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Items: 28

1.

RPC4046, A Novel Anti-interleukin-13 Antibody, Blocks IL-13 Binding to IL-13 α1 and α2 Receptors: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation First-in-Human Study.

Tripp CS, Cuff C, Campbell AL, Hendrickson BA, Voss J, Melim T, Wu C, Cherniack AD, Kim K.

Adv Ther. 2017 Jun;34(6):1364-1381. doi: 10.1007/s12325-017-0525-8. Epub 2017 Apr 28.

2.

Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship.

Bonafoux DF, Bonar SL, Clare M, Donnelly AM, Glaenzer JL, Guzova JA, Huang H, Kishore NN, Koszyk FJ, Lennon PJ, Libby A, Mathialagan S, Oburn DS, Rouw SA, Sommers CD, Tripp CS, Vanella LJ, Weier R, Wolfson SG, Huang HC.

Bioorg Med Chem. 2010 Jan 1;18(1):403-14. doi: 10.1016/j.bmc.2009.10.040. Epub 2009 Oct 27.

PMID:
19914076
3.

A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal models.

Mbalaviele G, Sommers CD, Bonar SL, Mathialagan S, Schindler JF, Guzova JA, Shaffer AF, Melton MA, Christine LJ, Tripp CS, Chiang PC, Thompson DC, Hu Y, Kishore N.

J Pharmacol Exp Ther. 2009 Apr;329(1):14-25. doi: 10.1124/jpet.108.143800. Epub 2009 Jan 23.

PMID:
19168710
4.

Pillars article: development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. 1993. Science 260(5107): 547-549.

Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM.

J Immunol. 2008 Oct 1;181(7):4437-9. No abstract available.

5.

Regulation and phenotype of an innate Th1 cell: role of cytokines and the p38 kinase pathway.

Yu JJ, Tripp CS, Russell JH.

J Immunol. 2003 Dec 1;171(11):6112-8.

6.

Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection.

Tripp CS, Blomme EA, Chinn KS, Hardy MM, LaCelle P, Pentland AP.

J Invest Dermatol. 2003 Oct;121(4):853-61.

7.

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts.

Kishore N, Sommers C, Mathialagan S, Guzova J, Yao M, Hauser S, Huynh K, Bonar S, Mielke C, Albee L, Weier R, Graneto M, Hanau C, Perry T, Tripp CS.

J Biol Chem. 2003 Aug 29;278(35):32861-71. Epub 2003 Jun 17.

8.

Selective cyclooxygenase-2 inhibition does not alter keratinocyte wound responses in the mouse epidermis after abrasion.

Hardy MM, Blomme EA, Lisowski A, Chinn KS, Jones A, Harmon JM, Opsahl A, Ornberg RL, Tripp CS.

J Pharmacol Exp Ther. 2003 Mar;304(3):959-67.

PMID:
12604670
9.

Selective cyclooxygenase-2 inhibition does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice.

Blomme EA, Chinn KS, Hardy MM, Casler JJ, Kim SH, Opsahl AC, Hall WA, Trajkovic D, Khan KN, Tripp CS.

Br J Dermatol. 2003 Feb;148(2):211-23.

PMID:
12588370
10.

Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants.

Hardy MM, Seibert K, Manning PT, Currie MG, Woerner BM, Edwards D, Koki A, Tripp CS.

Arthritis Rheum. 2002 Jul;46(7):1789-803.

11.

IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2.

Kishore N, Huynh QK, Mathialagan S, Hall T, Rouw S, Creely D, Lange G, Caroll J, Reitz B, Donnelly A, Boddupalli H, Combs RG, Kretzmer K, Tripp CS.

J Biol Chem. 2002 Apr 19;277(16):13840-7. Epub 2002 Feb 11.

12.

Kinetic mechanisms of IkappaB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer.

Huynh QK, Kishore N, Mathialagan S, Donnelly AM, Tripp CS.

J Biol Chem. 2002 Apr 12;277(15):12550-8. Epub 2002 Jan 28.

13.

Characterization of the recombinant IKK1/IKK2 heterodimer. Mechanisms regulating kinase activity.

Huynh QK, Boddupalli H, Rouw SA, Koboldt CM, Hall T, Sommers C, Hauser SD, Pierce JL, Combs RG, Reitz BA, Diaz-Collier JA, Weinberg RA, Hood BL, Kilpatrick BF, Tripp CS.

J Biol Chem. 2000 Aug 25;275(34):25883-91.

14.

Secondary response to Listeria infection requires IFN-gamma but is partially independent of IL-12.

Tripp CS, Kanagawa O, Unanue ER.

J Immunol. 1995 Oct 1;155(7):3427-32.

PMID:
7561037
15.

Macrophage production of IL12 is a critical link between the innate and specific immune responses to Listeria.

Tripp CS, Unanue ER.

Res Immunol. 1995 Sep-Oct;146(7-8):515-20. Review. No abstract available.

PMID:
8839155
17.

Endogenous IL-1 is required for neutrophil recruitment and macrophage activation during murine listeriosis.

Rogers HW, Tripp CS, Schreiber RD, Unanue ER.

J Immunol. 1994 Sep 1;153(5):2093-101.

PMID:
8051414
18.

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

Tripp CS, Gately MK, Hakimi J, Ling P, Unanue ER.

J Immunol. 1994 Feb 15;152(4):1883-7.

PMID:
7907107
19.

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages.

Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM.

Science. 1993 Apr 23;260(5107):547-9.

PMID:
8097338
21.
23.

Regulation of macrophage arachidonic acid metabolism during the immune response.

Tripp CS, Needleman P.

Adv Prostaglandin Thromboxane Leukot Res. 1987;17B:1085-90. No abstract available.

PMID:
2960149
24.

The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro.

Tripp CS, Wyche A, Unanue ER, Needleman P.

J Immunol. 1986 Dec 15;137(12):3915-20.

PMID:
3097136
25.

Monocyte migration explains the changes in macrophage arachidonate metabolism during the immune response.

Tripp CS, Unanue ER, Needleman P.

Proc Natl Acad Sci U S A. 1986 Dec;83(24):9655-9.

26.

Thromboxane synthase is preferentially conserved in activated mouse peritoneal macrophages.

Tripp CS, Leahy KM, Needleman P.

J Clin Invest. 1985 Aug;76(2):898-901.

27.

Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase.

Tripp CS, Mahoney M, Needleman P.

J Biol Chem. 1985 May 25;260(10):5895-8.

28.

Synthetic glycopeptide substrates for receptor-mediated endocytosis by macrophages.

Robbins JC, Lam MH, Tripp CS, Bugianesi RL, Ponpipom MM, Shen TY.

Proc Natl Acad Sci U S A. 1981 Dec;78(12):7294-8.

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