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Items: 1 to 50 of 235

1.

Experimental Therapy of Paracoccidioidomycosis Using P10-Primed Monocyte-Derived Dendritic Cells Isolated From Infected Mice.

Silva LBR, Taira CL, Dias LS, Souza ACO, Nosanchuk JD, Travassos LR, Taborda CP.

Front Microbiol. 2019 Jul 31;10:1727. doi: 10.3389/fmicb.2019.01727. eCollection 2019.

2.

Antitumor effect of chiral organotelluranes elicited in a murine melanoma model.

Paschoalin T, Martens AA, Omori ÁT, Pereira FV, Juliano L, Travassos LR, Machado-Santelli GM, Cunha RLOR.

Bioorg Med Chem. 2019 Jun 15;27(12):2537-2545. doi: 10.1016/j.bmc.2019.03.032. Epub 2019 Mar 21.

PMID:
30962115
3.

Molecular, Biological and Structural Features of VL CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells.

Girola N, Resende-Lara PT, Figueiredo CR, Massaoka MH, Azevedo RA, Cunha RLOR, Polonelli L, Travassos LR.

Front Oncol. 2019 Jan 25;9:25. doi: 10.3389/fonc.2019.00025. eCollection 2019.

4.

Leucurogin and melanoma therapy.

Almeida MC, Santos IC, Paschoalin T, Travassos LR, Mauch C, Zigrino P, Pesquero JB, Pesquero JL, Higuchi DA.

Toxicon. 2019 Mar 1;159:22-31. doi: 10.1016/j.toxicon.2018.12.005. Epub 2019 Jan 3.

PMID:
30611825
5.

Peptide R18H from BRN2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo and Induces Apoptosis in B16F10-Nex2 Cells.

da Cunha FFM, Mugnol KCU, de Melo FM, Nascimento MVSQ, de Azevedo RA, Santos RTS, Magalhães JA, Miguel DC, Tada DB, Mortara RA, Travassos LR, Arruda DC.

Anticancer Agents Med Chem. 2019;19(3):389-401. doi: 10.2174/1871520618666181109164246.

PMID:
30417795
6.

Paracoccidioides spp. and Histoplasma capsulatum: Current and New Perspectives for Diagnosis and Treatment.

Taborda CP, Buccheri R, Benard G, Duarte-Neto AN, Nosanchuk JD, Travassos LR.

Curr Top Med Chem. 2018;18(15):1333-1348. doi: 10.2174/1568026618666181002112231. Review.

PMID:
30277157
7.

Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma.

Figueiredo CR, Azevedo RA, Mousdell S, Resende-Lara PT, Ireland L, Santos A, Girola N, Cunha RLOR, Schmid MC, Polonelli L, Travassos LR, Mielgo A.

Front Immunol. 2018 May 23;9:1132. doi: 10.3389/fimmu.2018.01132. eCollection 2018.

8.

Fungicidal activity of peptides encoded by immunoglobulin genes.

Polonelli L, Ciociola T, Sperindè M, Giovati L, D'Adda T, Galati S, Travassos LR, Magliani W, Conti S.

Sci Rep. 2017 Sep 7;7(1):10896. doi: 10.1038/s41598-017-11396-6.

9.

Dendritic Cells Primed with Paracoccidioides brasiliensis Peptide P10 Are Therapeutic in Immunosuppressed Mice with Paracoccidioidomycosis.

Silva LBR, Dias LS, Rittner GMG, Muñoz JE, Souza ACO, Nosanchuk JD, Travassos LR, Taborda CP.

Front Microbiol. 2017 Jun 14;8:1057. doi: 10.3389/fmicb.2017.01057. eCollection 2017.

10.

Peptide Vaccine Against Paracoccidioidomycosis.

Taborda CP, Travassos LR.

Methods Mol Biol. 2017;1625:113-128. doi: 10.1007/978-1-4939-7104-6_9.

PMID:
28584987
11.

Inhibition of melanoma metastasis by dual-peptide PLGA NPS.

Arruda DC, de Oliveira TD, Cursino PHF, Maia VSC, Berzaghi R, Travassos LR, Tada DB.

Biopolymers. 2017 Sep;108(5). doi: 10.1002/bip.23029.

PMID:
28547860
12.

Linear Epitopes of Paracoccidioides brasiliensis and Other Fungal Agents of Human Systemic Mycoses As Vaccine Candidates.

Travassos LR, Taborda CP.

Front Immunol. 2017 Mar 10;8:224. doi: 10.3389/fimmu.2017.00224. eCollection 2017. Review.

13.

Erratum: SOCS1 favors the epithelial-mesenchymal transition in melanoma, promotes tumor progression and prevents antitumor immunity by PD-L1 expression.

Berzaghi R, Maia VS, Pereira FV, Melo FM, Guedes MS, Origassa CS, Scutti JB, Matsuo AL, Câmara NO, Rodrigues EG, Travassos LR.

Sci Rep. 2017 Feb 21;7:42827. doi: 10.1038/srep42827. No abstract available.

14.

SOCS1 favors the epithelial-mesenchymal transition in melanoma, promotes tumor progression and prevents antitumor immunity by PD-L1 expression.

Berzaghi R, Maia VS, Pereira FV, Melo FM, Guedes MS, Origassa CS, Scutti JB, Matsuo AL, Câmara NO, Rodrigues EG, Travassos LR.

Sci Rep. 2017 Jan 12;7:40585. doi: 10.1038/srep40585. Erratum in: Sci Rep. 2017 Feb 21;7:42827.

15.

The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor.

Girola N, Matsuo AL, Figueiredo CR, Massaoka MH, Farias CF, Arruda DC, Azevedo RA, Monteiro HP, Resende-Lara PT, Cunha RL, Polonelli L, Travassos LR.

Peptides. 2016 Nov;85:1-15. doi: 10.1016/j.peptides.2016.08.006. Epub 2016 Aug 26.

PMID:
27575453
16.

A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents.

Polonelli L, Ciociola T, Elviri L, Zanello PP, Giovati L, Arruda DC, Muñoz JE, Mortara RA, Morace G, Borghi E, Galati S, Marin O, Casoli C, Pilotti E, Ronzi P, Travassos LR, Magliani W, Conti S.

Sci Rep. 2016 Oct 11;6:35018. doi: 10.1038/srep35018.

17.

AC-1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model.

Rabaça AN, Arruda DC, Figueiredo CR, Massaoka MH, Farias CF, Tada DB, Maia VC, Silva Junior PI, Girola N, Real F, Mortara RA, Polonelli L, Travassos LR.

FEBS Open Bio. 2016 Jul 15;6(9):885-901. doi: 10.1002/2211-5463.12080. eCollection 2016 Sep.

18.

TLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models.

Pereira FV, Melo AC, de Melo FM, Mourão-Sá D, Silva P, Berzaghi R, Herbozo CC, Coelho-Dos-Reis J, Scutti JA, Origassa CS, Pereira RM, Juliano L, Juliano MA, Carmona AK, Câmara NO, Tsuji M, Travassos LR, Rodrigues EG.

Oncoimmunology. 2016 May 5;5(7):e1178420. doi: 10.1080/2162402X.2016.1178420. eCollection 2016 Jul.

19.

Antibodies Against Glycolipids Enhance Antifungal Activity of Macrophages and Reduce Fungal Burden After Infection with Paracoccidioides brasiliensis.

Bueno RA, Thomaz L, Muñoz JE, da Silva CJ, Nosanchuk JD, Pinto MR, Travassos LR, Taborda CP.

Front Microbiol. 2016 Feb 3;7:74. doi: 10.3389/fmicb.2016.00074. eCollection 2016.

20.

Benzofuroxan derivatives N-Br and N-I induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo.

Farias CF, Massaoka MH, Girola N, Azevedo RA, Ferreira AK, Jorge SD, Tavares LC, Figueiredo CR, Travassos LR.

BMC Cancer. 2015 Oct 27;15:807. doi: 10.1186/s12885-015-1835-3.

21.

Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo.

Girola N, Figueiredo CR, Farias CF, Azevedo RA, Ferreira AK, Teixeira SF, Capello TM, Martins EG, Matsuo AL, Travassos LR, Lago JH.

Biochem Biophys Res Commun. 2015 Nov 27;467(4):928-34. doi: 10.1016/j.bbrc.2015.10.041. Epub 2015 Oct 16.

PMID:
26471302
22.

PARACOCCIDIOIDOMYCOSIS: CHALLENGES IN THE DEVELOPMENT OF A VACCINE AGAINST AN ENDEMIC MYCOSIS IN THE AMERICAS.

Taborda CP, Urán ME, Nosanchuk JD, Travassos LR.

Rev Inst Med Trop Sao Paulo. 2015 Sep;57 Suppl 19:21-4. doi: 10.1590/S0036-46652015000700005. Review.

23.

A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo.

Figueiredo CR, Matsuo AL, Azevedo RA, Massaoka MH, Girola N, Polonelli L, Travassos LR.

Sci Rep. 2015 Sep 22;5:14310. doi: 10.1038/srep14310.

24.

Extracellular vesicles from Paracoccidioides pathogenic species transport polysaccharide and expose ligands for DC-SIGN receptors.

Peres da Silva R, Heiss C, Black I, Azadi P, Gerlach JQ, Travassos LR, Joshi L, Kilcoyne M, Puccia R.

Sci Rep. 2015 Sep 21;5:14213. doi: 10.1038/srep14213.

25.

Antitumor activity of kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice.

Figueiredo CR, Matsuo AL, Massaoka MH, Girola N, Azevedo RA, Rabaça AN, Farias CF, Pereira FV, Matias NS, Silva LP, Rodrigues EG, Lago JH, Travassos LR, Silva RM.

Adv Pharm Bull. 2014 Oct;4(Suppl 1):429-36. doi: 10.5681/apb.2014.063. Epub 2014 Aug 25.

26.

Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo.

de Azevedo RA, Figueiredo CR, Ferreira AK, Matsuo AL, Massaoka MH, Girola N, Auada AV, Farias CF, Pasqualoto KF, Rodrigues CP, Barbuto JA, Levy D, Bydlowski SP, de Sá-Junior PL, Travassos LR, Lebrun I.

Peptides. 2015 Jun;68:113-9. doi: 10.1016/j.peptides.2014.09.024. Epub 2014 Oct 14.

PMID:
25305549
27.

Anti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10.

de Melo FM, Braga CJ, Pereira FV, Maricato JT, Origassa CS, Souza MF, Melo AC, Silva P, Tomaz SL, Gimenes KP, Scutti JA, Juliano MA, Zamboni DS, Câmara NO, Travassos LR, Ferreira LC, Rodrigues EG.

Immunol Cell Biol. 2015 Jan;93(1):86-98. doi: 10.1038/icb.2014.74. Epub 2014 Sep 16.

PMID:
25223833
28.

A subtraction tolerization method of immunization allowed for Wilms' tumor protein-1 (WT1) identification in melanoma and discovery of an antitumor peptide sequence.

Massaoka MH, Matsuo AL, Figueiredo CR, Girola N, Farias CF, Pasqualoto K, Travassos LR.

J Immunol Methods. 2014 Dec 1;414:11-9. doi: 10.1016/j.jim.2014.08.003. Epub 2014 Sep 6.

PMID:
25205401
29.

Monoclonal antibodies to heat shock protein 60 induce a protective immune response against experimental Paracoccidioides lutzii.

Thomaz L, Nosanchuk JD, Rossi DC, Travassos LR, Taborda CP.

Microbes Infect. 2014 Sep;16(9):788-95. doi: 10.1016/j.micinf.2014.08.004. Epub 2014 Aug 24.

PMID:
25161111
30.

Immunization with P10 peptide increases specific immunity and protects immunosuppressed BALB/c mice infected with virulent yeasts of Paracoccidioides brasiliensis.

Muñoz JE, Luft VD, Amorim J, Magalhães A, Thomaz L, Nosanchuk JD, Travassos LR, Taborda CP.

Mycopathologia. 2014 Oct;178(3-4):177-88. doi: 10.1007/s11046-014-9801-1. Epub 2014 Aug 19.

PMID:
25135302
31.

Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo.

Figueiredo CR, Matsuo AL, Pereira FV, Rabaça AN, Farias CF, Girola N, Massaoka MH, Azevedo RA, Scutti JA, Arruda DC, Silva LP, Rodrigues EG, Lago JH, Travassos LR, Silva RM.

Pharmacogn Mag. 2014 Apr;10(Suppl 2):S363-76. doi: 10.4103/0973-1296.133284.

32.

Anti-tumor activities of peptides corresponding to conserved complementary determining regions from different immunoglobulins.

Figueiredo CR, Matsuo AL, Massaoka MH, Polonelli L, Travassos LR.

Peptides. 2014 Sep;59:14-9. doi: 10.1016/j.peptides.2014.06.007. Epub 2014 Jun 24.

PMID:
24972300
33.

Radiochemical pharmacokinetic profile of P10 peptide with antifungal properties.

Faintuch BL, Oliveira EA, Munõz JE, Travassos LR, Taborda CP.

Med Mycol. 2014 Jul;52(5):546-51. doi: 10.1093/mmy/myu024. Epub 2014 Jun 15.

PMID:
24934802
34.

A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies.

Pereira FV, Ferreira-Guimarães CA, Paschoalin T, Scutti JA, Melo FM, Silva LS, Melo AC, Silva P, Tiago M, Matsuo AL, Juliano L, Juliano MA, Carmona AK, Travassos LR, Rodrigues EG.

PLoS One. 2014 Apr 30;9(4):e96141. doi: 10.1371/journal.pone.0096141. eCollection 2014.

35.

A novel cell-penetrating peptide derived from WT1 enhances p53 activity, induces cell senescence and displays antimelanoma activity in xeno- and syngeneic systems.

Massaoka MH, Matsuo AL, Figueiredo CR, Girola N, Faria CF, Azevedo RA, Travassos LR.

FEBS Open Bio. 2014 Jan 21;4:153-61. doi: 10.1016/j.fob.2014.01.007. eCollection 2014.

36.

Sialoglycoproteins in morphological distinct stages of Mucor polymorphosporus and their influence on phagocytosis by human blood phagocytes.

Almeida CA, de Campos-Takaki GM, Portela MB, Travassos LR, Alviano CS, Alviano DS.

Mycopathologia. 2013 Oct;176(3-4):183-9. doi: 10.1007/s11046-013-9692-6. Epub 2013 Aug 14.

PMID:
23943428
37.

DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells.

de Amorim J, Magalhães A, Muñoz JE, Rittner GM, Nosanchuk JD, Travassos LR, Taborda CP.

Microbes Infect. 2013 Mar;15(3):181-91. doi: 10.1016/j.micinf.2012.11.007. Epub 2012 Nov 28.

38.

Paracoccidioidomycosis vaccine.

Travassos LR, Taborda CP.

Hum Vaccin Immunother. 2012 Oct;8(10):1450-3. doi: 10.4161/hv.21283. Epub 2012 Aug 16. Review.

39.

Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.

Massaoka MH, Matsuo AL, Figueiredo CR, Farias CF, Girola N, Arruda DC, Scutti JA, Romoff P, Favero OA, Ferreira MJ, Lago JH, Travassos LR.

PLoS One. 2012;7(6):e38698. doi: 10.1371/journal.pone.0038698. Epub 2012 Jun 6.

40.

New advances in the development of a vaccine against paracoccidioidomycosis.

Travassos LR, Taborda CP.

Front Microbiol. 2012 Jun 12;3:212. doi: 10.3389/fmicb.2012.00212. eCollection 2012.

41.

The role of adjuvants in therapeutic protection against paracoccidioidomycosis after immunization with the P10 peptide.

Mayorga O, Muñoz JE, Lincopan N, Teixeira AF, Ferreira LC, Travassos LR, Taborda CP.

Front Microbiol. 2012 May 4;3:154. doi: 10.3389/fmicb.2012.00154. eCollection 2012.

42.

Chitin-like molecules associate with Cryptococcus neoformans glucuronoxylomannan to form a glycan complex with previously unknown properties.

Ramos CL, Fonseca FL, Rodrigues J, Guimarães AJ, Cinelli LP, Miranda K, Nimrichter L, Casadevall A, Travassos LR, Rodrigues ML.

Eukaryot Cell. 2012 Sep;11(9):1086-94. doi: 10.1128/EC.00001-12. Epub 2012 May 4.

43.

Peptides of the constant region of antibodies display fungicidal activity.

Polonelli L, Ciociola T, Magliani W, Zanello PP, D'Adda T, Galati S, De Bernardis F, Arancia S, Gabrielli E, Pericolini E, Vecchiarelli A, Arruda DC, Pinto MR, Travassos LR, Pertinhez TA, Spisni A, Conti S.

PLoS One. 2012;7(3):e34105. doi: 10.1371/journal.pone.0034105. Epub 2012 Mar 21.

44.

Therapeutic DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis.

Rittner GM, Muñoz JE, Marques AF, Nosanchuk JD, Taborda CP, Travassos LR.

PLoS Negl Trop Dis. 2012;6(2):e1519. doi: 10.1371/journal.pntd.0001519. Epub 2012 Feb 28.

45.

β-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma.

Arruda DC, Santos LC, Melo FM, Pereira FV, Figueiredo CR, Matsuo AL, Mortara RA, Juliano MA, Rodrigues EG, Dobroff AS, Polonelli L, Travassos LR.

J Biol Chem. 2012 Apr 27;287(18):14912-22. doi: 10.1074/jbc.M111.322362. Epub 2012 Feb 13.

46.

Prophylactic and therapeutic vaccination using dendritic cells primed with peptide 10 derived from the 43-kilodalton glycoprotein of Paracoccidioides brasiliensis.

Magalhães A, Ferreira KS, Almeida SR, Nosanchuk JD, Travassos LR, Taborda CP.

Clin Vaccine Immunol. 2012 Jan;19(1):23-9. doi: 10.1128/CVI.05414-11. Epub 2011 Nov 16.

47.

C7a, a biphosphinic cyclopalladated compound, efficiently controls the development of a patient-derived xenograft model of adult T cell leukemia/lymphoma.

Guimaraes-Correa AB, Crawford LB, Figueiredo CR, Gimenes KP, Pinto LA, Grassi MF, Feuer G, Travassos LR, Caires AC, Rodrigues EG, Marriott SJ.

Viruses. 2011 Jul;3(7):1041-58. doi: 10.3390/v3071041. Epub 2011 Jul 5.

48.

A new phage-display tumor-homing peptide fused to antiangiogenic peptide generates a novel bioactive molecule with antimelanoma activity.

Matsuo AL, Juliano MA, Figueiredo CR, Batista WL, Tanaka AS, Travassos LR.

Mol Cancer Res. 2011 Nov;9(11):1471-8. doi: 10.1158/1541-7786.MCR-10-0501. Epub 2011 Sep 7.

49.

α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model.

Matsuo AL, Figueiredo CR, Arruda DC, Pereira FV, Scutti JA, Massaoka MH, Travassos LR, Sartorelli P, Lago JH.

Biochem Biophys Res Commun. 2011 Jul 29;411(2):449-54. doi: 10.1016/j.bbrc.2011.06.176. Epub 2011 Jul 2.

50.

A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells.

Serrano FA, Matsuo AL, Monteforte PT, Bechara A, Smaili SS, Santana DP, Rodrigues T, Pereira FV, Silva LS, Machado J Jr, Santos EL, Pesquero JB, Martins RM, Travassos LR, Caires AC, Rodrigues EG.

BMC Cancer. 2011 Jul 14;11:296. doi: 10.1186/1471-2407-11-296.

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