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Items: 1 to 50 of 424

1.

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.

Koyama M, Mukhopadhyay P, Schuster IS, Henden AS, Hülsdünker J, Varelias A, Vetizou M, Kuns RD, Robb RJ, Zhang P, Blazar BR, Thomas R, Begun J, Waddell N, Trinchieri G, Zeiser R, Clouston AD, Degli-Esposti MA, Hill GR.

Immunity. 2019 Sep 18. pii: S1074-7613(19)30362-0. doi: 10.1016/j.immuni.2019.08.011. [Epub ahead of print]

PMID:
31542340
2.

Microbiome as an Immunological Modifier.

Kumar M, Singh P, Murugesan S, Vetizou M, McCulloch J, Badger JH, Trinchieri G, Al Khodor S.

Methods Mol Biol. 2020;2055:595-638. doi: 10.1007/978-1-4939-9773-2_27.

PMID:
31502171
3.

Laboratory mice born to wild mice have natural microbiota and model human immune responses.

Rosshart SP, Herz J, Vassallo BG, Hunter A, Wall MK, Badger JH, McCulloch JA, Anastasakis DG, Sarshad AA, Leonardi I, Collins N, Blatter JA, Han SJ, Tamoutounour S, Potapova S, Foster St Claire MB, Yuan W, Sen SK, Dreier MS, Hild B, Hafner M, Wang D, Iliev ID, Belkaid Y, Trinchieri G, Rehermann B.

Science. 2019 Aug 2;365(6452). pii: eaaw4361. doi: 10.1126/science.aaw4361. Epub 2019 Aug 1.

PMID:
31371577
4.

Cancer cachexia induces morphological and inflammatory changes in the intestinal mucosa.

Costa RGF, Caro PL, de Matos-Neto EM, Lima JDCC, Radloff K, Alves MJ, Camargo RG, Pessoa AFM, Simoes E, Gama P, Cara DC, da Silva ASF, O Pereira W, Maximiano LF, de Alcântara PSM, Otoch JP, Trinchieri G, Laviano A, Muscaritoli M, Seelaender M.

J Cachexia Sarcopenia Muscle. 2019 Jul 15. doi: 10.1002/jcsm.12449. [Epub ahead of print]

5.

The cancer microbiome.

Elinav E, Garrett WS, Trinchieri G, Wargo J.

Nat Rev Cancer. 2019 Jul;19(7):371-376. doi: 10.1038/s41568-019-0155-3. Epub 2019 Jun 11. Review.

PMID:
31186547
6.

Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques.

Namasivayam S, Kauffman KD, McCulloch JA, Yuan W, Thovarai V, Mittereder LR, Trinchieri G, Barber DL, Sher A.

MBio. 2019 Jun 4;10(3). pii: e01018-19. doi: 10.1128/mBio.01018-19.

7.

T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis.

Cataisson C, Salcedo R, Michalowski AM, Klosterman M, Naik S, Li L, Pan MJ, Sweet A, Chen JQ, Kostecka LG, Karwan M, Smith L, Dai RM, Stewart CA, Lyakh L, Hsieh WT, Khan A, Yang H, Lee M, Trinchieri G, Yuspa SH.

Mol Cancer Res. 2019 Aug;17(8):1759-1773. doi: 10.1158/1541-7786.MCR-19-0227. Epub 2019 Jun 4.

PMID:
31164412
8.

Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response.

Sui Y, Lewis GK, Wang Y, Berckmueller K, Frey B, Dzutsev A, Vargas-Inchaustegui D, Mohanram V, Musich T, Shen X, DeVico A, Fouts T, Venzon D, Kirk J, Waters RC, Talton J, Klinman D, Clements J, Tomaras GD, Franchini G, Robert-Guroff M, Trinchieri G, Gallo RC, Berzofsky JA.

J Clin Invest. 2019 Mar 1;129(3):1314-1328. doi: 10.1172/JCI122110. Epub 2019 Feb 18.

9.

Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.

Dmitrieva-Posocco O, Dzutsev A, Posocco DF, Hou V, Yuan W, Thovarai V, Mufazalov IA, Gunzer M, Shilovskiy IP, Khaitov MR, Trinchieri G, Waisman A, Grivennikov SI.

Immunity. 2019 Jan 15;50(1):166-180.e7. doi: 10.1016/j.immuni.2018.11.015.

PMID:
30650375
10.

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells.

Bodogai M, O'Connell J, Kim K, Kim Y, Moritoh K, Chen C, Gusev F, Vaughan K, Shulzhenko N, Mattison JA, Lee-Chang C, Chen W, Carlson O, Becker KG, Gurung M, Morgun A, White J, Meade T, Perdue K, Mack M, Ferrucci L, Trinchieri G, de Cabo R, Rogaev E, Egan J, Wu J, Biragyn A.

Sci Transl Med. 2018 Nov 14;10(467). pii: eaat4271. doi: 10.1126/scitranslmed.aat4271.

11.

An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis.

Fatkhullina AR, Peshkova IO, Dzutsev A, Aghayev T, McCulloch JA, Thovarai V, Badger JH, Vats R, Sundd P, Tang HY, Kossenkov AV, Hazen SL, Trinchieri G, Grivennikov SI, Koltsova EK.

Immunity. 2018 Nov 20;49(5):943-957.e9. doi: 10.1016/j.immuni.2018.09.011. Epub 2018 Oct 30.

PMID:
30389414
12.

A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans.

Dutzan N, Kajikawa T, Abusleme L, Greenwell-Wild T, Zuazo CE, Ikeuchi T, Brenchley L, Abe T, Hurabielle C, Martin D, Morell RJ, Freeman AF, Lazarevic V, Trinchieri G, Diaz PI, Holland SM, Belkaid Y, Hajishengallis G, Moutsopoulos NM.

Sci Transl Med. 2018 Oct 17;10(463). pii: eaat0797. doi: 10.1126/scitranslmed.aat0797.

PMID:
30333238
13.

Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells.

Abdi K, Laky K, Padhan K, Petrovas C, Skinner J, Kabat J, Dorward DW, Brzostowski J, Long EO, Trinchieri G, Varma R.

J Immunol. 2018 Nov 15;201(10):2879-2884. doi: 10.4049/jimmunol.1800721. Epub 2018 Oct 12.

14.

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.

Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, Grau M, Macari C, Bauché D, Dumitrescu O, Rasigade JP, Lippens S, Plateroti M, Kress E, Cesaro A, Bondu C, Rothermel U, Heikenwälder M, Lina G, Bentaher-Belaaouaj A, Marie JC, Caux C, Trinchieri G, Marvel J, Michallet MC.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10404-10409. doi: 10.1073/pnas.1722372115. Epub 2018 Sep 24.

15.

Interaction between the microbiome and TP53 in human lung cancer.

Greathouse KL, White JR, Vargas AJ, Bliskovsky VV, Beck JA, von Muhlinen N, Polley EC, Bowman ED, Khan MA, Robles AI, Cooks T, Ryan BM, Padgett N, Dzutsev AH, Trinchieri G, Pineda MA, Bilke S, Meltzer PS, Hokenstad AN, Stickrod TM, Walther-Antonio MR, Earl JP, Mell JC, Krol JE, Balashov SV, Bhat AS, Ehrlich GD, Valm A, Deming C, Conlan S, Oh J, Segre JA, Harris CC.

Genome Biol. 2018 Aug 24;19(1):123. doi: 10.1186/s13059-018-1501-6.

16.

The innate immune receptor TREM-1 promotes liver injury and fibrosis.

Nguyen-Lefebvre AT, Ajith A, Portik-Dobos V, Horuzsko DD, Arbab AS, Dzutsev A, Sadek R, Trinchieri G, Horuzsko A.

J Clin Invest. 2018 Nov 1;128(11):4870-4883. doi: 10.1172/JCI98156. Epub 2018 Oct 2.

17.

Workshop Report: Modulation of Antitumor Immune Responses by Dietary and Microbial Metabolites.

Kumar A, Smith C, Jobin C, Trinchieri G, Howcroft TK, Seifried H, Espey MG, Flores R, Kim YS, Daschner PJ.

J Natl Cancer Inst. 2017 Jun 1;109(6). doi: 10.1093/jnci/djx040.

18.

The interplay between neutrophils and microbiota in cancer.

Smith CK, Trinchieri G.

J Leukoc Biol. 2018 Oct;104(4):701-715. doi: 10.1002/JLB.4RI0418-151R. Epub 2018 Jul 25. Review.

PMID:
30044897
19.

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques.

Sui Y, Dzutsev A, Venzon D, Frey B, Thovarai V, Trinchieri G, Berzofsky JA.

Mucosal Immunol. 2018 Jul;11(4):1219-1229. doi: 10.1038/s41385-018-0029-0. Epub 2018 Jun 1.

20.

Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.

Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF.

Science. 2018 May 25;360(6391). pii: eaan5931. doi: 10.1126/science.aan5931.

21.

Natural Killer Cells Detect a Tumor-Produced Growth Factor: A Vestige of Antiviral Resistance?

Trinchieri G.

Trends Immunol. 2018 May;39(5):357-358. doi: 10.1016/j.it.2018.02.002. Epub 2018 Feb 22.

PMID:
29478770
22.

The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance.

Yoshimura T, McLean MH, Dzutsev AK, Yao X, Chen K, Huang J, Gong W, Zhou J, Xiang Y, H Badger J, O'hUigin C, Thovarai V, Tessarollo L, Durum SK, Trinchieri G, Bian XW, Wang JM.

J Immunol. 2018 Mar 15;200(6):2174-2185. doi: 10.4049/jimmunol.1602073. Epub 2018 Feb 12.

23.

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.

Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y.

Cell. 2018 Feb 8;172(4):784-796.e18. doi: 10.1016/j.cell.2017.12.033. Epub 2018 Jan 18.

24.

Anti-PD1 in the wonder-gut-land.

Vetizou M, Trinchieri G.

Cell Res. 2018 Mar;28(3):263-264. doi: 10.1038/cr.2018.12. Epub 2018 Jan 16.

25.

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.

Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B.

Cell. 2017 Nov 16;171(5):1015-1028.e13. doi: 10.1016/j.cell.2017.09.016. Epub 2017 Oct 19.

26.

Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy.

Namasivayam S, Maiga M, Yuan W, Thovarai V, Costa DL, Mittereder LR, Wipperman MF, Glickman MS, Dzutsev A, Trinchieri G, Sher A.

Microbiome. 2017 Jul 7;5(1):71. doi: 10.1186/s40168-017-0286-2.

27.

Systematic evaluation of immune regulation and modulation.

Stroncek DF, Butterfield LH, Cannarile MA, Dhodapkar MV, Greten TF, Grivel JC, Kaufman DR, Kong HH, Korangy F, Lee PP, Marincola F, Rutella S, Siebert JC, Trinchieri G, Seliger B.

J Immunother Cancer. 2017 Mar 21;5:21. doi: 10.1186/s40425-017-0223-8. eCollection 2017. Review.

28.

Microbiota: a key orchestrator of cancer therapy.

Roy S, Trinchieri G.

Nat Rev Cancer. 2017 May;17(5):271-285. doi: 10.1038/nrc.2017.13. Epub 2017 Mar 17. Review.

PMID:
28303904
29.

Microbes and Cancer.

Dzutsev A, Badger JH, Perez-Chanona E, Roy S, Salcedo R, Smith CK, Trinchieri G.

Annu Rev Immunol. 2017 Apr 26;35:199-228. doi: 10.1146/annurev-immunol-051116-052133. Epub 2017 Jan 30. Review.

PMID:
28142322
30.

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.

Dutzan N, Abusleme L, Bridgeman H, Greenwell-Wild T, Zangerle-Murray T, Fife ME, Bouladoux N, Linley H, Brenchley L, Wemyss K, Calderon G, Hong BY, Break TJ, Bowdish DME, Lionakis MS, Jones SA, Trinchieri G, Diaz PI, Belkaid Y, Konkel JE, Moutsopoulos NM.

Immunity. 2017 Jan 17;46(1):133-147. doi: 10.1016/j.immuni.2016.12.010. Epub 2017 Jan 10.

31.

The role of microbiota in cancer therapy.

Perez-Chanona E, Trinchieri G.

Curr Opin Immunol. 2016 Apr;39:75-81. doi: 10.1016/j.coi.2016.01.003. Epub 2016 Jan 26. Review.

32.

Systemic Inflammation in Cachexia - Is Tumor Cytokine Expression Profile the Culprit?

de Matos-Neto EM, Lima JD, de Pereira WO, Figuerêdo RG, Riccardi DM, Radloff K, das Neves RX, Camargo RG, Maximiano LF, Tokeshi F, Otoch JP, Goldszmid R, Câmara NO, Trinchieri G, de Alcântara PS, Seelaender M.

Front Immunol. 2015 Dec 24;6:629. doi: 10.3389/fimmu.2015.00629. eCollection 2015.

33.

Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity.

Fonseca DM, Hand TW, Han SJ, Gerner MY, Glatman Zaretsky A, Byrd AL, Harrison OJ, Ortiz AM, Quinones M, Trinchieri G, Brenchley JM, Brodsky IE, Germain RN, Randolph GJ, Belkaid Y.

Cell. 2015 Oct 8;163(2):354-66. doi: 10.1016/j.cell.2015.08.030.

34.

Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells.

Bodogai M, Moritoh K, Lee-Chang C, Hollander CM, Sherman-Baust CA, Wersto RP, Araki Y, Miyoshi I, Yang L, Trinchieri G, Biragyn A.

Cancer Res. 2015 Sep 1;75(17):3456-65. doi: 10.1158/0008-5472.CAN-14-3077. Epub 2015 Jul 16.

35.

Cancer Immunity: Lessons From Infectious Diseases.

Trinchieri G.

J Infect Dis. 2015 Jul 15;212 Suppl 1:S67-73. doi: 10.1093/infdis/jiv070.

36.

Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection.

Askenase MH, Han SJ, Byrd AL, Morais da Fonseca D, Bouladoux N, Wilhelm C, Konkel JE, Hand TW, Lacerda-Queiroz N, Su XZ, Trinchieri G, Grainger JR, Belkaid Y.

Immunity. 2015 Jun 16;42(6):1130-42. doi: 10.1016/j.immuni.2015.05.011. Epub 2015 Jun 9.

37.

Identifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichment.

Levay A, Brenneman R, Hoinka J, Sant D, Cardone M, Trinchieri G, Przytycka TM, Berezhnoy A.

Nucleic Acids Res. 2015 Jul 13;43(12):e82. doi: 10.1093/nar/gkv534. Epub 2015 May 24.

38.

NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay.

Ridnour LA, Cheng RY, Weiss JM, Kaur S, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart CA, DeGraff W, Sowers AL, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA.

Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19.

39.

Proteus mirabilis: The Enemy Within.

Dzutsev A, Trinchieri G.

Immunity. 2015 Apr 21;42(4):602-4. doi: 10.1016/j.immuni.2015.04.004.

40.

Microbiota modulation of myeloid cells in cancer therapy.

Goldszmid RS, Dzutsev A, Viaud S, Zitvogel L, Restifo NP, Trinchieri G.

Cancer Immunol Res. 2015 Feb;3(2):103-9. doi: 10.1158/2326-6066.CIR-14-0225. Review.

41.

Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.

Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, Goldszmid R, McVicar DW, Lyakh L, Trinchieri G.

PLoS One. 2014 Dec 4;9(12):e114516. doi: 10.1371/journal.pone.0114516. eCollection 2014.

42.

The role of the microbiota in inflammation, carcinogenesis, and cancer therapy.

Dzutsev A, Goldszmid RS, Viaud S, Zitvogel L, Trinchieri G.

Eur J Immunol. 2015 Jan;45(1):17-31. doi: 10.1002/eji.201444972. Epub 2014 Nov 13. Review.

43.

Harnessing the intestinal microbiome for optimal therapeutic immunomodulation.

Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L.

Cancer Res. 2014 Aug 15;74(16):4217-21. doi: 10.1158/0008-5472.CAN-14-0987. Epub 2014 Jul 29. Review.

44.

Critical role for CX₃CR1⁺ mononuclear phagocytes in intestinal homeostasis.

Trinchieri G.

J Exp Med. 2014 Jul 28;211(8):1500-1. doi: 10.1084/jem.2118insight2. No abstract available.

45.

Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens.

Thomas JM, Pos Z, Reinboth J, Wang RY, Wang E, Frank GM, Lusso P, Trinchieri G, Alter HJ, Marincola FM, Thomas E.

J Virol. 2014 Sep;88(18):10758-66. doi: 10.1128/JVI.01501-14. Epub 2014 Jul 9.

46.

Gut microbiome and anticancer immune response: really hot Sh*t!

Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L.

Cell Death Differ. 2015 Feb;22(2):199-214. doi: 10.1038/cdd.2014.56. Epub 2014 May 16. Review.

47.

Why should we need the gut microbiota to respond to cancer therapies?

Viaud S, Daillère R, Yamazaki T, Lepage P, Boneca I, Goldszmid R, Trinchieri G, Zitvogel L.

Oncoimmunology. 2014 Jan 1;3(1):e27574. Epub 2014 Jan 17.

48.

Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells.

Swiecki M, Wang Y, Riboldi E, Kim AH, Dzutsev A, Gilfillan S, Vermi W, Ruedl C, Trinchieri G, Colonna M.

J Immunol. 2014 May 1;192(9):4409-16. doi: 10.4049/jimmunol.1303135. Epub 2014 Mar 28.

49.

Host immune response to infection and cancer: unexpected commonalities.

Goldszmid RS, Dzutsev A, Trinchieri G.

Cell Host Microbe. 2014 Mar 12;15(3):295-305. doi: 10.1016/j.chom.2014.02.003. Review.

50.

A new VEGF connection between two old neighbors.

Cella M, Trinchieri G.

Nat Immunol. 2014 Jan;15(1):8-9. doi: 10.1038/ni.2786. No abstract available.

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