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Items: 1 to 50 of 86

1.

Promiscuity analysis of a kinase panel screen with designated p38 alpha inhibitors.

González-Medina M, Miljković F, Haase GS, Drueckes P, Trappe J, Laufer S, Bajorath J.

Eur J Med Chem. 2020 Feb 1;187:112004. doi: 10.1016/j.ejmech.2019.112004. Epub 2019 Dec 20.

PMID:
31881458
2.

A high-throughput screening for inhibitors of riboflavin synthase identifies novel antimicrobial compounds to treat brucellosis.

Serer MI, Carrica MDC, Trappe J, López Romero S, Bonomi HR, Klinke S, Cerutti ML, Goldbaum FA.

FEBS J. 2019 Jul;286(13):2522-2535. doi: 10.1111/febs.14829. Epub 2019 Apr 10.

PMID:
30927485
3.

Description and distribution of Tuberincognitum sp. nov. and Tuberanniae in the Transmexican Volcanic Belt.

Páez CP, Bonito GM, Guevara-Guerrero G, Castellano MA, Garibay-Orijel R, Trappe JM, Rámirez RP.

MycoKeys. 2018 Oct 11;(41):17-27. doi: 10.3897/mycokeys.41.28130. eCollection 2018.

4.

Crested porcupines (Hystrix cristata): mycophagist spore dispersers of the ectomycorrhizal truffle Tuber aestivum.

Ori F, Trappe J, Leonardi M, Iotti M, Pacioni G.

Mycorrhiza. 2018 Aug;28(5-6):561-565. doi: 10.1007/s00572-018-0840-1. Epub 2018 Jun 4.

PMID:
29869187
5.

Tuber aztecorum sp. nov., a truffle species from Mexico belonging to the Maculatum clade (Tuberaceae, Pezizales).

Guevara-Guerrero G, Bonito G, Smith ME, Healy R, Grupe AC II, Cázares E, Castellano MA, Trappe JM.

MycoKeys. 2018 Feb 28;(30):61-72. doi: 10.3897/mycokeys.30.22887. eCollection 2018.

6.

Multigene phylogeny of Endogonales, an early diverging lineage of fungi associated with plants.

Desirò A, Rimington WR, Jacob A, Pol NV, Smith ME, Trappe JM, Bidartondo MI, Bonito G.

IMA Fungus. 2017 Dec;8(2):245-257. doi: 10.5598/imafungus.2017.08.02.03. Epub 2017 Oct 3.

7.

Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region.

Fairhurst RA, Knoepfel T, Leblanc C, Buschmann N, Gaul C, Blank J, Galuba I, Trappe J, Zou C, Voshol J, Genick C, Brunet-Lefeuvre P, Bitsch F, Graus-Porta D, Furet P.

Medchemcomm. 2017 Jun 8;8(8):1604-1613. doi: 10.1039/c7md00213k. eCollection 2017 Aug 1.

8.

A molecular and morphological re-examination of the generic limits of truffles in the tarzetta-geopyxis lineage - Densocarpa, Hydnocystis, and Paurocotylis.

Kumar LM, Smith ME, Nouhra ER, Orihara T, Sandoval Leiva P, Pfister DH, McLaughlin DJ, Trappe JM, Healy RA.

Fungal Biol. 2017 Mar;121(3):264-284. doi: 10.1016/j.funbio.2016.12.004. Epub 2017 Jan 13.

PMID:
28215353
9.

Phylogenetic overview of the genus Genea (Pezizales, Ascomycota) with an emphasis on European taxa.

Alvarado P, Cabero J, Moreno G, Bratek Z, van Vooren N, Kaounas V, Konstantinidis G, Agnello C, Merényi Z, Smith ME, Vizzini A, Trappe JM.

Mycologia. 2016 Mar-Apr;108(2):441-56. doi: 10.3852/15-199. Epub 2016 Jan 6.

PMID:
26740538
10.

Identification and optimisation of a 4',5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors.

Fairhurst RA, Imbach-Weese P, Gerspacher M, Caravatti G, Furet P, Zoller T, Fritsch C, Haasen D, Trappe J, Guthy DA, Arz D, Wirth J.

Bioorg Med Chem Lett. 2015 Sep 1;25(17):3569-74. doi: 10.1016/j.bmcl.2015.06.078. Epub 2015 Jun 27.

PMID:
26206504
11.

Australasian Sequestrate Fungi 19: Hysterangium colossum sp. nov.

Elliott TF, Trappe JM, Weise A.

IMA Fungus. 2015 Jun;6(1):115-7. doi: 10.5598/imafungus.2015.06.01.05. Epub 2015 May 26.

12.

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor.

Karpov AS, Amiri P, Bellamacina C, Bellance MH, Breitenstein W, Daniel D, Denay R, Fabbro D, Fernandez C, Galuba I, Guerro-Lagasse S, Gutmann S, Hinh L, Jahnke W, Klopp J, Lai A, Lindvall MK, Ma S, Möbitz H, Pecchi S, Rummel G, Shoemaker K, Trappe J, Voliva C, Cowan-Jacob SW, Marzinzik AL.

ACS Med Chem Lett. 2015 May 22;6(7):776-81. doi: 10.1021/acsmedchemlett.5b00102. eCollection 2015 Jul 9.

13.

Analyses of Sporocarps, Morphotyped Ectomycorrhizae, Environmental ITS and LSU Sequences Identify Common Genera that Occur at a Periglacial Site.

Jumpponen A, Brown SP, Trappe JM, Cázares E, Strömmer R.

J Fungi (Basel). 2015 May 25;1(1):76-93. doi: 10.3390/jof1010076.

14.

Correction to Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases.

Muth F, Günther M, Bauer SM, Döring E, Fischer S, Maier J, Drückes P, Köppler J, Trappe J, Rothbauer U, Koch P, Laufer SA.

J Med Chem. 2015 Mar 12;58(5):2567. doi: 10.1021/acs.jmedchem.5b00235. Epub 2015 Feb 26. No abstract available.

PMID:
25719747
15.

Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases.

Muth F, Günther M, Bauer SM, Döring E, Fischer S, Maier J, Drückes P, Köppler J, Trappe J, Rothbauer U, Koch P, Laufer SA.

J Med Chem. 2015 Jan 8;58(1):443-56. doi: 10.1021/jm501557a. Epub 2014 Dec 5. Erratum in: J Med Chem. 2015 Mar 12;58(5):2567.

PMID:
25475894
16.

Sequestrate fungi from Patagonian Nothofagus forests: Cystangium (Russulaceae, Basidiomycota).

Trierveiler-Pereira L, Smith ME, Trappe JM, Nouhra ER.

Mycologia. 2015 Jan-Feb;107(1):90-103. doi: 10.3852/13-302. Epub 2014 Sep 17.

PMID:
25232070
17.

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials.

Fritsch C, Huang A, Chatenay-Rivauday C, Schnell C, Reddy A, Liu M, Kauffmann A, Guthy D, Erdmann D, De Pover A, Furet P, Gao H, Ferretti S, Wang Y, Trappe J, Brachmann SM, Maira SM, Wilson C, Boehm M, Garcia-Echeverria C, Chene P, Wiesmann M, Cozens R, Lehar J, Schlegel R, Caravatti G, Hofmann F, Sellers WR.

Mol Cancer Ther. 2014 May;13(5):1117-29. doi: 10.1158/1535-7163.MCT-13-0865. Epub 2014 Mar 7.

18.

Morchella australiana sp. nov., an apparent Australian endemic from New South Wales and Victoria.

Elliott TF, Bougher NL, O'Donnell K, Trappe JM.

Mycologia. 2014 Jan-Feb;106(1):113-8. doi: 10.3852/13-065.

PMID:
24603835
19.

Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers.

Garcia PD, Langowski JL, Wang Y, Chen M, Castillo J, Fanton C, Ison M, Zavorotinskaya T, Dai Y, Lu J, Niu XH, Basham S, Chan J, Yu J, Doyle M, Feucht P, Warne R, Narberes J, Tsang T, Fritsch C, Kauffmann A, Pfister E, Drueckes P, Trappe J, Wilson C, Han W, Lan J, Nishiguchi G, Lindvall M, Bellamacina C, Aycinena JA, Zang R, Holash J, Burger MT.

Clin Cancer Res. 2014 Apr 1;20(7):1834-45. doi: 10.1158/1078-0432.CCR-13-2062. Epub 2014 Jan 28.

20.

Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV.

Namoto K, Sirockin F, Ostermann N, Gessier F, Flohr S, Sedrani R, Gerhartz B, Trappe J, Hassiepen U, Duttaroy A, Ferreira S, Sutton JM, Clark DE, Fenton G, Beswick M, Baeschlin DK.

Bioorg Med Chem Lett. 2014 Feb 1;24(3):731-6. doi: 10.1016/j.bmcl.2013.12.118. Epub 2014 Jan 6.

PMID:
24439847
21.

Targeting Plasmodium PI(4)K to eliminate malaria.

McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, Ibanez M, Kato N, Kuhen KL, Fischli C, Nagle A, Rottmann M, Plouffe DM, Bursulaya B, Meister S, Rameh L, Trappe J, Haasen D, Timmerman M, Sauerwein RW, Suwanarusk R, Russell B, Renia L, Nosten F, Tully DC, Kocken CH, Glynne RJ, Bodenreider C, Fidock DA, Diagana TT, Winzeler EA.

Nature. 2013 Dec 12;504(7479):248-253. doi: 10.1038/nature12782. Epub 2013 Nov 27.

22.

Australasian sequestrate fungi 18: Solioccasus polychromus gen. & sp. nov., a richly colored, tropical to subtropical, hypogeous fungus.

Trappe JM, Castellano MA, Halling RE, Osmundson TW, Binder M, Fechner N, Malajczuk N.

Mycologia. 2013 Jul-Aug;105(4):888-95. doi: 10.3852/12-046. Epub 2013 May 24.

PMID:
23709482
23.

The enigmatic truffle Fevansia aurantiaca is an ectomycorrhizal member of the Albatrellus lineage.

Smith ME, Schell KJ, Castellano MA, Trappe MJ, Trappe JM.

Mycorrhiza. 2013 Nov;23(8):663-8. doi: 10.1007/s00572-013-0502-2. Epub 2013 May 11.

PMID:
23666521
24.

A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore.

Ostermann N, Ruedisser S, Ehrhardt C, Breitenstein W, Marzinzik A, Jacoby E, Vangrevelinghe E, Ottl J, Klumpp M, Hartwieg JC, Cumin F, Hassiepen U, Trappe J, Sedrani R, Geisse S, Gerhartz B, Richert P, Francotte E, Wagner T, Krömer M, Kosaka T, Webb RL, Rigel DF, Maibaum J, Baeschlin DK.

J Med Chem. 2013 Mar 28;56(6):2196-206. doi: 10.1021/jm301706j. Epub 2013 Mar 15.

PMID:
23360239
25.

Historical biogeography and diversification of truffles in the Tuberaceae and their newly identified southern hemisphere sister lineage.

Bonito G, Smith ME, Nowak M, Healy RA, Guevara G, Cázares E, Kinoshita A, Nouhra ER, Domínguez LS, Tedersoo L, Murat C, Wang Y, Moreno BA, Pfister DH, Nara K, Zambonelli A, Trappe JM, Vilgalys R.

PLoS One. 2013;8(1):e52765. doi: 10.1371/journal.pone.0052765. Epub 2013 Jan 2.

26.

High diversity and widespread occurrence of mitotic spore mats in ectomycorrhizal Pezizales.

Healy RA, Smith ME, Bonito GM, Pfister DH, Ge ZW, Guevara GG, Williams G, Stafford K, Kumar L, Lee T, Hobart C, Trappe J, Vilgalys R, McLaughlin DJ.

Mol Ecol. 2013 Mar;22(6):1717-32. doi: 10.1111/mec.12135. Epub 2012 Dec 3.

PMID:
23205556
27.

The Substrate-Activity-Screening methodology applied to receptor tyrosine kinases: a proof-of-concept study.

Chapelat J, Berst F, Marzinzik AL, Moebitz H, Drueckes P, Trappe J, Fabbro D, Seebach D.

Eur J Med Chem. 2012 Nov;57:1-9. doi: 10.1016/j.ejmech.2012.08.038. Epub 2012 Sep 4.

PMID:
23041456
28.

New North American truffles (Tuber spp.) and their ectomycorrhizal associations.

Guevara G, Bonito G, Trappe JM, Cázares E, Williams G, Healy RA, Schadt C, Vilgalys R.

Mycologia. 2013 Jan-Feb;105(1):194-209. doi: 10.3852/12-087. Epub 2012 Sep 6.

PMID:
22962353
29.

Nitrogen content, amino acid composition and digestibility of fungi from a nutritional perspective in animal mycophagy.

Wallis IR, Claridge AW, Trappe JM.

Fungal Biol. 2012 May;116(5):590-602. doi: 10.1016/j.funbio.2012.02.007. Epub 2012 Mar 3.

PMID:
22559919
30.

Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes.

Sutton JM, Clark DE, Dunsdon SJ, Fenton G, Fillmore A, Harris NV, Higgs C, Hurley CA, Krintel SL, MacKenzie RE, Duttaroy A, Gangl E, Maniara W, Sedrani R, Namoto K, Ostermann N, Gerhartz B, Sirockin F, Trappe J, Hassiepen U, Baeschlin DK.

Bioorg Med Chem Lett. 2012 Feb 1;22(3):1464-8. doi: 10.1016/j.bmcl.2011.11.054. Epub 2011 Nov 20. Erratum in: Bioorg Med Chem Lett. 2012 Mar 15;22(6):2359.

PMID:
22177783
31.

7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.

Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F.

J Med Chem. 2012 Jan 12;55(1):403-13. doi: 10.1021/jm201286z. Epub 2012 Jan 3.

32.

Substrate profiling of IGF-1R and InsR: identification of a potent pentamer substrate.

Chapelat J, Berst F, Marzinzik AL, Moebitz H, Drueckes P, Fabbro D, Trappe J, Seebach D.

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7030-3. doi: 10.1016/j.bmcl.2011.09.101. Epub 2011 Sep 29.

PMID:
22004721
33.

Cryptolepiota, a new sequestrate genus in the Agaricaceae with evidence for adaptive radiation in western North America.

Kropp BR, Albee-Scott S, Castellano MA, Trappe JM.

Mycologia. 2012 Jan-Feb;104(1):164-74. doi: 10.3852/11-046. Epub 2011 Aug 9.

PMID:
21828217
34.

The dawn of symbiosis between plants and fungi.

Bidartondo MI, Read DJ, Trappe JM, Merckx V, Ligrone R, Duckett JG.

Biol Lett. 2011 Aug 23;7(4):574-7. doi: 10.1098/rsbl.2010.1203. Epub 2011 Mar 9.

35.

Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing.

Fedorov O, Huber K, Eisenreich A, Filippakopoulos P, King O, Bullock AN, Szklarczyk D, Jensen LJ, Fabbro D, Trappe J, Rauch U, Bracher F, Knapp S.

Chem Biol. 2011 Jan 28;18(1):67-76. doi: 10.1016/j.chembiol.2010.11.009.

36.

Terfezia disappears from the American truffle mycota as two new genera and Mattirolomyces species emerge.

Kovács GM, Trappe JM, Alsheikh AM, Hansen K, Healy RA, Vági P.

Mycologia. 2011 Jul-Aug;103(4):831-40. doi: 10.3852/10-273. Epub 2011 Jan 24.

PMID:
21262987
37.

Kinase inhibition by deoxy analogues of the resorcylic lactone L-783277.

Liniger M, Neuhaus C, Hofmann T, Fransioli-Ignazio L, Jordi M, Drueckes P, Trappe J, Fabbro D, Altmann KH.

ACS Med Chem Lett. 2010 Oct 20;2(1):22-7. doi: 10.1021/ml1001807. eCollection 2011 Jan 13.

38.

James Wessell Gerdemann, 1921-2008.

Trappe JM.

Mycologia. 2010 Nov-Dec;102(6):1518-22. No abstract available.

PMID:
21043065
39.

A global meta-analysis of Tuber ITS rDNA sequences: species diversity, host associations and long-distance dispersal.

Bonito GM, Gryganskyi AP, Trappe JM, Vilgalys R.

Mol Ecol. 2010 Nov;19(22):4994-5008. doi: 10.1111/j.1365-294X.2010.04855.x. Epub 2010 Oct 12.

PMID:
21040049
40.

Kalapuya brunnea gen. & sp. nov. and its relationship to the other sequestrate genera in Morchellaceae.

Trappe MJ, Trappe JM, Bonito GM.

Mycologia. 2010 Sep-Oct;102(5):1058-65. doi: 10.3852/09-232.

PMID:
20943505
41.

Improved resolution of major clades within Tuber and taxonomy of species within the Tuber gibbosum complex.

Bonito G, Trappe JM, Rawlinson P, Vilgalys R.

Mycologia. 2010 Sep-Oct;102(5):1042-57. doi: 10.3852/09-213.

PMID:
20943504
42.

Phylogenetic relationships of the Gomphales based on nuc-25S-rDNA, mit-12S-rDNA, and mit-atp6-DNA combined sequences.

Giachini AJ, Hosaka K, Nouhra E, Spatafora J, Trappe JM.

Fungal Biol. 2010 Feb-Mar;114(2-3):224-34. doi: 10.1016/j.funbio.2010.01.002. Epub 2010 Jan 28.

PMID:
20943133
43.

Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805.

Baffert F, Régnier CH, De Pover A, Pissot-Soldermann C, Tavares GA, Blasco F, Brueggen J, Chène P, Drueckes P, Erdmann D, Furet P, Gerspacher M, Lang M, Ledieu D, Nolan L, Ruetz S, Trappe J, Vangrevelinghe E, Wartmann M, Wyder L, Hofmann F, Radimerski T.

Mol Cancer Ther. 2010 Jul;9(7):1945-55. doi: 10.1158/1535-7163.MCT-10-0053. Epub 2010 Jun 29.

44.

Suillus quiescens, a new species commonly found in the spore bank in California and Oregon.

Bruns TD, Grubisha LC, Trappe JM, Kerekes JF, Vellinga EC.

Mycologia. 2010 Mar-Apr;102(2):438-46.

PMID:
20361510
45.

The hidden life of truffles.

Trappe JM, Claridge AW.

Sci Am. 2010 Apr;302(4):78-82, 84. No abstract available.

PMID:
20349580
46.

2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors.

Gerspacher M, Furet P, Pissot-Soldermann C, Gaul C, Holzer P, Vangrevelinghe E, Lang M, Erdmann D, Radimerski T, Regnier CH, Chene P, De Pover A, Hofmann F, Baffert F, Buhl T, Aichholz R, Blasco F, Endres R, Trappe J, Drueckes P.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1724-7. doi: 10.1016/j.bmcl.2010.01.069. Epub 2010 Jan 21.

PMID:
20138510
47.

Extended kinase profile and properties of the protein kinase inhibitor nilotinib.

Manley PW, Drueckes P, Fendrich G, Furet P, Liebetanz J, Martiny-Baron G, Mestan J, Trappe J, Wartmann M, Fabbro D.

Biochim Biophys Acta. 2010 Mar;1804(3):445-53. doi: 10.1016/j.bbapap.2009.11.008. Epub 2009 Nov 14.

PMID:
19922818
48.

The Ascomycota tree of life: a phylum-wide phylogeny clarifies the origin and evolution of fundamental reproductive and ecological traits.

Schoch CL, Sung GH, López-Giráldez F, Townsend JP, Miadlikowska J, Hofstetter V, Robbertse B, Matheny PB, Kauff F, Wang Z, Gueidan C, Andrie RM, Trippe K, Ciufetti LM, Wynns A, Fraker E, Hodkinson BP, Bonito G, Groenewald JZ, Arzanlou M, de Hoog GS, Crous PW, Hewitt D, Pfister DH, Peterson K, Gryzenhout M, Wingfield MJ, Aptroot A, Suh SO, Blackwell M, Hillis DM, Griffith GW, Castlebury LA, Rossman AY, Lumbsch HT, Lücking R, Büdel B, Rauhut A, Diederich P, Ertz D, Geiser DM, Hosaka K, Inderbitzin P, Kohlmeyer J, Volkmann-Kohlmeyer B, Mostert L, O'Donnell K, Sipman H, Rogers JD, Shoemaker RA, Sugiyama J, Summerbell RC, Untereiner W, Johnston PR, Stenroos S, Zuccaro A, Dyer PS, Crittenden PD, Cole MS, Hansen K, Trappe JM, Yahr R, Lutzoni F, Spatafora JW.

Syst Biol. 2009 Apr;58(2):224-39. doi: 10.1093/sysbio/syp020. Epub 2009 Jun 4.

PMID:
20525580
49.

Diversity and habitat relationships of hypogeous fungi. III. Factors influencing the occurrence of fire-adapted species.

Claridge AW, Trappe JM, Mills DJ, Claridge DL.

Mycol Res. 2009 Jun-Jul;113(Pt 6-7):792-801. doi: 10.1016/j.mycres.2009.02.014. Epub 2009 Mar 6.

PMID:
19269321
50.

Imaia, a new truffle genus to accommodate Terfezia gigantea.

Kovács GM, Trappe JM, Alsheikh AM, Bóka K, Elliott TF.

Mycologia. 2008 Nov-Dec;100(6):930-9.

PMID:
19202847

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