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Items: 6

1.

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.

Schalkwijk J, Allman EL, Jansen PAM, de Vries LE, Verhoef JMJ, Jackowski S, Botman PNM, Beuckens-Schortinghuis CA, Koolen KMJ, Bolscher JM, Vos MW, Miller K, Reeves SA, Pett H, Trevitt G, Wittlin S, Scheurer C, Sax S, Fischli C, Angulo-Barturen I, Jiménez-Diaz MB, Josling G, Kooij TWA, Bonnert R, Campo B, Blaauw RH, Rutjes FPJT, Sauerwein RW, Llinás M, Hermkens PHH, Dechering KJ.

Sci Transl Med. 2019 Sep 18;11(510). pii: eaas9917. doi: 10.1126/scitranslmed.aas9917.

PMID:
31534021
2.

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases.

Miglianico M, Eldering M, Slater H, Ferguson N, Ambrose P, Lees RS, Koolen KMJ, Pruzinova K, Jancarova M, Volf P, Koenraadt CJM, Duerr HP, Trevitt G, Yang B, Chatterjee AK, Wisler J, Sturm A, Bousema T, Sauerwein RW, Schultz PG, Tremblay MS, Dechering KJ.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6920-E6926. doi: 10.1073/pnas.1801338115. Epub 2018 Jul 2.

3.

Enantioselective Brønsted acid-catalyzed N-acyliminium cyclization cascades.

Muratore ME, Holloway CA, Pilling AW, Storer RI, Trevitt G, Dixon DJ.

J Am Chem Soc. 2009 Aug 12;131(31):10796-7. doi: 10.1021/ja9024885.

PMID:
19606900
4.

Atropisomeric small molecule Bcl-2 ligands: determination of bioactive conformation.

Porter J, Payne A, Whitcombe I, de Candole B, Ford D, Garlish R, Hold A, Hutchinson B, Trevitt G, Turner J, Edwards C, Watkins C, Davis J, Stubberfield C.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1767-72. doi: 10.1016/j.bmcl.2009.01.071. Epub 2009 Jan 27.

PMID:
19217289
5.

Tetrahydroisoquinoline amide substituted phenyl pyrazoles as selective Bcl-2 inhibitors.

Porter J, Payne A, de Candole B, Ford D, Hutchinson B, Trevitt G, Turner J, Edwards C, Watkins C, Whitcombe I, Davis J, Stubberfield C.

Bioorg Med Chem Lett. 2009 Jan 1;19(1):230-3. doi: 10.1016/j.bmcl.2008.10.113. Epub 2008 Oct 31.

PMID:
19027294
6.

Tandem enantioselective conjugate addition: electrophile trapping reactions. Application in the formation of syn or anti aldols.

Alexakis A, Trevitt GP, Bernardinelli G.

J Am Chem Soc. 2001 May 9;123(18):4358-9. No abstract available.

PMID:
11457212

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