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Items: 1 to 50 of 71

1.

Central nervous system effects of intrathecal muscle relaxants in rats.

Szenohradszky J, Trevor AJ, Bickler P, Caldwell JE, Sharma ML, Rampil IJ, Miller RD.

Anesth Analg. 1993 Jun;76(6):1304-9.

PMID:
8098920
2.

In vivo intracerebral microdialysis studies in rats of MPP+ analogues and related charged species.

Rollema H, Johnson EA, Booth RG, Caldera P, Lampen P, Youngster SK, Trevor AJ, Naiman N, Castagnoli N Jr.

J Med Chem. 1990 Aug;33(8):2221-30.

PMID:
2374149
3.

Liver and lung microsomal metabolism of the tobacco alkaloid beta-nicotyrine.

Shigenaga MK, Kim BH, Caldera-Munoz P, Cairns T, Jacob P 3rd, Trevor AJ, Castagnoli N Jr.

Chem Res Toxicol. 1989 Sep-Oct;2(5):282-7.

PMID:
2519819
4.

1-methyl-4-phenylpyridinium (MPP+) analogs: in vivo neurotoxicity and inhibition of striatal synaptosomal dopamine uptake.

Johnson EA, Wu EY, Rollema H, Booth RG, Trevor AJ, Castagnoli N Jr.

Eur J Pharmacol. 1989 Jul 4;166(1):65-74.

PMID:
2806366
5.

Effect of etomidate on hepatic drug metabolism in humans.

Atiba JO, Horai Y, White PF, Trevor AJ, Blaschke TF, Sung ML.

Anesthesiology. 1988 Jun;68(6):920-4.

PMID:
3377236
6.
7.

Metabolism-dependent covalent binding of (S)-[5-3H]nicotine to liver and lung microsomal macromolecules.

Shigenaga MK, Trevor AJ, Castagnoli N Jr.

Drug Metab Dispos. 1988 May-Jun;16(3):397-402.

PMID:
2900731
9.

Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Singer TP, Castagnoli N Jr, Ramsay RR, Trevor AJ.

J Neurochem. 1987 Jul;49(1):1-8. No abstract available.

PMID:
3495634
10.

Phencyclidine iminium ion. NADPH-dependent metabolism, covalent binding to macromolecules, and inactivation of cytochrome(s) P-450.

Hoag MK, Trevor AJ, Kalir A, Castagnoli N Jr.

Drug Metab Dispos. 1987 Jul-Aug;15(4):485-90.

PMID:
2888621
11.

Pharmacodynamic modeling of the EEG effects of ketamine and its enantiomers in man.

Schüttler J, Stanski DR, White PF, Trevor AJ, Horai Y, Verotta D, Sheiner LB.

J Pharmacokinet Biopharm. 1987 Jun;15(3):241-53.

PMID:
3668802
12.

Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae.

Trevor AJ, Castagnoli N Jr, Caldera P, Ramsay RR, Singer TP.

Life Sci. 1987 Feb 23;40(8):713-9.

PMID:
3492651
13.

Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes.

Di Monte D, Ekström G, Shinka T, Smith MT, Trevor AJ, Castagnoli N Jr.

Chem Biol Interact. 1987;62(2):105-16.

PMID:
3496169
14.

Processing of MPTP by monoamine oxidases: implications for molecular toxicology.

Trevor AJ, Singer TP, Ramsay RR, Castagnoli N Jr.

J Neural Transm Suppl. 1987;23:73-89. Review.

PMID:
3295117
15.

Interactions of the 1-methyl-4-phenyl-2,3-dihydropyridinium species with synthetic dopamine-melanin.

Wu EY, Chiba K, Trevor AJ, Castagnoli N Jr.

Life Sci. 1986 Nov 3;39(18):1695-700.

PMID:
3490611
16.

Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.

Chiba K, Trevor AJ, Castagnoli N Jr.

Biochem Biophys Res Commun. 1985 May 16;128(3):1228-32.

PMID:
3873939
17.

The effect of etomidate on rabbit liver microsomal drug metabolism in vitro.

Horai Y, White PF, Trevor AJ.

Drug Metab Dispos. 1985 May-Jun;13(3):364-7.

PMID:
2861997
18.

Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Chiba K, Peterson LA, Castagnoli KP, Trevor AJ, Castagnoli N Jr.

Drug Metab Dispos. 1985 May-Jun;13(3):342-7.

PMID:
2861994
19.

Comparative pharmacology of the ketamine isomers. Studies in volunteers.

White PF, Schüttler J, Shafer A, Stanski DR, Horai Y, Trevor AJ.

Br J Anaesth. 1985 Feb;57(2):197-203.

20.

Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

Castagnoli N Jr, Chiba K, Trevor AJ.

Life Sci. 1985 Jan 21;36(3):225-30.

PMID:
3871243
21.

Metabolism-dependent inactivation of liver microsomal enzymes by phencyclidine.

Hoag MK, Trevor AJ, Asscher Y, Weissman J, Castagnoli N Jr.

Drug Metab Dispos. 1984 May-Jun;12(3):371-5.

PMID:
6145566
22.

Comparison of continuous infusion fentanyl or ketamine versus thiopental--determining the mean effective serum concentrations for outpatient surgery.

White PF, Dworsky WA, Horai Y, Trevor AJ.

Anesthesiology. 1983 Dec;59(6):564-9. No abstract available.

PMID:
6650914
23.

Ketamine, catecholamines, and uterine tone in pregnant ewes.

Craft JB Jr, Coaldrake LA, Yonekura ML, Dao SD, Co EG, Roizen MF, Mazel P, Gilman R, Shokes L, Trevor AJ.

Am J Obstet Gynecol. 1983 Jun 15;146(4):429-34.

PMID:
6859163
24.

Metabolism of phencyclidine. The role of iminium ion formation in covalent binding to rabbit microsomal protein.

Ward DP, Trevor AJ, Kalir A, Adams JD, Baillie TA, Castagnoli N Jr.

Drug Metab Dispos. 1982 Nov-Dec;10(6):690-5.

PMID:
6130925
25.

Derivatization of chiral amines with (S,S)-N-trifluoroacetylproline anhydride for GC estimation of enantiomeric composition.

Adams JD Jr, Woolf TF, Trevor AJ, Williams LR, Castagnoli N Jr.

J Pharm Sci. 1982 Jun;71(6):658-61.

PMID:
7097528
26.

Reductive metabolism of halothane by human and rabbit cytochrome P-450. Binding of 1-chloro-2,2,2-trifluoroethyl radical to phospholipids.

Trudell JR, Bösterling B, Trevor AJ.

Mol Pharmacol. 1982 May;21(3):710-7. No abstract available.

PMID:
7110119
27.
29.

Ketamine--its pharmacology and therapeutic uses.

White PF, Way WL, Trevor AJ.

Anesthesiology. 1982 Feb;56(2):119-36. No abstract available.

PMID:
6892475
30.

Studies on the biotransformation of ketamine. 1-Identification of metabolites produced in vitro from rat liver microsomal preparations.

Adams JD Jr, Baillie TA, Trevor AJ, Castagnoli N Jr.

Biomed Mass Spectrom. 1981 Nov;8(11):527-38.

PMID:
7317567
31.

Chronic phencyclidine induced changes in rat central cholinergic receptor regulation.

Ward DP, Trevor AJ.

Proc West Pharmacol Soc. 1981;24:3-4. No abstract available.

PMID:
7255472
32.

Radioimmunoassay for phencyclidine: application to kinetic analysis in the rat.

Ward DP, Trevor AJ.

Life Sci. 1980 Aug 11;27(6):457-65. No abstract available.

PMID:
7412487
33.

Pharmacology of ketamine isomers in surgical patients.

White PF, Ham J, Way WL, Trevor AJ.

Anesthesiology. 1980 Mar;52(3):231-9. No abstract available.

PMID:
6989292
34.

The effects of ketamine enantiomers on schedule-controlled behavior in the rat.

Meliska CJ, Greenberg AJ, Trevor AJ.

J Pharmacol Exp Ther. 1980 Feb;212(2):198-202.

PMID:
7351632
35.

Spectral studies on the interaction of dichloromethane with hemoglobin.

Harkey MR, Settle WL, James TL, Trevor AJ.

Mol Pharmacol. 1979 Nov;16(3):1065-74. No abstract available.

PMID:
530249
36.

Immunochemical studies of phospholipids: production of antibodies to triphosphoinositide.

Greenberg AJ, Trevor AJ, Johnson DA, Loh HH.

Mol Immunol. 1979 Mar;16(3):193-6. No abstract available.

PMID:
226471
37.

Acetylcholinesterases.

Trevor AJ, Gordon MA, Parker KK, Chan SL.

Life Sci. 1978 Sep 25;23(12):1209-20. Review. No abstract available.

PMID:
362101
38.

Differential effects of ketamine on schedule-controlled responding and motility.

Meliska CJ, Trevor AJ.

Pharmacol Biochem Behav. 1978 Jun;8(6):679-83.

PMID:
693552
39.

Comparative pharmacology of the optical isomers of ketamine in mice.

Ryder S, Way WL, Trevor AJ.

Eur J Pharmacol. 1978 May 1;49(1):15-23.

PMID:
658124
40.

Purification of native forms of eel acetylcholinesterase: active site determination.

Parker KK, Chan SL, Trevor AJ.

Arch Biochem Biophys. 1978 Apr 30;187(2):322-7. No abstract available.

PMID:
666314
41.

Quantitative analysis of ketamine enantiomers.

Adams JD, Castagnoli N, Trevor AJ.

Proc West Pharmacol Soc. 1978;21:471-2. No abstract available.

PMID:
693534
42.

Active site stoichiometry of native forms of eel acetylcholinesterase.

Parker KK, Trevor AJ.

Proc West Pharmacol Soc. 1978;21:221-2. No abstract available.

PMID:
693499
43.

Characterization of ketamine induction of hepatic microsomal drug metabolism.

Marietta MP, Vore ME, Way WL, Trevor AJ.

Biochem Pharmacol. 1977 Dec 15;26(24):2451-3. No abstract available.

PMID:
413552
44.

Divalent cations and the molecular state of brain acetylcholinesterase (E.C. 3.1.1.7.).

Chan SL, Gordon MA, Trevor AJ.

Life Sci. 1977 Dec 1;21(11):1611-6. No abstract available.

PMID:
600014
45.

Kinetic analysis of calcium activation of brain acetylcholinesterase forms.

Gordon MA, Settle WL, Chan SL, Trevor AJ.

Biochim Biophys Acta. 1977 Nov 23;485(1):101-15.

PMID:
20967
46.

Immunochemical studies of mammalian brain acetylcholinesterase.

Greenberg AJ, Parker KK, Trevor AJ.

J Neurochem. 1977 Nov;29(5):911-7. No abstract available.

PMID:
412920
47.

On the pharmacology of the ketamine enantiomorphs in the rat.

Marietta MP, WAY WL, Castagnoli N Jr, Trevor AJ.

J Pharmacol Exp Ther. 1977 Jul;202(1):157-65. No abstract available.

PMID:
874812
48.

Active-site determinations on forms of mammalian brain and eel acetylcholinesterase.

Gordon MA, Chan SL, Trevor AJ.

Biochem J. 1976 Jul 1;157(1):69-76.

49.

Biodisposition of ketamine in the rat: self-induction of metabolism.

Marietta MP, White PF, Pudwill CR, Way WL, Trevor AJ.

J Pharmacol Exp Ther. 1976 Mar;196(3):536-44.

PMID:
1271278
50.

Effects of halothane anesthesia on the biodisposition of ketamine in rats.

White PF, Marietta MP, Pudwill CR, Way WL, Trevor AJ.

J Pharmacol Exp Ther. 1976 Mar;196(3):545-55.

PMID:
1263110

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