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Items: 1 to 50 of 151

1.

Tracking antigen specific T-cells: Technological advancement and limitations.

Dey S, Kamil Reza K, Wuethrich A, Korbie D, Ibn Sina AA, Trau M.

Biotechnol Adv. 2018 Nov 30. pii: S0734-9750(18)30194-0. doi: 10.1016/j.biotechadv.2018.11.010. [Epub ahead of print] Review.

PMID:
30508573
2.

Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker.

Sina AA, Carrascosa LG, Liang Z, Grewal YS, Wardiana A, Shiddiky MJA, Gardiner RA, Samaratunga H, Gandhi MK, Scott RJ, Korbie D, Trau M.

Nat Commun. 2018 Dec 4;9(1):4915. doi: 10.1038/s41467-018-07214-w.

3.

A high-resolution study of in situ surface-enhanced Raman scattering nanotag behavior in biological systems.

Wang J, Anderson W, Li J, Lin LL, Wang Y, Trau M.

J Colloid Interface Sci. 2018 Nov 12;537:536-546. doi: 10.1016/j.jcis.2018.11.035. [Epub ahead of print]

PMID:
30469121
4.

A Sample-to-Targeted Gene Analysis Biochip for Nanofluidic Manipulation of Solid-Phase Circulating Tumor Nucleic Acid Amplification in Liquid Biopsies.

Koo KM, Dey S, Trau M.

ACS Sens. 2018 Nov 21. doi: 10.1021/acssensors.8b01011. [Epub ahead of print]

PMID:
30461262
5.

A SERS microfluidic platform for targeting multiple soluble immune checkpoints.

Reza KK, Sina AA, Wuethrich A, Grewal YS, Howard CB, Korbie D, Trau M.

Biosens Bioelectron. 2018 Oct 25;126:178-186. doi: 10.1016/j.bios.2018.10.044. [Epub ahead of print]

PMID:
30415152
6.

"Mix-to-Go" Silver Colloidal Strategy for Prostate Cancer Molecular Profiling and Risk Prediction.

Wang J, Koo KM, Wang Y, Trau M.

Anal Chem. 2018 Nov 6;90(21):12698-12705. doi: 10.1021/acs.analchem.8b02959. Epub 2018 Oct 12.

PMID:
30260630
7.

Facile One-Pot Synthesis of Nanodot-Decorated Gold-Silver Alloy Nanoboxes for Single-Particle Surface-Enhanced Raman Scattering Activity.

Li J, Zhang G, Wang J, Maksymov IS, Greentree AD, Hu J, Shen A, Wang Y, Trau M.

ACS Appl Mater Interfaces. 2018 Sep 26;10(38):32526-32535. doi: 10.1021/acsami.8b10112. Epub 2018 Sep 17.

PMID:
30168708
8.

Parallel profiling of cancer cells and proteins using a graphene oxide functionalized ac-EHD SERS immunoassay.

Reza KK, Dey S, Wuethrich A, Sina AA, Korbie D, Wang Y, Trau M.

Nanoscale. 2018 Oct 21;10(39):18482-18491. doi: 10.1039/c8nr02886a. Epub 2018 Aug 31.

PMID:
30168562
9.

Multiplexed SERS Detection of Soluble Cancer Protein Biomarkers with Gold-Silver Alloy Nanoboxes and Nanoyeast Single-Chain Variable Fragments.

Li J, Wang J, Grewal YS, Howard CB, Raftery LJ, Mahler S, Wang Y, Trau M.

Anal Chem. 2018 Sep 4;90(17):10377-10384. doi: 10.1021/acs.analchem.8b02216. Epub 2018 Aug 20.

PMID:
30085658
10.

Design and Clinical Verification of Surface-Enhanced Raman Spectroscopy Diagnostic Technology for Individual Cancer Risk Prediction.

Koo KM, Wang J, Richards RS, Farrell A, Yaxley JW, Samaratunga H, Teloken PE, Roberts MJ, Coughlin GD, Lavin MF, Mainwaring PN, Wang Y, Gardiner RA, Trau M.

ACS Nano. 2018 Aug 28;12(8):8362-8371. doi: 10.1021/acsnano.8b03698. Epub 2018 Jul 26.

PMID:
30028592
11.

An exosomal- and interfacial-biosensing based strategy for remote monitoring of aberrantly phosphorylated proteins in lung cancer cells.

Ahmed M, Carrascosa LG, Wuethrich A, Mainwaring P, Trau M.

Biomater Sci. 2018 Aug 21;6(9):2336-2341. doi: 10.1039/c8bm00629f.

PMID:
30022183
12.

Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges.

Lane RE, Korbie D, Hill MM, Trau M.

Clin Transl Med. 2018 May 31;7(1):14. doi: 10.1186/s40169-018-0192-7. Review.

13.

Correction: Nucleic acid purification from plants, animals and microbes in under 30 seconds.

Zou Y, Mason MG, Wang Y, Wee E, Turni C, Blackall PJ, Trau M, Botella JR.

PLoS Biol. 2018 May 7;16(5):e1002630. doi: 10.1371/journal.pbio.1002630. eCollection 2018 May.

14.

Characterising the phenotypic evolution of circulating tumour cells during treatment.

Tsao SC, Wang J, Wang Y, Behren A, Cebon J, Trau M.

Nat Commun. 2018 Apr 16;9(1):1482. doi: 10.1038/s41467-018-03725-8.

15.

Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers.

Wuethrich A, Sina AA, Ahmed M, Lin TY, Carrascosa LG, Trau M.

Nanoscale. 2018 Jun 14;10(23):10884-10890. doi: 10.1039/C7NR09496E.

PMID:
29565425
16.

Amplification-Free Multi-RNA-Type Profiling for Cancer Risk Stratification via Alternating Current Electrohydrodynamic Nanomixing.

Koo KM, Dey S, Trau M.

Small. 2018 Apr;14(17):e1704025. doi: 10.1002/smll.201704025. Epub 2018 Mar 12.

PMID:
29527804
17.

Maskless 3D Ablation of Precise Microhole Structures in Plastics Using Femtosecond Laser Pulses.

Liao C, Anderson W, Antaw F, Trau M.

ACS Appl Mater Interfaces. 2018 Jan 31;10(4):4315-4323. doi: 10.1021/acsami.7b18029. Epub 2018 Jan 17.

PMID:
29313352
18.

Nucleic acid purification from plants, animals and microbes in under 30 seconds.

Zou Y, Mason MG, Wang Y, Wee E, Turni C, Blackall PJ, Trau M, Botella JR.

PLoS Biol. 2017 Nov 21;15(11):e2003916. doi: 10.1371/journal.pbio.2003916. eCollection 2017 Nov. Erratum in: PLoS Biol. 2018 May 7;16(5):e1002630.

19.

Simple and rapid colorimetric detection of melanoma circulating tumor cells using bifunctional magnetic nanoparticles.

Li J, Wang J, Wang Y, Trau M.

Analyst. 2017 Dec 4;142(24):4788-4793. doi: 10.1039/c7an01102d.

PMID:
29139486
20.

A multiplex microplatform for the detection of multiple DNA methylation events using gold-DNA affinity.

Sina AA, Foster MT, Korbie D, Carrascosa LG, Shiddiky MJA, Gao J, Dey S, Trau M.

Analyst. 2017 Oct 7;142(19):3573-3578. doi: 10.1039/c7an00611j. Epub 2017 Sep 1.

PMID:
28861578
21.

Enabling miniaturised personalised diagnostics: from lab-on-a-chip to lab-in-a-drop.

Koo KM, Wee EJH, Wang Y, Trau M.

Lab Chip. 2017 Sep 26;17(19):3200-3220. doi: 10.1039/c7lc00587c. Review.

PMID:
28850136
22.

Purification Protocols for Extracellular Vesicles.

Lane RE, Korbie D, Trau M, Hill MM.

Methods Mol Biol. 2017;1660:111-130. doi: 10.1007/978-1-4939-7253-1_10.

PMID:
28828652
23.

PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome.

O'Leary VB, Smida J, Buske FA, Carrascosa LG, Azimzadeh O, Maugg D, Hain S, Tapio S, Heidenreich W, Kerr J, Trau M, Ovsepian SV, Atkinson MJ.

Sci Rep. 2017 Aug 2;7(1):7163. doi: 10.1038/s41598-017-07295-5.

24.

Isothermal Point Mutation Detection: Toward a First-Pass Screening Strategy for Multidrug-Resistant Tuberculosis.

Ng BYC, Wee EJH, Woods K, Anderson W, Antaw F, Tsang HZH, West NP, Trau M.

Anal Chem. 2017 Sep 5;89(17):9017-9022. doi: 10.1021/acs.analchem.7b01685. Epub 2017 Aug 15.

PMID:
28766343
25.

Evaluation of Different Oligonucleotide Base Substitutions at CpG Binding sites in Multiplex Bisulfite-PCR sequencing.

Lu J, Ru K, Candiloro I, Dobrovic A, Korbie D, Trau M.

Sci Rep. 2017 Mar 22;7:45096. doi: 10.1038/srep45096.

26.

A nanoplasmonic label-free surface-enhanced Raman scattering strategy for non-invasive cancer genetic subtyping in patient samples.

Wang J, Koo KM, Wee EJ, Wang Y, Trau M.

Nanoscale. 2017 Mar 9;9(10):3496-3503. doi: 10.1039/c6nr09928a.

PMID:
28240336
27.

PrimerSuite: A High-Throughput Web-Based Primer Design Program for Multiplex Bisulfite PCR.

Lu J, Johnston A, Berichon P, Ru KL, Korbie D, Trau M.

Sci Rep. 2017 Jan 24;7:41328. doi: 10.1038/srep41328.

28.

Specific and Sensitive Isothermal Electrochemical Biosensor for Plant Pathogen DNA Detection with Colloidal Gold Nanoparticles as Probes.

Lau HY, Wu H, Wee EJ, Trau M, Wang Y, Botella JR.

Sci Rep. 2017 Jan 17;7:38896. doi: 10.1038/srep38896.

29.

Electrohydrodynamic-Induced SERS Immunoassay for Extensive Multiplexed Biomarker Sensing.

Kamil Reza K, Wang J, Vaidyanathan R, Dey S, Wang Y, Trau M.

Small. 2017 Mar;13(9). doi: 10.1002/smll.201602902. Epub 2016 Dec 22.

PMID:
28004880
30.

Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions.

Ahmed M, Carrascosa LG, Ibn Sina AA, Zarate EM, Korbie D, Ru KL, Shiddiky MJA, Mainwaring P, Trau M.

Biosens Bioelectron. 2017 May 15;91:8-14. doi: 10.1016/j.bios.2016.12.012. Epub 2016 Dec 7.

PMID:
27984707
31.

Comprehensive evaluation of molecular enhancers of the isothermal exponential amplification reaction.

Mok E, Wee E, Wang Y, Trau M.

Sci Rep. 2016 Dec 2;6:37837. doi: 10.1038/srep37837.

32.

High-speed biosensing strategy for non-invasive profiling of multiple cancer fusion genes in urine.

Koo KM, Wee EJH, Trau M.

Biosens Bioelectron. 2017 Mar 15;89(Pt 2):715-720. doi: 10.1016/j.bios.2016.11.024. Epub 2016 Nov 12.

PMID:
27865106
33.

Nanoyeast and Other Cell Envelope Compositions for Protein Studies and Biosensor Applications.

Grewal YS, Shiddiky MJ, Mahler SM, Cangelosi GA, Trau M.

ACS Appl Mater Interfaces. 2016 Nov 16;8(45):30649-30664. Epub 2016 Nov 4. Review.

34.

Toward Precision Medicine: A Cancer Molecular Subtyping Nano-Strategy for RNA Biomarkers in Tumor and Urine.

Koo KM, Wee EJ, Mainwaring PN, Wang Y, Trau M.

Small. 2016 Dec;12(45):6233-6242. doi: 10.1002/smll.201602161. Epub 2016 Sep 26.

PMID:
27717152
35.

A DNA Circuit for IsomiR Detection.

Connolly AR, Hirani R, Ellis AV, Trau M.

Chembiochem. 2016 Nov 17;17(22):2172-2178. doi: 10.1002/cbic.201600452. Epub 2016 Oct 14.

PMID:
27629276
36.

Rapid and Sensitive Fusion Gene Detection in Prostate Cancer Urinary Specimens by Label-Free Surface-enhanced Raman Scattering.

Koo KM, McNamara B, Wee EJH, Wang Y, Trau M.

J Biomed Nanotechnol. 2016 Sep;12(9):1798-805.

PMID:
29345891
37.

A simple, rapid, low-cost technique for naked-eye detection of urine-isolated TMPRSS2:ERG gene fusion RNA.

Koo KM, Wee EJ, Mainwaring PN, Trau M.

Sci Rep. 2016 Jul 29;6:30722. doi: 10.1038/srep30722.

38.

Real time and label free profiling of clinically relevant exosomes.

Sina AA, Vaidyanathan R, Dey S, Carrascosa LG, Shiddiky MJ, Trau M.

Sci Rep. 2016 Jul 28;6:30460. doi: 10.1038/srep30460.

39.

Rapid Molecular Profiling of Myeloproliferative Neoplasms Using Targeted Exon Resequencing of 86 Genes Involved in JAK-STAT Signaling and Epigenetic Regulation.

Magor GW, Tallack MR, Klose NM, Taylor D, Korbie D, Mollee P, Trau M, Perkins AC.

J Mol Diagn. 2016 Sep;18(5):707-718. doi: 10.1016/j.jmoldx.2016.05.006. Epub 2016 Jul 19.

PMID:
27449473
40.

Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumour DNA with SERS Nanotags.

Wee EJ, Wang Y, Tsao SC, Trau M.

Theranostics. 2016 Jun 17;6(10):1506-13. doi: 10.7150/thno.15871. eCollection 2016.

41.

Field Demonstration of a Multiplexed Point-of-Care Diagnostic Platform for Plant Pathogens.

Lau HY, Wang Y, Wee EJ, Botella JR, Trau M.

Anal Chem. 2016 Aug 16;88(16):8074-81. doi: 10.1021/acs.analchem.6b01551. Epub 2016 Jul 27.

PMID:
27403651
42.

Colorimetric TMPRSS2-ERG Gene Fusion Detection in Prostate Cancer Urinary Samples via Recombinase Polymerase Amplification.

Koo KM, Wee EJ, Trau M.

Theranostics. 2016 Jun 15;6(9):1415-24. doi: 10.7150/thno.15250. eCollection 2016.

43.

Amplification-Free Detection of Gene Fusions in Prostate Cancer Urinary Samples Using mRNA-Gold Affinity Interactions.

Koo KM, Carrascosa LG, Shiddiky MJ, Trau M.

Anal Chem. 2016 Jul 5;88(13):6781-8. doi: 10.1021/acs.analchem.6b01182. Epub 2016 Jun 23.

PMID:
27299694
44.

Biosensing made easy with PEG-targeted bi-specific antibodies.

Raftery LJ, Grewal YS, Howard CB, Jones ML, Shiddiky MJ, Carrascosa LG, Thurecht KJ, Mahler SM, Trau M.

Chem Commun (Camb). 2016 Apr 28;52(33):5730-3. doi: 10.1039/c6cc01916a.

PMID:
27045479
45.

Electrochemical detection of protein glycosylation using lectin and protein-gold affinity interactions.

Yadav S, Carrascosa LG, Sina AA, Shiddiky MJ, Hill MM, Trau M.

Analyst. 2016 Apr 21;141(8):2356-61. doi: 10.1039/c6an00528d. Epub 2016 Mar 16.

PMID:
26980140
46.

Phase II Randomized Preoperative Window-of-Opportunity Study of the PI3K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor-Positive Breast Cancer.

Schmid P, Pinder SE, Wheatley D, Macaskill J, Zammit C, Hu J, Price R, Bundred N, Hadad S, Shia A, Sarker SJ, Lim L, Gazinska P, Woodman N, Korbie D, Trau M, Mainwaring P, Gendreau S, Lackner MR, Derynck M, Wilson TR, Butler H, Earl G, Parker P, Purushotham A, Thompson A.

J Clin Oncol. 2016 Jun 10;34(17):1987-94. doi: 10.1200/JCO.2015.63.9179. Epub 2016 Mar 14.

47.

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing.

Wong NC, Pope BJ, Candiloro IL, Korbie D, Trau M, Wong SQ, Mikeska T, Zhang X, Pitman M, Eggers S, Doyle SR, Dobrovic A.

BMC Bioinformatics. 2016 Feb 24;17:98. doi: 10.1186/s12859-016-0950-8.

48.

Accurate and sensitive total genomic DNA methylation analysis from sub-nanogram input with embedded SERS nanotags.

Wang Y, Wee EJ, Trau M.

Chem Commun (Camb). 2016 Feb 28;52(17):3560-3. doi: 10.1039/c6cc00547k. Epub 2016 Feb 4.

PMID:
26841713
49.

Capture and On-chip analysis of Melanoma Cells Using Tunable Surface Shear forces.

Tsao SC, Vaidyanathan R, Dey S, Carrascosa LG, Christophi C, Cebon J, Shiddiky MJ, Behren A, Trau M.

Sci Rep. 2016 Jan 27;6:19709. doi: 10.1038/srep19709.

50.

Poly(A) Extensions of miRNAs for Amplification-Free Electrochemical Detection on Screen-Printed Gold Electrodes.

Koo KM, Carrascosa LG, Shiddiky MJ, Trau M.

Anal Chem. 2016 Feb 16;88(4):2000-5. doi: 10.1021/acs.analchem.5b04795. Epub 2016 Jan 29.

PMID:
26814930

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