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Items: 1 to 50 of 304

1.

A phase 1b dose-escalation and expansion study of the BCL-2 inhibitor venetoclax combined with tamoxifen in ER and BCL-2-positive metastatic breast cancer.

Lindeman GJ, Lok SW, Whittle JR, Vaillant F, Teh CE, Lo LL, Policheni AN, Bergin ART, Desai J, Ftouni S, Gandolfo LC, Liew D, Liu HK, Mann GB, Moodie K, Murugasu A, Pal B, Roberts AW, Rosenthal MA, Shackleton K, Silva MJ, Siow ZR, Smyth GK, Taylor L, Travers A, Yeo B, Yeung MM, Zivanovic Bujak A, Dawson SJ, Gray DHD, Visvader JE.

Cancer Discov. 2018 Dec 5. pii: CD-18-1151. doi: 10.1158/2159-8290.CD-18-1151. [Epub ahead of print]

PMID:
30518523
2.
3.

Highly disordered histone H1-DNA model complexes and their condensates.

Turner AL, Watson M, Wilkins OG, Cato L, Travers A, Thomas JO, Stott K.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11964-11969. doi: 10.1073/pnas.1805943115. Epub 2018 Oct 9.

PMID:
30301810
4.

State of the Evidence for Emergency Medical Services (EMS) Care: The Evolution and Current Methodology of the Prehospital Evidence-Based Practice (PEP) Program.

Carter AJE, Jensen JL, Petrie DA, Greene J, Travers A, Goldstein JP, Cook J, Fidgen D, Swain J, Richardson L, Cain E.

Healthc Policy. 2018 Aug;14(1):57-70. doi: 10.12927/hcpol.2018.25548.

5.

Evolution of a high-performance emergency health services system in Nova Scotia.

Travers AH.

Healthc Manage Forum. 2018 Sep;31(5):191-195. doi: 10.1177/0840470418773416. Epub 2018 Aug 2.

PMID:
30071755
6.

Youth Responses to School Shootings: a Review.

Travers Á, McDonagh T, Elklit A.

Curr Psychiatry Rep. 2018 May 19;20(6):47. doi: 10.1007/s11920-018-0903-1. Review.

PMID:
29779059
7.

ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement.

Kleinman ME, Perkins GD, Bhanji F, Billi JE, Bray JE, Callaway CW, de Caen A, Finn JC, Hazinski MF, Lim SH, Maconochie I, Morley P, Nadkarni V, Neumar RW, Nikolaou N, Nolan JP, Reis A, Sierra AF, Singletary EM, Soar J, Stanton D, Travers A, Welsford M, Zideman D.

Resuscitation. 2018 Jun;127:132-146. doi: 10.1016/j.resuscitation.2018.03.021. Epub 2018 Apr 26.

PMID:
29706236
8.

ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement.

Kleinman ME, Perkins GD, Bhanji F, Billi JE, Bray JE, Callaway CW, de Caen A, Finn JC, Hazinski MF, Lim SH, Maconochie I, Nadkarni V, Neumar RW, Nikolaou N, Nolan JP, Reis A, Sierra AF, Singletary EM, Soar J, Stanton D, Travers A, Welsford M, Zideman D.

Circulation. 2018 May 29;137(22):e802-e819. doi: 10.1161/CIR.0000000000000561. Epub 2018 Apr 26. Review. Erratum in: Circulation. 2018 Jul 31;138(5):e77.

PMID:
29700123
9.

Training the next generation of psychotraumatologists: COllaborative Network for Training and EXcellence in psychoTraumatology (CONTEXT).

Vallières F, Hyland P, Murphy J, Hansen M, Shevlin M, Elklit A, Ceannt R, Armour C, Wiedemann N, Munk M, Dinesen C, O'Hare G, Cunningham T, Askerod D, Spitz P, Blackwell N, McCarthy A, O'Dowd L, Scott S, Reid T, Mokake A, Halpin R, Perera C, Gleeson C, Frost R, Flanagan N, Aldamman K, Tamrakar T, Louison Vang M, Sherwood L, Travers Á, Haahr-Pedersen I, Walshe C, McDonagh T, Bramsen RH.

Eur J Psychotraumatol. 2018 Jan 16;9(1):1421001. doi: 10.1080/20008198.2017.1421001. eCollection 2018.

10.

2017 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Summary.

Olasveengen TM, de Caen AR, Mancini ME, Maconochie IK, Aickin R, Atkins DL, Berg RA, Bingham RM, Brooks SC, Castrén M, Chung SP, Considine J, Couto TB, Escalante R, Gazmuri RJ, Guerguerian AM, Hatanaka T, Koster RW, Kudenchuk PJ, Lang E, Lim SH, Løfgren B, Meaney PA, Montgomery WH, Morley PT, Morrison LJ, Nation KJ, Ng KC, Nadkarni VM, Nishiyama C, Nuthall G, Ong GY, Perkins GD, Reis AG, Ristagno G, Sakamoto T, Sayre MR, Schexnayder SM, Sierra AF, Singletary EM, Shimizu N, Smyth MA, Stanton D, Tijssen JA, Travers A, Vaillancourt C, Van de Voorde P, Hazinski MF, Nolan JP; ILCOR Collaborators.

Resuscitation. 2017 Dec;121:201-214. doi: 10.1016/j.resuscitation.2017.10.021. Epub 2017 Nov 8. Review.

PMID:
29128145
11.

2017 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Summary.

Olasveengen TM, de Caen AR, Mancini ME, Maconochie IK, Aickin R, Atkins DL, Berg RA, Bingham RM, Brooks SC, Castrén M, Chung SP, Considine J, Couto TB, Escalante R, Gazmuri RJ, Guerguerian AM, Hatanaka T, Koster RW, Kudenchuk PJ, Lang E, Lim SH, Løfgren B, Meaney PA, Montgomery WH, Morley PT, Morrison LJ, Nation KJ, Ng KC, Nadkarni VM, Nishiyama C, Nuthall G, Ong GY, Perkins GD, Reis AG, Ristagno G, Sakamoto T, Sayre MR, Schexnayder SM, Sierra AF, Singletary EM, Shimizu N, Smyth MA, Stanton D, Tijssen JA, Travers A, Vaillancourt C, Van de Voorde P, Hazinski MF, Nolan JP; ILCOR Collaborators.

Circulation. 2017 Dec 5;136(23):e424-e440. doi: 10.1161/CIR.0000000000000541. Epub 2017 Nov 6. Review. Erratum in: Circulation. 2017 Dec 19;136(25):e468.

PMID:
29114010
12.

2017 American Heart Association Focused Update on Adult Basic Life Support and Cardiopulmonary Resuscitation Quality: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Kleinman ME, Goldberger ZD, Rea T, Swor RA, Bobrow BJ, Brennan EE, Terry M, Hemphill R, Gazmuri RJ, Hazinski MF, Travers AH.

Circulation. 2018 Jan 2;137(1):e7-e13. doi: 10.1161/CIR.0000000000000539. Epub 2017 Nov 6. Review. Erratum in: Circulation. 2018 Jan 2;137(1):e14.

PMID:
29114008
13.

The regulatory role of DNA supercoiling in nucleoprotein complex assembly and genetic activity.

Muskhelishvili G, Travers A.

Biophys Rev. 2016 Nov;8(Suppl 1):5-22. doi: 10.1007/s12551-016-0237-3. Epub 2016 Nov 19. Review.

14.

What are the barriers to initiating end-of-life conversations with patients in the last year of life?

Travers A, Taylor V.

Int J Palliat Nurs. 2016 Sep 2;22(9):454-462. Review.

PMID:
27666307
15.

Contemporary evidence-based practice in Canadian emergency medical services: a vision for integrating evidence into clinical and policy decision-making.

Jensen JL, Travers AH.

CJEM. 2017 May;19(3):220-229. doi: 10.1017/cem.2016.364. Epub 2016 Sep 23. Review.

PMID:
27658352
16.

High-resolution biophysical analysis of the dynamics of nucleosome formation.

Hatakeyama A, Hartmann B, Travers A, Nogues C, Buckle M.

Sci Rep. 2016 Jun 6;6:27337. doi: 10.1038/srep27337.

17.

What is new in the 2015 American Heart Association guidelines, what is recycled from 2010, and what is relevant for emergency medicine in Canada.

Morrison LJ, de Caen A, Bhanji F, Bigham BL, Blanchard IE, Brooks SC, Guerguerian AM, Jensen JL, Travers AH, Vaillancourt C, Welsford M, Woolfrey K.

CJEM. 2016 May;18(3):223-9. doi: 10.1017/cem.2016.26. No abstract available.

PMID:
27138217
18.

Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study.

Green RS, Travers AH, Cain E, Campbell SG, Jensen JL, Petrie DA, Erdogan M, Patrick G, Patrick W.

Emerg Med Int. 2016;2016:6717261. doi: 10.1155/2016/6717261. Epub 2016 Mar 9.

19.

A metastable structure for the compact 30-nm chromatin fibre.

Wu C, McGeehan JE, Travers A.

FEBS Lett. 2016 Apr;590(7):935-42. doi: 10.1002/1873-3468.12128. Epub 2016 Mar 30.

20.

A Survey to Determine Decision-Making Styles of Working Paramedics and Student Paramedics.

Jensen JL, Bienkowski A, Travers AH, Calder LA, Walker M, Tavares W, Croskerry P.

CJEM. 2016 May;18(3):213-22. doi: 10.1017/cem.2015.95. Epub 2016 Feb 2.

PMID:
26832320
21.

Glycosylation of a Fasciclin-Like Arabinogalactan-Protein (SOS5) Mediates Root Growth and Seed Mucilage Adherence via a Cell Wall Receptor-Like Kinase (FEI1/FEI2) Pathway in Arabidopsis.

Basu D, Tian L, Debrosse T, Poirier E, Emch K, Herock H, Travers A, Showalter AM.

PLoS One. 2016 Jan 5;11(1):e0145092. doi: 10.1371/journal.pone.0145092. eCollection 2016.

22.

Impact of a Novel Collaborative Long-Term Care -EMS Model: A Before-and-After Cohort Analysis of an Extended Care Paramedic Program.

Jensen JL, Marshall EG, Carter AJ, Boudreau M, Burge F, Travers AH.

Prehosp Emerg Care. 2016;20(1):111-6. doi: 10.3109/10903127.2015.1051678. Epub 2015 Aug 17.

PMID:
26727341
23.

A small multigene hydroxyproline-O-galactosyltransferase family functions in arabinogalactan-protein glycosylation, growth and development in Arabidopsis.

Basu D, Tian L, Wang W, Bobbs S, Herock H, Travers A, Showalter AM.

BMC Plant Biol. 2015 Dec 21;15:295. doi: 10.1186/s12870-015-0670-7.

24.

Part 1: Executive summary: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

Nolan JP, Hazinski MF, Aickin R, Bhanji F, Billi JE, Callaway CW, Castren M, de Caen AR, Ferrer JM, Finn JC, Gent LM, Griffin RE, Iverson S, Lang E, Lim SH, Maconochie IK, Montgomery WH, Morley PT, Nadkarni VM, Neumar RW, Nikolaou NI, Perkins GD, Perlman JM, Singletary EM, Soar J, Travers AH, Welsford M, Wyllie J, Zideman DA.

Resuscitation. 2015 Oct;95:e1-31. doi: 10.1016/j.resuscitation.2015.07.039. Review. No abstract available.

PMID:
26477703
25.

Part 3: Adult basic life support and automated external defibrillation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

Perkins GD, Travers AH, Berg RA, Castren M, Considine J, Escalante R, Gazmuri RJ, Koster RW, Lim SH, Nation KJ, Olasveengen TM, Sakamoto T, Sayre MR, Sierra A, Smyth MA, Stanton D, Vaillancourt C; Basic Life Support Chapter Collaborators.

Resuscitation. 2015 Oct;95:e43-69. doi: 10.1016/j.resuscitation.2015.07.041. Epub 2015 Oct 15. Review. No abstract available.

PMID:
26477428
26.

Part 2: Evidence evaluation and management of conflicts of interest: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

Morley PT, Lang E, Aickin R, Billi JE, Eigel B, Ferrer JM, Finn JC, Gent LM, Griffin RE, Hazinski MF, Maconochie IK, Montgomery WH, Morrison LJ, Nadkarni VM, Nikolaou NI, Nolan JP, Perkins GD, Sayre MR, Travers AH, Wyllie J, Zideman DA.

Resuscitation. 2015 Oct;95:e33-41. doi: 10.1016/j.resuscitation.2015.07.040. Epub 2015 Oct 15. Review. No abstract available.

PMID:
26477427
27.

Part 6: Alternative Techniques and Ancillary Devices for Cardiopulmonary Resuscitation: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Brooks SC, Anderson ML, Bruder E, Daya MR, Gaffney A, Otto CW, Singer AJ, Thiagarajan RR, Travers AH.

Circulation. 2015 Nov 3;132(18 Suppl 2):S436-43. doi: 10.1161/CIR.0000000000000260. Review. No abstract available.

PMID:
26472994
28.

Part 5: Adult Basic Life Support and Cardiopulmonary Resuscitation Quality: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Kleinman ME, Brennan EE, Goldberger ZD, Swor RA, Terry M, Bobrow BJ, Gazmuri RJ, Travers AH, Rea T.

Circulation. 2015 Nov 3;132(18 Suppl 2):S414-35. doi: 10.1161/CIR.0000000000000259. Review. No abstract available.

PMID:
26472993
29.

Part 4: Systems of Care and Continuous Quality Improvement: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Kronick SL, Kurz MC, Lin S, Edelson DP, Berg RA, Billi JE, Cabanas JG, Cone DC, Diercks DB, Foster JJ, Meeks RA, Travers AH, Welsford M.

Circulation. 2015 Nov 3;132(18 Suppl 2):S397-413. doi: 10.1161/CIR.0000000000000258. Review. No abstract available.

PMID:
26472992
30.

Part 1: Executive Summary: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Neumar RW, Shuster M, Callaway CW, Gent LM, Atkins DL, Bhanji F, Brooks SC, de Caen AR, Donnino MW, Ferrer JM, Kleinman ME, Kronick SL, Lavonas EJ, Link MS, Mancini ME, Morrison LJ, O'Connor RE, Samson RA, Schexnayder SM, Singletary EM, Sinz EH, Travers AH, Wyckoff MH, Hazinski MF.

Circulation. 2015 Nov 3;132(18 Suppl 2):S315-67. doi: 10.1161/CIR.0000000000000252. No abstract available.

PMID:
26472989
31.

Part 3: Adult Basic Life Support and Automated External Defibrillation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

Travers AH, Perkins GD, Berg RA, Castren M, Considine J, Escalante R, Gazmuri RJ, Koster RW, Lim SH, Nation KJ, Olasveengen TM, Sakamoto T, Sayre MR, Sierra A, Smyth MA, Stanton D, Vaillancourt C; Basic Life Support Chapter Collaborators.

Circulation. 2015 Oct 20;132(16 Suppl 1):S51-83. doi: 10.1161/CIR.0000000000000272. Review.

PMID:
26472859
32.

Part 2: Evidence Evaluation and Management of Conflicts of Interest: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

Morley PT, Lang E, Aickin R, Billi JE, Eigel B, Ferrer JM, Finn JC, Gent LM, Griffin RE, Hazinski MF, Maconochie IK, Montgomery WH, Morrison LJ, Nadkarni VM, Nikolaou NI, Nolan JP, Perkins GD, Sayre MR, Travers AH, Wyllie J, Zideman DA.

Circulation. 2015 Oct 20;132(16 Suppl 1):S40-50. doi: 10.1161/CIR.0000000000000271.

PMID:
26472858
33.

Part 1: Executive Summary: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

Hazinski MF, Nolan JP, Aickin R, Bhanji F, Billi JE, Callaway CW, Castren M, de Caen AR, Ferrer JM, Finn JC, Gent LM, Griffin RE, Iverson S, Lang E, Lim SH, Maconochie IK, Montgomery WH, Morley PT, Nadkarni VM, Neumar RW, Nikolaou NI, Perkins GD, Perlman JM, Singletary EM, Soar J, Travers AH, Welsford M, Wyllie J, Zideman DA.

Circulation. 2015 Oct 20;132(16 Suppl 1):S2-39. doi: 10.1161/CIR.0000000000000270. No abstract available.

PMID:
26472854
34.

Chromosomal position shift of a regulatory gene alters the bacterial phenotype.

Gerganova V, Berger M, Zaldastanishvili E, Sobetzko P, Lafon C, Mourez M, Travers A, Muskhelishvili G.

Nucleic Acids Res. 2015 Sep 30;43(17):8215-26. doi: 10.1093/nar/gkv709. Epub 2015 Jul 13.

35.

The Canadian National EMS Research Agenda: Impact and Feasibility of Implementation of Previously Generated Recommendations.

Jensen JL, Blanchard IE, Bigham BL, Carter A, Brown R, Socha D, Brown LH, Travers AH, Craig AM, Morrison LJ.

CJEM. 2015 Sep;17(5):484-90. doi: 10.1017/cem.2015.29. Epub 2015 Jun 11.

PMID:
26062819
36.

Alternatives to Traditional EMS Dispatch and Transport: A Scoping Review of Reported Outcomes.

Jensen JL, Carter AJ, Rose J, Visintini S, Bourdon E, Brown R, McVey J, Travers AH.

CJEM. 2015 Sep;17(5):532-50. doi: 10.1017/cem.2014.59. Epub 2015 Mar 18. Review.

PMID:
26014661
37.

Offload zones to mitigate emergency medical services (EMS) offload delay in the emergency department: a process map and hazard analysis.

Carter AJ, Gould JB, Vanberkel P, Jensen JL, Cook J, Carrigan S, Wheatley MR, Travers AH.

CJEM. 2015 Nov;17(6):670-8. doi: 10.1017/cem.2015.15. Epub 2015 May 21.

PMID:
25994045
38.

The Epidemiology of Prehospital Emergency Responses for Older Adults in a Provincial EMS System.

Goldstein J, Jensen JL, Carter AJ, Travers AH, Rockwood K.

CJEM. 2015 Sep;17(5):491-6. doi: 10.1017/cem.2015.20. Epub 2015 May 20.

PMID:
25989943
39.

DNA structure and function.

Travers A, Muskhelishvili G.

FEBS J. 2015 Jun;282(12):2279-95. doi: 10.1111/febs.13307. Epub 2015 Jun 2. Review.

40.

Upstream binding of idling RNA polymerase modulates transcription initiation from a nearby promoter.

Gerganova V, Maurer S, Stoliar L, Japaridze A, Dietler G, Nasser W, Kutateladze T, Travers A, Muskhelishvili G.

J Biol Chem. 2015 Mar 27;290(13):8095-109. doi: 10.1074/jbc.M114.628131. Epub 2015 Feb 2.

42.
43.

Assessment of older adults by emergency medical services: methodology and feasibility of a care partner Comprehensive Geriatric Assessment (CP-CGA).

Goldstein J, Travers A, Hubbard R, Moorhouse P, Andrew MK, Rockwood K.

CJEM. 2014 Sep;16(5):370-7.

PMID:
25227645
44.

Structural insights into the mechanism of negative regulation of single-box high mobility group proteins by the acidic tail domain.

Stott K, Watson M, Bostock MJ, Mortensen SA, Travers A, Grasser KD, Thomas JO.

J Biol Chem. 2014 Oct 24;289(43):29817-26. doi: 10.1074/jbc.M114.591115. Epub 2014 Sep 4.

45.

Structural biology. The 30-nm fiber redux.

Travers A.

Science. 2014 Apr 25;344(6182):370-2. doi: 10.1126/science.1253852. No abstract available.

PMID:
24763580
46.

Order from the order: how a spatiotemporal genetic program is encoded in a 2-D genetic map of the bacterial chromosome.

Muskhelishvili G, Travers A.

J Mol Microbiol Biotechnol. 2014;24(5-6):332-43. doi: 10.1159/000368852. Epub 2015 Feb 17. Review.

PMID:
25732336
47.

Effects of vitamin A on in vitro maturation of pre-pubertal mouse spermatogonial stem cells.

Travers A, Arkoun B, Safsaf A, Milazzo JP, Absyte A, Bironneau A, Perdrix A, Sibert L, Macé B, Cauliez B, Rives N.

PLoS One. 2013 Dec 9;8(12):e82819. doi: 10.1371/journal.pone.0082819. eCollection 2013.

48.

Dynamic DNA underpins chromosome dynamics.

Travers A.

Biophys J. 2013 Nov 19;105(10):2235-7. doi: 10.1016/j.bpj.2013.10.011.

49.

Insights into the implementation and operation of a novel paramedic long-term care program.

Jensen JL, Travers AH, Marshall EG, Cain E, Leadlay S, Carter AJ.

Prehosp Emerg Care. 2014 Jan-Mar;18(1):86-91. doi: 10.3109/10903127.2013.831506. Epub 2013 Oct 11.

PMID:
24116961
50.

The added value of water, sanitation, and hygiene interventions to mass drug administration for reducing the prevalence of trachoma: a systematic review examining.

Travers A, Strasser S, Palmer SL, Stauber C.

J Environ Public Health. 2013;2013:682093. doi: 10.1155/2013/682093. Epub 2013 Aug 7. Review.

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