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Items: 1 to 50 of 54

1.

Gene editing of the multi-copy H2A.B gene and its importance for fertility.

Anuar ND, Kurscheid S, Field M, Zhang L, Rebar E, Gregory P, Buchou T, Bowles J, Koopman P, Tremethick DJ, Soboleva TA.

Genome Biol. 2019 Jan 31;20(1):23. doi: 10.1186/s13059-019-1633-3.

2.

RChIP-Seq: Chromatin-Associated RNA Sequencing in Developmentally Staged Mouse Testes.

Soboleva TA, Tremethick DJ.

Methods Mol Biol. 2018;1832:169-184. doi: 10.1007/978-1-4939-8663-7_9.

PMID:
30073527
3.

The interplay between H2A.Z and H3K9 methylation in regulating HP1α binding to linker histone-containing chromatin.

Ryan DP, Tremethick DJ.

Nucleic Acids Res. 2018 Oct 12;46(18):9353-9366. doi: 10.1093/nar/gky632.

4.

The Histone Variant H2A.Z Is a Master Regulator of the Epithelial-Mesenchymal Transition.

Domaschenz R, Kurscheid S, Nekrasov M, Han S, Tremethick DJ.

Cell Rep. 2017 Oct 24;21(4):943-952. doi: 10.1016/j.celrep.2017.09.086.

5.

SLY regulates genes involved in chromatin remodeling and interacts with TBL1XR1 during sperm differentiation.

Moretti C, Serrentino ME, Ialy-Radio C, Delessard M, Soboleva TA, Tores F, Leduc M, Nitschké P, Drevet JR, Tremethick DJ, Vaiman D, Kocer A, Cocquet J.

Cell Death Differ. 2017 Jun;24(6):1029-1044. doi: 10.1038/cdd.2017.32. Epub 2017 May 5.

6.

A new link between transcriptional initiation and pre-mRNA splicing: The RNA binding histone variant H2A.B.

Soboleva TA, Parker BJ, Nekrasov M, Hart-Smith G, Tay YJ, Tng WQ, Wilkins M, Ryan D, Tremethick DJ.

PLoS Genet. 2017 Feb 24;13(2):e1006633. doi: 10.1371/journal.pgen.1006633. eCollection 2017 Feb.

7.

A dual affinity-tag strategy for the expression and purification of human linker histone H1.4 in Escherichia coli.

Ryan DP, Tremethick DJ.

Protein Expr Purif. 2016 Apr;120:160-8. doi: 10.1016/j.pep.2015.12.017. Epub 2015 Dec 29.

PMID:
26739785
8.

Histone variants at the transcription start-site.

Soboleva TA, Nekrasov M, Ryan DP, Tremethick DJ.

Trends Genet. 2014 May;30(5):199-209. doi: 10.1016/j.tig.2014.03.002. Epub 2014 Apr 23. Review.

PMID:
24768041
9.

Histone variant selectivity at the transcription start site: H2A.Z or H2A.Lap1.

Nekrasov M, Soboleva TA, Jack C, Tremethick DJ.

Nucleus. 2013 Nov-Dec;4(6):431-8. doi: 10.4161/nucl.26862. Epub 2013 Nov 8.

10.

Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics.

Nekrasov M, Amrichova J, Parker BJ, Soboleva TA, Jack C, Williams R, Huttley GA, Tremethick DJ.

Nat Struct Mol Biol. 2012 Nov;19(11):1076-83. doi: 10.1038/nsmb.2424. Epub 2012 Oct 21.

PMID:
23085713
11.

New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

Luger K, Dechassa ML, Tremethick DJ.

Nat Rev Mol Cell Biol. 2012 Jun 22;13(7):436-47. doi: 10.1038/nrm3382. Review.

12.

A unified phylogeny-based nomenclature for histone variants.

Talbert PB, Ahmad K, Almouzni G, Ausió J, Berger F, Bhalla PL, Bonner WM, Cande WZ, Chadwick BP, Chan SW, Cross GA, Cui L, Dimitrov SI, Doenecke D, Eirin-López JM, Gorovsky MA, Hake SB, Hamkalo BA, Holec S, Jacobsen SE, Kamieniarz K, Khochbin S, Ladurner AG, Landsman D, Latham JA, Loppin B, Malik HS, Marzluff WF, Pehrson JR, Postberg J, Schneider R, Singh MB, Smith MM, Thompson E, Torres-Padilla ME, Tremethick DJ, Turner BM, Waterborg JH, Wollmann H, Yelagandula R, Zhu B, Henikoff S.

Epigenetics Chromatin. 2012 Jun 21;5:7. doi: 10.1186/1756-8935-5-7.

13.

A unique H2A histone variant occupies the transcriptional start site of active genes.

Soboleva TA, Nekrasov M, Pahwa A, Williams R, Huttley GA, Tremethick DJ.

Nat Struct Mol Biol. 2011 Dec 4;19(1):25-30. doi: 10.1038/nsmb.2161.

PMID:
22139013
14.

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer.

Valdés-Mora F, Song JZ, Statham AL, Strbenac D, Robinson MD, Nair SS, Patterson KI, Tremethick DJ, Stirzaker C, Clark SJ.

Genome Res. 2012 Feb;22(2):307-21. doi: 10.1101/gr.118919.110. Epub 2011 Jul 25.

15.

Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression.

Juelich T, Sutcliffe EL, Denton A, He Y, Doherty PC, Parish CR, Turner SJ, Tremethick DJ, Rao S.

J Immunol. 2009 Dec 1;183(11):7063-72. doi: 10.4049/jimmunol.0901522. Epub 2009 Nov 13. Erratum in: J Immunol. 2010 Feb 1;184(3):1653. Sutcliffe, Elissa [corrected to Sutcliffe, Elissa L]; Parish, Christopher [corrected to Parish, Christopher R]; Turner, Steven J [corrected to Turner, Stephen J]; Tremethick, David [corrected to Tremethick, David J].

16.

Specific patterns of histone marks accompany X chromosome inactivation in a marsupial.

Koina E, Chaumeil J, Greaves IK, Tremethick DJ, Graves JA.

Chromosome Res. 2009;17(1):115-26. doi: 10.1007/s10577-009-9020-7. Epub 2009 Feb 13.

PMID:
19214764
17.

Dynamic histone variant exchange accompanies gene induction in T cells.

Sutcliffe EL, Parish IA, He YQ, Juelich T, Tierney ML, Rangasamy D, Milburn PJ, Parish CR, Tremethick DJ, Rao S.

Mol Cell Biol. 2009 Apr;29(7):1972-86. doi: 10.1128/MCB.01590-08. Epub 2009 Jan 21.

18.

Efficient gene delivery using reconstituted chromatin enhanced for nuclear targeting.

Wagstaff KM, Fan JY, De Jesus MA, Tremethick DJ, Jans DA.

FASEB J. 2008 Jul;22(7):2232-42. doi: 10.1096/fj.07-099911. Epub 2008 Mar 20.

PMID:
18356302
19.

Gene knockdown by ecdysone-based inducible RNAi in stable mammalian cell lines.

Rangasamy D, Tremethick DJ, Greaves IK.

Nat Protoc. 2008;3(1):79-88. doi: 10.1038/nprot.2007.456.

PMID:
18193024
20.

The nucleosome surface regulates chromatin compaction and couples it with transcriptional repression.

Zhou J, Fan JY, Rangasamy D, Tremethick DJ.

Nat Struct Mol Biol. 2007 Nov;14(11):1070-6. Epub 2007 Oct 28.

PMID:
17965724
21.

Histone-mediated transduction as an efficient means for gene delivery.

Wagstaff KM, Glover DJ, Tremethick DJ, Jans DA.

Mol Ther. 2007 Apr;15(4):721-31. Epub 2007 Feb 27.

22.

Higher-order structures of chromatin: the elusive 30 nm fiber.

Tremethick DJ.

Cell. 2007 Feb 23;128(4):651-4. Review.

23.

Quantitative analysis of HP1alpha binding to nucleosomal arrays.

Fan JY, Zhou J, Tremethick DJ.

Methods. 2007 Mar;41(3):286-90.

PMID:
17309838
24.

H2A.Z contributes to the unique 3D structure of the centromere.

Greaves IK, Rangasamy D, Ridgway P, Tremethick DJ.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):525-30. Epub 2006 Dec 28.

25.

Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.

Yang M, Rangasamy D, Matthaei KI, Frew AJ, Zimmmermann N, Mahalingam S, Webb DC, Tremethick DJ, Thompson PJ, Hogan SP, Rothenberg ME, Cowden WB, Foster PS.

J Immunol. 2006 Oct 15;177(8):5595-603.

26.

The X and Y chromosomes assemble into H2A.Z-containing [corrected] facultative heterochromatin [corrected] following meiosis.

Greaves IK, Rangasamy D, Devoy M, Marshall Graves JA, Tremethick DJ.

Mol Cell Biol. 2006 Jul;26(14):5394-405. Erratum in: Mol Cell Biol. 2006 Oct;26(19):7343.

27.

Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin.

Bulynko YA, Hsing LC, Mason RW, Tremethick DJ, Grigoryev SA.

Mol Cell Biol. 2006 Jun;26(11):4172-84.

28.

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken.

Bruce K, Myers FA, Mantouvalou E, Lefevre P, Greaves I, Bonifer C, Tremethick DJ, Thorne AW, Crane-Robinson C.

Nucleic Acids Res. 2005 Oct 4;33(17):5633-9. Print 2005.

29.

H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding.

Fan JY, Rangasamy D, Luger K, Tremethick DJ.

Mol Cell. 2004 Nov 19;16(4):655-61.

30.

Unique residues on the H2A.Z containing nucleosome surface are important for Xenopus laevis development.

Ridgway P, Brown KD, Rangasamy D, Svensson U, Tremethick DJ.

J Biol Chem. 2004 Oct 15;279(42):43815-20. Epub 2004 Aug 6.

31.

Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA.

Bao Y, Konesky K, Park YJ, Rosu S, Dyer PN, Rangasamy D, Tremethick DJ, Laybourn PJ, Luger K.

EMBO J. 2004 Aug 18;23(16):3314-24. Epub 2004 Jul 15.

32.

RNA interference demonstrates a novel role for H2A.Z in chromosome segregation.

Rangasamy D, Greaves I, Tremethick DJ.

Nat Struct Mol Biol. 2004 Jul;11(7):650-5. Epub 2004 Jun 13.

PMID:
15195148
33.
34.

Analysis of histone variant H2A.Z localization and expression during early development.

Ridgway P, Rangasamy D, Berven L, Svensson U, Tremethick DJ.

Methods Enzymol. 2004;375:239-52. No abstract available.

PMID:
14870671
35.

Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter.

Henderson A, Holloway A, Reeves R, Tremethick DJ.

Mol Cell Biol. 2004 Jan;24(1):389-97.

36.

Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development.

Rangasamy D, Berven L, Ridgway P, Tremethick DJ.

EMBO J. 2003 Apr 1;22(7):1599-607.

37.

The human IL-2 gene promoter can assemble a positioned nucleosome that becomes remodeled upon T cell activation.

Attema JL, Reeves R, Murray V, Levichkin I, Temple MD, Tremethick DJ, Shannon MF.

J Immunol. 2002 Sep 1;169(5):2466-76.

38.

The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states.

Fan JY, Gordon F, Luger K, Hansen JC, Tremethick DJ.

Nat Struct Biol. 2002 Mar;9(3):172-6. Erratum in: Nat Struct Biol 2002 Apr;9(4):316.

PMID:
11850638
39.

Histone variant H2A.Z is required for early mammalian development.

Faast R, Thonglairoam V, Schulz TC, Beall J, Wells JR, Taylor H, Matthaei K, Rathjen PD, Tremethick DJ, Lyons I.

Curr Biol. 2001 Aug 7;11(15):1183-7.

40.

Crystal structure of a nucleosome core particle containing the variant histone H2A.Z.

Suto RK, Clarkson MJ, Tremethick DJ, Luger K.

Nat Struct Biol. 2000 Dec;7(12):1121-4.

PMID:
11101893
41.
42.

Multiple ISWI ATPase complexes from xenopus laevis. Functional conservation of an ACF/CHRAC homolog.

Guschin D, Geiman TM, Kikyo N, Tremethick DJ, Wolffe AP, Wade PA.

J Biol Chem. 2000 Nov 10;275(45):35248-55.

43.

Preparation of chromatin assembly extracts from Xenopus oocytes.

Tremethick DJ.

Methods Mol Biol. 1999;119:175-86. Review. No abstract available.

PMID:
10804511
44.

Distinct importin recognition properties of histones and chromatin assembly factors.

Johnson-Saliba M, Siddon NA, Clarkson MJ, Tremethick DJ, Jans DA.

FEBS Lett. 2000 Feb 11;467(2-3):169-74.

45.

Regions of variant histone His2AvD required for Drosophila development.

Clarkson MJ, Wells JR, Gibson F, Saint R, Tremethick DJ.

Nature. 1999 Jun 17;399(6737):694-7.

PMID:
10385122
46.

Chromatin assembly in Xenopus extracts.

Tremethick DJ.

Methods Enzymol. 1999;304:50-63. No abstract available.

PMID:
10372355
47.

The binding of a Fos/Jun heterodimer can completely disrupt the structure of a nucleosome.

Ng KW, Ridgway P, Cohen DR, Tremethick DJ.

EMBO J. 1997 Apr 15;16(8):2072-85.

50.

High mobility group proteins 14 and 17 can space nucleosomes in vitro.

Tremethick DJ, Drew HR.

J Biol Chem. 1993 May 25;268(15):11389-93.

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