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Items: 8

1.

Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia.

Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM.

Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29.

2.

Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.

Wijeyewickrema LC, Lameignere E, Hor L, Duncan RC, Shiba T, Travers RJ, Kapopara PR, Lei V, Smith SA, Kim H, Morrissey JH, Pike RN, Conway EM.

Blood. 2016 Sep 29;128(13):1766-76. doi: 10.1182/blood-2016-02-699561. Epub 2016 Jun 23.

3.

FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow.

Zhu S, Travers RJ, Morrissey JH, Diamond SL.

Blood. 2015 Sep 17;126(12):1494-502. doi: 10.1182/blood-2015-04-641472. Epub 2015 Jul 1.

4.

How it all starts: Initiation of the clotting cascade.

Smith SA, Travers RJ, Morrissey JH.

Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28. Review.

5.

Polyphosphate, platelets, and coagulation.

Travers RJ, Smith SA, Morrissey JH.

Int J Lab Hematol. 2015 May;37 Suppl 1:31-5. doi: 10.1111/ijlh.12349. Review.

6.

Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.

Shenoi RA, Kalathottukaren MT, Travers RJ, Lai BF, Creagh AL, Lange D, Yu K, Weinhart M, Chew BH, Du C, Brooks DE, Carter CJ, Morrissey JH, Haynes CA, Kizhakkedathu JN.

Sci Transl Med. 2014 Oct 29;6(260):260ra150. doi: 10.1126/scitranslmed.3009427. Epub 2014 Oct 29.

7.

Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis.

Travers RJ, Shenoi RA, Kalathottukaren MT, Kizhakkedathu JN, Morrissey JH.

Blood. 2014 Nov 20;124(22):3183-90. doi: 10.1182/blood-2014-05-577932. Epub 2014 Sep 8.

8.

Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation.

Smith SA, Choi SH, Collins JN, Travers RJ, Cooley BC, Morrissey JH.

Blood. 2012 Dec 20;120(26):5103-10. doi: 10.1182/blood-2012-07-444935. Epub 2012 Sep 11.

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