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Items: 1 to 50 of 833

1.

Correction to: Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution.

Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, Castle JC, Buell JS, Trent JC, Wilky BA.

J Immunother Cancer. 2019 Nov 6;7(1):285. doi: 10.1186/s40425-019-0792-9.

2.

A Case of Possible Monosodium Glutamate-Dependent, Exercise-Induced Anaphylaxis.

Trent JS, Tassin S.

Cureus. 2019 Aug 8;11(8):e5345. doi: 10.7759/cureus.5345.

3.

Risk estimation, anxiety, and breast cancer worry in women at risk for breast cancer: A single-arm trial of personalized risk communication.

Xie Z, Wenger N, Stanton AL, Sepucha K, Kaplan C, Madlensky L, Elashoff D, Trent J, Petruse A, Johansen L, Layton T, Naeim A.

Psychooncology. 2019 Nov;28(11):2226-2232. doi: 10.1002/pon.5211. Epub 2019 Sep 2.

PMID:
31461546
4.

Identification of Recurrent Activating HER2 Mutations in Primary Canine Pulmonary Adenocarcinoma.

Lorch G, Sivaprakasam K, Zismann V, Perdigones N, Contente-Cuomo T, Nazareno A, Facista S, Wong S, Drenner K, Liang WS, Amann JM, Sinicropi-Yao SL, Koenig MJ, La Perle K, Whitsett TG, Murtaza M, Trent JM, Carbone DP, Hendricks WPD.

Clin Cancer Res. 2019 Oct 1;25(19):5866-5877. doi: 10.1158/1078-0432.CCR-19-1145. Epub 2019 Aug 20.

PMID:
31431454
5.

Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution.

Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, Castle JC, Buell JS, Trent JC, Wilky BA.

J Immunother Cancer. 2019 Aug 8;7(1):213. doi: 10.1186/s40425-019-0689-7. Erratum in: J Immunother Cancer. 2019 Nov 6;7(1):285.

6.

Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2.

Gardner HL, Sivaprakasam K, Briones N, Zismann V, Perdigones N, Drenner K, Facista S, Richholt R, Liang W, Aldrich J, Trent JM, Shields PG, Robinson N, Johnson J, Lana S, Houghton P, Fenger J, Lorch G, Janeway KA, London CA, Hendricks WPD.

Commun Biol. 2019 Jul 19;2:266. doi: 10.1038/s42003-019-0487-2. eCollection 2019.

7.

Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study.

Lowery MA, Burris HA 3rd, Janku F, Shroff RT, Cleary JM, Azad NS, Goyal L, Maher EA, Gore L, Hollebecque A, Beeram M, Trent JC, Jiang L, Fan B, Aguado-Fraile E, Choe S, Wu B, Gliser C, Agresta SV, Pandya SS, Zhu AX, Abou-Alfa GK.

Lancet Gastroenterol Hepatol. 2019 Sep;4(9):711-720. doi: 10.1016/S2468-1253(19)30189-X. Epub 2019 Jul 9.

PMID:
31300360
8.

Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.

Khan N, Shah PP, Ban D, Trigo-Mouriño P, Carneiro MG, DeLeeuw L, Dean WL, Trent JO, Beverly LJ, Konrad M, Lee D, Sabo TM.

J Biol Chem. 2019 Aug 2;294(31):11920-11933. doi: 10.1074/jbc.RA119.009251. Epub 2019 Jun 14.

PMID:
31201273
9.

Wanna Get Away? Maintenance Treatments and Chemotherapy Holidays in Gynecologic Cancers.

Madariaga A, Rustin GJS, Buckanovich RJ, Trent JC, Oza AM.

Am Soc Clin Oncol Educ Book. 2019 Jan;39:e152-e166. doi: 10.1200/EDBK_238755. Epub 2019 May 17. Review.

10.

Editor's Note: Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment.

Yang J, Ylipää A, Sun Y, Zheng H, Chen K, Nykter M, Trent J, Ratner N, Lev DC, Zhang W.

Clin Cancer Res. 2019 May 15;25(10):3195. doi: 10.1158/1078-0432.CCR-19-1144. No abstract available.

PMID:
31092619
11.

Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial.

Wilky BA, Trucco MM, Subhawong TK, Florou V, Park W, Kwon D, Wieder ED, Kolonias D, Rosenberg AE, Kerr DA, Sfakianaki E, Foley M, Merchan JR, Komanduri KV, Trent JC.

Lancet Oncol. 2019 Jun;20(6):837-848. doi: 10.1016/S1470-2045(19)30153-6. Epub 2019 May 8.

PMID:
31078463
12.

Implementing a Population-Based Breast Cancer Risk Assessment Program.

Silver E, Wenger N, Xie Z, Elashoff D, Lee K, Madlensky L, Trent J, Petruse A, Johansen L, Naeim A.

Clin Breast Cancer. 2019 Aug;19(4):246-253.e2. doi: 10.1016/j.clbc.2019.02.009. Epub 2019 Mar 11.

13.

A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas.

Jones RL, Chawla SP, Attia S, Schöffski P, Gelderblom H, Chmielowski B, Le Cesne A, Van Tine BA, Trent JC, Patel S, Wagner AJ, Chugh R, Heyburn JW, Weil SC, Wang W, Viele K, Maki RG.

Cancer. 2019 Jul 15;125(14):2445-2454. doi: 10.1002/cncr.32084. Epub 2019 Apr 29.

14.

Folding Landscape of a Parallel G-Quadruplex.

Gray RD, Trent JO, Arumugam S, Chaires JB.

J Phys Chem Lett. 2019 Mar 7;10(5):1146-1151. doi: 10.1021/acs.jpclett.9b00227. Epub 2019 Feb 27.

PMID:
30802054
15.

Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility.

Chen H, Chen G, Li G, Zhang S, Chen H, Chen Y, Duggan D, Hu Z, Chen J, Zhao Y, Zhao Y, Huang H, Zheng SL, Trent JM, Yu L, Jiang D, Mo Z, Wang H, Mou Y, Jiang T, Mao Y, Xu J, Lu D.

Int J Cancer. 2019 Nov 1;145(9):2372-2382. doi: 10.1002/ijc.32179. Epub 2019 Mar 18.

PMID:
30714141
16.

How we use pazopanib in treating soft-tissue sarcoma: experience at our multidisciplinary sarcoma centers.

Van Tine BA, Trent JC.

Curr Med Res Opin. 2019 Apr;35(4):623-629. doi: 10.1080/03007995.2019.1570768. Epub 2019 Feb 4.

PMID:
30652922
17.

Efficacy and Tolerability of 5-Year Adjuvant Imatinib Treatment for Patients With Resected Intermediate- or High-Risk Primary Gastrointestinal Stromal Tumor: The PERSIST-5 Clinical Trial.

Raut CP, Espat NJ, Maki RG, Araujo DM, Trent J, Williams TF, Purkayastha DD, DeMatteo RP.

JAMA Oncol. 2018 Dec 1;4(12):e184060. doi: 10.1001/jamaoncol.2018.4060. Epub 2018 Dec 13.

18.

E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases.

Babiker HM, Byron SA, Hendricks WPD, Elmquist WF, Gampa G, Vondrak J, Aldrich J, Cuyugan L, Adkins J, De Luca V, Tibes R, Borad MJ, Marceau K, Myers TJ, Paradiso LJ, Liang WS, Korn RL, Cridebring D, Von Hoff DD, Carpten JD, Craig DW, Trent JM, Gordon MS.

Invest New Drugs. 2019 Aug;37(4):636-645. doi: 10.1007/s10637-018-0668-8. Epub 2018 Sep 28.

PMID:
30264293
19.

Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.

Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Santos ND, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, Weissman BE, Huntsman DG.

Mol Cancer Ther. 2018 Dec;17(12):2767-2779. doi: 10.1158/1535-7163.MCT-18-0348. Epub 2018 Sep 19.

20.

Neoadjuvant Chemotherapy, Concurrent Chemoradiation, and Adjuvant Chemotherapy for High-Risk Extremity Soft Tissue Sarcoma.

Baldini EH, Le Cesne A, Trent JC.

Am Soc Clin Oncol Educ Book. 2018 May 23;38:910-915. doi: 10.1200/EDBK_201421. Review.

21.

Notch pathway inhibition with LY3039478 in soft tissue sarcoma and gastrointestinal stromal tumours.

Mir O, Azaro A, Merchan J, Chugh R, Trent J, Rodon J, Ohnmacht U, Diener JT, Smith C, Yuen E, Oakley GJ 3rd, Le Cesne A, Soria JC, Benhadji KA, Massard C.

Eur J Cancer. 2018 Nov;103:88-97. doi: 10.1016/j.ejca.2018.08.012. Epub 2018 Sep 12.

PMID:
30218977
22.

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis.

Hendricks WPD, Zismann V, Sivaprakasam K, Legendre C, Poorman K, Tembe W, Perdigones N, Kiefer J, Liang W, DeLuca V, Stark M, Ruhe A, Froman R, Duesbery NS, Washington M, Aldrich J, Neff MW, Huentelman MJ, Hayward N, Brown K, Thamm D, Post G, Khanna C, Davis B, Breen M, Sekulic A, Trent JM.

PLoS Genet. 2018 Sep 6;14(9):e1007589. doi: 10.1371/journal.pgen.1007589. eCollection 2018 Sep.

23.

Network Rewiring in Cancer: Applications to Melanoma Cell Lines and the Cancer Genome Atlas Patients.

Ding KF, Finlay D, Yin H, Hendricks WPD, Sereduk C, Kiefer J, Sekulic A, LoRusso PM, Vuori K, Trent JM, Schork NJ.

Front Genet. 2018 Jul 10;9:228. doi: 10.3389/fgene.2018.00228. eCollection 2018.

24.

A nonrandom association of sarcoidosis in patients with gastrointestinal stromal tumor and other sarcomas.

Espejo AP, Ramdial JL, Wilky BA, Kerr DA, Trent JC.

Rare Tumors. 2018 Jul 18;10:2036361318787626. doi: 10.1177/2036361318787626. eCollection 2018.

25.

Limb-sparing surgery plus radiotherapy results in superior survival: an analysis of patients with high-grade, extremity soft-tissue sarcoma from the NCDB and SEER.

Ramey SJ, Yechieli R, Zhao W, Kodiyan J, Asher D, Chinea FM, Patel V, Reis IM, Wang L, Wilky BA, Subhawong T, Trent JC 2nd.

Cancer Med. 2018 Sep;7(9):4228-4239. doi: 10.1002/cam4.1625. Epub 2018 Jul 20.

26.

G-quadruplex virtual drug screening: A review.

Monsen RC, Trent JO.

Biochimie. 2018 Sep;152:134-148. doi: 10.1016/j.biochi.2018.06.024. Epub 2018 Jun 30. Review.

27.

Use of Tyrosine Kinase Inhibitors in Patients With GI Stromal Tumor Who Are Pregnant or Considering Pregnancy: Driver Mutations and Circulating Tumor DNA.

Florou V, Ramdial JL, Trent JC.

J Clin Oncol. 2018 Sep 1;36(25):2659-2660. doi: 10.1200/JCO.2018.79.0501. Epub 2018 May 31. No abstract available.

PMID:
29851548
28.

System Redesign of a Radiology Research Clinic for Oncology Clinical Trial Patients.

Gjolaj L, Dang A, Peck H, Trent J, Castillo RP.

J Am Coll Radiol. 2018 Sep;15(9):1304-1308. doi: 10.1016/j.jacr.2018.04.019. Epub 2018 May 24. No abstract available.

PMID:
29804825
29.

Evaluation of pre-analytical factors affecting plasma DNA analysis.

Markus H, Contente-Cuomo T, Farooq M, Liang WS, Borad MJ, Sivakumar S, Gollins S, Tran NL, Dhruv HD, Berens ME, Bryce A, Sekulic A, Ribas A, Trent JM, LoRusso PM, Murtaza M.

Sci Rep. 2018 May 9;8(1):7375. doi: 10.1038/s41598-018-25810-0.

30.

A precision medicine approach in sarcoma: identification of patients who may benefit from early use of pazopanib.

Alavi SN, Florou V, Tinoco G, Trent JC, Wilky BA.

Discov Med. 2018 Mar;25(137):131-144. Review.

31.

Identification of G-quadruplex forming sequences in three manatee papillomaviruses.

Zahin M, Dean WL, Ghim SJ, Joh J, Gray RD, Khanal S, Bossart GD, Mignucci-Giannoni AA, Rouchka EC, Jenson AB, Trent JO, Chaires JB, Chariker JH.

PLoS One. 2018 Apr 9;13(4):e0195625. doi: 10.1371/journal.pone.0195625. eCollection 2018.

32.

Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition.

Lang JD, Hendricks WPD, Orlando KA, Yin H, Kiefer J, Ramos P, Sharma R, Pirrotte P, Raupach EA, Sereduk C, Tang N, Liang WS, Washington M, Facista SJ, Zismann VL, Cousins EM, Major MB, Wang Y, Karnezis AN, Sekulic A, Hass R, Vanderhyden BC, Nair P, Weissman BE, Huntsman DG, Trent JM.

Clin Cancer Res. 2018 Apr 15;24(8):1932-1943. doi: 10.1158/1078-0432.CCR-17-1928. Epub 2018 Feb 9.

33.

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis.

Ding KF, Petricoin EF, Finlay D, Yin H, Hendricks WPD, Sereduk C, Kiefer J, Sekulic A, LoRusso PM, Vuori K, Trent JM, Schork NJ.

Oncotarget. 2017 Dec 15;9(4):5044-5057. doi: 10.18632/oncotarget.23495. eCollection 2018 Jan 12.

34.

Gastrointestinal Stromal Tumors: The GIST of Precision Medicine.

Mei L, Smith SC, Faber AC, Trent J, Grossman SR, Stratakis CA, Boikos SA.

Trends Cancer. 2018 Jan;4(1):74-91. doi: 10.1016/j.trecan.2017.11.006. Epub 2017 Dec 23. Review.

PMID:
29413424
35.

A rapid fluorescent indicator displacement assay and principal component/cluster data analysis for determination of ligand-nucleic acid structural selectivity.

Del Villar-Guerra R, Gray RD, Trent JO, Chaires JB.

Nucleic Acids Res. 2018 Apr 20;46(7):e41. doi: 10.1093/nar/gky019.

36.

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.

Swords RT, Azzam D, Al-Ali H, Lohse I, Volmar CH, Watts JM, Perez A, Rodriguez A, Vargas F, Elias R, Vega F, Zelent A, Brothers SP, Abbasi T, Trent J, Rangwala S, Deutsch Y, Conneally E, Drusbosky L, Cogle CR, Wahlestedt C.

Leuk Res. 2018 Jan;64:34-41. doi: 10.1016/j.leukres.2017.11.008. Epub 2017 Nov 11.

37.

G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy.

Del Villar-Guerra R, Trent JO, Chaires JB.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7171-7175. doi: 10.1002/anie.201709184. Epub 2018 Apr 25.

38.

Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma.

Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, Maggiora GM, Peng S, Nasser S, Liang WS, Trent JM, Berens ME, Carpten JD, Craig DW, Prados MD.

Clin Cancer Res. 2018 Jan 15;24(2):295-305. doi: 10.1158/1078-0432.CCR-17-0963. Epub 2017 Oct 26.

39.

Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus Carcinoma.

Cornelius A, Foley J, Bond J, Nagulapally AB, Steinbrecher J, Hendricks WPD, Rich M, Yendrembam S, Bergendahl G, Trent JM, Sholler GS.

Front Pharmacol. 2017 Sep 25;8:652. doi: 10.3389/fphar.2017.00652. eCollection 2017.

40.

Latest advances in adult gastrointestinal stromal tumors.

Florou V, Wilky BA, Trent JC.

Future Oncol. 2017 Oct;13(24):2183-2193. doi: 10.2217/fon-2017-0245. Epub 2017 Oct 6. Review.

PMID:
28984483
41.

Metabolic Enzymes in Sarcomagenesis: Progress Toward Biology and Therapy.

Li L, Eid JE, Paz AC, Trent JC.

BioDrugs. 2017 Oct;31(5):379-392. doi: 10.1007/s40259-017-0237-2. Review.

PMID:
28840584
42.

A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.

Choi J, Xu M, Makowski MM, Zhang T, Law MH, Kovacs MA, Granzhan A, Kim WJ, Parikh H, Gartside M, Trent JM, Teulade-Fichou MP, Iles MM, Newton-Bishop JA, Bishop DT, MacGregor S, Hayward NK, Vermeulen M, Brown KM.

Nat Genet. 2017 Sep;49(9):1326-1335. doi: 10.1038/ng.3927. Epub 2017 Jul 31.

43.

Impact of Chromosomal Rearrangement upon DNA Methylation Patterns in Leukemia.

Byun HM, Eshaghian S, Douer D, Trent J, Garcia-Manero G, Bhatia R, Siegmund K, Yang AS.

Open Med (Wars). 2017 May 4;12:76-85. doi: 10.1515/med-2017-0014. eCollection 2017.

44.

Estimating Inorganic Arsenic Exposure from U.S. Rice and Total Water Intakes.

Mantha M, Yeary E, Trent J, Creed PA, Kubachka K, Hanley T, Shockey N, Heitkemper D, Caruso J, Xue J, Rice G, Wymer L, Creed JT.

Environ Health Perspect. 2017 May 30;125(5):057005. doi: 10.1289/EHP418.

45.

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

Wang Y, Chen SY, Karnezis AN, Colborne S, Santos ND, Lang JD, Hendricks WP, Orlando KA, Yap D, Kommoss F, Bally MB, Morin GB, Trent JM, Weissman BE, Huntsman DG.

J Pathol. 2017 Jul;242(3):371-383. doi: 10.1002/path.4912. Epub 2017 Jun 2.

46.

Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma.

Liang WS, Hendricks W, Kiefer J, Schmidt J, Sekar S, Carpten J, Craig DW, Adkins J, Cuyugan L, Manojlovic Z, Halperin RF, Helland A, Nasser S, Legendre C, Hurley LH, Sivaprakasam K, Johnson DB, Crandall H, Busam KJ, Zismann V, Deluca V, Lee J, Sekulic A, Ariyan CE, Sosman J, Trent J.

Genome Res. 2017 Apr;27(4):524-532. doi: 10.1101/gr.213348.116.

47.

Analysis of variability in high throughput screening data: applications to melanoma cell lines and drug responses.

Ding KF, Finlay D, Yin H, Hendricks WPD, Sereduk C, Kiefer J, Sekulic A, LoRusso PM, Vuori K, Trent JM, Schork NJ.

Oncotarget. 2017 Apr 25;8(17):27786-27799. doi: 10.18632/oncotarget.15347.

48.

Current status of immunotherapy for gastrointestinal stromal tumor.

Tan Y, Trent JC, Wilky BA, Kerr DA, Rosenberg AE.

Cancer Gene Ther. 2017 Mar;24(3):130-133. doi: 10.1038/cgt.2016.58. Epub 2017 Feb 10. Review.

PMID:
28186088
49.

SDHD Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma.

Zhang T, Xu M, Makowski MM, Lee C, Kovacs M, Fang J, Willems E, Trent JM, Hayward NK, Vermeulen M, Brown KM.

Cancer Res. 2017 Apr 1;77(7):1649-1661. doi: 10.1158/0008-5472.CAN-16-0919. Epub 2017 Jan 20.

50.

Surgical Management of Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Pediatric and Wildtype GIST Clinic.

Weldon CB, Madenci AL, Boikos SA, Janeway KA, George S, von Mehren M, Pappo AS, Schiffman JD, Wright J, Trent JC, Pacak K, Stratakis CA, Helman LJ, La Quaglia MP.

J Clin Oncol. 2017 Feb 10;35(5):523-528. doi: 10.1200/JCO.2016.68.6733. Epub 2016 Dec 28.

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