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Items: 1 to 50 of 84

1.

The generation of T-cell memory to protect against tuberculosis.

Counoupas C, Triccas JA.

Immunol Cell Biol. 2019 May 25. doi: 10.1111/imcb.12275. [Epub ahead of print] Review.

PMID:
31127962
2.

Deciphering protective immunity against tuberculosis: implications for vaccine development.

Counoupas C, Triccas JA, Britton WJ.

Expert Rev Vaccines. 2019 Apr;18(4):353-364. doi: 10.1080/14760584.2019.1585246. Epub 2019 Mar 4.

PMID:
30793629
3.

Pulmonary immunization with a recombinant influenza A virus vaccine induces lung-resident CD4+ memory T cells that are associated with protection against tuberculosis.

Flórido M, Muflihah H, Lin LCW, Xia Y, Sierro F, Palendira M, Feng CG, Bertolino P, Stambas J, Triccas JA, Britton WJ.

Mucosal Immunol. 2018 Nov;11(6):1743-1752. doi: 10.1038/s41385-018-0065-9. Epub 2018 Aug 16.

PMID:
30115996
4.

Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance.

Chellan P, Avery VM, Duffy S, Triccas JA, Nagalingam G, Tam C, Cheng LW, Liu J, Land KM, Clarkson GJ, Romero-Canelón I, Sadler PJ.

Chemistry. 2018 Apr 13. doi: 10.1002/chem.201801090. [Epub ahead of print]

PMID:
29653033
5.

Protective efficacy of recombinant BCG over-expressing protective, stage-specific antigens of Mycobacterium tuberculosis.

Counoupas C, Pinto R, Nagalingam G, Britton WJ, Triccas JA.

Vaccine. 2018 May 3;36(19):2619-2629. doi: 10.1016/j.vaccine.2018.03.066. Epub 2018 Apr 5.

PMID:
29627232
6.

Sequential pulmonary immunization with heterologous recombinant influenza A virus tuberculosis vaccines protects against murine M. tuberculosis infection.

Muflihah H, Flórido M, Lin LCW, Xia Y, Triccas JA, Stambas J, Britton WJ.

Vaccine. 2018 Apr 25;36(18):2462-2470. doi: 10.1016/j.vaccine.2018.03.037. Epub 2018 Mar 27.

PMID:
29602704
7.

Antitubercular Bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and in Vivo Studies.

Spain M, Wong JK, Nagalingam G, Batten JM, Hortle E, Oehlers SH, Jiang XF, Murage HE, Orford JT, Crisologo P, Triccas JA, Rutledge PJ, Todd MH.

J Med Chem. 2018 Apr 26;61(8):3595-3608. doi: 10.1021/acs.jmedchem.7b01569. Epub 2018 Apr 5.

PMID:
29558124
8.

A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans.

Zhang G, deWeerd NA, Stifter SA, Liu L, Zhou B, Wang W, Zhou Y, Ying B, Hu X, Matthews AY, Ellis M, Triccas JA, Hertzog PJ, Britton WJ, Chen X, Feng CG.

Nat Commun. 2018 Jan 8;9(1):85. doi: 10.1038/s41467-017-02611-z.

9.

Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens.

Nguyen N, Wilson DW, Nagalingam G, Triccas JA, Schneider EK, Li J, Velkov T, Baell J.

Eur J Med Chem. 2018 Mar 25;148:507-518. doi: 10.1016/j.ejmech.2017.10.010. Epub 2017 Oct 6.

PMID:
29269132
10.

Delta inulin-based adjuvants promote the generation of polyfunctional CD4+ T cell responses and protection against Mycobacterium tuberculosis infection.

Counoupas C, Pinto R, Nagalingam G, Britton WJ, Petrovsky N, Triccas JA.

Sci Rep. 2017 Aug 17;7(1):8582. doi: 10.1038/s41598-017-09119-y.

11.

Novel vaccination approaches to prevent tuberculosis in children.

Triccas JA, Counoupas C.

Pneumonia (Nathan). 2016 Nov 24;8:18. doi: 10.1186/s41479-016-0020-z. eCollection 2016. Review.

12.

New tuberculosis drug leads from naturally occurring compounds.

Quan D, Nagalingam G, Payne R, Triccas JA.

Int J Infect Dis. 2017 Mar;56:212-220. doi: 10.1016/j.ijid.2016.12.024. Epub 2017 Jan 3. Review.

13.

Mycobacterium tuberculosis components expressed during chronic infection of the lung contribute to long-term control of pulmonary tuberculosis in mice.

Counoupas C, Pinto R, Nagalingam G, Hill-Cawthorne GA, Feng CG, Britton WJ, Triccas JA.

NPJ Vaccines. 2016 Sep 15;1:16012. doi: 10.1038/npjvaccines.2016.12. eCollection 2016.

14.

Influence of phthiocerol dimycocerosate on CD4(+) T cell priming and persistence during Mycobacterium tuberculosis infection.

Pinto R, Nambiar JK, Leotta L, Counoupas C, Britton WJ, Triccas JA.

Tuberculosis (Edinb). 2016 Jul;99:25-30. doi: 10.1016/j.tube.2016.04.001. Epub 2016 Apr 4.

PMID:
27450001
15.

In vitro evaluation of novel inhalable dry powders consisting of thioridazine and rifapentine for rapid tuberculosis treatment.

Parumasivam T, Chan JG, Pang A, Quan DH, Triccas JA, Britton WJ, Chan HK.

Eur J Pharm Biopharm. 2016 Oct;107:205-14. doi: 10.1016/j.ejpb.2016.07.014. Epub 2016 Jul 12.

PMID:
27422209
16.

Development and delivery of anti-tuberculosis drugs, vaccines and immunotherapeutics.

Triccas JA, Feng CG.

Adv Drug Deliv Rev. 2016 Jul 1;102:1-2. doi: 10.1016/j.addr.2016.05.017. No abstract available.

PMID:
27288546
17.

Nontoxic Metal-Cyclam Complexes, a New Class of Compounds with Potency against Drug-Resistant Mycobacterium tuberculosis.

Yu M, Nagalingam G, Ellis S, Martinez E, Sintchenko V, Spain M, Rutledge PJ, Todd MH, Triccas JA.

J Med Chem. 2016 Jun 23;59(12):5917-21. doi: 10.1021/acs.jmedchem.6b00432. Epub 2016 Jun 7.

PMID:
27214150
18.

The Ag85B protein of the BCG vaccine facilitates macrophage uptake but is dispensable for protection against aerosol Mycobacterium tuberculosis infection.

Prendergast KA, Counoupas C, Leotta L, Eto C, Bitter W, Winter N, Triccas JA.

Vaccine. 2016 May 17;34(23):2608-15. doi: 10.1016/j.vaccine.2016.03.089. Epub 2016 Apr 6.

PMID:
27060378
19.

Rifapentine-loaded PLGA microparticles for tuberculosis inhaled therapy: Preparation and in vitro aerosol characterization.

Parumasivam T, Leung SS, Quan DH, Triccas JA, Britton WJ, Chan HK.

Eur J Pharm Sci. 2016 Jun 10;88:1-11. doi: 10.1016/j.ejps.2016.03.024. Epub 2016 Apr 2.

PMID:
27049049
20.

In Vitro Evaluation of Inhalable Verapamil-Rifapentine Particles for Tuberculosis Therapy.

Parumasivam T, Chan JG, Pang A, Quan DH, Triccas JA, Britton WJ, Chan HK.

Mol Pharm. 2016 Mar 7;13(3):979-89. doi: 10.1021/acs.molpharmaceut.5b00833. Epub 2016 Feb 12.

PMID:
26808409
21.

Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation.

Stifter SA, Bhattacharyya N, Pillay R, Flórido M, Triccas JA, Britton WJ, Feng CG.

PLoS Pathog. 2016 Jan 5;12(1):e1005378. doi: 10.1371/journal.ppat.1005378. eCollection 2016 Jan.

22.

Homogentisate 1-2-Dioxygenase Downregulation in the Chronic Persistence of Pseudomonas aeruginosa Australian Epidemic Strain-1 in the CF Lung.

Harmer CJ, Wynn M, Pinto R, Cordwell S, Rose BR, Harbour C, Triccas JA, Manos J.

PLoS One. 2015 Aug 7;10(8):e0134229. doi: 10.1371/journal.pone.0134229. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0138633.

23.

An inducible expression system for high-level expression of recombinant proteins in slow growing mycobacteria.

Leotta L, Spratt JM, Kong CU, Triccas JA.

Plasmid. 2015 Sep;81:27-31. doi: 10.1016/j.plasmid.2015.05.002. Epub 2015 May 27.

PMID:
26021569
24.

Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in Open Science.

Badiola KA, Quan DH, Triccas JA, Todd MH.

PLoS One. 2014 Dec 10;9(12):e111782. doi: 10.1371/journal.pone.0111782. eCollection 2014.

25.

Epitope-specific CD4+, but not CD8+, T-cell responses induced by recombinant influenza A viruses protect against Mycobacterium tuberculosis infection.

Flórido M, Pillay R, Gillis CM, Xia Y, Turner SJ, Triccas JA, Stambas J, Britton WJ.

Eur J Immunol. 2015 Mar;45(3):780-93. doi: 10.1002/eji.201444954. Epub 2014 Dec 23.

26.

Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β.

Yu M, Ryan TM, Ellis S, Bush AI, Triccas JA, Rutledge PJ, Todd MH.

Metallomics. 2014 Oct;6(10):1931-40. doi: 10.1039/c4mt00122b. Epub 2014 Aug 18.

PMID:
25132118
27.

Incorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity.

Yu M, Lim NH, Ellis S, Nagase H, Triccas JA, Rutledge PJ, Todd MH.

ChemistryOpen. 2013 Jun;2(3):99-105. doi: 10.1002/open.201300014. Epub 2013 Jun 12.

28.

Potent antimycobacterial activity of the pyridoxal isonicotinoyl hydrazone analog 2-pyridylcarboxaldehyde isonicotinoyl hydrazone: a lipophilic transport vehicle for isonicotinic acid hydrazide.

Ellis S, Kalinowski DS, Leotta L, Huang ML, Jelfs P, Sintchenko V, Richardson DR, Triccas JA.

Mol Pharmacol. 2014 Feb;85(2):269-78. doi: 10.1124/mol.113.090357. Epub 2013 Nov 15.

29.

Modulation of gene expression by Pseudomonas aeruginosa during chronic infection in the adult cystic fibrosis lung.

Harmer C, Alnassafi K, Hu H, Elkins M, Bye P, Rose B, Cordwell S, Triccas JA, Harbour C, Manos J.

Microbiology. 2013 Nov;159(Pt 11):2354-63. doi: 10.1099/mic.0.066985-0. Epub 2013 Sep 6.

PMID:
24014664
30.

Influenza A virus infection impairs mycobacteria-specific T cell responses and mycobacterial clearance in the lung during pulmonary coinfection.

Flórido M, Grima MA, Gillis CM, Xia Y, Turner SJ, Triccas JA, Stambas J, Britton WJ.

J Immunol. 2013 Jul 1;191(1):302-11. doi: 10.4049/jimmunol.1202824. Epub 2013 May 22.

31.

Harnessing single cell sorting to identify cell division genes and regulators in bacteria.

Burke C, Liu M, Britton W, Triccas JA, Thomas T, Smith AL, Allen S, Salomon R, Harry E.

PLoS One. 2013;8(4):e60964. doi: 10.1371/journal.pone.0060964. Epub 2013 Apr 2.

32.

Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis.

Pinto R, Leotta L, Shanahan ER, West NP, Leyh TS, Britton W, Triccas JA.

J Infect Dis. 2013 Mar 1;207(5):778-85. doi: 10.1093/infdis/jis751. Epub 2012 Dec 7.

33.

The secreted lipoprotein, MPT83, of Mycobacterium tuberculosis is recognized during human tuberculosis and stimulates protective immunity in mice.

Kao FF, Mahmuda S, Pinto R, Triccas JA, West NP, Britton WJ.

PLoS One. 2012;7(5):e34991. doi: 10.1371/journal.pone.0034991. Epub 2012 May 2.

34.

Two lymph nodes draining the mouse liver are the preferential site of DC migration and T cell activation.

Barbier L, Tay SS, McGuffog C, Triccas JA, McCaughan GW, Bowen DG, Bertolino P.

J Hepatol. 2012 Aug;57(2):352-8. doi: 10.1016/j.jhep.2012.03.023. Epub 2012 Apr 25.

PMID:
22542491
35.

Pseudomonas aeruginosa strains from the chronically infected cystic fibrosis lung display increased invasiveness of A549 epithelial cells over time.

Harmer CJ, Triccas JA, Hu H, Rose B, Bye P, Elkins M, Manos J.

Microb Pathog. 2012 Jul;53(1):37-43. doi: 10.1016/j.micpath.2012.03.011. Epub 2012 Apr 10.

PMID:
22516803
36.

Protective immunity afforded by attenuated, PhoP-deficient Mycobacterium tuberculosis is associated with sustained generation of CD4+ T-cell memory.

Nambiar JK, Pinto R, Aguilo JI, Takatsu K, Martin C, Britton WJ, Triccas JA.

Eur J Immunol. 2012 Feb;42(2):385-92. doi: 10.1002/eji.201141903. Epub 2011 Dec 27.

37.

Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosis.

West NP, Thomson SA, Triccas JA, Medveczky CJ, Ramshaw IA, Britton WJ.

Vaccine. 2011 Oct 13;29(44):7759-65. doi: 10.1016/j.vaccine.2011.07.109. Epub 2011 Aug 16.

PMID:
21846485
38.

Cutaneous immunosurveillance by self-renewing dermal gammadelta T cells.

Sumaria N, Roediger B, Ng LG, Qin J, Pinto R, Cavanagh LL, Shklovskaya E, Fazekas de St Groth B, Triccas JA, Weninger W.

J Exp Med. 2011 Mar 14;208(3):505-18. doi: 10.1084/jem.20101824. Epub 2011 Feb 21.

39.

In vivo persistence and protective efficacy of the bacille Calmette Guerin vaccine overexpressing the HspX latency antigen.

Spratt JM, Britton WJ, Triccas JA.

Bioeng Bugs. 2010 Jan-Feb;1(1):61-5. doi: 10.4161/bbug.1.1.10027.

40.

Recombinant BCG as a vaccine vehicle to protect against tuberculosis.

Triccas JA.

Bioeng Bugs. 2010 Mar-Apr;1(2):110-5. doi: 10.4161/bbug.1.2.10483. Epub 2009 Nov 2. Review.

41.

Targeted induction of antigen expression within dendritic cells modulates antigen-specific immunity afforded by recombinant BCG.

Kong CU, Ng LG, Nambiar JK, Spratt JM, Weninger W, Triccas JA.

Vaccine. 2011 Feb 4;29(7):1374-81. doi: 10.1016/j.vaccine.2010.12.070. Epub 2011 Jan 4.

PMID:
21211591
42.

Leads for antitubercular compounds from kinase inhibitor library screens.

Magnet S, Hartkoorn RC, Székely R, Pató J, Triccas JA, Schneider P, Szántai-Kis C, Orfi L, Chambon M, Banfi D, Bueno M, Turcatti G, Kéri G, Cole ST.

Tuberculosis (Edinb). 2010 Nov;90(6):354-60. doi: 10.1016/j.tube.2010.09.001. Epub 2010 Oct 8.

PMID:
20934382
43.

The same well-characterized T cell epitope SIINFEKL expressed in the context of a cytoplasmic or secreted protein in BCG induces different CD8+ T cell responses.

Hulseberg PD, Zozulya A, Chu HH, Triccas JA, Fabry Z, Sandor M.

Immunol Lett. 2010 May 4;130(1-2):36-42. doi: 10.1016/j.imlet.2009.12.004. Epub 2009 Dec 11.

44.

Cutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccine.

Shanahan ER, Pinto R, Triccas JA, Britton WJ, West NP.

Vaccine. 2010 Feb 3;28(5):1341-6. doi: 10.1016/j.vaccine.2009.11.010. Epub 2009 Nov 24.

PMID:
19941992
45.

Modulation of pulmonary DC function by vaccine-encoded GM-CSF enhances protective immunity against Mycobacterium tuberculosis infection.

Nambiar JK, Ryan AA, Kong CU, Britton WJ, Triccas JA.

Eur J Immunol. 2010 Jan;40(1):153-61. doi: 10.1002/eji.200939665.

46.

Challenge of developing new tuberculosis vaccines to generate life-long protective immunity.

Triccas JA, Nambiar JK.

Expert Rev Vaccines. 2009 Jul;8(7):823-5. doi: 10.1586/erv.09.50. No abstract available.

PMID:
19538108
47.

Antigen load governs the differential priming of CD8 T cells in response to the bacille Calmette Guerin vaccine or Mycobacterium tuberculosis infection.

Ryan AA, Nambiar JK, Wozniak TM, Roediger B, Shklovskaya E, Britton WJ, Fazekas de St Groth B, Triccas JA.

J Immunol. 2009 Jun 1;182(11):7172-7. doi: 10.4049/jimmunol.0801694.

48.

Heterologous expression of genes in mycobacteria.

Triccas JA, Ryan AA.

Methods Mol Biol. 2009;465:243-53. doi: 10.1007/978-1-59745-207-6_16.

PMID:
20560073
49.

Migratory dermal dendritic cells act as rapid sensors of protozoan parasites.

Ng LG, Hsu A, Mandell MA, Roediger B, Hoeller C, Mrass P, Iparraguirre A, Cavanagh LL, Triccas JA, Beverley SM, Scott P, Weninger W.

PLoS Pathog. 2008 Nov;4(11):e1000222. doi: 10.1371/journal.ppat.1000222. Epub 2008 Nov 28.

50.

Infectious diseases: too little, too late for tuberculosis.

Triccas JA, Davenport MP.

Immunol Cell Biol. 2008 May-Jun;86(4):293-4. doi: 10.1038/icb.2008.7. Epub 2008 Mar 11. No abstract available.

PMID:
18332895

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