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Items: 1 to 50 of 52

1.

Molecular physiology of chemical defenses in a poison frog.

Caty SN, Alvarez-Buylla A, Byrd GD, Vidoudez C, Roland AB, Tapia EE, Budnik B, Trauger SA, Coloma LA, O'Connell LA.

J Exp Biol. 2019 Jun 20;222(Pt 12). pii: jeb204149. doi: 10.1242/jeb.204149.

PMID:
31138640
2.

Hydrogen peroxide as a hydride donor and reductant under biologically relevant conditions.

Htet Y, Lu Z, Trauger SA, Tennyson AG.

Chem Sci. 2018 Dec 14;10(7):2025-2033. doi: 10.1039/c8sc05418e. eCollection 2019 Feb 21.

3.

Seasonal changes in diet and chemical defense in the Climbing Mantella frog (Mantella laevigata).

Moskowitz NA, Roland AB, Fischer EK, Ranaivorazo N, Vidoudez C, Aguilar MT, Caldera SM, Chea J, Cristus MG, Crowdis JP, DeMessie B, desJardins-Park CR, Effenberger AH, Flores F, Giles M, He EY, Izmaylov NS, Lee CC, Pagel NA, Phu KK, Rosen LU, Seda DA, Shen Y, Vargas S, Murray AW, Abebe E, Trauger SA, Donoso DA, Vences M, O'Connell LA.

PLoS One. 2018 Dec 26;13(12):e0207940. doi: 10.1371/journal.pone.0207940. eCollection 2018. Erratum in: PLoS One. 2019 Jun 20;14(6):e0218981.

4.

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation.

Serebryany E, Yu S, Trauger SA, Budnik B, Shakhnovich EI.

J Biol Chem. 2018 Nov 16;293(46):17997-18009. doi: 10.1074/jbc.RA118.004551. Epub 2018 Sep 21.

5.

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW, Katz M, Fleming J, Maitra A, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D, Wargo JA, Golub TR, Straussman R.

Science. 2017 Sep 15;357(6356):1156-1160. doi: 10.1126/science.aah5043.

6.

Planarian regeneration in space: Persistent anatomical, behavioral, and bacteriological changes induced by space travel.

Morokuma J, Durant F, Williams KB, Finkelstein JM, Blackiston DJ, Clements T, Reed DW, Roberts M, Jain M, Kimel K, Trauger SA, Wolfe BE, Levin M.

Regeneration (Oxf). 2017 Jun 13;4(2):85-102. doi: 10.1002/reg2.79. eCollection 2017 Apr.

7.

Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity.

Bhattacharyya S, Bershtein S, Yan J, Argun T, Gilson AI, Trauger SA, Shakhnovich EI.

Elife. 2016 Dec 10;5. pii: e20309. doi: 10.7554/eLife.20309.

8.

ChREBP regulates fructose-induced glucose production independently of insulin signaling.

Kim MS, Krawczyk SA, Doridot L, Fowler AJ, Wang JX, Trauger SA, Noh HL, Kang HJ, Meissen JK, Blatnik M, Kim JK, Lai M, Herman MA.

J Clin Invest. 2016 Nov 1;126(11):4372-4386. doi: 10.1172/JCI81993. Epub 2016 Sep 26.

9.

Identification of Residues in the Lipopolysaccharide ABC Transporter That Coordinate ATPase Activity with Extractor Function.

Simpson BW, Owens TW, Orabella MJ, Davis RM, May JM, Trauger SA, Kahne D, Ruiz N.

MBio. 2016 Oct 18;7(5). pii: e01729-16. doi: 10.1128/mBio.01729-16.

10.

How the glycosyltransferase OGT catalyzes amide bond cleavage.

Janetzko J, Trauger SA, Lazarus MB, Walker S.

Nat Chem Biol. 2016 Nov;12(11):899-901. doi: 10.1038/nchembio.2173. Epub 2016 Sep 12.

11.

Response to Heethoff, Norton, and Raspotnig: Ant and Mite Diversity Drives Toxin Variation in the Little Devil Poison Frog and Erratum.

McGugan JR, Byrd GD, Roland AB, Caty SN, Kabir N, Tapia EE, Trauger SA, Coloma LA, O'Connell LA.

J Chem Ecol. 2016 Aug;42(8):845-848.

PMID:
27672058
12.

Erratum to: Ant and Mite Diversity Drives Toxin Variation in the Little Devil Poison Frog.

McGugan JR, Byrd GD, Roland AB, Caty SN, Kabir N, Tapia EE, Trauger SA, Coloma LA, O'Connell LA.

J Chem Ecol. 2016 Aug;42(8):849. No abstract available.

PMID:
27600809
13.

The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine.

Chidley C, Trauger SA, Birsoy K, O'Shea EK.

Elife. 2016 Jul 12;5. pii: e14601. doi: 10.7554/eLife.14601.

14.

Ant and Mite Diversity Drives Toxin Variation in the Little Devil Poison Frog.

McGugan JR, Byrd GD, Roland AB, Caty SN, Kabir N, Tapia EE, Trauger SA, Coloma LA, O'Connell LA.

J Chem Ecol. 2016 Jun;42(6):537-51. doi: 10.1007/s10886-016-0715-x. Epub 2016 Jun 18. Erratum in: J Chem Ecol. 2016 Aug;42(8):849.

PMID:
27318689
15.

The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis.

Hofmann NA, Yang J, Trauger SA, Nakayama H, Huang L, Strunk D, Moses MA, Klagsbrun M, Bischoff J, Graier WF.

Br J Pharmacol. 2015 Aug;172(16):4107-18. doi: 10.1111/bph.13196. Epub 2015 Jun 26.

16.

Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.

Cypess AM, Weiner LS, Roberts-Toler C, Franquet Elía E, Kessler SH, Kahn PA, English J, Chatman K, Trauger SA, Doria A, Kolodny GM.

Cell Metab. 2015 Jan 6;21(1):33-8. doi: 10.1016/j.cmet.2014.12.009.

17.

Data-driven synthesis of proteolysis-resistant peptide hormones.

Prothiwa M, Syed I, Huising MO, van der Meulen T, Donaldson CJ, Trauger SA, Kahn BB, Saghatelian A.

J Am Chem Soc. 2014 Dec 24;136(51):17710-3. doi: 10.1021/ja5065735. Epub 2014 Dec 12.

PMID:
25496053
18.

Nanostructure imaging mass spectrometry: the role of fluorocarbons in metabolite analysis and yoctomole level sensitivity.

Kurczy ME, Northen TR, Trauger SA, Siuzdak G.

Methods Mol Biol. 2015;1203:141-9. doi: 10.1007/978-1-4939-1357-2_14. Review.

19.

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.

Mayo L, Trauger SA, Blain M, Nadeau M, Patel B, Alvarez JI, Mascanfroni ID, Yeste A, Kivisäkk P, Kallas K, Ellezam B, Bakshi R, Prat A, Antel JP, Weiner HL, Quintana FJ.

Nat Med. 2014 Oct;20(10):1147-56. doi: 10.1038/nm.3681. Epub 2014 Sep 14.

20.

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.

Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J.

Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14.

21.

Lysine addressability and mammalian cell interactions of bacteriophage λ procapsids.

Koudelka KJ, Ippoliti S, Medina E, Shriver LP, Trauger SA, Catalano CE, Manchester M.

Biomacromolecules. 2013 Dec 9;14(12):4169-76. doi: 10.1021/bm401577f. Epub 2013 Nov 26.

PMID:
24251756
22.

In vivo performance of a drug-eluting contact lens to treat glaucoma for a month.

Ciolino JB, Stefanescu CF, Ross AE, Salvador-Culla B, Cortez P, Ford EM, Wymbs KA, Sprague SL, Mascoop DR, Rudina SS, Trauger SA, Cade F, Kohane DS.

Biomaterials. 2014 Jan;35(1):432-9. doi: 10.1016/j.biomaterials.2013.09.032. Epub 2013 Oct 4.

23.

Identification of collagen-based materials in cultural heritage.

Kirby DP, Buckley M, Promise E, Trauger SA, Holdcraft TR.

Analyst. 2013 Sep 7;138(17):4849-58. doi: 10.1039/c3an00925d. Epub 2013 Jun 28.

PMID:
23807214
24.

ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC.

Blankman JL, Long JZ, Trauger SA, Siuzdak G, Cravatt BF.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1500-5. doi: 10.1073/pnas.1217121110. Epub 2013 Jan 7.

25.

Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids.

Long JZ, Cisar JS, Milliken D, Niessen S, Wang C, Trauger SA, Siuzdak G, Cravatt BF.

Nat Chem Biol. 2011 Sep 18;7(11):763-5. doi: 10.1038/nchembio.659.

26.

A computational framework for proteome-wide pursuit and prediction of metalloproteins using ICP-MS and MS/MS data.

Lancaster WA, Praissman JL, Poole FL 2nd, Cvetkovic A, Menon AL, Scott JW, Jenney FE Jr, Thorgersen MP, Kalisiak E, Apon JV, Trauger SA, Siuzdak G, Tainer JA, Adams MW.

BMC Bioinformatics. 2011 Feb 28;12:64. doi: 10.1186/1471-2105-12-64.

27.

Type I signal peptidase and protein secretion in Staphylococcus epidermidis.

Powers ME, Smith PA, Roberts TC, Fowler BJ, King CC, Trauger SA, Siuzdak G, Romesberg FE.

J Bacteriol. 2011 Jan;193(2):340-8. doi: 10.1128/JB.01052-10. Epub 2010 Nov 12.

28.

Short communication: quantitative proteomic plasma profiling reveals activation of host defense to oxidative stress in chronic SIV and methamphetamine comorbidity.

Pendyala G, Trauger SA, Siuzdak G, Fox HS.

AIDS Res Hum Retroviruses. 2011 Feb;27(2):179-82. doi: 10.1089/aid.2010.0090. Epub 2010 Oct 7.

29.

The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice.

Kopp F, Komatsu T, Nomura DK, Trauger SA, Thomas JR, Siuzdak G, Simon GM, Cravatt BF.

Chem Biol. 2010 Aug 27;17(8):831-40. doi: 10.1016/j.chembiol.2010.06.009.

30.

Microbial metalloproteomes are largely uncharacterized.

Cvetkovic A, Menon AL, Thorgersen MP, Scott JW, Poole FL 2nd, Jenney FE Jr, Lancaster WA, Praissman JL, Shanmukh S, Vaccaro BJ, Trauger SA, Kalisiak E, Apon JV, Siuzdak G, Yannone SM, Tainer JA, Adams MW.

Nature. 2010 Aug 5;466(7307):779-82. doi: 10.1038/nature09265. Epub 2010 Jul 18.

PMID:
20639861
31.

Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis.

Facciotti MT, Pang WL, Lo FY, Whitehead K, Koide T, Masumura K, Pan M, Kaur A, Larsen DJ, Reiss DJ, Hoang L, Kalisiak E, Northen T, Trauger SA, Siuzdak G, Baliga NS.

BMC Syst Biol. 2010 May 14;4:64. doi: 10.1186/1752-0509-4-64.

32.

Metabolic oxidation regulates embryonic stem cell differentiation.

Yanes O, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G.

Nat Chem Biol. 2010 Jun;6(6):411-7. doi: 10.1038/nchembio.364. Epub 2010 May 2.

33.
34.

Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy.

Dorrell MI, Aguilar E, Jacobson R, Trauger SA, Friedlander J, Siuzdak G, Friedlander M.

Glia. 2010 Jan 1;58(1):43-54. doi: 10.1002/glia.20900.

35.

Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry.

Woo HK, Go EP, Hoang L, Trauger SA, Bowen B, Siuzdak G, Northen TR.

Rapid Commun Mass Spectrom. 2009 Jun;23(12):1849-55. doi: 10.1002/rcm.4076.

36.

Endothelial targeting of cowpea mosaic virus (CPMV) via surface vimentin.

Koudelka KJ, Destito G, Plummer EM, Trauger SA, Siuzdak G, Manchester M.

PLoS Pathog. 2009 May;5(5):e1000417. doi: 10.1371/journal.ppat.1000417. Epub 2009 May 1.

37.

Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys.

Pendyala G, Trauger SA, Kalisiak E, Ellis RJ, Siuzdak G, Fox HS.

J Proteome Res. 2009 May;8(5):2253-60. doi: 10.1021/pr800854t.

38.

Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach.

Kalisiak J, Trauger SA, Kalisiak E, Morita H, Fokin VV, Adams MW, Sharpless KB, Siuzdak G.

J Am Chem Soc. 2009 Jan 14;131(1):378-86. doi: 10.1021/ja808172n.

39.

Novel multiprotein complexes identified in the hyperthermophilic archaeon Pyrococcus furiosus by non-denaturing fractionation of the native proteome.

Menon AL, Poole FL 2nd, Cvetkovic A, Trauger SA, Kalisiak E, Scott JW, Shanmukh S, Praissman J, Jenney FE Jr, Wikoff WR, Apon JV, Siuzdak G, Adams MW.

Mol Cell Proteomics. 2009 Apr;8(4):735-51. doi: 10.1074/mcp.M800246-MCP200. Epub 2008 Nov 28.

40.

Quantitative ESI-TOF analysis of macromolecular assembly kinetics.

Bunner AE, Trauger SA, Siuzdak G, Williamson JR.

Anal Chem. 2008 Dec 15;80(24):9379-86. doi: 10.1021/ac8020505.

41.

Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose.

Hu Y, Suarez J, Fricovsky E, Wang H, Scott BT, Trauger SA, Han W, Hu Y, Oyeleye MO, Dillmann WH.

J Biol Chem. 2009 Jan 2;284(1):547-55. doi: 10.1074/jbc.M808518200. Epub 2008 Nov 12.

42.

XCMS2: processing tandem mass spectrometry data for metabolite identification and structural characterization.

Benton HP, Wong DM, Trauger SA, Siuzdak G.

Anal Chem. 2008 Aug 15;80(16):6382-9. doi: 10.1021/ac800795f. Epub 2008 Jul 16.

43.

Correlating the transcriptome, proteome, and metabolome in the environmental adaptation of a hyperthermophile.

Trauger SA, Kalisak E, Kalisiak J, Morita H, Weinberg MV, Menon AL, Poole FL 2nd, Adams MW, Siuzdak G.

J Proteome Res. 2008 Mar;7(3):1027-35. doi: 10.1021/pr700609j. Epub 2008 Feb 2.

PMID:
18247545
44.

Selective metabolite and peptide capture/mass detection using fluorous affinity tags.

Go EP, Uritboonthai W, Apon JV, Trauger SA, Nordstrom A, O'Maille G, Brittain SM, Peters EC, Siuzdak G.

J Proteome Res. 2007 Apr;6(4):1492-9. Epub 2007 Mar 8.

45.

Mass spectrometry reveals specific and global molecular transformations during viral infection.

Go EP, Wikoff WR, Shen Z, O'Maille G, Morita H, Conrads TP, Nordstrom A, Trauger SA, Uritboonthai W, Lucas DA, Chan KC, Veenstra TD, Lewicki H, Oldstone MB, Schneemann A, Siuzdak G.

J Proteome Res. 2006 Sep;5(9):2405-16.

46.

Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry.

Want EJ, O'Maille G, Smith CA, Brandon TR, Uritboonthai W, Qin C, Trauger SA, Siuzdak G.

Anal Chem. 2006 Feb 1;78(3):743-52.

PMID:
16448047
47.

METLIN: a metabolite mass spectral database.

Smith CA, O'Maille G, Want EJ, Qin C, Trauger SA, Brandon TR, Custodio DE, Abagyan R, Siuzdak G.

Ther Drug Monit. 2005 Dec;27(6):747-51.

PMID:
16404815
48.

Assignment of endogenous substrates to enzymes by global metabolite profiling.

Saghatelian A, Trauger SA, Want EJ, Hawkins EG, Siuzdak G, Cravatt BF.

Biochemistry. 2004 Nov 16;43(45):14332-9.

PMID:
15533037
49.

The identification of an adenovirus receptor by using affinity capture and mass spectrometry.

Trauger SA, Wu E, Bark SJ, Nemerow GR, Siuzdak G.

Chembiochem. 2004 Aug 6;5(8):1095-9.

PMID:
15300833
50.

High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon.

Trauger SA, Go EP, Shen Z, Apon JV, Compton BJ, Bouvier ES, Finn MG, Siuzdak G.

Anal Chem. 2004 Aug 1;76(15):4484-9.

PMID:
15283591

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