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Increased carotid artery wall stiffness and plaque prevalence in HIV infected patients measured with ultrasound elastography.

Roy Cardinal MH, Durand M, Chartrand-Lefebvre C, Fortin C, Baril JG, Trottier B, Routy JP, Soulez G, Tremblay C, Cloutier G.

Eur Radiol. 2020 Feb 12. doi: 10.1007/s00330-020-06660-9. [Epub ahead of print]


Is sharing really caring? Viewpoints on shared decision-making in paediatrics.

Jordan Z, Tremblay C, Lipstein E, Jordan I, Boland L.

J Paediatr Child Health. 2020 Feb 11. doi: 10.1111/jpc.14806. [Epub ahead of print]


Relative influence of watershed and geomorphic features on nutrient and carbon fluxes in a pristine and moderately urbanized stream.

Tremblay CC, Botrel M, Lapierre JF, Franssen J, Maranger R.

Sci Total Environ. 2020 Jan 11;715:136411. doi: 10.1016/j.scitotenv.2019.136411. [Epub ahead of print]


Brain mural cell loss in the parietal cortex in Alzheimer's disease correlates with cognitive decline and TDP-43 pathology.

Bourassa P, Tremblay C, Schneider JA, Bennett DA, Calon F.

Neuropathol Appl Neurobiol. 2020 Jan 22. doi: 10.1111/nan.12599. [Epub ahead of print]


Prevalence and incidence of HPV infection in men having sex with men enrolled in a PrEP study: A sub-study of the ANRS IPERGAY trial.

Cotte L, Veyer D, Charreau I, Péré H, Cua E, Carette D, Chas J, Capitant C, Chidiac C, Fléjou JF, Fouéré S, Heard I, Meyer L, Puech J, Tremblay C, Delaugerre C, Molina JM.

Clin Infect Dis. 2020 Jan 7. pii: ciaa002. doi: 10.1093/cid/ciaa002. [Epub ahead of print]


Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux.

Sandoz PA, Tremblay C, van der Goot FG, Frechin M.

PLoS Biol. 2019 Dec 19;17(12):e3000553. doi: 10.1371/journal.pbio.3000553. eCollection 2019 Dec.


Antibody-Dependent Cellular Cytotoxicity-Competent Antibodies against HIV-1-Infected Cells in Plasma from HIV-Infected Subjects.

Dupuy FP, Kant S, Barbé A, Routy JP, Bruneau J, Lebouché B, Tremblay C, Pazgier M, Finzi A, Bernard NF.

mBio. 2019 Dec 17;10(6). pii: e02690-19. doi: 10.1128/mBio.02690-19.


Early diagnosis and risk factors of acute hepatitis C in high-risk MSM on preexposure prophylaxis.

Gras J, Mahjoub N, Charreau I, Cotte L, Tremblay C, Chas J, Raffi F, Cua E, Guillon B, Guigue N, Chaix ML, Meyer L, Molina JM, Delaugerre C; IPERGAY Study Group.

AIDS. 2020 Jan 1;34(1):47-52. doi: 10.1097/QAD.0000000000002364.


On-demand pre-exposure prophylaxis with tenofovir disoproxil fumarate plus emtricitabine among men who have sex with men with less frequent sexual intercourse: a post-hoc analysis of the ANRS IPERGAY trial.

Antoni G, Tremblay C, Delaugerre C, Charreau I, Cua E, Rojas Castro D, Raffi F, Chas J, Huleux T, Spire B, Capitant C, Cotte L, Meyer L, Molina JM; ANRS IPERGAY study group.

Lancet HIV. 2020 Feb;7(2):e113-e120. doi: 10.1016/S2352-3018(19)30341-8. Epub 2019 Nov 26.


Attenuated Acceleration to Leukemia after Ezh2 Loss in Nup98-HoxD13 (NHD13) Myelodysplastic Syndrome.

Ling VY, Saw J, Tremblay CS, Sonderegger SE, Toulmin E, Boyle J, Chiu SK, Lane SW, Ting SB, Curtis DJ.

Hemasphere. 2019 Aug 7;3(4):e277. doi: 10.1097/HS9.0000000000000277. eCollection 2019 Aug.


Despite early antiretroviral therapy effector memory and follicular helper CD4 T cells are major reservoirs in visceral lymphoid tissues of SIV-infected macaques.

Rabezanahary H, Moukambi F, Palesch D, Clain J, Racine G, Andreani G, Benmadid-Laktout G, Zghidi-Abouzid O, Soundaramourty C, Tremblay C, Silvestri G, Estaquier J.

Mucosal Immunol. 2020 Jan;13(1):149-160. doi: 10.1038/s41385-019-0221-x. Epub 2019 Nov 13.


Upregulation of IL-32 Isoforms in Virologically Suppressed HIV-Infected Individuals: Potential Role in Persistent Inflammation and Transcription From Stable HIV-1 Reservoirs.

Zaidan SM, Leyre L, Bunet R, Larouche-Anctil E, Turcotte I, Sylla M, Chamberland A, Chartrand-Lefebvre C, Ancuta P, Routy JP, Baril JG, Trottier B, MacPherson P, Trottier S, Harris M, Walmsley S, Conway B, Wong A, Thomas R, Kaplan RC, Landay AL, Durand M, Chomont N, Tremblay CL, El-Far M; Canadian HIV and Aging Cohort Study.

J Acquir Immune Defic Syndr. 2019 Dec 15;82(5):503-513. doi: 10.1097/QAI.0000000000002185.


HIV-1 Envelope Glycoprotein Amino Acids Signatures Associated with Clade B Transmitted/Founder and Recent Viruses.

Kafando A, Martineau C, El-Far M, Fournier E, Doualla-Bell F, Serhir B, Kazienga A, Sangaré MN, Sylla M, Chamberland A, Charest H, Tremblay CL.

Viruses. 2019 Nov 1;11(11). pii: E1012. doi: 10.3390/v11111012.


Incidence of Venous Thromboembolism in Patients Living with HIV: A Cohort Study.

Durand M, Sinyavskaya L, Jin YL, Tremblay CL, Ducruet T, Laskine M.

AIDS Patient Care STDS. 2019 Nov;33(11):455-458. doi: 10.1089/apc.2019.0154. No abstract available.


CMV seropositivity is associated with increased microbial translocation in people living with HIV and uninfected controls.

Ramendra R, Isnard S, Lin J, Fombuena B, Ouyang J, Mehraj V, Zhang Y, Finkelman M, Costiniuk C, Lebouché B, Chartrand-Lefebvre C, Durand M, Tremblay C, Ancuta P, Boivin G, Routy JP.

Clin Infect Dis. 2019 Oct 14. pii: ciz1001. doi: 10.1093/cid/ciz1001. [Epub ahead of print]


Association between lipodystrophy and length of exposure to ARTs in adult HIV-1 infected patients in Montreal.

Alikhani A, Morin H, Matte S, Alikhani P, Tremblay C, Durand M.

BMC Infect Dis. 2019 Sep 18;19(1):820. doi: 10.1186/s12879-019-4446-9.


Plasma Levels of C-Type Lectin REG3α and Gut Damage in People With Human Immunodeficiency Virus.

Isnard S, Ramendra R, Dupuy FP, Lin J, Fombuena B, Kokinov N, Kema I, Jenabian MA, Lebouché B, Costiniuk CT, Ancuta P, Bernard NF, Silverman MS, Lakatos PL, Durand M, Tremblay C, Routy JP; Montreal Primary HIV Infection Study, the Canadian Cohort of HIV+ Slow Progressors, and the Canadian HIV and Aging Cohort Groups .

J Infect Dis. 2020 Jan 1;221(1):110-121. doi: 10.1093/infdis/jiz423.


Early diagnosis and risk factors of acute hepatitis c in high-risk men who have sex with men on pre-exposure prophylaxis.

Gras J, Mahjoub N, Charreau I, Cotte L, Tremblay C, Chas J, Raffi F, Cua E, Guillon B, Guigue N, Chaix ML, Meyer L, Molina JM, Delaugerre C; and the Ipergay study group.

AIDS. 2019 Sep 2. doi: 10.1097/QAD.0000000000002364. [Epub ahead of print]


Specific intranasal and central trigeminal electrophysiological responses in Parkinson's disease.

Tremblay C, Emrich R, Cavazzana A, Klingelhoefer L, Brandt MD, Hummel T, Haehner A, Frasnelli J.

J Neurol. 2019 Dec;266(12):2942-2951. doi: 10.1007/s00415-019-09517-4. Epub 2019 Aug 26.


A Short-Term Assessment of Nascent HIV-1 Transmission Clusters Among Newly Diagnosed Individuals Using Envelope Sequence-Based Phylogenetic Analyses.

Kafando A, Serhir B, Doualla-Bell F, Fournier E, Sangaré MN, Martineau C, Sylla M, Chamberland A, El-Far M, Charest H, Tremblay CL.

AIDS Res Hum Retroviruses. 2019 Oct;35(10):906-919. doi: 10.1089/AID.2019.0142. Epub 2019 Sep 10.


Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease.

Morou A, Brunet-Ratnasingham E, Dubé M, Charlebois R, Mercier E, Darko S, Brassard N, Nganou-Makamdop K, Arumugam S, Gendron-Lepage G, Yang L, Niessl J, Baxter AE, Billingsley JM, Rajakumar PA, Lefebvre F, Johnson RP, Tremblay C, Routy JP, Wyatt RT, Finzi A, Douek DC, Kaufmann DE.

Nat Immunol. 2019 Aug;20(8):1059-1070. doi: 10.1038/s41590-019-0418-x. Epub 2019 Jul 15.


Shared roles for Scl and Lyl1 in murine platelet production and function.

Chiu SK, Orive SL, Moon MJ, Saw J, Ellis S, Kile BT, Huang Y, Chacon D, Pimanda JE, Beck D, Hamilton JR, Tremblay CS, Curtis DJ.

Blood. 2019 Sep 5;134(10):826-835. doi: 10.1182/blood.2019896175. Epub 2019 Jul 12.


Magnetic Resonance Navigation for Targeted Embolization in a Two-Level Bifurcation Phantom.

Li N, Jiang Y, Plantefève R, Michaud F, Nosrati Z, Tremblay C, Saatchi K, Häfeli UO, Kadoury S, Moran G, Joly F, Martel S, Soulez G.

Ann Biomed Eng. 2019 Dec;47(12):2402-2415. doi: 10.1007/s10439-019-02317-x. Epub 2019 Jul 9.


50 to 30-Hz triplet and singlet down sweep vocalizations produced by sei whales (Balaenoptera borealis) in the western North Atlantic Ocean.

Tremblay CJ, Van Parijs SM, Cholewiak D.

J Acoust Soc Am. 2019 Jun;145(6):3351. doi: 10.1121/1.5110713.


The anti-inflammatory IL-37/SIGIRR axis is functionally compromised in HIV infection.

Samarani S, Abulkhir A, Amre D, Mehraj V, Tremblay C, Routy JP, Ahmad A.

AIDS. 2019 Sep 1;33(11):1693-1703. doi: 10.1097/QAD.0000000000002271.


Quantifying Anti-HIV Envelope-Specific Antibodies in Plasma from HIV Infected Individuals.

Kant S, Zhang N, Routy JP, Tremblay C, Thomas R, Szabo J, Côté P, Trottier B, LeBlanc R, Rouleau D, Harris M, Dupuy FP, Bernard NF.

Viruses. 2019 May 28;11(6). pii: E487. doi: 10.3390/v11060487.


The autonomic nervous system regulates pancreatic β-cell proliferation in adult male rats.

Moullé VS, Tremblay C, Castell AL, Vivot K, Ethier M, Fergusson G, Alquier T, Ghislain J, Poitout V.

Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E234-E243. doi: 10.1152/ajpendo.00385.2018. Epub 2019 Apr 23.


Changes in vascular accesses and in incidence rates of dialysis-related bloodstream infections in Québec, Canada, 2011-2017.

Fortin É, Ouakki M, Tremblay C, Villeneuve J, Desmeules S, Parisien N, Moisan D, Frenette C; for SPIN-BAC-HD.

Infect Control Hosp Epidemiol. 2019 Jun;40(6):627-631. doi: 10.1017/ice.2019.65. Epub 2019 Apr 8.


Evaluation of the Bio-Rad Geenius HIV 1/2 Assay as Part of a Confirmatory HIV Testing Strategy for Quebec, Canada: Comparison with Western Blot and Inno-Lia Assays.

Serhir B, Desjardins C, Doualla-Bell F, Simard M, Tremblay C, Longtin J.

J Clin Microbiol. 2019 May 24;57(6). pii: e01398-18. doi: 10.1128/JCM.01398-18. Print 2019 Jun.


In-depth Sampling of High-risk Populations to Characterize HIV Transmission Epidemics Among Young MSM Using PrEP in France and Quebec.

Chaillon A, Delaugerre C, Brenner B, Armero A, Capitant C, Nere ML, Leturque N, Pialoux G, Cua E, Tremblay C, Smith DM, Goujard C, Meyer L, Molina JM, Chaix ML.

Open Forum Infect Dis. 2019 Feb 15;6(3):ofz080. doi: 10.1093/ofid/ofz080. eCollection 2019 Mar.


Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy.

Beaulieu ME, Jauset T, Massó-Vallés D, Martínez-Martín S, Rahl P, Maltais L, Zacarias-Fluck MF, Casacuberta-Serra S, Serrano Del Pozo E, Fiore C, Foradada L, Cano VC, Sánchez-Hervás M, Guenther M, Romero Sanz E, Oteo M, Tremblay C, Martín G, Letourneau D, Montagne M, Morcillo Alonso MÁ, Whitfield JR, Lavigne P, Soucek L.

Sci Transl Med. 2019 Mar 20;11(484). pii: eaar5012. doi: 10.1126/scitranslmed.aar5012.


Healthcare-associated bloodstream infection trends under a provincial surveillance program.

Fakih I, Fortin É, Smith MA, Carignan A, Tremblay C, Villeneuve J, Moisan D, Frenette C, Quach C, Schmidt AM; for SPIN-BACTOT.

Infect Control Hosp Epidemiol. 2019 Mar;40(3):307-313. doi: 10.1017/ice.2018.357.


Circulating (1→3)-β-D-glucan Is Associated With Immune Activation During Human Immunodeficiency Virus Infection.

Mehraj V, Ramendra R, Isnard S, Dupuy FP, Ponte R, Chen J, Kema I, Jenabian MA, Costinuik CT, Lebouché B, Thomas R, Coté P, Leblanc R, Baril JG, Durand M, Chartrand-Lefebvre C, Tremblay C, Ancuta P, Bernard NF, Sheppard DC, Routy JP; Montreal Primary HIV Infection Study and Canadian HIV and Aging Cohort Study Groups .

Clin Infect Dis. 2020 Jan 2;70(2):232-241. doi: 10.1093/cid/ciz212.


CXCL13 as a Biomarker of Immune Activation During Early and Chronic HIV Infection.

Mehraj V, Ramendra R, Isnard S, Dupuy FP, Lebouché B, Costiniuk C, Thomas R, Szabo J, Baril JG, Trottier B, Coté P, LeBlanc R, Durand M, Chartrand-Lefebvre C, Kema I, Zhang Y, Finkelman M, Tremblay C, Routy JP.

Front Immunol. 2019 Feb 21;10:289. doi: 10.3389/fimmu.2019.00289. eCollection 2019.


Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer's disease.

Bourassa P, Tremblay C, Schneider JA, Bennett DA, Calon F.

Acta Neuropathol. 2019 May;137(5):801-823. doi: 10.1007/s00401-019-01967-4. Epub 2019 Feb 7.


ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.

Goossens S, Wang J, Tremblay CS, De Medts J, T'Sas S, Nguyen T, Saw J, Haigh K, Curtis DJ, Van Vlierberghe P, Berx G, Taghon T, Haigh JJ.

Haematologica. 2019 Aug;104(8):1608-1616. doi: 10.3324/haematol.2018.207837. Epub 2019 Jan 24.


Transferrin Receptor-Mediated Uptake at the Blood-Brain Barrier Is Not Impaired by Alzheimer's Disease Neuropathology.

Bourassa P, Alata W, Tremblay C, Paris-Robidas S, Calon F.

Mol Pharm. 2019 Feb 4;16(2):583-594. doi: 10.1021/acs.molpharmaceut.8b00870. Epub 2019 Jan 17.


MRI-Compatible Injection System for Magnetic Microparticle Embolization.

Li N, Michaud F, Nosrati Z, Loghin D, Tremblay C, Plantefeve R, Saatchi K, Hafeli UO, Martel S, Soulez G.

IEEE Trans Biomed Eng. 2019 Aug;66(8):2331-2340. doi: 10.1109/TBME.2018.2889000. Epub 2018 Dec 20.


Dietary intake of branched-chain amino acids in a mouse model of Alzheimer's disease: Effects on survival, behavior, and neuropathology.

Tournissac M, Vandal M, Tremblay C, Bourassa P, Vancassel S, Emond V, Gangloff A, Calon F.

Alzheimers Dement (N Y). 2018 Dec 10;4:677-687. doi: 10.1016/j.trci.2018.10.005. eCollection 2018.


Effect of On-Demand Oral Pre-exposure Prophylaxis With Tenofovir/Emtricitabine on Herpes Simplex Virus-1/2 Incidence Among Men Who Have Sex With Men: A Substudy of the ANRS IPERGAY Trial.

Chaix ML, Charreau I, Pintado C, Delaugerre C, Mahjoub N, Cotte L, Capitant C, Raffi F, Cua E, Pialoux G, Tremblay C, Meyer L, Molina JM; ANRS IPERGAY Study Group .

Open Forum Infect Dis. 2018 Nov 8;5(11):ofy295. doi: 10.1093/ofid/ofy295. eCollection 2018 Nov.


Selective embolization with magnetized microbeads using magnetic resonance navigation in a controlled-flow liver model.

Michaud F, Li N, Plantefève R, Nosrati Z, Tremblay C, Saatchi K, Moran G, Bigot A, Häfeli UO, Kadoury S, Tang A, Perreault P, Martel S, Soulez G.

Med Phys. 2019 Feb;46(2):789-799. doi: 10.1002/mp.13298. Epub 2018 Dec 17.


HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state.

Merindol N, El-Far M, Sylla M, Masroori N, Dufour C, Li JX, Cherry P, Plourde MB, Tremblay C, Berthoux L.

PLoS Pathog. 2018 Nov 12;14(11):e1007398. doi: 10.1371/journal.ppat.1007398. eCollection 2018 Nov.


CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features.

Wacleche VS, Cattin A, Goulet JP, Gauchat D, Gosselin A, Cleret-Buhot A, Zhang Y, Tremblay CL, Routy JP, Ancuta P.

Blood Adv. 2018 Nov 13;2(21):2862-2878. doi: 10.1182/bloodadvances.2018020123.


Improvement of reverse sequence algorithm for syphilis diagnosis using optimal treponemal screening assay signal-to-cutoff ratio.

Serhir B, Labbé AC, Doualla-Bell F, Simard M, Lambert G, Trudelle A, Longtin J, Tremblay C, Fortin C.

PLoS One. 2018 Sep 13;13(9):e0204001. doi: 10.1371/journal.pone.0204001. eCollection 2018.


Is on-Demand HIV Pre-exposure Prophylaxis a Suitable Tool for Men Who Have Sex With Men Who Practice Chemsex? Results From a Substudy of the ANRS-IPERGAY Trial.

Roux P, Fressard L, Suzan-Monti M, Chas J, Sagaon-Teyssier L, Capitant C, Meyer L, Tremblay C, Rojas-Castro D, Pialoux G, Molina JM, Spire B.

J Acquir Immune Defic Syndr. 2018 Oct 1;79(2):e69-e75. doi: 10.1097/QAI.0000000000001781.


A novel role for Lyl1 in primitive erythropoiesis.

Chiu SK, Saw J, Huang Y, Sonderegger SE, Wong NC, Powell DR, Beck D, Pimanda JE, Tremblay CS, Curtis DJ.

Development. 2018 Oct 11;145(19). pii: dev162990. doi: 10.1242/dev.162990.


Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells.

Tremblay CS, Saw J, Chiu SK, Wong NC, Tsyganov K, Ghotb S, Graham AN, Yan F, Guirguis AA, Sonderegger SE, Lee N, Kalitsis P, Reynolds J, Ting SB, Powell DR, Jane SM, Curtis DJ.

Nat Commun. 2018 Aug 30;9(1):3535. doi: 10.1038/s41467-018-06021-7.


A ten-year review of healthcare-associated bloodstream infections from forty hospitals in Québec, Canada.

Fakih I, Fortin É, Smith MA, Carignan A, Tremblay C, Villeneuve J, Moisan D, Frenette C, Quach C; for SPIN-BACTOT.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1202-1209. doi: 10.1017/ice.2018.185. Epub 2018 Aug 29.


Chemosensory perception is specifically impaired in Parkinson's disease.

Tremblay C, Durand Martel P, Frasnelli J.

Parkinsonism Relat Disord. 2018 Dec;57:68-71. doi: 10.1016/j.parkreldis.2018.08.002. Epub 2018 Aug 6.


Olfactory and Trigeminal Systems Interact in the Periphery.

Tremblay C, Frasnelli J.

Chem Senses. 2018 Sep 22;43(8):611-616. doi: 10.1093/chemse/bjy049.


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