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Items: 43


CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma.

Lepore F, D'Alessandro G, Antonangeli F, Santoro A, Esposito V, Limatola C, Trettel F.

Front Immunol. 2018 Nov 27;9:2750. doi: 10.3389/fimmu.2018.02750. eCollection 2018.


The Glycoside Oleandrin Reduces Glioma Growth with Direct and Indirect Effects on Tumor Cells.

Garofalo S, Grimaldi A, Chece G, Porzia A, Morrone S, Mainiero F, D'Alessandro G, Esposito V, Cortese B, Di Angelantonio S, Trettel F, Limatola C.

J Neurosci. 2017 Apr 5;37(14):3926-3939. doi: 10.1523/JNEUROSCI.2296-16.2017. Epub 2017 Mar 14.


The chemokine CXCL16 modulates neurotransmitter release in hippocampal CA1 area.

Di Castro MA, Trettel F, Milior G, Maggi L, Ragozzino D, Limatola C.

Sci Rep. 2016 Oct 10;6:34633. doi: 10.1038/srep34633.


Basal adenosine modulates the functional properties of AMPA receptors in mouse hippocampal neurons through the activation of A1R A2AR and A3R.

Di Angelantonio S, Bertollini C, Piccinin S, Rosito M, Trettel F, Pagani F, Limatola C, Ragozzino D.

Front Cell Neurosci. 2015 Oct 12;9:409. doi: 10.3389/fncel.2015.00409. eCollection 2015.


Fractalkine in the nervous system: neuroprotective or neurotoxic molecule?

Lauro C, Catalano M, Trettel F, Limatola C.

Ann N Y Acad Sci. 2015 Sep;1351:141-8. doi: 10.1111/nyas.12805. Epub 2015 Jun 17. Review.


Editorial Research Topic "Chemokines and chemokine receptors in brain homeostasis".

Ransohoff RM, Trettel F.

Front Cell Neurosci. 2015 Apr 8;9:132. doi: 10.3389/fncel.2015.00132. eCollection 2015. No abstract available.


Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation.

Lauro C, Catalano M, Di Paolo E, Chece G, de Costanzo I, Trettel F, Limatola C.

Front Cell Neurosci. 2015 Jan 21;8:472. doi: 10.3389/fncel.2014.00472. eCollection 2014.


Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death.

Rosito M, Lauro C, Chece G, Porzia A, Monaco L, Mainiero F, Catalano M, Limatola C, Trettel F.

Front Cell Neurosci. 2014 Jul 10;8:193. doi: 10.3389/fncel.2014.00193. eCollection 2014.


CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNS.

Rosito M, Deflorio C, Limatola C, Trettel F.

J Neurosci. 2012 Feb 29;32(9):3154-63. doi: 10.1523/JNEUROSCI.4046-11.2012.


Adenosine A2A receptor induces protein kinase A-dependent functional modulation of human (alpha)3(beta)4 nicotinic receptor.

Di Angelantonio S, Piccioni A, Moriconi C, Trettel F, Cristalli G, Grassi F, Limatola C.

J Physiol. 2011 Jun 1;589(Pt 11):2755-66. doi: 10.1113/jphysiol.2011.207282. Epub 2011 Apr 11.


Mutant human β4 subunit identified in amyotrophic lateral sclerosis patients impairs nicotinic receptor function.

Moriconi C, Di Angelantonio S, Piccioni A, Trettel F, Sabatelli M, Grassi F.

Pflugers Arch. 2011 Feb;461(2):225-33. doi: 10.1007/s00424-010-0905-2. Epub 2010 Nov 25.


Chemokines and chemokine receptors in the nervous system. Rome, 24/25 October, 2009, 2nd workshop.

Trettel F, Di Angelantonio S, Limatola C, Ransohoff RM.

J Neuroimmunol. 2010 Jul 27;224(1-2):1-7. doi: 10.1016/j.jneuroim.2010.05.001. Epub 2010 Jun 11. No abstract available.


Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.

Lauro C, Cipriani R, Catalano M, Trettel F, Chece G, Brusadin V, Antonilli L, van Rooijen N, Eusebi F, Fredholm BB, Limatola C.

Neuropsychopharmacology. 2010 Jun;35(7):1550-9. doi: 10.1038/npp.2010.26. Epub 2010 Mar 3.


LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R).

Maggi L, Trettel F, Scianni M, Bertollini C, Eusebi F, Fredholm BB, Limatola C.

J Neuroimmunol. 2009 Oct 30;215(1-2):36-42. doi: 10.1016/j.jneuroim.2009.07.016. Epub 2009 Aug 26.


Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis.

Sabatelli M, Eusebi F, Al-Chalabi A, Conte A, Madia F, Luigetti M, Mancuso I, Limatola C, Trettel F, Sobrero F, Di Angelantonio S, Grassi F, Di Castro A, Moriconi C, Fucile S, Lattante S, Marangi G, Murdolo M, Orteschi D, Del Grande A, Tonali P, Neri G, Zollino M.

Hum Mol Genet. 2009 Oct 15;18(20):3997-4006. doi: 10.1093/hmg/ddp339. Epub 2009 Jul 23.


Chemokines and chemokine receptors in the nervous system Rome, 27/28 October, 2007.

Trettel F, Di Angelantonio S, Limatola C, Ransohoff RM.

J Neuroimmunol. 2008 Jul 31;198(1-2):1-8. doi: 10.1016/j.jneuroim.2008.04.006. Epub 2008 May 29. Review. No abstract available.


Chemokine CXCL8 modulates GluR1 phosphorylation.

Catalano M, Trettel F, Cipriani R, Lauro C, Sobrero F, Eusebi F, Limatola C.

J Neuroimmunol. 2008 Jul 31;198(1-2):75-81. doi: 10.1016/j.jneuroim.2008.04.017. Epub 2008 May 27.


The chemokine CX3CL1 reduces migration and increases adhesion of neurons with mechanisms dependent on the beta1 integrin subunit.

Lauro C, Catalano M, Trettel F, Mainiero F, Ciotti MT, Eusebi F, Limatola C.

J Immunol. 2006 Dec 1;177(11):7599-606.


Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons.

Ragozzino D, Di Angelantonio S, Trettel F, Bertollini C, Maggi L, Gross C, Charo IF, Limatola C, Eusebi F.

J Neurosci. 2006 Oct 11;26(41):10488-98.


Cysteine residues are critical for chemokine receptor CXCR2 functional properties.

Limatola C, Di Bartolomeo S, Catalano M, Trettel F, Fucile S, Castellani L, Eusebi F.

Exp Cell Res. 2005 Jul 1;307(1):65-75. Epub 2005 Mar 24.


BDNF modulates GABAA receptors microtransplanted from the human epileptic brain to Xenopus oocytes.

Palma E, Torchia G, Limatola C, Trettel F, Arcella A, Cantore G, Di Gennaro G, Manfredi M, Esposito V, Quarato PP, Miledi R, Eusebi F.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1667-72. Epub 2005 Jan 21.


Phosphatase inhibitors remove the run-down of gamma-aminobutyric acid type A receptors in the human epileptic brain.

Palma E, Ragozzino DA, Di Angelantonio S, Spinelli G, Trettel F, Martinez-Torres A, Torchia G, Arcella A, Di Gennaro G, Quarato PP, Esposito V, Cantore G, Miledi R, Eusebi F.

Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10183-8. Epub 2004 Jun 24.


Ligand-independent CXCR2 dimerization.

Trettel F, Di Bartolomeo S, Lauro C, Catalano M, Ciotti MT, Limatola C.

J Biol Chem. 2003 Oct 17;278(42):40980-8. Epub 2003 Jul 28.


Microtransplantation of membranes from cultured cells to Xenopus oocytes: a method to study neurotransmitter receptors embedded in native lipids.

Palma E, Trettel F, Fucile S, Renzi M, Miledi R, Eusebi F.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2896-900. Epub 2003 Feb 20.


Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice.

Gines S, Seong IS, Fossale E, Ivanova E, Trettel F, Gusella JF, Wheeler VC, Persichetti F, MacDonald ME.

Hum Mol Genet. 2003 Mar 1;12(5):497-508.


Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells.

Floridi F, Trettel F, Di Bartolomeo S, Ciotti MT, Limatola C.

J Neuroimmunol. 2003 Feb;135(1-2):38-46.


Expression of AMPA-type glutamate receptors in HEK cells and cerebellar granule neurons impairs CXCL2-mediated chemotaxis.

Limatola C, Di Bartolomeo S, Trettel F, Lauro C, Ciotti MT, Mercanti D, Castellani L, Eusebi F.

J Neuroimmunol. 2003 Jan;134(1-2):61-71.


Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy.

Palma E, Esposito V, Mileo AM, Di Gennaro G, Quarato P, Giangaspero F, Scoppetta C, Onorati P, Trettel F, Miledi R, Eusebi F.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15078-83. Epub 2002 Oct 30.


Expression of functional neurotransmitter receptors in Xenopus oocytes after injection of human brain membranes.

Miledi R, Eusebi F, Martínez-Torres A, Palma E, Trettel F.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13238-42. Epub 2002 Sep 17.


Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells.

Lax P, Limatola C, Fucile S, Trettel F, Di Bartolomeo S, Renzi M, Ragozzino D, Eusebi F.

J Neuroimmunol. 2002 Aug;129(1-2):66-73.


TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.

Brummelkamp TR, Kortlever RM, Lingbeek M, Trettel F, MacDonald ME, van Lohuizen M, Bernards R.

J Biol Chem. 2002 Feb 22;277(8):6567-72. Epub 2001 Dec 17.


Complete loss of P/Q calcium channel activity caused by a CACNA1A missense mutation carried by patients with episodic ataxia type 2.

Guida S, Trettel F, Pagnutti S, Mantuano E, Tottene A, Veneziano L, Fellin T, Spadaro M, Stauderman K, Williams M, Volsen S, Ophoff R, Frants R, Jodice C, Frontali M, Pietrobon D.

Am J Hum Genet. 2001 Mar;68(3):759-64. Epub 2001 Feb 1.


Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells.

Trettel F, Rigamonti D, Hilditch-Maguire P, Wheeler VC, Sharp AH, Persichetti F, Cattaneo E, MacDonald ME.

Hum Mol Genet. 2000 Nov 22;9(19):2799-809.


Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.

Hilditch-Maguire P, Trettel F, Passani LA, Auerbach A, Persichetti F, MacDonald ME.

Hum Mol Genet. 2000 Nov 22;9(19):2789-97.


A fine physical map of the CACNA1A gene region on 19p13.1-p13.2 chromosome.

Trettel F, Mantuano E, Calabresi V, Veneziano L, Olsen AS, Georgescu A, Gordon L, Sabbadini G, Frontali M, Jodice C.

Gene. 2000 Jan 4;241(1):45-50.


Mutant huntingtin forms in vivo complexes with distinct context-dependent conformations of the polyglutamine segment.

Persichetti F, Trettel F, Huang CC, Fraefel C, Timmers HT, Gusella JF, MacDonald ME.

Neurobiol Dis. 1999 Oct;6(5):364-75.


Two exon-skipping mutations as the molecular basis of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria).

Chambliss KL, Hinson DD, Trettel F, Malaspina P, Novelletto A, Jakobs C, Gibson KM.

Am J Hum Genet. 1998 Aug;63(2):399-408.


Localization and genomic structure of human deoxyhypusine synthase gene on chromosome 19p13.2-distal 19p13.1.

Mantuano E, Trettel F, Olsen AS, Lennon G, Frontali M, Jodice C.

Gene. 1998 Jul 17;215(1):153-7.


Episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6) due to CAG repeat expansion in the CACNA1A gene on chromosome 19p.

Jodice C, Mantuano E, Veneziano L, Trettel F, Sabbadini G, Calandriello L, Francia A, Spadaro M, Pierelli F, Salvi F, Ophoff RA, Frants RR, Frontali M.

Hum Mol Genet. 1997 Oct;6(11):1973-8.


Acetazolamide-responsive episodic ataxia in an Italian family refines gene mapping on chromosome 19p13.

Calandriello L, Veneziano L, Francia A, Sabbadini G, Colonnese C, Mantuano E, Jodice C, Trettel F, Viviani P, Manfredi M, Frontali M.

Brain. 1997 May;120 ( Pt 5):805-12.


Human succinic semialdehyde dehydrogenase. Molecular cloning and chromosomal localization.

Trettel F, Malaspina P, Jodice C, Novelletto A, Slaughter CA, Caudle DL, Hinson DD, Chambliss KL, Gibson KM.

Adv Exp Med Biol. 1997;414:253-60. No abstract available.


Construction of a YAC contig covering human chromosome 6p22.

Malaspina P, Roetto A, Trettel F, Jodice C, Blasi P, Frontali M, Carella M, Franco B, Camaschella C, Novelletto A.

Genomics. 1996 Sep 15;36(3):399-407.


Ordering of 44 genetic markers in the 6p22 cytogenetic band.

Trettel F, Malaspina P, Blasi P, Jodice C, Novelletto A, Sabbadini G, Veneziano L, Frontali M, Terrenato L.

DNA Seq. 1996;7(1):51-2. No abstract available.


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