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Items: 1 to 50 of 110


Tissue-engineered transcatheter vein valve.

Syedain ZH, Jenson AC, Patel PS, Feagler C, Bahmer L, Faizer R, Tranquillo RT.

Biomaterials. 2019 Sep;216:119229. doi: 10.1016/j.biomaterials.2019.119229. Epub 2019 May 31.


Shear Conditioning of Adipose Stem Cells for Reduced Platelet Binding to Engineered Vascular Grafts.

La A, Tranquillo RT.

Tissue Eng Part A. 2018 Aug;24(15-16):1242-1250. doi: 10.1089/ten.TEA.2017.0475. Epub 2018 Mar 20.


A completely biological "off-the-shelf" arteriovenous graft that recellularizes in baboons.

Syedain ZH, Graham ML, Dunn TB, O'Brien T, Johnson SL, Schumacher RJ, Tranquillo RT.

Sci Transl Med. 2017 Nov 1;9(414). pii: eaan4209. doi: 10.1126/scitranslmed.aan4209.


A cardiac patch from aligned microvessel and cardiomyocyte patches.

Schaefer JA, Guzman PA, Riemenschneider SB, Kamp TJ, Tranquillo RT.

J Tissue Eng Regen Med. 2018 Feb;12(2):546-556. doi: 10.1002/term.2568. Epub 2017 Nov 23.


Corrigendum: Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs.

Syedain Z, Reimer J, Lahti M, Berry J, Johnson S, Bianco R, Tranquillo RT.

Nat Commun. 2017 Jan 17;8:14297. doi: 10.1038/ncomms14297. No abstract available.


Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs.

Syedain Z, Reimer J, Lahti M, Berry J, Johnson S, Tranquillo RT.

Nat Commun. 2016 Sep 27;7:12951. doi: 10.1038/ncomms12951.


Inosculation and perfusion of pre-vascularized tissue patches containing aligned human microvessels after myocardial infarction.

Riemenschneider SB, Mattia DJ, Wendel JS, Schaefer JA, Ye L, Guzman PA, Tranquillo RT.

Biomaterials. 2016 Aug;97:51-61. doi: 10.1016/j.biomaterials.2016.04.031. Epub 2016 Apr 26.


Swelling of Collagen-Hyaluronic Acid Co-Gels: An In Vitro Residual Stress Model.

Lai VK, Nedrelow DS, Lake SP, Kim B, Weiss EM, Tranquillo RT, Barocas VH.

Ann Biomed Eng. 2016 Oct;44(10):2984-2993. doi: 10.1007/s10439-016-1636-0. Epub 2016 May 5.


Effects of Intermittent and Incremental Cyclic Stretch on ERK Signaling and Collagen Production in Engineered Tissue.

Schmidt JB, Chen K, Tranquillo RT.

Cell Mol Bioeng. 2016 Mar 1;9(1):55-64. Epub 2015 Aug 11.


Tissue Contraction Force Microscopy for Optimization of Engineered Cardiac Tissue.

Schaefer JA, Tranquillo RT.

Tissue Eng Part C Methods. 2016 Jan;22(1):76-83. doi: 10.1089/ten.TEC.2015.0220. Epub 2015 Dec 14.


6-month aortic valve implantation of an off-the-shelf tissue-engineered valve in sheep.

Syedain Z, Reimer J, Schmidt J, Lahti M, Berry J, Bianco R, Tranquillo RT.

Biomaterials. 2015 Dec;73:175-84. doi: 10.1016/j.biomaterials.2015.09.016. Epub 2015 Sep 11.


Functional Effects of a Tissue-Engineered Cardiac Patch From Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Rat Infarct Model.

Wendel JS, Ye L, Tao R, Zhang J, Zhang J, Kamp TJ, Tranquillo RT.

Stem Cells Transl Med. 2015 Nov;4(11):1324-32. doi: 10.5966/sctm.2015-0044. Epub 2015 Sep 14.


Cyclic Stretch and Perfusion Bioreactor for Conditioning Large Diameter Engineered Tissue Tubes.

Schmidt JB, Tranquillo RT.

Ann Biomed Eng. 2016 May;44(5):1785-97. doi: 10.1007/s10439-015-1437-x. Epub 2015 Aug 26.


Pediatric tubular pulmonary heart valve from decellularized engineered tissue tubes.

Reimer JM, Syedain ZH, Haynie BH, Tranquillo RT.

Biomaterials. 2015 Sep;62:88-94. doi: 10.1016/j.biomaterials.2015.05.009. Epub 2015 May 16.


Automated image analysis programs for the quantification of microvascular network characteristics.

Morin KT, Carlson PD, Tranquillo RT.

Methods. 2015 Aug;84:76-83. doi: 10.1016/j.ymeth.2015.03.014. Epub 2015 Apr 2. Review.


Cells for tissue engineering of cardiac valves.

Jana S, Tranquillo RT, Lerman A.

J Tissue Eng Regen Med. 2016 Oct;10(10):804-824. doi: 10.1002/term.2010. Epub 2015 Feb 25. Review.


Influence of culture conditions and extracellular matrix alignment on human mesenchymal stem cells invasion into decellularized engineered tissues.

Weidenhamer NK, Moore DL, Lobo FL, Klair NT, Tranquillo RT.

J Tissue Eng Regen Med. 2015 May;9(5):605-18. doi: 10.1002/term.1974. Epub 2015 Jan 2.


A mathematical model for understanding fluid flow through engineered tissues containing microvessels.

Morin KT, Lenz MS, Labat CA, Tranquillo RT.

J Biomech Eng. 2015 May;137(5):051003. doi: 10.1115/1.4029236. Epub 2015 Feb 24.


Combating Adaptation to Cyclic Stretching By Prolonging Activation of Extracellular Signal-Regulated Kinase.

Weinbaum JS, Schmidt JB, Tranquillo RT.

Cell Mol Bioeng. 2013 Sep;6(3):279-286.


Blood outgrowth endothelial cells alter remodeling of completely biological engineered grafts implanted into the sheep femoral artery.

Meier LA, Syedain ZH, Lahti MT, Johnson SS, Chen MH, Hebbel RP, Tranquillo RT.

J Cardiovasc Transl Res. 2014 Mar;7(2):242-9. doi: 10.1007/s12265-013-9539-z. Epub 2014 Jan 16.


Implantation of completely biological engineered grafts following decellularization into the sheep femoral artery.

Syedain ZH, Meier LA, Lahti MT, Johnson SL, Tranquillo RT.

Tissue Eng Part A. 2014 Jun;20(11-12):1726-34. doi: 10.1089/ten.TEA.2013.0550. Epub 2014 Feb 25.


Functional consequences of a tissue-engineered myocardial patch for cardiac repair in a rat infarct model.

Wendel JS, Ye L, Zhang P, Tranquillo RT, Zhang JJ.

Tissue Eng Part A. 2014 Apr;20(7-8):1325-35. doi: 10.1089/ten.TEA.2013.0312. Epub 2014 Feb 6.


Engineered microvessels with strong alignment and high lumen density via cell-induced fibrin gel compaction and interstitial flow.

Morin KT, Dries-Devlin JL, Tranquillo RT.

Tissue Eng Part A. 2014 Feb;20(3-4):553-65. doi: 10.1089/ten.TEA.2013.0262. Epub 2013 Nov 14.


Aligned human microvessels formed in 3D fibrin gel by constraint of gel contraction.

Morin KT, Smith AO, Davis GE, Tranquillo RT.

Microvasc Res. 2013 Nov;90:12-22. doi: 10.1016/j.mvr.2013.07.010. Epub 2013 Aug 9.


Tubular heart valves from decellularized engineered tissue.

Syedain ZH, Meier LA, Reimer JM, Tranquillo RT.

Ann Biomed Eng. 2013 Dec;41(12):2645-54. doi: 10.1007/s10439-013-0872-9. Epub 2013 Jul 30.


In vitro models of angiogenesis and vasculogenesis in fibrin gel.

Morin KT, Tranquillo RT.

Exp Cell Res. 2013 Oct 1;319(16):2409-17. doi: 10.1016/j.yexcr.2013.06.006. Epub 2013 Jun 22. Review.


A multiscale approach to modeling the passive mechanical contribution of cells in tissues.

Lai VK, Hadi MF, Tranquillo RT, Barocas VH.

J Biomech Eng. 2013 Jul 1;135(7):71007. doi: 10.1115/1.4024350.


Influence of cyclic mechanical stretch and tissue constraints on cellular and collagen alignment in fibroblast-derived cell sheets.

Weidenhamer NK, Tranquillo RT.

Tissue Eng Part C Methods. 2013 May;19(5):386-95. doi: 10.1089/ten.TEC.2012.0423. Epub 2013 Jan 8.


Decellularized tissue-engineered heart valve leaflets with recellularization potential.

Syedain ZH, Bradee AR, Kren S, Taylor DA, Tranquillo RT.

Tissue Eng Part A. 2013 Mar;19(5-6):759-69. doi: 10.1089/ten.TEA.2012.0365. Epub 2012 Dec 10.


Microstructural and mechanical differences between digested collagen-fibrin co-gels and pure collagen and fibrin gels.

Lai VK, Frey CR, Kerandi AM, Lake SP, Tranquillo RT, Barocas VH.

Acta Biomater. 2012 Nov;8(11):4031-42. doi: 10.1016/j.actbio.2012.07.010. Epub 2012 Jul 22.


Mechanical behavior of collagen-fibrin co-gels reflects transition from series to parallel interactions with increasing collagen content.

Lai VK, Lake SP, Frey CR, Tranquillo RT, Barocas VH.

J Biomech Eng. 2012 Jan;134(1):011004. doi: 10.1115/1.4005544.


Hypoxic culture and insulin yield improvements to fibrin-based engineered tissue.

Bjork JW, Meier LA, Johnson SL, Syedain ZH, Tranquillo RT.

Tissue Eng Part A. 2012 Apr;18(7-8):785-95. doi: 10.1089/ten.TEA.2011.0017. Epub 2011 Dec 5.


Guided sprouting from endothelial spheroids in fibrin gels aligned by magnetic fields and cell-induced gel compaction.

Morin KT, Tranquillo RT.

Biomaterials. 2011 Sep;32(26):6111-8. doi: 10.1016/j.biomaterials.2011.05.018. Epub 2011 Jun 1.


Shear stress responses of adult blood outgrowth endothelial cells seeded on bioartificial tissue.

Ahmann KA, Johnson SL, Hebbel RP, Tranquillo RT.

Tissue Eng Part A. 2011 Oct;17(19-20):2511-21. doi: 10.1089/ten.TEA.2011.0055. Epub 2011 Jul 1.


TGF-β1 diminishes collagen production during long-term cyclic stretching of engineered connective tissue: implication of decreased ERK signaling.

Syedain ZH, Tranquillo RT.

J Biomech. 2011 Mar 15;44(5):848-55. doi: 10.1016/j.jbiomech.2010.12.007. Epub 2011 Jan 20.


Ruthenium-catalyzed photo cross-linking of fibrin-based engineered tissue.

Bjork JW, Johnson SL, Tranquillo RT.

Biomaterials. 2011 Apr;32(10):2479-88. doi: 10.1016/j.biomaterials.2010.12.010. Epub 2010 Dec 31.


Initial fiber alignment pattern alters extracellular matrix synthesis in fibroblast-populated fibrin gel cruciforms and correlates with predicted tension.

Sander EA, Barocas VH, Tranquillo RT.

Ann Biomed Eng. 2011 Feb;39(2):714-29. doi: 10.1007/s10439-010-0192-2. Epub 2010 Oct 29.


Implantable arterial grafts from human fibroblasts and fibrin using a multi-graft pulsed flow-stretch bioreactor with noninvasive strength monitoring.

Syedain ZH, Meier LA, Bjork JW, Lee A, Tranquillo RT.

Biomaterials. 2011 Jan;32(3):714-22. doi: 10.1016/j.biomaterials.2010.09.019. Epub 2010 Oct 8.


Fibrin degradation enhances vascular smooth muscle cell proliferation and matrix deposition in fibrin-based tissue constructs fabricated in vitro.

Ahmann KA, Weinbaum JS, Johnson SL, Tranquillo RT.

Tissue Eng Part A. 2010 Oct;16(10):3261-70. doi: 10.1089/ten.TEA.2009.0708.


Fusion of concentrically layered tubular tissue constructs increases burst strength.

Huynh TN, Tranquillo RT.

Ann Biomed Eng. 2010 Jun;38(6):2226-36. doi: 10.1007/s10439-010-0045-z. Epub 2010 Apr 30.


Image-based multiscale structural models of fibrous engineered tissues.

Sander EA, Tranquillo RT, Barocas VH.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4270-2. doi: 10.1109/IEMBS.2009.5334586.


Image-based multiscale modeling predicts tissue-level and network-level fiber reorganization in stretched cell-compacted collagen gels.

Sander EA, Stylianopoulos T, Tranquillo RT, Barocas VH.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17675-80. doi: 10.1073/pnas.0903716106. Epub 2009 Oct 1.


Controlled compaction with ruthenium-catalyzed photochemical cross-linking of fibrin-based engineered connective tissue.

Syedain ZH, Bjork J, Sando L, Tranquillo RT.

Biomaterials. 2009 Dec;30(35):6695-701. doi: 10.1016/j.biomaterials.2009.08.039. Epub 2009 Sep 25.


Monitoring collagen transcription by vascular smooth muscle cells in fibrin-based tissue constructs.

Weinbaum JS, Qi J, Tranquillo RT.

Tissue Eng Part C Methods. 2010 Jun;16(3):459-67. doi: 10.1089/ten.TEC.2009.0112.


Planar biaxial mechanical behavior of bioartificial tissues possessing prescribed fiber alignment.

Jhun CS, Evans MC, Barocas VH, Tranquillo RT.

J Biomech Eng. 2009 Aug;131(8):081006. doi: 10.1115/1.3148194.


Transmural flow bioreactor for vascular tissue engineering.

Bjork JW, Tranquillo RT.

Biotechnol Bioeng. 2009 Dec 15;104(6):1197-206. doi: 10.1002/bit.22475.


The impact of biomechanics in tissue engineering and regenerative medicine.

Butler DL, Goldstein SA, Guldberg RE, Guo XE, Kamm R, Laurencin CT, McIntire LV, Mow VC, Nerem RM, Sah RL, Soslowsky LJ, Spilker RL, Tranquillo RT.

Tissue Eng Part B Rev. 2009 Dec;15(4):477-84. doi: 10.1089/ten.TEB.2009.0340. Review.


Controlled cyclic stretch bioreactor for tissue-engineered heart valves.

Syedain ZH, Tranquillo RT.

Biomaterials. 2009 Sep;30(25):4078-84. doi: 10.1016/j.biomaterials.2009.04.027. Epub 2009 May 26.


Image-based biomechanics of collagen-based tissue equivalents.

Sander EA, Stylianopoulos T, Tranquillo RT, Barocas VH.

IEEE Eng Med Biol Mag. 2009 May-Jun;28(3):10-8. doi: 10.1109/MEMB.2009.932486. No abstract available.

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