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Items: 1 to 50 of 246

1.

From Gutenberg to Open Science: An Unfulfilled Odyssey.

Triggle CR, Triggle DJ.

Drug Dev Res. 2017 Feb;78(1):3-23. doi: 10.1002/ddr.21369. Epub 2016 Oct 21.

2.

Nous sommes tous des bacteries: implications for medicine, pharmacology and public health.

Triggle DJ.

Biochem Pharmacol. 2012 Dec 15;84(12):1543-50. doi: 10.1016/j.bcp.2012.08.005. Epub 2012 Aug 15.

PMID:
22902418
3.

The chemist as astronaut: searching for biologically useful space in the chemical universe.

Triggle DJ.

Biochem Pharmacol. 2009 Aug 1;78(3):217-23. doi: 10.1016/j.bcp.2009.02.015. Epub 2009 Mar 5.

PMID:
19481639
5.

Calcium channel antagonists: clinical uses--past, present and future.

Triggle DJ.

Biochem Pharmacol. 2007 Jun 30;74(1):1-9. Epub 2007 Jan 13. Review.

PMID:
17276408
6.

Treating desires not diseases: a pill for every ill and an ill for every pill?

Triggle DJ.

Drug Discov Today. 2007 Feb;12(3-4):161-6. Epub 2006 Dec 22. Review. No abstract available.

PMID:
17275737
7.

Drug discovery and delivery in the 21st century.

Triggle DJ.

Med Princ Pract. 2007;16(1):1-14. Review.

8.

L-type calcium channels.

Triggle DJ.

Curr Pharm Des. 2006;12(4):443-57. Review.

PMID:
16472138
9.

Everybody must get cloned: ideological objections do not hold up.

Triggle DJ.

Free Inq. 2002-2003 Winter;23(1):32-3. No abstract available.

PMID:
16208834
10.

Addiction.

Triggle DJ.

IDrugs. 1999 Nov;2(11):1099-101. No abstract available.

PMID:
16113970
11.

Division of Medicinal Chemistry--integrins: past, present and future.

Rotella DP, Triggle DJ.

IDrugs. 2000 Nov;3(11):1274-6. No abstract available.

PMID:
16047233
12.

Noordwijkerhout-Camerino--15th Symposium. Trends in drug research.

Triggle DJ.

IDrugs. 2005 Jul;8(7):563-6. No abstract available.

PMID:
15973564
13.

Mechanism of tissue-selective drug action in the cardiovascular system.

Barrett TD, Triggle DJ, Walker MJ, Maurice DH.

Mol Interv. 2005 Apr;5(2):84-93. Review.

PMID:
15821157
14.

Drug targets in the voltage-gated calcium channel family: why some are and some are not.

Triggle DJ.

Assay Drug Dev Technol. 2003 Oct;1(5):719-33. Review.

PMID:
15090244
15.

1,4-Dihydropyridines as calcium channel ligands and privileged structures.

Triggle DJ.

Cell Mol Neurobiol. 2003 Jun;23(3):293-303. Review.

PMID:
12825828
16.

The 1,4-dihydropyridine nucleus: a pharmacophoric template part 1. Actions at ion channels.

Triggle DJ.

Mini Rev Med Chem. 2003 May;3(3):215-23. Review.

PMID:
12570837
17.

Interaction of azimilide with neurohumoral and channel receptors.

Brooks RR, Pong SF, Izzo NJ, Moorehead TJ, Gopalakrishnan M, Triggle DJ.

Biochem Pharmacol. 2001 Oct 1;62(7):883-92.

PMID:
11543723
18.

Regulation of L-type calcium channels in pituitary GH(4)C(1) cells by depolarization.

Peri R, Triggle DJ, Singh S.

J Biol Chem. 2001 Aug 24;276(34):31667-73. Epub 2001 Jun 18.

19.

Overview of chemical diversity.

Triggle DJ.

Curr Protoc Pharmacol. 2001 May;Chapter 9:Unit 9.1. doi: 10.1002/0471141755.ph0901s10. No abstract available.

PMID:
21971814
20.

Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

Kang J, Wang L, Chen XL, Triggle DJ, Rampe D.

Mol Pharmacol. 2001 Jan;59(1):122-6.

PMID:
11125032
21.

Receptor chemistry towards the third millennium.

Angeli P, Triggle DJ.

Farmaco. 2000 May;55(5):415-21. No abstract available.

PMID:
10983290
23.

Hijacked receptors.

Triggle DJ.

Pharm Acta Helv. 2000 Mar;74(2-3):287-90. Review.

PMID:
10812971
24.

Pharmacological receptors: a century of discovery--and more.

Triggle DJ.

Pharm Acta Helv. 2000 Mar;74(2-3):79-84. Review.

PMID:
10812943
25.

Receptor chemistry towards the third millennium.

Angeli P, Triggle DJ.

Farmaco. 2000 Jan;55(1):69-75. No abstract available. Corrected and republished in: Farmaco. 2000 May;55(5):415-21.

PMID:
10755235
26.

Lipophilic 4-isoxazolyl-1,4-dihydropyridines: synthesis and structure-activity relationships.

Natale NR, Rogers ME, Staples R, Triggle DJ, Rutledge A.

J Med Chem. 1999 Aug 12;42(16):3087-93.

PMID:
10447952
27.

The pharmacology of ion channels: with particular reference to voltage-gated Ca2+ channels.

Triggle DJ.

Eur J Pharmacol. 1999 Jun 30;375(1-3):311-25. Review.

PMID:
10443585
28.

Rho Chi lecture. Pharmaceutical sciences in the next millennium.

Triggle DJ.

Ann Pharmacother. 1999 Feb;33(2):241-6.

PMID:
10084422
29.
30.

Cardiovascular T-type calcium channels: physiological and pharmacological significance.

Triggle DJ.

J Hypertens Suppl. 1997 Dec;15(5):S9-15. Review.

PMID:
9481611
32.

Depolarization as a regulatory signal at voltage-gated calcium channels.

Triggle DJ.

Zhongguo Yao Li Xue Bao. 1996 May;17(3):193-6. Review.

33.
34.
35.

Angiotensin II receptor antagonism: losartan - sites and mechanisms of action.

Triggle DJ.

Clin Ther. 1995 Nov-Dec;17(6):1005-30. Review.

PMID:
8750395
36.
37.

Short-term regulation of neuronal calcium channels by depolarization.

Liu J, Rutledge A, Triggle DJ.

Ann N Y Acad Sci. 1995 Sep 15;765:119-33; discussion 160-2.

PMID:
7486600
38.

The binding interactions of Ro 40-5967 at the L-type Ca2+ channel in cardiac tissue.

Rutledge A, Triggle DJ.

Eur J Pharmacol. 1995 Jul 4;280(2):155-8.

PMID:
7589180
39.

Calcium channel antagonists: cardiovascular selectivity of action.

Sun J, Triggle DJ.

J Pharmacol Exp Ther. 1995 Jul;274(1):419-26.

PMID:
7616426
40.

Decreased dihydropyridine receptor number in hypertensive rat vascular muscle cells.

Hermsmeyer K, White AC, Triggle DJ.

Hypertension. 1995 Apr;25(4 Pt 2):731-4.

PMID:
7721424
41.

Molecular pharmacology of voltage-gated calcium channels.

Triggle DJ.

Ann N Y Acad Sci. 1994 Dec 15;747:267-81. Review. No abstract available.

PMID:
7847676
42.

Concepts and progress in the development and utilization of receptor-specific fluorescent ligands.

Baindur N, Triggle DJ.

Med Res Rev. 1994 Nov;14(6):591-664. Review. No abstract available.

PMID:
7530311
43.

L-type calcium channels: asymmetrical intramembrane binding domain revealed by variable length, permanently charged 1,4-dihydropyridines.

Bangalore R, Baindur N, Rutledge A, Triggle DJ, Kass RS.

Mol Pharmacol. 1994 Oct;46(4):660-6.

PMID:
7969044
44.

Modulation of L-type Ca2+ channels in clonal rat pituitary cells by membrane depolarization.

Liu J, Bangalore R, Rutledge A, Triggle DJ.

Mol Pharmacol. 1994 Jun;45(6):1198-206.

PMID:
8022413
45.

On the other hand: the stereoselectivity of drug action at ion channels.

Triggle DJ.

Chirality. 1994;6(2):58-62. Review.

PMID:
7515633
46.

A homologous series of permanently charged 1,4-dihydropyridines: novel probes designed to localize drug binding sites on ion channels.

Baindur N, Rutledge A, Triggle DJ.

J Med Chem. 1993 Nov 12;36(23):3743-5. No abstract available.

PMID:
8246246
47.

Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.

Bauer JA, Fung HL, Zheng W, Kwon YW, Gopalakrishnan M, Triggle DJ.

J Cardiovasc Pharmacol. 1993 Oct;22(4):600-8. Erratum in: J Cardiovasc Pharmacol 1994 Apr;23(4):690.

PMID:
7505363
48.

New synthetic ligands for L-type voltage-gated calcium channels.

Rampe D, Triggle DJ.

Prog Drug Res. 1993;40:191-238. Review.

PMID:
8395066
49.

Effect of an homologous series of aliphatic alcohols on neuronal and smooth muscle voltage-dependent Ca2+ channels.

Hawthorn MH, Ferrante JN, Kwon YW, Rutledge A, Luchowski E, Bangalore R, Triggle DJ.

Eur J Pharmacol. 1992 Dec 15;229(2-3):143-8.

PMID:
1337043
50.

Regulation of ATP-sensitive K+ channels by chronic glyburide and pinacidil administration.

Gopalakrishnan M, Triggle DJ.

Biochem Pharmacol. 1992 Nov 3;44(9):1843-7.

PMID:
1333209

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