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Items: 21

1.

Natural allosteric modulators and their biological targets: molecular signatures and mechanisms.

Bruder M, Polo G, Trivella DBB.

Nat Prod Rep. 2020 Feb 12. doi: 10.1039/c9np00064j. [Epub ahead of print] Review.

PMID:
32048675
2.

Water-Soluble Glutamic Acid Derivatives Produced in Culture by Penicillium solitum IS1-A from King George Island, Maritime Antarctica.

Rodríguez JPG, Bernardi DI, Gubiani JR, Magalhães de Oliveira J, Morais-Urano RP, Bertonha AF, Bandeira KF, Bulla JIQ, Sette LD, Ferreira AG, Batista JM Jr, Silva TS, Santos RAD, Martins CHG, Lira SP, Cunha MGD, Trivella DBB, Grazzia N, Gomes NES, Gadelha F, Miguel DC, Cauz ACG, Brocchi M, Berlinck RGS.

J Nat Prod. 2020 Jan 24;83(1):55-65. doi: 10.1021/acs.jnatprod.9b00635. Epub 2020 Jan 2.

PMID:
31895573
3.

Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth.

de Souza RTMP, Freire VF, Gubiani JR, Ferreira RO, Trivella DBB, Moraes FC, Paradas WC, Salgado LT, Pereira RC, Amado Filho GM, Ferreira AG, Williams DE, Andersen RJ, Molinski TF, Berlinck RGS.

J Nat Prod. 2018 Oct 26;81(10):2296-2300. doi: 10.1021/acs.jnatprod.8b00533. Epub 2018 Oct 3.

PMID:
30281303
4.

A non-functional galanin receptor-2 in a multiple sclerosis patient.

Garcia-Rosa S, Trivella DB, Marques VD, Serafim RB, Pereira JG, Lorenzi JC, Molfetta GA, Christo PP, Olival GS, Marchitto VB, Brum DG, Sabedot TS, Noushmehr H, Farias AS, Santos LM, Nogueira-Machado JA, Souza JE, Romano CM, Conde RM, Santos AC, Guerreiro CT, Schreuder WH, Gleber-Netto FO, Amorim M, Valieris R, Silva ITD, Silva WA Jr, Nunes DN, Oliveira PS, Valente V, Arruda MA, Hill SJ, Barreira AA, Dias-Neto E.

Pharmacogenomics J. 2019 Feb;19(1):72-82. doi: 10.1038/s41397-018-0032-6. Epub 2018 Aug 22.

PMID:
30131588
5.

Formal Total Synthesis of Actinoranone: Synthesis Approaches and Cytotoxic Studies.

Novaes LFT, Gonçalves KA, Trivella DBB, Pastre JC.

J Org Chem. 2018 May 4;83(9):5160-5176. doi: 10.1021/acs.joc.8b00514. Epub 2018 Apr 26.

PMID:
29644851
6.

The Tripod for Bacterial Natural Product Discovery: Genome Mining, Silent Pathway Induction, and Mass Spectrometry-Based Molecular Networking.

Trivella DBB, de Felicio R.

mSystems. 2018 Mar 27;3(2). pii: e00160-17. doi: 10.1128/mSystems.00160-17. eCollection 2018 Mar-Apr.

7.

Design, Synthesis and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia.

Waechter F, da Silva GNS, Willig JB, de Oliveira CB, Vieira BD, Trivella DBB, Zimmer AR, Buffon A, Pilger DA, Gnoatto SCB.

Anticancer Agents Med Chem. 2017;17(13):1777-1785. doi: 10.2174/1871521409666170412143638.

PMID:
28403779
8.

Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.

Fonseca EM, Trivella DB, Scorsato V, Dias MP, Bazzo NL, Mandapati KR, de Oliveira FL, Ferreira-Halder CV, Pilli RA, Miranda PC, Aparicio R.

Bioorg Med Chem. 2015 Aug 1;23(15):4462-71. doi: 10.1016/j.bmc.2015.06.017. Epub 2015 Jun 14.

PMID:
26117648
9.

Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues.

Carneiro VM, Trivella DB, Scorsato V, Beraldo VL, Dias MP, Sobreira TJ, Aparicio R, Pilli RA.

Eur J Med Chem. 2015 Jun 5;97:42-54. doi: 10.1016/j.ejmech.2015.04.036. Epub 2015 Apr 20.

PMID:
25938987
10.

Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.

Trivella DB, Pereira AR, Stein ML, Kasai Y, Byrum T, Valeriote FA, Tantillo DJ, Groll M, Gerwick WH, Moore BS.

Chem Biol. 2014 Jun 19;21(6):782-91. doi: 10.1016/j.chembiol.2014.04.010. Epub 2014 Jun 12.

11.

Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization.

Bernardes A, Souza PC, Muniz JR, Ricci CG, Ayers SD, Parekh NM, Godoy AS, Trivella DB, Reinach P, Webb P, Skaf MS, Polikarpov I.

J Mol Biol. 2013 Aug 23;425(16):2878-93. doi: 10.1016/j.jmb.2013.05.010. Epub 2013 May 21.

12.

Small-angle X-ray scattering and in silico modeling approaches for the accurate functional annotation of an LysR-type transcriptional regulator.

Toledo MA, Santos CA, Mendes JS, Pelloso AC, Beloti LL, Crucello A, Favaro MT, Santiago AS, Schneider DR, Saraiva AM, Stach-Machado DR, Souza AA, Trivella DB, Aparicio R, Tasic L, Azzoni AR, Souza AP.

Biochim Biophys Acta. 2013 Mar;1834(3):697-707. doi: 10.1016/j.bbapap.2012.12.017. Epub 2013 Jan 5.

PMID:
23298544
13.

Functional and structural studies of the disulfide isomerase DsbC from the plant pathogen Xylella fastidiosa reveals a redox-dependent oligomeric modulation in vitro.

Santos CA, Toledo MA, Trivella DB, Beloti LL, Schneider DR, Saraiva AM, Crucello A, Azzoni AR, Souza AA, Aparicio R, Souza AP.

FEBS J. 2012 Oct;279(20):3828-43. doi: 10.1111/j.1742-4658.2012.08743.x. Epub 2012 Sep 7.

14.

Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis.

Trivella DB, dos Reis CV, Lima LM, Foguel D, Polikarpov I.

J Struct Biol. 2012 Oct;180(1):143-53. doi: 10.1016/j.jsb.2012.07.008. Epub 2012 Jul 25.

15.

Initial crystallographic studies of a small heat-shock protein from Xylella fastidiosa.

Tada SF, Saraiva AM, Lorite GS, Rosselli-Murai LK, Pelloso AC, dos Santos ML, Trivella DB, Cotta MA, de Souza AP, Aparicio R.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 May 1;68(Pt 5):535-9. doi: 10.1107/S1744309112009347. Epub 2012 Apr 20.

16.

Structural insights into human peroxisome proliferator activated receptor delta (PPAR-delta) selective ligand binding.

Batista FA, Trivella DB, Bernardes A, Gratieri J, Oliveira PS, Figueira AC, Webb P, Polikarpov I.

PLoS One. 2012;7(5):e33643. doi: 10.1371/journal.pone.0033643. Epub 2012 May 11.

17.

The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.

Trivella DB, Sairre MI, Foguel D, Lima LM, Polikarpov I.

J Struct Biol. 2011 Feb;173(2):323-32. doi: 10.1016/j.jsb.2010.10.003. Epub 2010 Oct 16.

PMID:
20937391
18.

Structure and function of interleukin-22 and other members of the interleukin-10 family.

Trivella DB, Ferreira-Júnior JR, Dumoutier L, Renauld JC, Polikarpov I.

Cell Mol Life Sci. 2010 Sep;67(17):2909-35. doi: 10.1007/s00018-010-0380-0. Epub 2010 May 8. Review.

PMID:
20454917
19.

Biochemical alterations in caged Nile tilapia Oreochromis niloticus.

Franco JL, Trevisan R, Posser T, Trivella DB, Hoppe R, Martins Rosa J, Fernandes Dinslaken D, Decker H, Inês Tasca C, Bainy Leal R, Freire Marques MR, Dias Bainy AC, Luiz Dafre A.

Ecotoxicol Environ Saf. 2010 Jul;73(5):864-72. doi: 10.1016/j.ecoenv.2010.03.002. Epub 2010 Mar 25.

PMID:
20346509
20.

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.

Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I.

J Struct Biol. 2010 Jun;170(3):522-31. doi: 10.1016/j.jsb.2010.03.002. Epub 2010 Mar 6.

PMID:
20211733
21.

Antioxidant status and stress proteins in the gills of the brown mussel Perna perna exposed to zinc.

Franco JL, Trivella DB, Trevisan R, Dinslaken DF, Marques MR, Bainy AC, Dafre AL.

Chem Biol Interact. 2006 Apr 15;160(3):232-40. Epub 2006 Mar 24.

PMID:
16564039

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