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Items: 8

1.

In vitro-In vivo extrapolation of key transporter activity at the blood-brain barrier.

Trapa PE, Troutman MD, Lau TY, Wager TT, Maurer TS, Patel NC, West MA, Umland JP, Carlo AA, Feng B, Liras JL.

Drug Metab Dispos. 2019 Jan 25. pii: dmd.118.083279. doi: 10.1124/dmd.118.083279. [Epub ahead of print]

2.

Insights from mathematical modeling for convection-enhanced intraputamenal delivery of GDNF.

Belova E, Shaffer CL, Trapa PE.

Med Biol Eng Comput. 2017 Dec;55(12):2069-2077. doi: 10.1007/s11517-017-1650-x. Epub 2017 May 11.

3.

In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey.

Trapa PE, Beaumont K, Atkinson K, Eng H, King-Ahmad A, Scott DO, Maurer TS, Di L.

J Pharm Sci. 2017 Mar;106(3):898-905. doi: 10.1016/j.xphs.2016.12.001. Epub 2016 Dec 18.

PMID:
27998705
4.

Insights From an Integrated Physiologically Based Pharmacokinetic Model for Brain Penetration.

Trapa PE, Belova E, Liras JL, Scott DO, Steyn SJ.

J Pharm Sci. 2016 Feb;105(2):965-971. doi: 10.1016/j.xphs.2015.12.005.

PMID:
26869440
5.

Enhancing ketamine translational pharmacology via receptor occupancy normalization.

Shaffer CL, Osgood SM, Smith DL, Liu J, Trapa PE.

Neuropharmacology. 2014 Nov;86:174-80. doi: 10.1016/j.neuropharm.2014.07.008. Epub 2014 Jul 22.

PMID:
25063581
6.

Permeability comparison between hepatocyte and low efflux MDCKII cell monolayer.

Li R, Bi YA, Lai Y, Sugano K, Steyn SJ, Trapa PE, Di L.

AAPS J. 2014 Jul;16(4):802-9. doi: 10.1208/s12248-014-9616-5. Epub 2014 May 23.

7.

Impact of recovery on fraction unbound using equilibrium dialysis.

Di L, Umland JP, Trapa PE, Maurer TS.

J Pharm Sci. 2012 Mar;101(3):1327-35. doi: 10.1002/jps.23013. Epub 2011 Dec 9.

PMID:
22161810
8.

Nash equilibria for an evolutionary language game.

Trapa PE, Nowak MA.

J Math Biol. 2000 Aug;41(2):172-88.

PMID:
11039696

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