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Items: 1 to 50 of 279

1.

Evidence that blunted CD4 T cells responses underlie deficient protective antibody responses to influenza vaccines in repeatedly vaccinated human subjects.

Richards KA, Shannon I, Treanor JJ, Yang H, Nayak JL, Sant AJ.

J Infect Dis. 2019 Aug 26. pii: jiz433. doi: 10.1093/infdis/jiz433. [Epub ahead of print]

PMID:
31504634
2.

Monoclonal antibody responses after recombinant HA vaccine versus subunit inactivated influenza virus vaccine: a comparative study.

Henry C, Palm AE, Utset HA, Huang M, Ho IY, Zheng NY, Fitzgerald T, Neu KE, Chen YQ, Krammer F, Treanor JJ, Sant AJ, Topham DJ, Wilson PC.

J Virol. 2019 Aug 21. pii: JVI.01150-19. doi: 10.1128/JVI.01150-19. [Epub ahead of print]

PMID:
31434733
3.

Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans.

Khurana S, Hahn M, Coyle EM, King LR, Lin TL, Treanor J, Sant A, Golding H.

Nat Commun. 2019 Jul 26;10(1):3338. doi: 10.1038/s41467-019-11296-5.

4.

Continuous Readout versus Titer-Based Assays of Influenza Vaccine Trials: Sensitivity, Specificity, and False Discovery Rates.

Li D, Wang J, Garigen J, Treanor JJ, Zand MS.

Comput Math Methods Med. 2019 May 8;2019:9287120. doi: 10.1155/2019/9287120. eCollection 2019.

5.

Improved Specificity and False Discovery Rates for Multiplex Analysis of Changes in Strain-Specific Anti-Influenza IgG.

Li D, Wang J, Treanor JJ, Zand MS.

Comput Math Methods Med. 2019 Apr 15;2019:3053869. doi: 10.1155/2019/3053869. eCollection 2019.

6.

Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.

Henry C, Zheng NY, Huang M, Cabanov A, Rojas KT, Kaur K, Andrews SF, Palm AE, Chen YQ, Li Y, Hoskova K, Utset HA, Vieira MC, Wrammert J, Ahmed R, Holden-Wiltse J, Topham DJ, Treanor JJ, Ertl HC, Schmader KE, Cobey S, Krammer F, Hensley SE, Greenberg H, He XS, Wilson PC.

Cell Host Microbe. 2019 Mar 13;25(3):357-366.e6. doi: 10.1016/j.chom.2019.01.002. Epub 2019 Feb 19.

PMID:
30795982
7.

Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus.

Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, Ahmed R, Treanor JJ, Martinez-Sobrido L, Golding H, Khurana S, Zand MS, Topham DJ, Sangster MY.

J Virol. 2019 Apr 3;93(8). pii: e00169-19. doi: 10.1128/JVI.00169-19. Print 2019 Apr 15.

8.

Differences in the influenza-specific CD4 T cell immunodominance hierarchy and functional potential between children and young adults.

Shannon I, White CL, Murphy A, Qiu X, Treanor JJ, Nayak JL.

Sci Rep. 2019 Jan 28;9(1):791. doi: 10.1038/s41598-018-37167-5.

9.

First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1.

Stephenson KE, Keefer MC, Bunce CA, Frances D, Abbink P, Maxfield LF, Neubauer GH, Nkolola J, Peter L, Lane C, Park H, Verlinde C, Lombardo A, Yallop C, Havenga M, Fast P, Treanor J, Barouch DH.

PLoS One. 2018 Nov 14;13(11):e0205139. doi: 10.1371/journal.pone.0205139. eCollection 2018.

10.

Influenza Challenge and the Challenge of Drug Development.

Treanor J.

J Infect Dis. 2019 Jan 7;219(2):171-172. doi: 10.1093/infdis/jiy413. No abstract available.

PMID:
30053040
11.

Influenza.

Krammer F, Smith GJD, Fouchier RAM, Peiris M, Kedzierska K, Doherty PC, Palese P, Shaw ML, Treanor J, Webster RG, García-Sastre A.

Nat Rev Dis Primers. 2018 Jun 28;4(1):3. doi: 10.1038/s41572-018-0002-y. Review. No abstract available.

PMID:
29955068
12.
13.

Population Serologic Immunity to Human and Avian H2N2 Viruses in the United States and Hong Kong for Pandemic Risk Assessment.

Babu TM, Perera RAPM, Wu JT, Fitzgerald T, Nolan C, Cowling BJ, Krauss S, Treanor JJ, Peiris M.

J Infect Dis. 2018 Aug 24;218(7):1054-1060. doi: 10.1093/infdis/jiy291.

14.

What Happens Next Depends on What Happened First.

Treanor J.

Clin Infect Dis. 2018 Oct 30;67(10):1533-1534. doi: 10.1093/cid/ciy330. No abstract available.

PMID:
29672677
15.

Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.

Wang J, Hilchey SP, DeDiego M, Perry S, Hyrien O, Nogales A, Garigen J, Amanat F, Huertas N, Krammer F, Martinez-Sobrido L, Topham DJ, Treanor JJ, Sangster MY, Zand MS.

PLoS One. 2018 Apr 11;13(4):e0193680. doi: 10.1371/journal.pone.0193680. eCollection 2018.

16.

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies.

Chen YQ, Wohlbold TJ, Zheng NY, Huang M, Huang Y, Neu KE, Lee J, Wan H, Rojas KT, Kirkpatrick E, Henry C, Palm AE, Stamper CT, Lan LY, Topham DJ, Treanor J, Wrammert J, Ahmed R, Eichelberger MC, Georgiou G, Krammer F, Wilson PC.

Cell. 2018 Apr 5;173(2):417-429.e10. doi: 10.1016/j.cell.2018.03.030.

17.

Safety and Immunogenicity of a Recombinant Influenza Vaccine: A Randomized Trial.

Dunkle LM, Izikson R, Patriarca PA, Goldenthal KL, Cox M, Treanor JJ.

Pediatrics. 2018 May;141(5). pii: e20173021. doi: 10.1542/peds.2017-3021. Epub 2018 Apr 2.

18.

A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody.

Nogales A, Piepenbrink MS, Wang J, Ortega S, Basu M, Fucile CF, Treanor JJ, Rosenberg AF, Zand MS, Keefer MC, Martinez-Sobrido L, Kobie JJ.

Sci Rep. 2018 Mar 12;8(1):4374. doi: 10.1038/s41598-018-22307-8.

19.

Influence of Birth Cohort on Effectiveness of 2015-2016 Influenza Vaccine Against Medically Attended Illness Due to 2009 Pandemic Influenza A(H1N1) Virus in the United States.

Flannery B, Smith C, Garten RJ, Levine MZ, Chung JR, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, McLean HQ, Gaglani M, Murthy K, Zimmerman R, Nowalk MP, Griffin MR, Keipp Talbot H, Treanor JJ, Wentworth DE, Fry AM.

J Infect Dis. 2018 Jun 20;218(2):189-196. doi: 10.1093/infdis/jix634.

20.

Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans.

Stadlbauer D, Rajabhathor A, Amanat F, Kaplan D, Masud A, Treanor JJ, Izikson R, Cox MM, Nachbagauer R, Krammer F.

mSphere. 2017 Dec 13;2(6). pii: e00502-17. doi: 10.1128/mSphere.00502-17. eCollection 2017 Nov-Dec.

21.

Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains.

Zost SJ, Parkhouse K, Gumina ME, Kim K, Diaz Perez S, Wilson PC, Treanor JJ, Sant AJ, Cobey S, Hensley SE.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12578-12583. doi: 10.1073/pnas.1712377114. Epub 2017 Nov 6.

22.

Evaluation of the innate immune responses to influenza and live-attenuated influenza vaccine infection in primary differentiated human nasal epithelial cells.

Forero A, Fenstermacher K, Wohlgemuth N, Nishida A, Carter V, Smith EA, Peng X, Hayes M, Francis D, Treanor J, Morrison J, Klein SL, Lane A, Katze MG, Pekosz A.

Vaccine. 2017 Oct 27;35(45):6112-6121. doi: 10.1016/j.vaccine.2017.09.058. Epub 2017 Sep 28.

23.

Maximum Likelihood Estimation of Titer via a Power Family of Four-Parameter Logistic Model.

Yang H, Holden-Wiltse J, Topham DJ, Treanor J.

J Biopharm Stat. 2018;28(3):492-500. doi: 10.1080/10543406.2017.1333996. Epub 2017 Sep 5.

24.

Immunogenicity and safety of a quadrivalent inactivated influenza vaccine compared with two trivalent inactivated influenza vaccines containing alternate B strains in adults: A phase 3, randomized noninferiority study.

Treanor JT, Albano FR, Sawlwin DC, Graves Jones A, Airey J, Formica N, Matassa V, Leong J.

Vaccine. 2017 Apr 4;35(15):1856-1864. doi: 10.1016/j.vaccine.2017.02.066. Epub 2017 Mar 13.

25.

B-Cell Responses to Intramuscular Administration of a Bivalent Virus-Like Particle Human Norovirus Vaccine.

Ramani S, Neill FH, Ferreira J, Treanor JJ, Frey SE, Topham DJ, Goodwin RR, Borkowski A, Baehner F, Mendelman PM, Estes MK, Atmar RL.

Clin Vaccine Immunol. 2017 May 5;24(5). pii: e00571-16. doi: 10.1128/CVI.00571-16. Print 2017 May.

26.

Flu Vaccine-Too Much of a Good Thing?

Treanor J.

J Infect Dis. 2017 Apr 1;215(7):1017-1019. doi: 10.1093/infdis/jix075. No abstract available.

27.

Stable emulsion (SE) alone is an effective adjuvant for a recombinant, baculovirus-expressed H5 influenza vaccine in healthy adults: A Phase 2 trial.

Treanor JJ, Chu L, Essink B, Muse D, El Sahly HM, Izikson R, Goldenthal KL, Patriarca P, Dunkle LM.

Vaccine. 2017 Feb 7;35(6):923-928. doi: 10.1016/j.vaccine.2016.12.053. Epub 2017 Jan 11.

PMID:
28089141
28.

CLINICAL PRACTICE. Influenza Vaccination.

Treanor JJ.

N Engl J Med. 2016 Sep 29;375(13):1261-8. doi: 10.1056/NEJMcp1512870. Review. No abstract available.

PMID:
27682035
29.

Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical Studies.

Hu E, Chen N, Kunz RK, Hwang DR, Michelsen K, Davis C, Ma J, Shi J, Lester-Zeiner D, Hungate R, Treanor J, Chen H, Allen JR.

ACS Med Chem Lett. 2016 May 19;7(7):719-23. doi: 10.1021/acsmedchemlett.6b00185. eCollection 2016 Jul 14.

30.

Correlates of Immunity to Influenza as Determined by Challenge of Children with Live, Attenuated Influenza Vaccine.

Wright PF, Hoen AG, Ilyushina NA, Brown EP, Ackerman ME, Wieland-Alter W, Connor RI, Jegaskanda S, Rosenberg-Hasson Y, Haynes BC, Luke CJ, Subbarao K, Treanor JJ.

Open Forum Infect Dis. 2016 May 23;3(2):ofw108. doi: 10.1093/ofid/ofw108. eCollection 2016 Apr.

31.

Generation and Protective Ability of Influenza Virus-Specific Antibody-Dependent Cellular Cytotoxicity in Humans Elicited by Vaccination, Natural Infection, and Experimental Challenge.

Jegaskanda S, Luke C, Hickman HD, Sangster MY, Wieland-Alter WF, McBride JM, Yewdell JW, Wright PF, Treanor J, Rosenberger CM, Subbarao K.

J Infect Dis. 2016 Sep 15;214(6):945-52. doi: 10.1093/infdis/jiw262. Epub 2016 Jun 28.

32.

Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection.

Henry Dunand CJ, Leon PE, Huang M, Choi A, Chromikova V, Ho IY, Tan GS, Cruz J, Hirsh A, Zheng NY, Mullarkey CE, Ennis FA, Terajima M, Treanor JJ, Topham DJ, Subbarao K, Palese P, Krammer F, Wilson PC.

Cell Host Microbe. 2016 Jun 8;19(6):800-13. doi: 10.1016/j.chom.2016.05.014.

33.

Maternal immunisation with trivalent inactivated influenza vaccine for prevention of influenza in infants in Mali: a prospective, active-controlled, observer-blind, randomised phase 4 trial.

Tapia MD, Sow SO, Tamboura B, Tégueté I, Pasetti MF, Kodio M, Onwuchekwa U, Tennant SM, Blackwelder WC, Coulibaly F, Traoré A, Keita AM, Haidara FC, Diallo F, Doumbia M, Sanogo D, DeMatt E, Schluterman NH, Buchwald A, Kotloff KL, Chen WH, Orenstein EW, Orenstein LAV, Villanueva J, Bresee J, Treanor J, Levine MM.

Lancet Infect Dis. 2016 Sep;16(9):1026-1035. doi: 10.1016/S1473-3099(16)30054-8. Epub 2016 May 31.

34.

Genomics reveals historic and contemporary transmission dynamics of a bacterial disease among wildlife and livestock.

Kamath PL, Foster JT, Drees KP, Luikart G, Quance C, Anderson NJ, Clarke PR, Cole EK, Drew ML, Edwards WH, Rhyan JC, Treanor JJ, Wallen RL, White PJ, Robbe-Austerman S, Cross PC.

Nat Commun. 2016 May 11;7:11448. doi: 10.1038/ncomms11448.

35.

Incidence and viral aetiologies of acute respiratory illnesses (ARIs) in the United States: a population-based study.

Szilagyi PG, Blumkin A, Treanor JJ, Gallivan S, Albertin C, Lofthus GK, Schnabel KC, Donahue JG, Thompson MG, Shay DK.

Epidemiol Infect. 2016 Jul;144(10):2077-86. doi: 10.1017/S0950268816000315. Epub 2016 Mar 2.

PMID:
26931351
36.

Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine-mediated immune protection.

DeDiego ML, Anderson CS, Yang H, Holden-Wiltse J, Fitzgerald T, Treanor JJ, Topham DJ.

Immunology. 2016 Jun;148(2):160-73. doi: 10.1111/imm.12594. Epub 2016 Mar 30.

37.

Seasonal Effectiveness of Live Attenuated and Inactivated Influenza Vaccine.

Chung JR, Flannery B, Thompson MG, Gaglani M, Jackson ML, Monto AS, Nowalk MP, Talbot HK, Treanor JJ, Belongia EA, Murthy K, Jackson LA, Petrie JG, Zimmerman RK, Griffin MR, McLean HQ, Fry AM.

Pediatrics. 2016 Feb;137(2):e20153279. doi: 10.1542/peds.2015-3279. Epub 2016 Jan 5.

38.

Evaluation of the Safety and Immunogenicity of a Candidate Pandemic Live Attenuated Influenza Vaccine (pLAIV) Against Influenza A(H7N9).

Sobhanie M, Matsuoka Y, Jegaskanda S, Fitzgerald T, Mallory R, Chen Z, Luke C, Treanor J, Subbarao K.

J Infect Dis. 2016 Mar 15;213(6):922-9. doi: 10.1093/infdis/jiv526. Epub 2015 Dec 9.

39.

Prospects for Broadly Protective Influenza Vaccines.

Treanor JJ.

Am J Prev Med. 2015 Dec;49(6 Suppl 4):S355-63. doi: 10.1016/j.amepre.2015.09.012. Review.

PMID:
26590435
40.

Editorial Commentary: Is Prepandemic Vaccination a Wise Investment?

Treanor J.

Clin Infect Dis. 2016 Feb 15;62(4):499-500. doi: 10.1093/cid/civ961. Epub 2015 Nov 18. No abstract available.

PMID:
26585521
41.

Maintenance of brucellosis in Yellowstone bison: linking seasonal food resources, host-pathogen interaction, and life-history trade-offs.

Treanor JJ, Geremia C, Ballou MA, Keisler DH, White PJ, Cox JJ, Crowley PH.

Ecol Evol. 2015 Sep;5(17):3783-99. doi: 10.1002/ece3.1633. Epub 2015 Aug 20.

42.

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in adults 18-49 years of age, naive to 23-valent pneumococcal polysaccharide vaccine.

Bryant KA, Frenck R, Gurtman A, Rubino J, Treanor J, Thompson A, Jones TR, Sundaraiyer V, Baxter LM, Gruber WC, Emini EA, Scott DA, Schmoele-Thoma B.

Vaccine. 2015 Oct 26;33(43):5854-5860. doi: 10.1016/j.vaccine.2015.08.080. Epub 2015 Sep 9.

PMID:
26362099
43.

Prospects for broadly protective influenza vaccines.

Treanor JJ.

Vaccine. 2015 Nov 27;33 Suppl 4:D39-45. doi: 10.1016/j.vaccine.2015.08.053. Epub 2015 Sep 1. Review.

PMID:
26338145
44.

Abundance and specificity of influenza reactive circulating memory follicular helper and non-follicular helper CD4 T cells in healthy adults.

Leddon SA, Richards KA, Treanor JJ, Sant AJ.

Immunology. 2015 Sep;146(1):157-62. doi: 10.1111/imm.12491. Epub 2015 Jul 14.

45.

A selective prostaglandin E2 receptor subtype 2 (EP2) antagonist increases the macrophage-mediated clearance of amyloid-beta plaques.

Fox BM, Beck HP, Roveto PM, Kayser F, Cheng Q, Dou H, Williamson T, Treanor J, Liu H, Jin L, Xu G, Ma J, Wang S, Olson SH.

J Med Chem. 2015 Jul 9;58(13):5256-73. doi: 10.1021/acs.jmedchem.5b00567. Epub 2015 Jun 24.

PMID:
26061158
46.

Serological Correlates of Protection against a GII.4 Norovirus.

Atmar RL, Bernstein DI, Lyon GM, Treanor JJ, Al-Ibrahim MS, Graham DY, Vinjé J, Jiang X, Gregoricus N, Frenck RW, Moe CL, Chen WH, Ferreira J, Barrett J, Opekun AR, Estes MK, Borkowski A, Baehner F, Goodwin R, Edmonds A, Mendelman PM.

Clin Vaccine Immunol. 2015 Aug;22(8):923-9. doi: 10.1128/CVI.00196-15. Epub 2015 Jun 3.

47.

Radiosynthesis and initial characterization of a PDE10A specific PET tracer [18F]AMG 580 in non-human primates.

Hwang DR, Hu E, Allen JR, Davis C, Treanor J, Miller S, Chen H, Shi B, Narayanan TK, Barret O, Alagille D, Yu Z, Slifstein M.

Nucl Med Biol. 2015 Aug;42(8):654-63. doi: 10.1016/j.nucmedbio.2015.04.004. Epub 2015 Apr 16.

PMID:
25935386
48.

A Single Dose of an Avian H3N8 Influenza Virus Vaccine Is Highly Immunogenic and Efficacious against a Recently Emerged Seal Influenza Virus in Mice and Ferrets.

Baz M, Paskel M, Matsuoka Y, Zengel JR, Cheng X, Treanor JJ, Jin H, Subbarao K.

J Virol. 2015 Jul;89(13):6907-17. doi: 10.1128/JVI.00280-15. Epub 2015 Apr 22.

49.

Comparison of serum hemagglutinin and neuraminidase inhibition antibodies after 2010-2011 trivalent inactivated influenza vaccination in healthcare personnel.

Laguio-Vila MR, Thompson MG, Reynolds S, Spencer SM, Gaglani M, Naleway A, Ball S, Bozeman S, Baker S, Martínez-Sobrido L, Levine M, Katz J, Fry AM, Treanor JJ.

Open Forum Infect Dis. 2015 Jan 3;2(1):ofu115. doi: 10.1093/ofid/ofu115. eCollection 2015 Jan.

50.

High-Affinity H7 Head and Stalk Domain-Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine.

Halliley JL, Khurana S, Krammer F, Fitzgerald T, Coyle EM, Chung KY, Baker SF, Yang H, Martínez-Sobrido L, Treanor JJ, Subbarao K, Golding H, Topham DJ, Sangster MY.

J Infect Dis. 2015 Oct 15;212(8):1270-8. doi: 10.1093/infdis/jiv210. Epub 2015 Apr 2.

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