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Items: 1 to 50 of 372

1.

In honor of Professor Samuel J. Danishefsky.

Inoue M, Trauner D.

J Antibiot (Tokyo). 2019 Jun;72(6):324. doi: 10.1038/s41429-019-0182-z. Epub 2019 May 27. No abstract available.

PMID:
31130728
2.

New players in phototherapy: photopharmacology and bio-integrated optoelectronics.

Morstein J, Trauner D.

Curr Opin Chem Biol. 2019 Jun;50:145-151. doi: 10.1016/j.cbpa.2019.03.013. Epub 2019 May 17. Review.

PMID:
31108317
3.

Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy.

O'Donnell-Luria AH, Pais LS, Faundes V, Wood JC, Sveden A, Luria V, Abou Jamra R, Accogli A, Amburgey K, Anderlid BM, Azzarello-Burri S, Basinger AA, Bianchini C, Bird LM, Buchert R, Carre W, Ceulemans S, Charles P, Cox H, Culliton L, Currò A; Deciphering Developmental Disorders (DDD) Study, Demurger F, Dowling JJ, Duban-Bedu B, Dubourg C, Eiset SE, Escobar LF, Ferrarini A, Haack TB, Hashim M, Heide S, Helbig KL, Helbig I, Heredia R, Héron D, Isidor B, Jonasson AR, Joset P, Keren B, Kok F, Kroes HY, Lavillaureix A, Lu X, Maas SM, Maegawa GHB, Marcelis CLM, Mark PR, Masruha MR, McLaughlin HM, McWalter K, Melchinger EU, Mercimek-Andrews S, Nava C, Pendziwiat M, Person R, Ramelli GP, Ramos LLP, Rauch A, Reavey C, Renieri A, Rieß A, Sanchez-Valle A, Sattar S, Saunders C, Schwarz N, Smol T, Srour M, Steindl K, Syrbe S, Taylor JC, Telegrafi A, Thiffault I, Trauner DA, van der Linden H Jr, van Koningsbruggen S, Villard L, Vogel I, Vogt J, Weber YG, Wentzensen IM, Widjaja E, Zak J, Baxter S, Banka S, Rodan LH.

Am J Hum Genet. 2019 Jun 6;104(6):1210-1222. doi: 10.1016/j.ajhg.2019.03.021. Epub 2019 May 9.

PMID:
31079897
4.

Mapping the Azolog Space Enables the Optical Control of New Biological Targets.

Morstein J, Awale M, Reymond JL, Trauner D.

ACS Cent Sci. 2019 Apr 24;5(4):607-618. doi: 10.1021/acscentsci.8b00881. Epub 2019 Mar 13.

5.

Optical control of sphingosine-1-phosphate formation and function.

Morstein J, Hill RZ, Novak AJE, Feng S, Norman DD, Donthamsetti PC, Frank JA, Harayama T, Williams BM, Parrill AL, Tigyi GJ, Riezman H, Isacoff EY, Bautista DM, Trauner D.

Nat Chem Biol. 2019 Jun;15(6):623-631. doi: 10.1038/s41589-019-0269-7. Epub 2019 Apr 29.

PMID:
31036923
6.

Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course.

Castro K, Ntranos A, Amatruda M, Petracca M, Kosa P, Chen EY, Morstein J, Trauner D, Watson CT, Kiebish MA, Bielekova B, Inglese M, Katz Sand I, Casaccia P.

EBioMedicine. 2019 May;43:392-410. doi: 10.1016/j.ebiom.2019.03.087. Epub 2019 Apr 10.

7.

Synthesis and biological evaluation of (±)-hippolachnin and analogs.

Winter N, Rupcic Z, Stadler M, Trauner D.

J Antibiot (Tokyo). 2019 Jun;72(6):375-383. doi: 10.1038/s41429-019-0176-x. Epub 2019 Apr 12.

PMID:
30979942
8.

Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides.

Kol M, Williams B, Toombs-Ruane H, Franquelim HG, Korneev S, Schroeer C, Schwille P, Trauner D, Holthuis JC, Frank JA.

Elife. 2019 Feb 5;8. pii: e43230. doi: 10.7554/eLife.43230.

9.

Hierarchical processing of visual stimuli in nephropathic cystinosis.

Sathappan A, Trauner D.

J Inherit Metab Dis. 2019 May;42(3):545-552. doi: 10.1002/jimd.12062. Epub 2019 Feb 19.

PMID:
30671973
10.

Risk to the supply of ecosystem services across aquatic ecosystems.

Culhane F, Teixeira H, Nogueira AJA, Borgwardt F, Trauner D, Lillebø A, Piet G, Kuemmerlen M, McDonald H, O'Higgins T, Barbosa AL, van der Wal JT, Iglesias-Campos A, Arevalo-Torres J, Barbière J, Robinson LA.

Sci Total Environ. 2019 Apr 10;660:611-621. doi: 10.1016/j.scitotenv.2018.12.346. Epub 2018 Dec 24.

11.

Exploring variability in environmental impact risk from human activities across aquatic ecosystems.

Borgwardt F, Robinson L, Trauner D, Teixeira H, Nogueira AJA, Lillebø AI, Piet G, Kuemmerlen M, O'Higgins T, McDonald H, Arevalo-Torres J, Barbosa AL, Iglesias-Campos A, Hein T, Culhane F.

Sci Total Environ. 2019 Feb 20;652:1396-1408. doi: 10.1016/j.scitotenv.2018.10.339. Epub 2018 Oct 26.

12.

Linking biodiversity to ecosystem services supply: Patterns across aquatic ecosystems.

Teixeira H, Lillebø AI, Culhane F, Robinson L, Trauner D, Borgwardt F, Kuemmerlen M, Barbosa A, McDonald H, Funk A, O'Higgins T, Van der Wal JT, Piet G, Hein T, Arévalo-Torres J, Iglesias-Campos A, Barbière J, Nogueira AJA.

Sci Total Environ. 2019 Mar 20;657:517-534. doi: 10.1016/j.scitotenv.2018.11.440. Epub 2018 Dec 3.

13.

Biomimetic Approach Toward Enterocin and Deoxyenterocin.

Rizzo A, Mayer RJ, Trauner D.

J Org Chem. 2019 Feb 1;84(3):1162-1175. doi: 10.1021/acs.joc.8b02273. Epub 2019 Jan 18.

PMID:
30520624
14.

Identification of conservation and restoration priority areas in the Danube River based on the multi-functionality of river-floodplain systems.

Funk A, Martínez-López J, Borgwardt F, Trauner D, Bagstad KJ, Balbi S, Magrach A, Villa F, Hein T.

Sci Total Environ. 2019 Mar 1;654:763-777. doi: 10.1016/j.scitotenv.2018.10.322. Epub 2018 Oct 30.

15.

Introduction: Optogenetics and Photopharmacology.

Bamberg E, Gärtner W, Trauner D.

Chem Rev. 2018 Nov 14;118(21):10627-10628. doi: 10.1021/acs.chemrev.8b00483. No abstract available.

PMID:
30424609
16.

Optical tools for understanding the complexity of β-cell signalling and insulin release.

Frank JA, Broichhagen J, Yushchenko DA, Trauner D, Schultz C, Hodson DJ.

Nat Rev Endocrinol. 2018 Dec;14(12):721-737. doi: 10.1038/s41574-018-0105-2. Review.

PMID:
30356209
17.

Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles.

Urban P, Pritzl SD, Konrad DB, Frank JA, Pernpeintner C, Roeske CR, Trauner D, Lohmüller T.

Langmuir. 2018 Nov 6;34(44):13368-13374. doi: 10.1021/acs.langmuir.8b03241. Epub 2018 Oct 22.

PMID:
30346771
18.

Biomimetic Synthesis of (+)-Aspergillin PZ.

Reyes JR, Winter N, Spessert L, Trauner D.

Angew Chem Int Ed Engl. 2018 Nov 19;57(47):15587-15591. doi: 10.1002/anie.201809703. Epub 2018 Nov 2.

PMID:
30239081
19.

Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors.

Durand-de Cuttoli R, Mondoloni S, Marti F, Lemoine D, Nguyen C, Naudé J, d'Izarny-Gargas T, Pons S, Maskos U, Trauner D, Kramer RH, Faure P, Mourot A.

Elife. 2018 Sep 4;7. pii: e37487. doi: 10.7554/eLife.37487.

20.

A Versatile Bis-Allylboron Reagent for the Stereoselective Synthesis of Chiral Diols.

Hetzler BE, Volpin G, Vignoni E, Petrovic AG, Proni G, Hu CT, Trauner D.

Angew Chem Int Ed Engl. 2018 Oct 22;57(43):14276-14280. doi: 10.1002/anie.201808234. Epub 2018 Oct 5.

PMID:
30144261
21.

SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand.

Farrants H, Gutzeit VA, Acosta-Ruiz A, Trauner D, Johnsson K, Levitz J, Broichhagen J.

ACS Chem Biol. 2018 Sep 21;13(9):2682-2688. doi: 10.1021/acschembio.8b00628. Epub 2018 Sep 7.

PMID:
30141622
22.

Optical control of L-type Ca2+ channels using a diltiazem photoswitch.

Fehrentz T, Huber FME, Hartrampf N, Bruegmann T, Frank JA, Fine NHF, Malan D, Danzl JG, Tikhonov DB, Sumser M, Sasse P, Hodson DJ, Zhorov BS, Klöcker N, Trauner D.

Nat Chem Biol. 2018 Aug;14(8):764-767. doi: 10.1038/s41589-018-0090-8. Epub 2018 Jul 16.

PMID:
30013061
23.

Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine.

Leippe P, Winter N, Sumser MP, Trauner D.

ACS Chem Neurosci. 2018 Dec 19;9(12):2886-2891. doi: 10.1021/acschemneuro.8b00279. Epub 2018 Aug 14.

PMID:
30001098
24.

In Vivo Photopharmacology.

Hüll K, Morstein J, Trauner D.

Chem Rev. 2018 Nov 14;118(21):10710-10747. doi: 10.1021/acs.chemrev.8b00037. Epub 2018 Jul 9.

PMID:
29985590
25.

Total Synthesis of (±)-Exotine B.

Cheng B, Volpin G, Morstein J, Trauner D.

Org Lett. 2018 Jul 20;20(14):4358-4361. doi: 10.1021/acs.orglett.8b01817. Epub 2018 Jul 6.

26.

Auditory neglect in children following perinatal stroke.

Martin K, Trauner DA.

Behav Brain Res. 2019 Feb 1;359:878-885. doi: 10.1016/j.bbr.2018.06.026. Epub 2018 Jun 25.

PMID:
29953906
27.

Total Synthesis of the Norhasubanan Alkaloid Stephadiamine.

Hartrampf N, Winter N, Pupo G, Stoltz BM, Trauner D.

J Am Chem Soc. 2018 Jul 18;140(28):8675-8680. doi: 10.1021/jacs.8b01918. Epub 2018 Jul 9.

PMID:
29889502
28.

Optical control of GPR40 signalling in pancreatic β-cells.

Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D.

Chem Sci. 2017 Nov 1;8(11):7604-7610. doi: 10.1039/c7sc01475a. Epub 2017 Aug 30.

29.

Toward (-)-Enterocin: An Improved Cuprate Barbier Protocol To Overcome Strain and Sterical Hindrance.

Rizzo A, Trauner D.

Org Lett. 2018 Apr 6;20(7):1841-1844. doi: 10.1021/acs.orglett.8b00353. Epub 2018 Mar 19.

PMID:
29553746
30.

Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.

Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Cao K, Kramer RH, Trauner D, Flannery J, Isacoff EY.

Nat Commun. 2018 Mar 13;9(1):1112. doi: 10.1038/s41467-018-03585-2.

31.

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.

Podewin T, Ast J, Broichhagen J, Fine NHF, Nasteska D, Leippe P, Gailer M, Buenaventura T, Kanda N, Jones BJ, M'Kadmi C, Baneres JL, Marie J, Tomas A, Trauner D, Hoffmann-Röder A, Hodson DJ.

ACS Cent Sci. 2018 Feb 28;4(2):166-179. doi: 10.1021/acscentsci.7b00237. Epub 2018 Jan 16.

32.

A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6.

Häfner S, Burg F, Kannler M, Urban N, Mayer P, Dietrich A, Trauner D, Broichhagen J, Schaefer M.

ChemMedChem. 2018 May 23;13(10):1028-1035. doi: 10.1002/cmdc.201800021. Epub 2018 Apr 26.

PMID:
29522264
33.

Azomethine Ylide Cycloaddition Approach toward Dendrobine: Synthesis of 5-Deoxymubironine C.

Williams BM, Trauner D.

J Org Chem. 2018 Mar 16;83(6):3061-3068. doi: 10.1021/acs.joc.8b00192. Epub 2018 Mar 6.

PMID:
29490142
34.

Selective Synthesis of Divergolide I.

Terwilliger DW, Trauner D.

J Am Chem Soc. 2018 Feb 28;140(8):2748-2751. doi: 10.1021/jacs.7b13092. Epub 2018 Feb 15.

PMID:
29376358
35.

A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity.

DuBay KH, Iwan K, Osorio-Planes L, Geissler PL, Groll M, Trauner D, Broichhagen J.

ACS Chem Biol. 2018 Mar 16;13(3):793-800. doi: 10.1021/acschembio.7b00862. Epub 2018 Feb 9.

PMID:
29357237
36.

Reversible optical control of F1 Fo -ATP synthase using photoswitchable inhibitors.

Eisel B, Hartrampf FWW, Meier T, Trauner D.

FEBS Lett. 2018 Feb;592(3):343-355. doi: 10.1002/1873-3468.12958. Epub 2018 Feb 1.

37.

Comparison of Spontaneously Elicited Language Patterns in Specific Language Impairment and High-Functioning Autism.

Craig M, Trauner D.

Pediatr Neurol. 2018 Feb;79:53-58. doi: 10.1016/j.pediatrneurol.2017.09.017. Epub 2017 Oct 5.

38.

The Chemist and the Architect.

Trauner D.

Angew Chem Int Ed Engl. 2018 Apr 9;57(16):4177-4191. doi: 10.1002/anie.201708325. Epub 2017 Dec 27. Review.

PMID:
29281154
39.

PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels.

Leinders-Zufall T, Storch U, Bleymehl K, Mederos Y Schnitzler M, Frank JA, Konrad DB, Trauner D, Gudermann T, Zufall F.

Cell Chem Biol. 2018 Feb 15;25(2):215-223.e3. doi: 10.1016/j.chembiol.2017.11.008. Epub 2017 Dec 21.

40.

Optical Control of a Biological Reaction-Diffusion System.

Glock P, Broichhagen J, Kretschmer S, Blumhardt P, Mücksch J, Trauner D, Schwille P.

Angew Chem Int Ed Engl. 2018 Feb 23;57(9):2362-2366. doi: 10.1002/anie.201712002. Epub 2018 Jan 26.

PMID:
29266672
41.

Associations Between Social Functioning, ADHD Symptomatology, and Emotion Functioning in Children With Autism Spectrum Disorder and Williams Syndrome.

Ng R, Bellugi U, Trauner D.

Pediatr Neurol. 2018 Feb;79:69-71. doi: 10.1016/j.pediatrneurol.2017.10.022. Epub 2017 Nov 6. No abstract available.

PMID:
29229231
42.

Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor.

Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Cao K, Kramer RH, Trauner D, Flannery J, Isacoff EY.

Nat Commun. 2017 Nov 30;8(1):1862. doi: 10.1038/s41467-017-01990-7. Erratum in: Nat Commun. 2018 Mar 13;9(1):1112.

43.

Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist.

Donthamsetti PC, Winter N, Schönberger M, Levitz J, Stanley C, Javitch JA, Isacoff EY, Trauner D.

J Am Chem Soc. 2017 Dec 27;139(51):18522-18535. doi: 10.1021/jacs.7b07659. Epub 2017 Dec 13.

44.

Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.

Westphal MV, Schafroth MA, Sarott RC, Imhof MA, Bold CP, Leippe P, Dhopeshwarkar A, Grandner JM, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA.

J Am Chem Soc. 2017 Dec 20;139(50):18206-18212. doi: 10.1021/jacs.7b06456. Epub 2017 Dec 12.

PMID:
29161035
45.

Neuroanatomical correlates of emotion-processing in children with unilateral brain lesion: A preliminary study of limbic system organization.

Ng R, Lai P, Brown TT, Järvinen A, Halgren E, Bellugi U, Trauner D.

Soc Neurosci. 2018 Dec;13(6):688-700. doi: 10.1080/17470919.2017.1386126. Epub 2017 Oct 9.

PMID:
28990866
46.

Specificity and Speed: Tethered Photopharmacology.

Leippe P, Koehler Leman J, Trauner D.

Biochemistry. 2017 Oct 3;56(39):5214-5220. doi: 10.1021/acs.biochem.7b00687. Epub 2017 Sep 14. Review.

PMID:
28876905
47.

Total Synthesis of Crocagin A.

Bihelovic F, Stichnoth D, Surup F, Müller R, Trauner D.

Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12848-12851. doi: 10.1002/anie.201612641. Epub 2017 Sep 18.

PMID:
28812331
48.

Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (±)-Hippolachnin A.

Winter N, Trauner D.

J Am Chem Soc. 2017 Aug 30;139(34):11706-11709. doi: 10.1021/jacs.7b06815. Epub 2017 Aug 16.

PMID:
28753024
49.

Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops "Dragon's Blood".

Schmid M, Trauner D.

Angew Chem Int Ed Engl. 2017 Sep 25;56(40):12332-12335. doi: 10.1002/anie.201705390. Epub 2017 Aug 16.

PMID:
28736831
50.

Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2.

Cheng B, Müller R, Trauner D.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12755-12759. doi: 10.1002/anie.201705387. Epub 2017 Aug 30.

PMID:
28731542

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