rats.

Schlondorff D, Trizna W.

Pediatr Res. 1978 Aug;12(8):882-5.

PMID:
28509
39.

Glutathione-S-transferase activity in the rabbit nephron: segmental localization in isolated tubules and formation of thiol adducts of ethacrynic acid.

Fine LG, Goldstein EJ, Trizna W, Rozmaryn L, Arias IM.

Proc Soc Exp Biol Med. 1978 Feb;157(2):189-93. No abstract available.

PMID:
622382
40.

Vasopressin responsiveness of renal adenylate cyclase in newborn rats and rabbits.

Schlondorff D, Weber H, Trizna W, Fine LG.

Am J Physiol. 1978 Jan;234(1):F16-21.

PMID:
623260
41.

Effect of testosterone on compensatory renal hypertrophy in the rat.

Schlondorff D, Trizna W, De Rosis E, Korth-Schutz S.

Endocrinology. 1977 Dec;101(6):1670-5.

PMID:
590183
42.

Influence of prostaglandins on sodium transport of isolated medullary nephron segments.

Fine LG, Trizna W.

Am J Physiol. 1977 Apr;232(4):F383-90.

PMID:
851196

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