Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 29

1.

Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides.

Dickson EJ, Jensen JB, Vivas O, Kruse M, Traynor-Kaplan AE, Hille B.

J Cell Biol. 2016 Apr 11;213(1):33-48. doi: 10.1083/jcb.201508106. Epub 2016 Apr 4.

2.

Control of TMEM16A by INO-4995 and other inositolphosphates.

Tian Y, Schreiber R, Wanitchakool P, Kongsuphol P, Sousa M, Uliyakina I, Palma M, Faria D, Traynor-Kaplan AE, Fragata JI, Amaral MD, Kunzelmann K.

Br J Pharmacol. 2013 Jan;168(1):253-65. doi: 10.1111/j.1476-5381.2012.02193.x.

3.

INO-4995 therapeutic efficacy is enhanced with repeat dosing in cystic fibrosis knockout mice and human epithelia.

Traynor-Kaplan AE, Moody M, Nur M, Gabriel S, Majerus PW, Drumm ML, Langton-Webster B.

Am J Respir Cell Mol Biol. 2010 Jan;42(1):105-12. doi: 10.1165/rcmb.2008-0380OC. Epub 2009 Apr 3.

4.

Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia.

Moody M, Pennington C, Schultz C, Caldwell R, Dinkel C, Rossi MW, McNamara S, Widdicombe J, Gabriel S, Traynor-Kaplan AE.

Am J Physiol Cell Physiol. 2005 Sep;289(3):C512-20. Epub 2005 Apr 27.

5.

Antagonists of myo-inositol 3,4,5,6-tetrakisphosphate allow repeated epithelial chloride secretion.

Rudolf MT, Dinkel C, Traynor-Kaplan AE, Schultz C.

Bioorg Med Chem. 2003 Jul 31;11(15):3315-29.

PMID:
12837542
6.
7.

A membrane-permeant, bioactivatable derivative of Ins(1,3,4)P3 and its effect on Cl(-)-secretion from T84 cells.

Rudolf MT, Traynor-Kaplan AE, Schultz C.

Bioorg Med Chem Lett. 1998 Jul 21;8(14):1857-60.

PMID:
9873447
8.

2-Deoxy derivative is a partial agonist of the intracellular messenger inositol 3,4,5,6-tetrakisphosphate in the epithelial cell line T84.

Rudolf MT, Li WH, Wolfson N, Traynor-Kaplan AE, Schultz C.

J Med Chem. 1998 Sep 10;41(19):3635-44.

PMID:
9733488
10.

D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways.

Eckmann L, Rudolf MT, Ptasznik A, Schultz C, Jiang T, Wolfson N, Tsien R, Fierer J, Shears SB, Kagnoff MF, Traynor-Kaplan AE.

Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14456-60.

11.

Dual role for AlF4(-)-sensitive G proteins in the function of T84 epithelial cells: transport and barrier effects.

Ries J, Stein J, Traynor-Kaplan AE, Barrett KE.

Am J Physiol. 1997 Mar;272(3 Pt 1):C794-803.

PMID:
9124513
12.

Phosphatidylinositol 3-kinase mediates the inhibitory effect of epidermal growth factor on calcium-dependent chloride secretion.

Uribe JM, Keely SJ, Traynor-Kaplan AE, Barrett KE.

J Biol Chem. 1996 Oct 25;271(43):26588-95.

13.

A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophils.

Ptasznik A, Prossnitz ER, Yoshikawa D, Smrcka A, Traynor-Kaplan AE, Bokoch GM.

J Biol Chem. 1996 Oct 11;271(41):25204-7.

14.

Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells.

Uribe JM, Gelbmann CM, Traynor-Kaplan AE, Barrett KE.

Am J Physiol. 1996 Sep;271(3 Pt 1):C914-22.

PMID:
8843722
15.

Rac GTPase interacts specifically with phosphatidylinositol 3-kinase.

Bokoch GM, Vlahos CJ, Wang Y, Knaus UG, Traynor-Kaplan AE.

Biochem J. 1996 May 1;315 ( Pt 3):775-9.

16.
17.

Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase.

Vlahos CJ, Matter WF, Brown RF, Traynor-Kaplan AE, Heyworth PG, Prossnitz ER, Ye RD, Marder P, Schelm JA, Rothfuss KJ, et al.

J Immunol. 1995 Mar 1;154(5):2413-22.

PMID:
7868907
18.

Protein kinase C activity does not mediate the inhibitory effect of carbachol on chloride secretion by T84 cells.

Traynor-Kaplan AE, Buranawuti T, Vajanaphanich M, Barrett KE.

Am J Physiol. 1994 Nov;267(5 Pt 1):C1224-30.

PMID:
7977685
19.

Neutrophil dysfunction in end-stage renal failure: reduced response to priming by C5a.

Dobos GJ, Traynor-Kaplan AE, Ward D, Schollmeyer PJ.

Clin Investig. 1994 May;72(5):353-7.

PMID:
8086769
20.

Actin polymerization, calcium-transients, and phospholipid metabolism in human neutrophils after stimulation with interleukin-8 and N-formyl peptide.

Norgauer J, Krutmann J, Dobos GJ, Traynor-Kaplan AE, Oades ZG, Schraufst├Ątter IU.

J Invest Dermatol. 1994 Mar;102(3):310-4.

21.

Activation by calcium alone of chloride secretion in T84 epithelial cells.

Kachintorn U, Vajanaphanich M, Traynor-Kaplan AE, Dharmsathaphorn K, Barrett KE.

Br J Pharmacol. 1993 Jun;109(2):510-7.

22.

AMP and microamps: neutrophil-derived chloride secretagogue identified.

Traynor-Kaplan AE, Barrett KE.

J Clin Invest. 1993 May;91(5):1857-8. No abstract available.

23.

Elevation of inositol tetrakisphosphate parallels inhibition of Ca(2+)-dependent Cl- secretion in T84 cells.

Kachintorn U, Vajanaphanich M, Barrett KE, Traynor-Kaplan AE.

Am J Physiol. 1993 Mar;264(3 Pt 1):C671-6.

PMID:
8460671
25.
26.

Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?

Eberle M, Traynor-Kaplan AE, Sklar LA, Norgauer J.

J Biol Chem. 1990 Oct 5;265(28):16725-8.

27.

An HPLC procedure for separating polyphosphoinositides on hydroxylapatite.

Boyle LE, Sklar LA, Traynor-Kaplan AE.

J Lipid Res. 1990 Jan;31(1):157-9.

28.

Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils.

Traynor-Kaplan AE, Thompson BL, Harris AL, Taylor P, Omann GM, Sklar LA.

J Biol Chem. 1989 Sep 15;264(26):15668-73.

29.

An inositol tetrakisphosphate-containing phospholipid in activated neutrophils.

Traynor-Kaplan AE, Harris AL, Thompson BL, Taylor P, Sklar LA.

Nature. 1988 Jul 28;334(6180):353-6.

PMID:
3393226

Supplemental Content

Loading ...
Support Center