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Items: 1 to 50 of 91

1.

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies.

Gurbatri CR, Lia I, Vincent R, Coker C, Castro S, Treuting PM, Hinchliffe TE, Arpaia N, Danino T.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaax0876. doi: 10.1126/scitranslmed.aax0876.

PMID:
32051224
2.

Effect of Chronic Vitamin D Deficiency on the Development and Severity of DSS-Induced Colon Cancer in Smad3-/- Mice.

Meeker SM, Seamons A, Treuting PM, Paik J, Brabb T, Hsu CC, Grady WM, Maggio-Price L.

Comp Med. 2020 Feb 3. doi: 10.30802/AALAS-CM-19-000021. [Epub ahead of print]

PMID:
32014085
3.

CFTR dysregulation drives active selection of the gut microbiome.

Meeker SM, Mears KS, Sangwan N, Brittnacher MJ, Weiss EJ, Treuting PM, Tolley N, Pope CE, Hager KR, Vo AT, Paik J, Frevert CW, Hayden HS, Hoffman LR, Miller SI, Hajjar AM.

PLoS Pathog. 2020 Jan 21;16(1):e1008251. doi: 10.1371/journal.ppat.1008251. eCollection 2020 Jan.

4.

Lack of Effect of Murine Norovirus Infection on the CD4+ CD45RBhigh T-cell Adoptive Transfer Mouse Model of Inflammatory Bowel Disease.

Hsu CC, Patil K, Seamons A, Brabb TL, Treuting PM, Paik J, Meeker SM, Maggio-Price L.

Comp Med. 2020 Feb 1;70(1):16-24. doi: 10.30802/AALAS-CM-19-000009. Epub 2020 Jan 14.

PMID:
31937392
5.

STING is required for host defense against neuropathological West Nile virus infection.

McGuckin Wuertz K, Treuting PM, Hemann EA, Esser-Nobis K, Snyder AG, Graham JB, Daniels BP, Wilkins C, Snyder JM, Voss KM, Oberst A, Lund J, Gale M Jr.

PLoS Pathog. 2019 Aug 15;15(8):e1007899. doi: 10.1371/journal.ppat.1007899. eCollection 2019 Aug.

6.

Repeated Intraperitoneal Administration of Low-Concentration Methylcellulose Leads to Systemic Histologic Lesions Without Loss of Preclinical Phenotype.

Meeker S, Beckman M, Knox KM, Treuting PM, Barker-Haliski M.

J Pharmacol Exp Ther. 2019 Oct;371(1):25-35. doi: 10.1124/jpet.119.257261. Epub 2019 Aug 2.

PMID:
31375638
7.

An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research.

Brayton CF, Boyd KL, Everitt JL, Meyerholz DK, Treuting PM, Bolon B.

ILAR J. 2018 Dec 1;59(1):1-3. doi: 10.1093/ilar/ilz008.

PMID:
31329902
8.

The devil is in the details-Host disease and co-infections are associated with zoonotic pathogen carriage in Norway rats (Rattus norvegicus).

Rothenburger JL, Himsworth CG, Nemeth NM, Pearl DL, Treuting PM, Jardine CM.

Zoonoses Public Health. 2019 Sep;66(6):622-635. doi: 10.1111/zph.12615. Epub 2019 Jun 20.

PMID:
31222965
9.

The Effect of Mouse Strain, Sex, and Carcinogen Dose on Toxicity and the Development of Lung Dysplasia and Squamous Cell Carcinomas in Mice.

Riolobos L, Gad EA, Treuting PM, Timms AE, Hershberg EA, Corulli LR, Rodmaker E, Disis ML.

Cancer Prev Res (Phila). 2019 Aug;12(8):507-516. doi: 10.1158/1940-6207.CAPR-18-0442. Epub 2019 May 17.

PMID:
31101634
10.

Pathology of wild Norway rats in Vancouver, Canada.

Rothenburger JL, Himsworth CG, La Perle KMD, Leighton FA, Nemeth NM, Treuting PM, Jardine CM.

J Vet Diagn Invest. 2019 Mar;31(2):184-199. doi: 10.1177/1040638719833436.

PMID:
30852980
11.

Histopathological Scoring.

Treuting PM, Boyd KL.

Vet Pathol. 2019 Jan;56(1):17-18. doi: 10.1177/0300985818785699. No abstract available.

PMID:
30791862
12.

Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models.

Everitt JI, Treuting PM, Scudamore C, Sellers R, Turner PV, Ward JM, Zeiss CJ.

ILAR J. 2018 Dec 1;59(1):4-12. doi: 10.1093/ilar/ily020.

PMID:
30624739
13.

Obstructive Lymphangitis Precedes Colitis in Murine Norovirus-Infected Stat1-Deficient Mice.

Seamons A, Treuting PM, Meeker S, Hsu C, Paik J, Brabb T, Escobar SS, Alexander JS, Ericsson AC, Smith JG, Maggio-Price L.

Am J Pathol. 2018 Jul;188(7):1536-1554. doi: 10.1016/j.ajpath.2018.03.019. Epub 2018 May 18.

14.

Can inhibition of retinoic acid biosynthesis function as a non-hormonal female contraceptive?

Paik J, Treuting PM, Haenisch M, Amory JK.

Contraception. 2018 Apr 7. pii: S0010-7824(18)30136-7. doi: 10.1016/j.contraception.2018.03.035. [Epub ahead of print]

15.

Indocyanine green nanoparticles undergo selective lymphatic uptake, distribution and retention and enable detailed mapping of lymph vessels, nodes and abnormalities.

Kraft JC, Treuting PM, Ho RJY.

J Drug Target. 2018 Jun - Jul;26(5-6):494-504. doi: 10.1080/1061186X.2018.1433681. Epub 2018 Feb 12.

16.

Training mouse pathologists: 16th annual workshop on the pathology of mouse models of human disease.

Sundberg JP, Boyd K, Hogenesch H, Nikitin AY, Treuting PM, Ward JM.

Lab Anim (NY). 2018 Jan 31;47(2):38-40. doi: 10.1038/laban.1399. No abstract available.

17.

Proliferative Cartilaginous Lesions in the Calcaneal Tendons of huNOG Mice.

MacLeod AM, Treuting PM, Carlson CS.

Toxicol Pathol. 2017 Oct;45(7):952-956. doi: 10.1177/0192623317734822. Epub 2017 Oct 3.

PMID:
28974149
18.

Corrigendum: Stability and function of regulatory T cells expressing the transcription factor T-bet.

Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY.

Nature. 2017 Sep 20;550(7674):142. doi: 10.1038/nature24013.

PMID:
28953866
19.

Pharmacological inhibition of ALDH1A enzymes suppresses weight gain in a mouse model of diet-induced obesity.

Haenisch M, Treuting PM, Brabb T, Goldstein AS, Berkseth K, Amory JK, Paik J.

Obes Res Clin Pract. 2018 Jan - Feb;12(1):93-101. doi: 10.1016/j.orcp.2017.08.003. Epub 2017 Sep 12.

20.

Stability and function of regulatory T cells expressing the transcription factor T-bet.

Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY.

Nature. 2017 Jun 15;546(7658):421-425. doi: 10.1038/nature22360. Epub 2017 Jun 7. Erratum in: Nature. 2017 Sep 20;:.

21.

Training mouse pathologists: 15 years of workshops on the pathology of mouse models of human disease.

Sundberg JP, Boyd K, Hogenesch H, Nikitin AY, Treuting PM, Ward JM.

Lab Anim (NY). 2017 Apr 19;46(5):204-206. doi: 10.1038/laban.1256. No abstract available.

22.

miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis.

Rosenberger CM, Podyminogin RL, Diercks AH, Treuting PM, Peschon JJ, Rodriguez D, Gundapuneni M, Weiss MJ, Aderem A.

PLoS Pathog. 2017 Apr 5;13(4):e1006305. doi: 10.1371/journal.ppat.1006305. eCollection 2017 Apr.

23.

Authors' Response.

Treuting PM, Hsu C.

Vet Pathol. 2017 Mar;54(2):346-347. doi: 10.1177/0300985816681413. No abstract available.

PMID:
28207375
24.

Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity.

Levine AG, Hemmers S, Baptista AP, Schizas M, Faire MB, Moltedo B, Konopacki C, Schmidt-Supprian M, Germain RN, Treuting PM, Rudensky AY.

J Exp Med. 2017 Mar 6;214(3):609-622. doi: 10.1084/jem.20161318. Epub 2017 Jan 27.

25.

A Mouse Model of Chronic West Nile Virus Disease.

Graham JB, Swarts JL, Wilkins C, Thomas S, Green R, Sekine A, Voss KM, Ireton RC, Mooney M, Choonoo G, Miller DR, Treuting PM, Pardo Manuel de Villena F, Ferris MT, McWeeney S, Gale M Jr, Lund JM.

PLoS Pathog. 2016 Nov 2;12(11):e1005996. doi: 10.1371/journal.ppat.1005996. eCollection 2016 Nov.

26.

Response to "Regarding Mole-rats and Cancer".

Delaney MA, Ward JM, Walsh TF, Chinnadurai SK, Kerns K, Kinsel MJ, Treuting PM.

Vet Pathol. 2016 Nov;53(6):1266-1267. No abstract available.

PMID:
27733704
27.

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice.

Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M.

Elife. 2016 Aug 23;5. pii: e16351. doi: 10.7554/eLife.16351.

28.

Pathology in Practice.

Reyes NL, Treuting PM, Vogel P, Rehg J, Snyder JM.

J Am Vet Med Assoc. 2016 Aug 15;249(4):381-4. doi: 10.2460/javma.249.4.381. No abstract available.

PMID:
27479281
29.

What Is Your Neurologic Diagnosis? Myelopathy in the region of T3 through L2.

Meeker SM, Treuting PM, Maggio-Price L, Snyder JM.

J Am Vet Med Assoc. 2016 Apr 15;248(8):883-5. doi: 10.2460/javma.248.8.883. No abstract available.

PMID:
27031412
30.

Why Animals Die: An Introduction to the Pathology of Aging.

Ward JM, Youssef SA, Treuting PM.

Vet Pathol. 2016 Mar;53(2):229-32. doi: 10.1177/0300985815612151. No abstract available.

PMID:
26936750
31.

Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection.

Gounder AP, Myers ND, Treuting PM, Bromme BA, Wilson SS, Wiens ME, Lu W, Ouellette AJ, Spindler KR, Parks WC, Smith JG.

PLoS Pathog. 2016 Mar 2;12(3):e1005474. doi: 10.1371/journal.ppat.1005474. eCollection 2016 Mar.

32.

Initial Case Reports of Cancer in Naked Mole-rats (Heterocephalus glaber).

Delaney MA, Ward JM, Walsh TF, Chinnadurai SK, Kerns K, Kinsel MJ, Treuting PM.

Vet Pathol. 2016 May;53(3):691-6. doi: 10.1177/0300985816630796. Epub 2016 Feb 4.

PMID:
26846576
33.

Histologic Lesions Induced by Murine Norovirus Infection in Laboratory Mice.

Hsu CC, Piotrowski SL, Meeker SM, Smith KD, Maggio-Price L, Treuting PM.

Vet Pathol. 2016 Jul;53(4):754-63. doi: 10.1177/0300985815618439. Epub 2016 Jan 20. Review.

34.

The Vital Role of Pathology in Improving Reproducibility and Translational Relevance of Aging Studies in Rodents.

Treuting PM, Snyder JM, Ikeno Y, Schofield PN, Ward JM, Sundberg JP.

Vet Pathol. 2016 Mar;53(2):244-9. doi: 10.1177/0300985815620629. Epub 2016 Jan 20.

35.

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.

Pestal K, Funk CC, Snyder JM, Price ND, Treuting PM, Stetson DB.

Immunity. 2015 Nov 17;43(5):933-44. doi: 10.1016/j.immuni.2015.11.001.

36.

Renal Pathology in a Nontraditional Aging Model: The Naked Mole-Rat (Heterocephalus glaber).

Delaney MA, Kinsel MJ, Treuting PM.

Vet Pathol. 2016 Mar;53(2):493-503. doi: 10.1177/0300985815612557. Epub 2015 Nov 16.

PMID:
26574557
37.

Cause-of-Death Analysis in Rodent Aging Studies.

Snyder JM, Ward JM, Treuting PM.

Vet Pathol. 2016 Mar;53(2):233-43. doi: 10.1177/0300985815610391. Epub 2015 Oct 27. Review.

PMID:
26508696
38.

Mouse Necropsy.

Treuting PM, Snyder JM.

Curr Protoc Mouse Biol. 2015 Sep 1;5(3):223-233. doi: 10.1002/9780470942390.mo140296.

PMID:
26331757
39.

A Distinct Function of Regulatory T Cells in Tissue Protection.

Arpaia N, Green JA, Moltedo B, Arvey A, Hemmers S, Yuan S, Treuting PM, Rudensky AY.

Cell. 2015 Aug 27;162(5):1078-89. doi: 10.1016/j.cell.2015.08.021.

40.

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.

Gray EE, Treuting PM, Woodward JJ, Stetson DB.

J Immunol. 2015 Sep 1;195(5):1939-43. doi: 10.4049/jimmunol.1500969. Epub 2015 Jul 29.

41.

CD11b(+) Mononuclear Cells Mitigate Hyperoxia-Induced Lung Injury in Neonatal Mice.

Eldredge LC, Treuting PM, Manicone AM, Ziegler SF, Parks WC, McGuire JK.

Am J Respir Cell Mol Biol. 2016 Feb;54(2):273-83. doi: 10.1165/rcmb.2014-0395OC.

42.

Respiratory Pathology and Pathogens in Wild Urban Rats (Rattus norvegicus and Rattus rattus).

Rothenburger JL, Himsworth CG, Clifford CB, Ellis J, Treuting PM, Leighton FA.

Vet Pathol. 2015 Nov;52(6):1210-9. doi: 10.1177/0300985815593123. Epub 2015 Jul 13.

PMID:
26169386
43.

Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes.

Graham JB, Thomas S, Swarts J, McMillan AA, Ferris MT, Suthar MS, Treuting PM, Ireton R, Gale M Jr, Lund JM.

mBio. 2015 May 5;6(3):e00493-15. doi: 10.1128/mBio.00493-15.

44.

Hepatic Lipidosis in a Research Colony of Big Brown Bats (Eptesicus fuscus).

Snyder JM, Treuting PM, Brabb T, Miller KE, Covey E, Lencioni KL.

Comp Med. 2015 Apr;65(2):133-9.

45.

Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.

Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen RS, Stehling-Sun S, Sabo PJ, Byron R, Humbert R, Thurman RE, Johnson AK, Vong S, Lee K, Bates D, Neri F, Diegel M, Giste E, Haugen E, Dunn D, Wilken MS, Josefowicz S, Samstein R, Chang KH, Eichler EE, De Bruijn M, Reh TA, Skoultchi A, Rudensky A, Orkin SH, Papayannopoulou T, Treuting PM, Selleri L, Kaul R, Groudine M, Bender MA, Stamatoyannopoulos JA.

Science. 2014 Nov 21;346(6212):1007-12. doi: 10.1126/science.1246426.

46.

Conservation of trans-acting circuitry during mammalian regulatory evolution.

Stergachis AB, Neph S, Sandstrom R, Haugen E, Reynolds AP, Zhang M, Byron R, Canfield T, Stelhing-Sun S, Lee K, Thurman RE, Vong S, Bates D, Neri F, Diegel M, Giste E, Dunn D, Vierstra J, Hansen RS, Johnson AK, Sabo PJ, Wilken MS, Reh TA, Treuting PM, Kaul R, Groudine M, Bender MA, Borenstein E, Stamatoyannopoulos JA.

Nature. 2014 Nov 20;515(7527):365-70. doi: 10.1038/nature13972.

47.

Natural history of tumor growth and immune modulation in common spontaneous murine mammary tumor models.

Gad E, Rastetter L, Slota M, Koehnlein M, Treuting PM, Dang Y, Stanton S, Disis ML.

Breast Cancer Res Treat. 2014 Dec;148(3):501-10. doi: 10.1007/s10549-014-3199-9. Epub 2014 Nov 14.

48.

Infection with murine norovirus 4 does not alter Helicobacter-induced inflammatory bowel disease in Il10(-/-) mice.

Hsu CC, Paik J, Treuting PM, Seamons A, Meeker SM, Brabb TL, Maggio-Price L.

Comp Med. 2014 Aug;64(4):256-63.

49.

Humanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.

Snyder JM, Treuting PM, Nagy L, Yam C, Yi J, Brasfield A, Nguyen LP, Hajjar AM.

PLoS One. 2014 Sep 17;9(9):e107257. doi: 10.1371/journal.pone.0107257. eCollection 2014.

50.

Lesions associated with Eucoleus sp. in the non-glandular stomach of wild urban rats (Rattus norvegicus).

Rothenburger JL, Himsworth CG, Lejeune M, Treuting PM, Leighton FA.

Int J Parasitol Parasites Wildl. 2014 May 10;3(2):95-101. doi: 10.1016/j.ijppaw.2014.04.003. eCollection 2014 Aug.

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