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Items: 29

1.

Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia.

Kourtis N, Lazaris C, Hockemeyer K, Balandrán JC, Jimenez AR, Mullenders J, Gong Y, Trimarchi T, Bhatt K, Hu H, Shrestha L, Ambesi-Impiombato A, Kelliher M, Paietta E, Chiosis G, Guzman ML, Ferrando AA, Tsirigos A, Aifantis I.

Nat Med. 2018 Aug;24(8):1157-1166. doi: 10.1038/s41591-018-0105-8. Epub 2018 Jul 23.

2.

lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets.

Gong Y, Huang HT, Liang Y, Trimarchi T, Aifantis I, Tsirigos A.

BMC Genomics. 2017 Jun 5;18(1):434. doi: 10.1186/s12864-017-3817-0.

3.

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.

Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I.

Nat Cell Biol. 2016 Nov;18(11):1127-1138. doi: 10.1038/ncb3424. Epub 2016 Oct 17.

4.

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation.

Proudhon C, Snetkova V, Raviram R, Lobry C, Badri S, Jiang T, Hao B, Trimarchi T, Kluger Y, Aifantis I, Bonneau R, Skok JA.

Cell Rep. 2016 Jun 7;15(10):2159-2169. doi: 10.1016/j.celrep.2016.04.087. Epub 2016 May 26.

5.

Erratum: TET1 is a tumor suppressor of hematopoietic malignancy.

Cimmino L, Dawlaty MM, Ndiaye-Lobry D, Yap YS, Bakogianni S, Yu Y, Bhattacharyya S, Shaknovich R, Geng H, Lobry C, Mullenders J, King B, Trimarchi T, Aranda-Orgilles B, Liu C, Shen S, Verma AK, Jaenisch R, Aifantis I.

Nat Immunol. 2015 Aug;16(8):889. doi: 10.1038/ni0815-889a. No abstract available.

PMID:
26194287
6.

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.

Pitt LA, Tikhonova AN, Hu H, Trimarchi T, King B, Gong Y, Sanchez-Martin M, Tsirigos A, Littman DR, Ferrando AA, Morrison SJ, Fooksman DR, Aifantis I, Schwab SR.

Cancer Cell. 2015 Jun 8;27(6):755-68. doi: 10.1016/j.ccell.2015.05.002.

7.

TET1 is a tumor suppressor of hematopoietic malignancy.

Cimmino L, Dawlaty MM, Ndiaye-Lobry D, Yap YS, Bakogianni S, Yu Y, Bhattacharyya S, Shaknovich R, Geng H, Lobry C, Mullenders J, King B, Trimarchi T, Aranda-Orgilles B, Liu C, Shen S, Verma AK, Jaenisch R, Aifantis I.

Nat Immunol. 2015 Jun;16(6):653-62. doi: 10.1038/ni.3148. Epub 2015 Apr 13. Erratum in: Nat Immunol. 2015 Aug;16(8):889.

8.

The pre-BCR to the rescue: therapeutic targeting of pre-B cell ALL.

Trimarchi T, Aifantis I.

Cancer Cell. 2015 Mar 9;27(3):321-3. doi: 10.1016/j.ccell.2015.02.012.

9.

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.

Kourtis N, Moubarak RS, Aranda-Orgilles B, Lui K, Aydin IT, Trimarchi T, Darvishian F, Salvaggio C, Zhong J, Bhatt K, Chen EI, Celebi JT, Lazaris C, Tsirigos A, Osman I, Hernando E, Aifantis I.

Nat Cell Biol. 2015 Mar;17(3):322-332. doi: 10.1038/ncb3121.

10.

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.

Witkowski MT, Cimmino L, Hu Y, Trimarchi T, Tagoh H, McKenzie MD, Best SA, Tuohey L, Willson TA, Nutt SL, Busslinger M, Aifantis I, Smyth GK, Dickins RA.

Leukemia. 2015 Jun;29(6):1301-11. doi: 10.1038/leu.2015.27. Epub 2015 Feb 6.

11.

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.

Ntziachristos P, Tsirigos A, Welstead GG, Trimarchi T, Bakogianni S, Xu L, Loizou E, Holmfeldt L, Strikoudis A, King B, Mullenders J, Becksfort J, Nedjic J, Paietta E, Tallman MS, Rowe JM, Tonon G, Satoh T, Kruidenier L, Prinjha R, Akira S, Van Vlierberghe P, Ferrando AA, Jaenisch R, Mullighan CG, Aifantis I.

Nature. 2014 Oct 23;514(7523):513-7. doi: 10.1038/nature13605. Epub 2014 Aug 17.

12.

Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia.

Trimarchi T, Bilal E, Ntziachristos P, Fabbri G, Dalla-Favera R, Tsirigos A, Aifantis I.

Cell. 2014 Jul 31;158(3):593-606. doi: 10.1016/j.cell.2014.05.049.

13.

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.

Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL.

J Exp Med. 2013 Nov 18;210(12):2641-59. doi: 10.1084/jem.20131141. Epub 2013 Nov 11.

14.

A new player SETs in myeloid malignancy.

Trimarchi T, Ntziachristos P, Aifantis I.

Nat Genet. 2013 Aug;45(8):846-7. doi: 10.1038/ng.2709.

15.

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.

King B, Trimarchi T, Reavie L, Xu L, Mullenders J, Ntziachristos P, Aranda-Orgilles B, Perez-Garcia A, Shi J, Vakoc C, Sandy P, Shen SS, Ferrando A, Aifantis I.

Cell. 2013 Jun 20;153(7):1552-66. doi: 10.1016/j.cell.2013.05.041.

16.

Mechanisms of epigenetic regulation of leukemia onset and progression.

Ntziachristos P, Mullenders J, Trimarchi T, Aifantis I.

Adv Immunol. 2013;117:1-38. doi: 10.1016/B978-0-12-410524-9.00001-3. Review.

17.

Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.

Sawai CM, Freund J, Oh P, Ndiaye-Lobry D, Bretz JC, Strikoudis A, Genesca L, Trimarchi T, Kelliher MA, Clark M, Soulier J, Chen-Kiang S, Aifantis I.

Cancer Cell. 2012 Oct 16;22(4):452-65. doi: 10.1016/j.ccr.2012.09.016.

18.

Close proximity to Igh is a contributing factor to AID-mediated translocations.

Rocha PP, Micsinai M, Kim JR, Hewitt SL, Souza PP, Trimarchi T, Strino F, Parisi F, Kluger Y, Skok JA.

Mol Cell. 2012 Sep 28;47(6):873-85. doi: 10.1016/j.molcel.2012.06.036. Epub 2012 Aug 2.

19.

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.

Ntziachristos P, Tsirigos A, Van Vlierberghe P, Nedjic J, Trimarchi T, Flaherty MS, Ferres-Marco D, da Ros V, Tang Z, Siegle J, Asp P, Hadler M, Rigo I, De Keersmaecker K, Patel J, Huynh T, Utro F, Poglio S, Samon JB, Paietta E, Racevskis J, Rowe JM, Rabadan R, Levine RL, Brown S, Pflumio F, Dominguez M, Ferrando A, Aifantis I.

Nat Med. 2012 Feb 6;18(2):298-301. doi: 10.1038/nm.2651.

20.

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, Taghon T, Michor F, Levine RL, Aifantis I.

Nature. 2011 May 12;473(7346):230-3. doi: 10.1038/nature09999.

21.

Thromboprophylaxis in a pediatric hospital: a patient-safety and quality-improvement initiative.

Raffini L, Trimarchi T, Beliveau J, Davis D.

Pediatrics. 2011 May;127(5):e1326-32. doi: 10.1542/peds.2010-3282. Epub 2011 Apr 4.

PMID:
21464186
22.

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

Espinosa L, Cathelin S, D'Altri T, Trimarchi T, Statnikov A, Guiu J, Rodilla V, Inglés-Esteve J, Nomdedeu J, Bellosillo B, Besses C, Abdel-Wahab O, Kucine N, Sun SC, Song G, Mullighan CC, Levine RL, Rajewsky K, Aifantis I, Bigas A.

Cancer Cell. 2010 Sep 14;18(3):268-81. doi: 10.1016/j.ccr.2010.08.006.

23.

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.

Buonamici S, Trimarchi T, Ruocco MG, Reavie L, Cathelin S, Mar BG, Klinakis A, Lukyanov Y, Tseng JC, Sen F, Gehrie E, Li M, Newcomb E, Zavadil J, Meruelo D, Lipp M, Ibrahim S, Efstratiadis A, Zagzag D, Bromberg JS, Dustin ML, Aifantis I.

Nature. 2009 Jun 18;459(7249):1000-4. doi: 10.1038/nature08020.

24.

Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury.

Suratt BT, Eisner MD, Calfee CS, Allard JB, Whittaker LA, Engelken DT, Petty JM, Trimarchi T, Gauthier L, Parsons PE; NHLBI Acute Respiratory Distress Syndrome Network.

Crit Care Med. 2009 Apr;37(4):1322-8. doi: 10.1097/CCM.0b013e31819c14fa.

25.

CNTF-evoked activation of JAK and ERK mediates the functional expression of T-type Ca2+ channels in chicken nodose neurons.

Trimarchi T, Pachuau J, Shepherd A, Dey D, Martin-Caraballo M.

J Neurochem. 2009 Jan;108(1):246-59. doi: 10.1111/j.1471-4159.2008.05759.x. Epub 2008 Nov 21.

26.

Inhibition of electrical activity by retroviral infection with Kir2.1 transgenes disrupts electrical differentiation of motoneurons.

Yoon YJ, Kominami H, Trimarchi T, Martin-Caraballo M.

PLoS One. 2008 Aug 13;3(8):e2971. doi: 10.1371/journal.pone.0002971.

27.

Endocrine problems in critically ill children: an overview.

Trimarchi T.

AACN Clin Issues. 2006 Jan-Mar;17(1):66-78. Review.

PMID:
16462411
28.

Obstructive sleep apnea syndrome in children.

Bandla P, Brooks LJ, Trimarchi T, Helfaer M.

Anesthesiol Clin North Am. 2005 Sep;23(3):535-49, viii. Review.

PMID:
16005829
29.

Challenges of advanced practice nursing in pediatric acute and critical care: education to practice.

Verger J, Trimarchi T, Barnsteiner JH.

Crit Care Nurs Clin North Am. 2002 Sep;14(3):315-26. Review.

PMID:
12168712

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