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Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form.

Altreuter DH, Kirtane AR, Grant T, Kruger C, Traverso G, Bellinger AM.

Expert Opin Drug Deliv. 2018 Nov 5:1-10. doi: 10.1080/17425247.2018.1544615. [Epub ahead of print]


Scalable Gastric Resident Systems for Veterinary Application.

Hayward A, Bensel T, Mazdiyasni H, Rogner J, Kirtane AR, Lee YL, Hua T, Bajpayee A, Collins J, McDonnell S, Cleveland C, Lopes A, Wahane A, Langer R, Traverso G.

Sci Rep. 2018 Aug 7;8(1):11816. doi: 10.1038/s41598-018-30212-3.


Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.


An ingestible bacterial-electronic system to monitor gastrointestinal health.

Mimee M, Nadeau P, Hayward A, Carim S, Flanagan S, Jerger L, Collins J, McDonnell S, Swartwout R, Citorik RJ, Bulović V, Langer R, Traverso G, Chandrakasan AP, Lu TK.

Science. 2018 May 25;360(6391):915-918. doi: 10.1126/science.aas9315.


Caffeine-catalyzed gels.

DiCiccio AM, Lee YL, Glettig DL, Walton ESE, de la Serna EL, Montgomery VA, Grant TM, Langer R, Traverso G.

Biomaterials. 2018 Jul;170:127-135. doi: 10.1016/j.biomaterials.2018.04.010. Epub 2018 Apr 6.


Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams.

Traverso G, Kirtane AR, Schoellhammer CM, Langer R.

Angew Chem Int Ed Engl. 2018 Apr 9;57(16):4156-4163. doi: 10.1002/anie.201712512. Epub 2018 Mar 9. Review.


Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy.

Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, Wu SJ, Grant T, Bellinger AM, Nikolic B, Hayward A, Wood L, Eckhoff PA, Nowak MA, Langer R, Traverso G.

Nat Commun. 2018 Jan 9;9(1):2. doi: 10.1038/s41467-017-02294-6.


Defining optimal permeant characteristics for ultrasound-mediated gastrointestinal delivery.

Schoellhammer CM, Chen Y, Cleveland C, Minahan D, Bensel T, Park JY, Saxton S, Lee YL, Booth L, Langer R, Traverso G.

J Control Release. 2017 Dec 28;268:113-119. doi: 10.1016/j.jconrel.2017.10.023. Epub 2017 Oct 16.


Oral delivery of biologics using drug-device combinations.

Caffarel-Salvador E, Abramson A, Langer R, Traverso G.

Curr Opin Pharmacol. 2017 Oct;36:8-13. doi: 10.1016/j.coph.2017.07.003. Epub 2017 Aug 2. Review.


Triggerable tough hydrogels for gastric resident dosage forms.

Liu J, Pang Y, Zhang S, Cleveland C, Yin X, Booth L, Lin J, Lucy Lee YA, Mazdiyasni H, Saxton S, Kirtane AR, Erlach TV, Rogner J, Langer R, Traverso G.

Nat Commun. 2017 Jul 25;8(1):124. doi: 10.1038/s41467-017-00144-z.


Prolonged energy harvesting for ingestible devices.

Nadeau P, El-Damak D, Glettig D, Kong YL, Mo S, Cleveland C, Booth L, Roxhed N, Langer R, Chandrakasan AP, Traverso G.

Nat Biomed Eng. 2017;1. pii: 0022. doi: 10.1038/s41551-016-0022. Epub 2017 Feb 6.


Wireless Power Transfer to Millimeter-Sized Gastrointestinal Electronics Validated in a Swine Model.

Abid A, O'Brien JM, Bensel T, Cleveland C, Booth L, Smith BR, Langer R, Traverso G.

Sci Rep. 2017 Apr 27;7:46745. doi: 10.1038/srep46745.


Revolutionary reform in psychiatric care in Italy: The abolition of forensic mental hospitals.

Traverso S, Traverso GB.

Crim Behav Ment Health. 2017 Apr;27(2):107-111. doi: 10.1002/cbm.2030. No abstract available.


Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice.

Schoellhammer CM, Lauwers GY, Goettel JA, Oberli MA, Cleveland C, Park JY, Minahan D, Chen Y, Anderson DG, Jaklenec A, Snapper SB, Langer R, Traverso G.

Gastroenterology. 2017 Apr;152(5):1151-1160. doi: 10.1053/j.gastro.2017.01.002. Epub 2017 Jan 11.


Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals.

Bellinger AM, Jafari M, Grant TM, Zhang S, Slater HC, Wenger EA, Mo S, Lee YL, Mazdiyasni H, Kogan L, Barman R, Cleveland C, Booth L, Bensel T, Minahan D, Hurowitz HM, Tai T, Daily J, Nikolic B, Wood L, Eckhoff PA, Langer R, Traverso G.

Sci Transl Med. 2016 Nov 16;8(365):365ra157.


Past, Present, and Future Drug Delivery Systems for Antiretrovirals.

Kirtane AR, Langer R, Traverso G.

J Pharm Sci. 2016 Dec;105(12):3471-3482. doi: 10.1016/j.xphs.2016.09.015. Epub 2016 Oct 19. Review.


Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter.

Lee HC, Ahsen OO, Liang K, Wang Z, Cleveland C, Booth L, Potsaid B, Jayaraman V, Cable AE, Mashimo H, Langer R, Traverso G, Fujimoto JG.

Biomed Opt Express. 2016 Jul 5;7(8):2927-42. doi: 10.1364/BOE.7.002927. eCollection 2016 Aug 1.


Of microneedles and ultrasound: Physical modes of gastrointestinal macromolecule delivery.

Schoellhammer CM, Langer R, Traverso G.

Tissue Barriers. 2016 Feb 11;4(2):e1150235. doi: 10.1080/21688370.2016.1150235. eCollection 2016 Apr-Jun. Review. No abstract available.


A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.

Lee YA, Zhang S, Lin J, Langer R, Traverso G.

Adv Healthc Mater. 2016 May;5(10):1141-6. doi: 10.1002/adhm.201501036. Epub 2016 Apr 6.


Low-frequency ultrasound for drug delivery in the gastrointestinal tract.

Schoellhammer CM, Traverso G.

Expert Opin Drug Deliv. 2016 Aug;13(8):1045-8. doi: 10.1517/17425247.2016.1171841. Epub 2016 Apr 8. No abstract available.


Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.

Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, Harris CC, Papadopoulos N.

Gastroenterology. 2016 Apr;150(4):931-43. doi: 10.1053/j.gastro.2015.12.036. Epub 2016 Jan 5.


Physiologic Status Monitoring via the Gastrointestinal Tract.

Traverso G, Ciccarelli G, Schwartz S, Hughes T, Boettcher T, Barman R, Langer R, Swiston A.

PLoS One. 2015 Nov 18;10(11):e0141666. doi: 10.1371/journal.pone.0141666. eCollection 2015.


Ultrasound-mediated gastrointestinal drug delivery.

Schoellhammer CM, Schroeder A, Maa R, Lauwers GY, Swiston A, Zervas M, Barman R, DiCiccio AM, Brugge WR, Anderson DG, Blankschtein D, Langer R, Traverso G.

Sci Transl Med. 2015 Oct 21;7(310):310ra168. doi: 10.1126/scitranslmed.aaa5937.


An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease.

Zhang S, Ermann J, Succi MD, Zhou A, Hamilton MJ, Cao B, Korzenik JR, Glickman JN, Vemula PK, Glimcher LH, Traverso G, Langer R, Karp JM.

Sci Transl Med. 2015 Aug 12;7(300):300ra128. doi: 10.1126/scitranslmed.aaa5657.


A pH-responsive supramolecular polymer gel as an enteric elastomer for use in gastric devices.

Zhang S, Bellinger AM, Glettig DL, Barman R, Lee YA, Zhu J, Cleveland C, Montgomery VA, Gu L, Nash LD, Maitland DJ, Langer R, Traverso G.

Nat Mater. 2015 Oct;14(10):1065-71. doi: 10.1038/nmat4355. Epub 2015 Jul 27.


Engineering precision.

Traverso G, Langer R.

Sci Transl Med. 2015 May 27;7(289):289ed6. doi: 10.1126/scitranslmed.aab1943. No abstract available.


Ultrahigh speed en face OCT capsule for endoscopic imaging.

Liang K, Traverso G, Lee HC, Ahsen OO, Wang Z, Potsaid B, Giacomelli M, Jayaraman V, Barman R, Cable A, Mashimo H, Langer R, Fujimoto JG.

Biomed Opt Express. 2015 Mar 5;6(4):1146-63. doi: 10.1364/BOE.6.001146. eCollection 2015 Apr 1.


Perspective: Special delivery for the gut.

Traverso G, Langer R.

Nature. 2015 Mar 26;519(7544):S19. doi: 10.1038/519S19a. No abstract available.


Simple battery armor to protect against gastrointestinal injury from accidental ingestion.

Laulicht B, Traverso G, Deshpande V, Langer R, Karp JM.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16490-5. doi: 10.1073/pnas.1418423111. Epub 2014 Nov 3.


Microneedles for drug delivery via the gastrointestinal tract.

Traverso G, Schoellhammer CM, Schroeder A, Maa R, Lauwers GY, Polat BE, Anderson DG, Blankschtein D, Langer R.

J Pharm Sci. 2015 Feb;104(2):362-7. doi: 10.1002/jps.24182. Epub 2014 Sep 22.


Treatment of low bone density in young people with cystic fibrosis: a multicentre, prospective, open-label observational study of calcium and calcifediol followed by a randomised placebo-controlled trial of alendronate.

Bianchi ML, Colombo C, Assael BM, Dubini A, Lombardo M, Quattrucci S, Bella S, Collura M, Messore B, Raia V, Poli F, Bini R, Albanese CV, De Rose V, Costantini D, Romano G, Pustorino E, Magazzù G, Bertasi S, Lucidi V, Traverso G, Coruzzo A, Grzejdziak AD.

Lancet Respir Med. 2013 Jul;1(5):377-85. doi: 10.1016/S2213-2600(13)70064-X. Epub 2013 Jun 2.


Photometric stereo endoscopy.

Parot V, Lim D, González G, Traverso G, Nishioka NS, Vakoc BJ, Durr NJ.

J Biomed Opt. 2013 Jul;18(7):076017. doi: 10.1117/1.JBO.18.7.076017.


Residency training and international medical graduates: coming to America no more.

Traverso G, McMahon GT.

JAMA. 2012 Dec 5;308(21):2193-4. doi: 10.1001/jama.2012.14681. No abstract available.


Stunting is an independent predictor of mortality in patients with cystic fibrosis.

Vieni G, Faraci S, Collura M, Lombardo M, Traverso G, Cristadoro S, Termini L, Lucanto MC, Furnari ML, Trimarchi G, Triglia MR, Costa S, Pellegrino S, Magazzù G.

Clin Nutr. 2013 Jun;32(3):382-5. doi: 10.1016/j.clnu.2012.08.017. Epub 2012 Aug 31.


Nebulized hypertonic saline containing hyaluronic acid improves tolerability in patients with cystic fibrosis and lung disease compared with nebulized hypertonic saline alone: a prospective, randomized, double-blind, controlled study.

Furnari ML, Termini L, Traverso G, Barrale S, Bonaccorso MR, Damiani G, Piparo CL, Collura M.

Ther Adv Respir Dis. 2012 Dec;6(6):315-22. doi: 10.1177/1753465812458984. Epub 2012 Sep 11.


Pediatric liver transplantation: preliminary results at Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione.

Cintorino D, Spada M, Clarizia S, Vasta F, Mandalà L, Aricò M, Traverso G, Luca A, Panarello G, Minervini M, Gruttadauria S, Verzaro R, Volpes R, Scotti Foglieni C, Gridelli B.

Transplant Proc. 2005 Jul-Aug;37(6):2597-8.


Three classes of genes mutated in colorectal cancers with chromosomal instability.

Wang Z, Cummins JM, Shen D, Cahill DP, Jallepalli PV, Wang TL, Parsons DW, Traverso G, Awad M, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz SD, Goldberg ML, Karess R, Kinzler KW, Vogelstein B, Velculescu VE, Lengauer C.

Cancer Res. 2004 May 1;64(9):2998-3001.


Hyper-recombination and genetic instability in BLM-deficient epithelial cells.

Traverso G, Bettegowda C, Kraus J, Speicher MR, Kinzler KW, Vogelstein B, Lengauer C.

Cancer Res. 2003 Dec 15;63(24):8578-81.


High-throughput in vitro translation.

Diehl F, Traverso G.

Discov Med. 2003 Oct;3(18):44-5.


Multicolor in vitro translation.

Traverso G, Diehl F, Hurst R, Shuber A, Whitney D, Johnson C, Levin B, Kinzler KW, Vogelstein B.

Nat Biotechnol. 2003 Sep;21(9):1093-7. Epub 2003 Aug 10.


Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.

Dressman D, Yan H, Traverso G, Kinzler KW, Vogelstein B.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8817-22. Epub 2003 Jul 11.


Detection of proximal colorectal cancers through analysis of faecal DNA.

Traverso G, Shuber A, Olsson L, Levin B, Johnson C, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B.

Lancet. 2002 Feb 2;359(9304):403-4.


Detection of APC mutations in fecal DNA from patients with colorectal tumors.

Traverso G, Shuber A, Levin B, Johnson C, Olsson L, Schoetz DJ Jr, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B.

N Engl J Med. 2002 Jan 31;346(5):311-20.


Detecting colorectal cancer in stool with the use of multiple genetic targets.

Dong SM, Traverso G, Johnson C, Geng L, Favis R, Boynton K, Hibi K, Goodman SN, D'Allessio M, Paty P, Hamilton SR, Sidransky D, Barany F, Levin B, Shuber A, Kinzler KW, Vogelstein B, Jen J.

J Natl Cancer Inst. 2001 Jun 6;93(11):858-65.


Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

Howe JR, Bair JL, Sayed MG, Anderson ME, Mitros FA, Petersen GM, Velculescu VE, Traverso G, Vogelstein B.

Nat Genet. 2001 Jun;28(2):184-7.


Top-down morphogenesis of colorectal tumors.

Shih IM, Wang TL, Traverso G, Romans K, Hamilton SR, Ben-Sasson S, Kinzler KW, Vogelstein B.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2640-5. Epub 2001 Feb 20.


The treatment of the criminally insane in Italy. An overview.

Traverso GB, Ciappi S, Ferracuti S.

Int J Law Psychiatry. 2000 Sep-Dec;23(5-6):493-508. Review. No abstract available.


Genes expressed in human tumor endothelium.

St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW.

Science. 2000 Aug 18;289(5482):1197-202.


Posttransplant human herpes virus 8 infection and seroconversion in a Kaposi's sarcoma affected kidney recipient transplanted from a human herpes virus 8 positive living related donor.

Nocera A, Corbellino M, Valente U, Barocci S, Torre F, De Palma R, Sementa A, Traverso GB, Icardi A, Fontana I, Arcuri V, Poli F, Cagetti P, Moore P, Parravicini C.

Transplant Proc. 1998 Aug;30(5):2095-6. No abstract available.


[Pseudohyperaldosteronism secondary to licorice poisoning associated with hemorrhagic gastritis].

Cataldo F, Di Stefano P, Violante M, Traverso G, Mulè M.

Pediatr Med Chir. 1997 May-Jun;19(3):219-21. Review. Italian.


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