Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 84


Dendritic Cells Promote the Spread of Human T-Cell Leukemia Virus Type 1 via Bidirectional Interactions with CD4+ T Cells.

Shimauchi T, Caucheteux S, Finsterbusch K, Turpin J, Blanchet F, Ladell K, Triantafilou K, Czubala M, Tatsuno K, Easter T, Ahmed Z, Bayliss R, Hakobyan S, Price DA, Tokura Y, Piguet V.

J Invest Dermatol. 2019 Jan;139(1):157-166. doi: 10.1016/j.jid.2018.06.188. Epub 2018 Jul 23.


An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.

Carroll RG, Zasłona Z, Galván-Peña S, Koppe EL, Sévin DC, Angiari S, Triantafilou M, Triantafilou K, Modis LK, O'Neill LA.

J Biol Chem. 2018 Apr 13;293(15):5509-5521. doi: 10.1074/jbc.RA118.001921. Epub 2018 Feb 20.


Inflammasome Priming in Sterile Inflammatory Disease.

Patel MN, Carroll RG, Galván-Peña S, Mills EL, Olden R, Triantafilou M, Wolf AI, Bryant CE, Triantafilou K, Masters SL.

Trends Mol Med. 2017 Feb;23(2):165-180. doi: 10.1016/j.molmed.2016.12.007. Epub 2017 Jan 18. Review.


Complementing the inflammasome.

Triantafilou M, Hughes TR, Morgan BP, Triantafilou K.

Immunology. 2016 Feb;147(2):152-64. doi: 10.1111/imm.12556. Review.


Ion flux in the lung: virus-induced inflammasome activation.

Triantafilou K, Triantafilou M.

Trends Microbiol. 2014 Oct;22(10):580-8. doi: 10.1016/j.tim.2014.06.002. Epub 2014 Jun 29.


Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis.

Maekawa T, Krauss JL, Abe T, Jotwani R, Triantafilou M, Triantafilou K, Hashim A, Hoch S, Curtis MA, Nussbaum G, Lambris JD, Hajishengallis G.

Cell Host Microbe. 2014 Jun 11;15(6):768-78. doi: 10.1016/j.chom.2014.05.012.


Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering.

Shang L, Daubeuf B, Triantafilou M, Olden R, Dépis F, Raby AC, Herren S, Dos Santos A, Malinge P, Dunn-Siegrist I, Benmkaddem S, Geinoz A, Magistrelli G, Rousseau F, Buatois V, Salgado-Pires S, Reith W, Monteiro R, Pugin J, Leger O, Ferlin W, Kosco-Vilbois M, Triantafilou K, Elson G.

J Biol Chem. 2014 May 30;289(22):15309-18. doi: 10.1074/jbc.M113.537936. Epub 2014 Apr 15.


Herpes simplex virus 2-induced activation in vaginal cells involves Toll-like receptors 2 and 9 and DNA sensors DAI and IFI16.

Triantafilou K, Eryilmazlar D, Triantafilou M.

Am J Obstet Gynecol. 2014 Feb;210(2):122.e1-122.e10. doi: 10.1016/j.ajog.2013.09.034. Epub 2013 Sep 28.


Correction: Synergic Activation of Toll-Like Receptor (TLR) 2/6 and 9 in Response to Ureaplasma parvum & urealyticum in Human Amniotic Epithelial Cells.

Triantafilou M, De Glanville B, Aboklaish AF, Spiller OB, Kotecha S, Triantafilou K.

PLoS One. 2013 Aug 21;8(8). doi: 10.1371/annotation/1dc00176-e096-4621-9494-2d848dac8262. eCollection 2013.


Rhinovirus-induced calcium flux triggers NLRP3 and NLRC5 activation in bronchial cells.

Triantafilou K, Kar S, van Kuppeveld FJ, Triantafilou M.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):923-34. doi: 10.1165/rcmb.2013-0032OC.


The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation.

Triantafilou K, Hughes TR, Triantafilou M, Morgan BP.

J Cell Sci. 2013 Jul 1;126(Pt 13):2903-13. doi: 10.1242/jcs.124388. Epub 2013 Apr 23.


Synergic activation of toll-like receptor (TLR) 2/6 and 9 in response to Ureaplasma parvum & urealyticum in human amniotic epithelial cells.

Triantafilou M, De Glanville B, Aboklaish AF, Spiller OB, Kotecha S, Triantafilou K.

PLoS One. 2013 Apr 12;8(4):e61199. doi: 10.1371/journal.pone.0061199. Print 2013. Erratum in: PLoS One. 2013 Aug 21;8(8):null.


Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation.

Triantafilou K, Kar S, Vakakis E, Kotecha S, Triantafilou M.

Thorax. 2013 Jan;68(1):66-75. doi: 10.1136/thoraxjnl-2012-202182.


Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses.

Triantafilou K, Vakakis E, Kar S, Richer E, Evans GL, Triantafilou M.

J Cell Sci. 2012 Oct 15;125(Pt 20):4761-9. doi: 10.1242/jcs.103887. Epub 2012 Jul 13.


Serum proteins modulate lipopolysaccharide and lipoteichoic acid-induced activation and contribute to the clinical outcome of sepsis.

Triantafilou M, Mouratis MA, Lepper PM, Haston RM, Baldwin F, Lowes S, Ahmed MA, Schumann C, Boyd O, Triantafilou K.

Virulence. 2012 Mar-Apr;3(2):136-45. doi: 10.4161/viru.19077. Epub 2012 Mar 1.


MARCKS as a negative regulator of lipopolysaccharide signaling.

Mancek-Keber M, Bencina M, Japelj B, Panter G, Andrä J, Brandenburg K, Triantafilou M, Triantafilou K, Jerala R.

J Immunol. 2012 Apr 15;188(8):3893-902. doi: 10.4049/jimmunol.1003605. Epub 2012 Mar 16.


Visualising PAMP-PRR interactions using nanoscale imaging.

Triantafilou K, Triantafilou M.

Methods Mol Biol. 2012;799:253-66. doi: 10.1007/978-1-61779-346-2_16.


Location, location, location: is membrane partitioning everything when it comes to innate immune activation?

Triantafilou M, Lepper PM, Olden R, Dias IS, Triantafilou K.

Mediators Inflamm. 2011;2011:186093. doi: 10.1155/2011/186093. Epub 2011 Jun 21. Review.


Modulation of toll-like receptor signalling as a new therapeutic principle.

Lepper PM, Triantafilou M, O'Neill LA, Novak N, Wagner H, Parker AE, Triantafilou K.

Mediators Inflamm. 2010;2010:705612. doi: 10.1155/2010/705612. Epub 2011 Jan 2. No abstract available.


Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response.

Triantafilou K, Vakakis E, Richer EA, Evans GL, Villiers JP, Triantafilou M.

Virulence. 2011 Jan-Feb;2(1):22-9. Epub 2011 Jan 1.


Internalization and coreceptor expression are critical for TLR2-mediated recognition of lipoteichoic acid in human peripheral blood.

Bunk S, Sigel S, Metzdorf D, Sharif O, Triantafilou K, Triantafilou M, Hartung T, Knapp S, von Aulock S.

J Immunol. 2010 Sep 15;185(6):3708-17. doi: 10.4049/jimmunol.0901660. Epub 2010 Aug 16.


Membrane partitioning: is location everything when it comes to endotoxin recognition?

Triantafilou M, Triantafilou K.

Subcell Biochem. 2010;53:173-84. doi: 10.1007/978-90-481-9078-2_8. Review.


Microbial hijacking of complement-toll-like receptor crosstalk.

Wang M, Krauss JL, Domon H, Hosur KB, Liang S, Magotti P, Triantafilou M, Triantafilou K, Lambris JD, Hajishengallis G.

Sci Signal. 2010 Feb 16;3(109):ra11. doi: 10.1126/scisignal.2000697.


Host adhesive activities and virulence of novel fimbrial proteins of Porphyromonas gingivalis.

Pierce DL, Nishiyama S, Liang S, Wang M, Triantafilou M, Triantafilou K, Yoshimura F, Demuth DR, Hajishengallis G.

Infect Immun. 2009 Aug;77(8):3294-301. doi: 10.1128/IAI.00262-09. Epub 2009 Jun 8.


A phosphatidylserine species inhibits a range of TLR- but not IL-1beta-induced inflammatory responses by disruption of membrane microdomains.

Parker LC, Prestwich EC, Ward JR, Smythe E, Berry A, Triantafilou M, Triantafilou K, Sabroe I.

J Immunol. 2008 Oct 15;181(8):5606-17.


Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function.

Hajishengallis G, Wang M, Liang S, Triantafilou M, Triantafilou K.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13532-7. doi: 10.1073/pnas.0803852105. Epub 2008 Sep 2.


Cell surface molecular chaperones as endogenous modulators of the innate immune response.

Triantafilou M, Sawyer D, Nor A, Vakakis E, Triantafilou K.

Novartis Found Symp. 2008;291:74-9; discussion 79-85, 137-40.


In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat.

Culty M, Thuillier R, Li W, Wang Y, Martinez-Arguelles DB, Benjamin CG, Triantafilou KM, Zirkin BR, Papadopoulos V.

Biol Reprod. 2008 Jun;78(6):1018-28. doi: 10.1095/biolreprod.107.065649. Epub 2008 Mar 5.


Chemokine receptor 4 (CXCR4) is part of the lipopolysaccharide "sensing apparatus".

Triantafilou M, Lepper PM, Briault CD, Ahmed MA, Dmochowski JM, Schumann C, Triantafilou K.

Eur J Immunol. 2008 Jan;38(1):192-203.


Anthrax toxin evades Toll-like receptor recognition, whereas its cell wall components trigger activation via TLR2/6 heterodimers.

Triantafilou M, Uddin A, Maher S, Charalambous N, Hamm TS, Alsumaiti A, Triantafilou K.

Cell Microbiol. 2007 Dec;9(12):2880-92. Epub 2007 Jul 26.


Association of lipopolysaccharide-binding protein and coronary artery disease in men.

Lepper PM, Schumann C, Triantafilou K, Rasche FM, Schuster T, Frank H, Schneider EM, Triantafilou M, von Eynatten M.

J Am Coll Cardiol. 2007 Jul 3;50(1):25-31. Epub 2007 Jun 18.


Toll-like receptor polymorphisms and carotid artery intima-media thickness.

Lepper PM, von Eynatten M, Humpert PM, Triantafilou M, Triantafilou K.

Stroke. 2007 Jul;38(7):e50. Epub 2007 May 17. No abstract available.


Lipopolysaccharides from atherosclerosis-associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2-induced inflammatory responses in human vascular endothelial cells.

Triantafilou M, Gamper FG, Lepper PM, Mouratis MA, Schumann C, Harokopakis E, Schifferle RE, Hajishengallis G, Triantafilou K.

Cell Microbiol. 2007 Aug;9(8):2030-9. Epub 2007 Apr 5.


The A subunit of type IIb enterotoxin (LT-IIb) suppresses the proinflammatory potential of the B subunit and its ability to recruit and interact with TLR2.

Liang S, Wang M, Triantafilou K, Triantafilou M, Nawar HF, Russell MW, Connell TD, Hajishengallis G.

J Immunol. 2007 Apr 15;178(8):4811-9.


Detection of erythropoietin in exhaled breath condensate of nonhypoxic subjects using a multiplex bead array.

Schumann C, Triantafilou K, Krueger S, Hombach V, Triantafilou M, Becher G, Lepper PM.

Mediators Inflamm. 2006;2006(5):18061.


Ganglioside GD1a is an essential coreceptor for Toll-like receptor 2 signaling in response to the B subunit of type IIb enterotoxin.

Liang S, Wang M, Tapping RI, Stepensky V, Nawar HF, Triantafilou M, Triantafilou K, Connell TD, Hajishengallis G.

J Biol Chem. 2007 Mar 9;282(10):7532-42. Epub 2007 Jan 16.


Porphyromonas gingivalis fimbriae proactively modulate beta2 integrin adhesive activity and promote binding to and internalization by macrophages.

Hajishengallis G, Wang M, Harokopakis E, Triantafilou M, Triantafilou K.

Infect Immun. 2006 Oct;74(10):5658-66.


Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus.

Hajishengallis G, Tapping RI, Harokopakis E, Nishiyama S, Ratti P, Schifferle RE, Lyle EA, Triantafilou M, Triantafilou K, Yoshimura F.

Cell Microbiol. 2006 Oct;8(10):1557-70.


Innate recognition of bacteria: potential therapeutic targets for bacterial sepsis.

Triantafilou K, Triantafilou M.

Expert Rev Clin Immunol. 2006 Sep;2(5):787-99. doi: 10.1586/1744666X.2.5.787.


Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting.

Triantafilou M, Gamper FG, Haston RM, Mouratis MA, Morath S, Hartung T, Triantafilou K.

J Biol Chem. 2006 Oct 13;281(41):31002-11. Epub 2006 Jul 31.


Serum antibody positivity for distinct Helicobacter pylori antigens in benign and malignant gastroduodenal disease.

Schumann C, Triantafilou K, Rasche FM, Möricke A, Vogt K, Triantafilou M, Hahn P, Schneider EM, Lepper PM.

Int J Med Microbiol. 2006 Aug;296(4-5):223-8.


Septic shock caused by Streptococcus pneumoniae in a post-splenectomy patient successfully treated with recombinant human activated protein C.

Schumann C, Triantafilou K, Kamenz J, Hanke H, Triantafilou M, Wittemann S, Joos T, Hombach V, Schneider EM, Lepper PM.

Scand J Infect Dis. 2006;38(2):139-42.


TLR8 and TLR7 are involved in the host's immune response to human parechovirus 1.

Triantafilou K, Vakakis E, Orthopoulos G, Ahmed MA, Schumann C, Lepper PM, Triantafilou M.

Eur J Immunol. 2005 Aug;35(8):2416-23.


Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent.

Triantafilou K, Orthopoulos G, Vakakis E, Ahmed MA, Golenbock DT, Lepper PM, Triantafilou M.

Cell Microbiol. 2005 Aug;7(8):1117-26.


The dynamics of LPS recognition: complex orchestration of multiple receptors.

Triantafilou M, Triantafilou K.

J Endotoxin Res. 2005;11(1):5-11. Review.


Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4.

Lepper PM, Triantafilou M, Schumann C, Schneider EM, Triantafilou K.

Cell Microbiol. 2005 Apr;7(4):519-28.


Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1.

Manukyan M, Triantafilou K, Triantafilou M, Mackie A, Nilsen N, Espevik T, Wiesmüller KH, Ulmer AJ, Heine H.

Eur J Immunol. 2005 Mar;35(3):911-21.


Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling.

Humphries HE, Triantafilou M, Makepeace BL, Heckels JE, Triantafilou K, Christodoulides M.

Cell Microbiol. 2005 Mar;7(3):415-30.


Coxsackie B viruses use multiple receptors to infect human cardiac cells.

Orthopoulos G, Triantafilou K, Triantafilou M.

J Med Virol. 2004 Oct;74(2):291-9.


Supplemental Content

Loading ...
Support Center