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Items: 1 to 50 of 116

1.

The human urothelial tight junction: claudin 3 and the ZO-1α+ switch.

Smith NJ, Hinley J, Varley CL, Eardley I, Trejdosiewicz LK, Southgate J.

Bladder (San Franc). 2015;2(1):e9.

2.

Differentiation-associated reprogramming of the transforming growth factor β receptor pathway establishes the circuitry for epithelial autocrine/paracrine repair.

Fleming JM, Shabir S, Varley CL, Kirkwood LA, White A, Holder J, Trejdosiewicz LK, Southgate J.

PLoS One. 2012;7(12):e51404. doi: 10.1371/journal.pone.0051404. Epub 2012 Dec 19.

3.

Toll-like receptor responses of normal human urothelial cells to bacterial flagellin and lipopolysaccharide.

Smith NJ, Varley CL, Eardley I, Feather S, Trejdosiewicz LK, Southgate J.

J Urol. 2011 Sep;186(3):1084-92. doi: 10.1016/j.juro.2011.04.112. Epub 2011 Jul 23.

PMID:
21784459
4.

Differentiation potential of urothelium from patients with benign bladder dysfunction.

Southgate J, Varley CL, Garthwaite MA, Hinley J, Marsh F, Stahlschmidt J, Trejdosiewicz LK, Eardley I.

BJU Int. 2007 Jun;99(6):1506-16.

5.

CD40-mediated death and cytokine secretion in colorectal cancer: a potential target for inflammatory tumour cell killing.

Georgopoulos NT, Merrick A, Scott N, Selby PJ, Melcher A, Trejdosiewicz LK.

Int J Cancer. 2007 Sep 15;121(6):1373-81.

6.

PPARgamma-regulated tight junction development during human urothelial cytodifferentiation.

Varley CL, Garthwaite MA, Cross W, Hinley J, Trejdosiewicz LK, Southgate J.

J Cell Physiol. 2006 Aug;208(2):407-17.

7.

A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation.

Georgopoulos NT, Steele LP, Thomson MJ, Selby PJ, Southgate J, Trejdosiewicz LK.

Cell Death Differ. 2006 Oct;13(10):1789-801. Epub 2006 Jan 20.

8.

Differential susceptibility to TRAIL of normal versus malignant human urothelial cells.

Steele LP, Georgopoulos NT, Southgate J, Selby PJ, Trejdosiewicz LK.

Cell Death Differ. 2006 Sep;13(9):1564-76. Epub 2006 Jan 13.

9.

Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro.

Varley C, Hill G, Pellegrin S, Shaw NJ, Selby PJ, Trejdosiewicz LK, Southgate J.

Exp Cell Res. 2005 May 15;306(1):216-29.

PMID:
15878346
10.

Effects of loss of p53 and p16 function on life span and survival of human urothelial cells.

Shaw NJ, Georgopoulos NT, Southgate J, Trejdosiewicz LK.

Int J Cancer. 2005 Sep 10;116(4):634-9.

11.

Urothelial cell transplantation using biodegradable synthetic scaffolds.

Scriven SD, Trejdosiewicz LK, Thomas DF, Southgate J.

J Mater Sci Mater Med. 2001 Oct-Dec;12(10-12):991-6.

PMID:
15348353
12.

Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme.

Varley CL, Stahlschmidt J, Lee WC, Holder J, Diggle C, Selby PJ, Trejdosiewicz LK, Southgate J.

J Cell Sci. 2004 Apr 15;117(Pt 10):2029-36. Epub 2004 Mar 30.

13.

A surgical model of composite cystoplasty with cultured urothelial cells: a controlled study of gross outcome and urothelial phenotype.

Fraser M, Thomas DF, Pitt E, Harnden P, Trejdosiewicz LK, Southgate J.

BJU Int. 2004 Mar;93(4):609-16.

14.

Bladder reconstruction--from cells to materials.

Southgate J, Cross W, Eardley I, Thomas DF, Trejdosiewicz LK.

Proc Inst Mech Eng H. 2003;217(4):311-6. Review.

PMID:
12885202
15.

The effects of malignant transformation on susceptibility of human urothelial cells to CD40-mediated apoptosis.

Bugajska U, Georgopoulos NT, Southgate J, Johnson PW, Graber P, Gordon J, Selby PJ, Trejdosiewicz LK.

J Natl Cancer Inst. 2002 Sep 18;94(18):1381-95.

PMID:
12237284
16.

Normal human liver organ culture.

Cruickshank SM, Southgate J, Trejdosiewicz LK.

In Vitro Cell Dev Biol Anim. 2001 Apr;37(4):231-3. No abstract available.

PMID:
11409688
17.

Role of p53 in the responses of human urothelial cells to genotoxic damage.

Diggle CP, Pitt E, Harnden P, Trejdosiewicz LK, Southgate J.

Int J Cancer. 2001 Jul 15;93(2):199-203.

18.

Transforming growth factor-beta promotes 'death by neglect' in post-activated human T cells.

Sillett HK, Cruickshank SM, Southgate J, Trejdosiewicz LK.

Immunology. 2001 Mar;102(3):310-6.

19.

Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium.

Smith BA, Kennedy WJ, Harnden P, Selby PJ, Trejdosiewicz LK, Southgate J.

Cancer Res. 2001 Feb 15;61(4):1678-85.

20.

N;-3 and n;-6 polyunsaturated fatty acids induce cytostasis in human urothelial cells independent of p53 gene function.

Diggle CP, Pitt E, Roberts P, Trejdosiewicz LK, Southgate J.

J Lipid Res. 2000 Sep;41(9):1509-15.

21.

Effects of long-chain fatty acids on human urothelial cells in organ culture.

Diggle CP, Pitt E, Trejdosiewicz LK, Southgate J.

Prostaglandins Leukot Essent Fatty Acids. 2000 Apr;62(4):249-52.

PMID:
10882190
22.

Subcutaneous administration of recombinant glycosylated interleukin 6 in patients with cancer: pharmacokinetics, pharmacodynamics and immunomodulatory effects.

Banks RE, Forbes MA, Patel PM, Storr M, Hallam S, Clarke D, Novick D, Ingham E, Bowmer C, Southgate J, Trejdosiewicz LK, Illingworth J, Perren TJ, Selby PJ.

Cytokine. 2000 Apr;12(4):388-96.

PMID:
10805221
23.

Expression of CD44 on bile ducts in primary sclerosing cholangitis and primary biliary cirrhosis.

Cruickshank SM, Southgate J, Wyatt JI, Selby PJ, Trejdosiewicz LK.

J Clin Pathol. 1999 Oct;52(10):730-4.

24.

Inhibition of T cell activation by normal human biliary epithelial cells.

Cruickshank SM, Southgate J, Selby PJ, Trejdosiewicz LK.

J Hepatol. 1999 Dec;31(6):1026-33.

PMID:
10604576
25.

The role of matrix metalloproteinases in an in vitro model of bladder tumor invasion.

Booth C, Harnden P, Selby PJ, Trejdosiewicz LK, Southgate J.

Adv Exp Med Biol. 1999;462:413-7. No abstract available.

PMID:
10599443
26.

Reconstruction of the urinary bladder by auto-augmentation, enterocystoplasty, and composite enterocystoplasty.

Comer MT, Thomas DF, Trejdosiewicz LK, Southgate J.

Adv Exp Med Biol. 1999;462:43-7. Review. No abstract available.

PMID:
10599412
27.

Urothelial tissue regulation. Unraveling the role of the stroma.

Southgate J, Harnden P, Selby PJ, Thomas DF, Trejdosiewicz LK.

Adv Exp Med Biol. 1999;462:19-30. Review. No abstract available.

PMID:
10599410
28.

Application of a marker of ciliated epithelial cells to gynaecological pathology.

Comer MT, Andrew AC, Leese HJ, Trejdosiewicz LK, Southgate J.

J Clin Pathol. 1999 May;52(5):355-7.

29.

Expression of an antigen associated with basal bodies of human ciliated epithelial cells.

Comer MT, Shires M, Goode NP, Leese HJ, Trejdosiewicz LK, Southgate J.

Histochem J. 1999 Jan;31(1):39-43.

PMID:
10405821
30.

Expression of activation and costimulatory elements by human intestinal intraepithelial lymphocytes.

Sillett HK, Southgate J, Howdle PD, Trejdosiewicz LK.

Scand J Immunol. 1999 Jul;50(1):52-60.

31.

Cytokeratin expression patterns in normal and malignant urothelium: a review of the biological and diagnostic implications.

Southgate J, Harnden P, Trejdosiewicz LK.

Histol Histopathol. 1999 Apr;14(2):657-64. doi: 10.14670/HH-14.657. Review.

PMID:
10212826
32.

Uroplakin gene expression by normal and neoplastic human urothelium.

Lobban ED, Smith BA, Hall GD, Harnden P, Roberts P, Selby PJ, Trejdosiewicz LK, Southgate J.

Am J Pathol. 1998 Dec;153(6):1957-67.

33.
34.

Effects of resuscitation fluids on T cell immune responses.

Sillett HK, Whicher JT, Trejdosiewicz LK.

Br J Anaesth. 1998 Aug;81(2):242-3.

35.

Interleukins 4 and 13 upregulate expression of cd44 in human colonic epithelial cell lines.

Trejdosiewicz LK, Morton R, Yang Y, Banks RE, Selby PJ, Southgate J.

Cytokine. 1998 Oct;10(10):756-65.

PMID:
9811528
36.

Culture of ascitic ovarian cancer cells as a clinically-relevant ex vivo model for the assessment of biological therapies.

Metcalf KS, Selby PJ, Trejdosiewicz LK, Southgate J.

Eur J Gynaecol Oncol. 1998;19(2):113-9.

PMID:
9611047
37.

Effects of resuscitation fluids on nonadaptive immune responses.

Sillett HK, Whicher JT, Trejdosiewicz LK.

Transfusion. 1997 Sep;37(9):953-9.

PMID:
9308644
38.

Reconstitution of human urothelium from monolayer cultures.

Scriven SD, Booth C, Thomas DF, Trejdosiewicz LK, Southgate J.

J Urol. 1997 Sep;158(3 Pt 2):1147-52.

PMID:
9258159
39.

Stromal and vascular invasion in an human in vitro bladder cancer model.

Booth C, Harnden P, Trejdosiewicz LK, Scriven S, Selby PJ, Southgate J.

Lab Invest. 1997 Jun;76(6):843-57.

PMID:
9194860
40.

The effects of dietary fatty acids on the proliferation of normal human urothelial cells in vitro.

Southgate J, Pitt E, Trejdosiewicz LK.

Br J Cancer. 1996 Sep;74(5):728-34.

41.

Peripheral cell-mediated immune response to mycobacterial antigens in inflammatory bowel disease.

Rowbotham DS, Howdle PD, Trejdosiewicz LK.

Clin Exp Immunol. 1995 Dec;102(3):456-61.

42.

Mycobacterium paratuberculosis DNA not detected in Crohn's disease tissue by fluorescent polymerase chain reaction.

Rowbotham DS, Mapstone NP, Trejdosiewicz LK, Howdle PD, Quirke P.

Gut. 1995 Nov;37(5):660-7.

43.

Patterns of splice variant CD44 expression by normal human urothelium in situ and in vitro and by bladder-carcinoma cell lines.

Southgate J, Trejdosiewicz LK, Smith B, Selby PJ.

Int J Cancer. 1995 Aug 9;62(4):449-56.

PMID:
7543458
44.

Expression and in vitro regulation of integrins by normal human urothelial cells.

Southgate J, Kennedy W, Hutton KA, Trejdosiewicz LK.

Cell Adhes Commun. 1995 Aug;3(3):231-42.

PMID:
8846024
45.

Gastrointestinal intra-epithelial lymphocytes in man: the saga continues.

Trejdosiewicz LK, Crabtree JE.

Eur J Gastroenterol Hepatol. 1995 Jun;7(6):537-40. Review. No abstract available.

PMID:
7552636
46.

T-cell responses and cellular immunity in coeliac disease.

Trejdosiewicz LK, Howdle PD.

Baillieres Clin Gastroenterol. 1995 Jun;9(2):251-72. Review.

PMID:
7549027
47.

Normal human urothelial cells in vitro: proliferation and induction of stratification.

Southgate J, Hutton KA, Thomas DF, Trejdosiewicz LK.

Lab Invest. 1994 Oct;71(4):583-94.

PMID:
7967513
48.

Mucosal interleukin-6 secretion in ulcerative colitis. Effects of anti-inflammatory drugs and T-cell stimulation.

Jones SC, Crabtree JE, Rembacken BJ, Dixon MF, Trejdosiewicz LK, Whicher JT, Axon AT.

Scand J Gastroenterol. 1994 Aug;29(8):722-8.

PMID:
7973432
49.

Interleukin-8 expression in Helicobacter pylori infected, normal, and neoplastic gastroduodenal mucosa.

Crabtree JE, Wyatt JI, Trejdosiewicz LK, Peichl P, Nichols PH, Ramsay N, Primrose JN, Lindley IJ.

J Clin Pathol. 1994 Jan;47(1):61-6.

50.

Expression of interleukin-6 by intestinal enterocytes.

Jones SC, Trejdosiewicz LK, Banks RE, Howdle PD, Axon AT, Dixon MF, Whicher JT.

J Clin Pathol. 1993 Dec;46(12):1097-100.

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