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A pilot trial of pembrolizumab plus prostatic cryotherapy for men with newly diagnosed oligometastatic hormone-sensitive prostate cancer.

Ross AE, Hurley PJ, Tran PT, Rowe SP, Benzon B, Neal TO, Chapman C, Harb R, Milman Y, Trock BJ, Drake CG, Antonarakis ES.

Prostate Cancer Prostatic Dis. 2019 Oct 14. doi: 10.1038/s41391-019-0176-8. [Epub ahead of print]


Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.

Huan LC, Tran PT, Phuong CV, Duc PH, Anh DT, Hai PT, Huong LTT, Thuan NT, Lee HJ, Park EJ, Kang JS, Linh NP, Hieu TT, Oanh DTK, Han SB, Nam NH.

Bioorg Chem. 2019 Nov;92:103202. doi: 10.1016/j.bioorg.2019.103202. Epub 2019 Aug 14.


Prediction of AChE-ligand affinity using the umbrella sampling simulation.

Lan NT, Vu KB, Dao Ngoc MK, Tran PT, Hiep DM, Tung NT, Ngo ST.

J Mol Graph Model. 2019 Dec;93:107441. doi: 10.1016/j.jmgm.2019.107441. Epub 2019 Aug 27.


Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma.

Jafarnejad M, Sové RJ, Danilova L, Mirando AC, Zhang Y, Yarchoan M, Tran PT, Pandey NB, Fertig EJ, Popel AS.

NPJ Syst Biol Appl. 2019 Aug 16;5:29. doi: 10.1038/s41540-019-0107-2. eCollection 2019.


Radiation Therapy in the Definitive Management of Oligometastatic Prostate Cancer: The Johns Hopkins Experience.

Deek MP, Yu C, Phillips R, Song DY, Deville C, Greco S, DeWeese TL, Antonarakis ES, Markowski M, Paller C, Denmeade S, Carducci M, Walsh PC, Pienta KJ, Eisenberger M, Tran PT.

Int J Radiat Oncol Biol Phys. 2019 Aug 13. pii: S0360-3016(19)33641-7. doi: 10.1016/j.ijrobp.2019.08.008. [Epub ahead of print]


Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer's Agents by Structure-Based Design.

Hoang VH, Ngo VTH, Cui M, Manh NV, Tran PT, Ann J, Ha HJ, Kim H, Choi K, Kim YH, Chang H, Macalino SJY, Lee J, Choi S, Lee J.

J Med Chem. 2019 Sep 12;62(17):8011-8027. doi: 10.1021/acs.jmedchem.9b00751. Epub 2019 Aug 27.


The Effects of 2',4'-Dihydroxy-6'-methoxy-3',5'- dimethylchalcone from Cleistocalyx operculatus Buds on Human Pancreatic Cancer Cell Lines.

Tuan HN, Minh BH, Tran PT, Lee JH, Oanh HV, Ngo QMT, Nguyen YN, Lien PTK, Tran MH.

Molecules. 2019 Jul 11;24(14). pii: E2538. doi: 10.3390/molecules24142538.


Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C.

Kendrick AA, Dickey AM, Redwine WB, Tran PT, Vaites LP, Dzieciatkowska M, Harper JW, Reck-Peterson SL.

J Cell Biol. 2019 Sep 2;218(9):2982-3001. doi: 10.1083/jcb.201812170. Epub 2019 Jul 18.


Modified Folfox6 as Adjuvant Chemotherapy in Vietnamese Patients With Colorectal Cancer.

Nguyen TQ, Bui TO, Tran PT, Tran VT, Nguyen VH, Chu QH, Bui TAT, Le NQ, Le VQ, Dao VT.

Cancer Control. 2019 Jan-Dec;26(1):1073274819864111. doi: 10.1177/1073274819864111.


α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors.

van Hout M, Valdes A, Christensen SB, Tran PT, Watkins M, Gajewiak J, Jensen AA, Olivera BM, McIntosh JM.

Neuropharmacology. 2019 Oct;157:107691. doi: 10.1016/j.neuropharm.2019.107691. Epub 2019 Jun 28.


A phase II randomized placebo-controlled double-blind study of salvage radiation therapy plus placebo versus SRT plus enzalutamide with high-risk PSA-recurrent prostate cancer after radical prostatectomy (SALV-ENZA).

Kapoor R, Deek MP, McIntyre R, Raman N, Kummerlowe M, Chen I, Gaver M, Wang H, Denmeade S, Lotan T, Paller C, Markowski M, Carducci M, Eisenberger M, Beer TM, Song DY, DeWeese TL, Hearn JW, Greco S, DeVille C, Desai NB, Heath EI, Liauw S, Spratt DE, Hung AY, Antonarakis ES, Tran PT.

BMC Cancer. 2019 Jun 13;19(1):572. doi: 10.1186/s12885-019-5805-z.


Characterization of a carbapenem- and colistin-resistant Enterobacter cloacae carrying Tn6901 in bla NDM-1 genomic context.

Le-Ha TD, Le L, Le-Vo HN, Anda M, Motooka D, Nakamura S, Tran LK, Tran PT, Iida T, Cao V.

Infect Drug Resist. 2019 Apr 3;12:733-739. doi: 10.2147/IDR.S194495. eCollection 2019.


Optimizing the Timing of Salvage Postprostatectomy Radiotherapy and the Use of Concurrent Hormonal Therapy for Prostate Cancer.

Kishan AU, Tendulkar RD, Tran PT, Parker CC, Nguyen PL, Stephenson AJ, Carrie C.

Eur Urol Oncol. 2018 May;1(1):3-18. doi: 10.1016/j.euo.2018.02.008. Epub 2018 May 15. Review.


Prostate-only Versus Whole-pelvis Radiation with or Without a Brachytherapy Boost for Gleason Grade Group 5 Prostate Cancer: A Retrospective Analysis.

Sandler KA, Cook RR, Ciezki JP, Ross AE, Pomerantz MM, Nguyen PL, Shaikh T, Tran PT, Stock RG, Merrick GS, Demanes DJ, Spratt DE, Abu-Isa EI, Wedde TB, Lilleby W, Krauss DJ, Shaw GK, Alam R, Reddy CA, Song DY, Klein EA, Stephenson AJ, Tosoian JJ, Hegde JV, Yoo SM, Fiano R, D'Amico AV, Nickols NG, Aronson WJ, Sadeghi A, Greco SC, Deville C Jr, McNutt T, DeWeese TL, Reiter RE, Said JW, Steinberg ML, Horwitz EM, Kupelian PA, King CR, Kishan AU.

Eur Urol. 2019 Apr 13. pii: S0302-2838(19)30208-8. doi: 10.1016/j.eururo.2019.03.022. [Epub ahead of print]


Ethanol extract of Polyscias fruticosa leaves suppresses RANKL-mediated osteoclastogenesis in vitro and LPS-induced bone loss in vivo.

Tran PT, Dang NH, Kim O, Van Cuong P, Dat NT, Hwangbo C, Van Minh C, Lee JH.

Phytomedicine. 2019 Jun;59:152908. doi: 10.1016/j.phymed.2019.152908. Epub 2019 Apr 2.


Diterpenoids isolated from the root of Salvia miltiorrhiza and their anti-inflammatory activity.

Ngo TM, Tran PT, Hoang LS, Lee JH, Min BS, Kim JA.

Nat Prod Res. 2019 Apr 9:1-7. doi: 10.1080/14786419.2019.1596098. [Epub ahead of print]


Bittersweet tumor development and progression: Emerging roles of epithelial plasticity glycosylations.

Phillips RM, Lam C, Wang H, Tran PT.

Adv Cancer Res. 2019;142:23-62. doi: 10.1016/bs.acr.2019.01.002. Epub 2019 Feb 27.


Secrecy Performance of TAS/SC-Based Multi-Hop Harvest-to-Transmit Cognitive WSNs Under Joint Constraint of Interference and Hardware Imperfection.

Tin PT, Minh Nam P, Trung Duy T, Tran PT, Voznak M.

Sensors (Basel). 2019 Mar 7;19(5). pii: E1160. doi: 10.3390/s19051160.


Verrucous melanoma masquerading as a seborrheic keratosis.

Tran PT, Truong AK, Munday W, Alexanian S, Levins P.

Dermatol Online J. 2019 Feb 15;25(2). pii: 13030/qt1m07k7fm.


Quantifying Tubulin Concentration and Microtubule Number Throughout the Fission Yeast Cell Cycle.

Loiodice I, Janson ME, Tavormina P, Schaub S, Bhatt D, Cochran R, Czupryna J, Fu C, Tran PT.

Biomolecules. 2019 Mar 4;9(3). pii: E86. doi: 10.3390/biom9030086.


Immunomodulatory Effects of Stereotactic Body Radiation Therapy: Preclinical Insights and Clinical Opportunities.

Marciscano AE, Haimovitz-Friedman A, Lee P, Tran PT, Tomé WA, Guha C, Spring Kong FM, Sahgal A, El Naqa I, Rimner A, Marks LB, Formenti SC, DeWeese TL.

Int J Radiat Oncol Biol Phys. 2019 Mar 2. pii: S0360-3016(19)30290-1. doi: 10.1016/j.ijrobp.2019.02.046. [Epub ahead of print] No abstract available.


Kinesin-6 regulates cell-size-dependent spindle elongation velocity to keep mitosis duration constant in fission yeast.

Krüger LK, Sanchez JL, Paoletti A, Tran PT.

Elife. 2019 Feb 26;8. pii: e42182. doi: 10.7554/eLife.42182.


Hereditary Spherocytosis Presenting as Diffuse Bone Marrow Activation and Splenomegaly on PSMA-Targeted 18F-DCFPyL PET/CT.

Gomez E, Tran PT, Pienta KJ, Pomper MG, Gorin MA, Rowe SP.

Clin Nucl Med. 2019 Apr;44(4):e313-e314. doi: 10.1097/RLU.0000000000002489.


Author's view: epithelial plasticity metabolically reprograms normal cells towards a neoplastic-prone state.

Wang H, Tran PT.

Mol Cell Oncol. 2018 Dec 24;6(1):1543485. doi: 10.1080/23723556.2018.1543485. eCollection 2019.


Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1).

Yoon S, Kim SE, Kim JH, Yoon I, Tran PT, Ann J, Kim C, Byun WS, Lee S, Kim S, Lee J, Lee J.

Bioorg Med Chem. 2019 Mar 15;27(6):1099-1109. doi: 10.1016/j.bmc.2019.01.037. Epub 2019 Jan 30.


(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.

Huan LC, Phuong CV, Truc LC, Thanh VN, Pham-The H, Huong LT, Thuan NT, Park EJ, Ji AY, Kang JS, Han SB, Tran PT, Nam NH.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):465-478. doi: 10.1080/14756366.2018.1555536.


Factors affecting quality of life in children and adolescents with hypermobile Ehlers-Danlos syndrome/hypermobility spectrum disorders.

Mu W, Muriello M, Clemens JL, Wang Y, Smith CH, Tran PT, Rowe PC, Francomano CA, Kline AD, Bodurtha J.

Am J Med Genet A. 2019 Apr;179(4):561-569. doi: 10.1002/ajmg.a.61055. Epub 2019 Jan 31.


Individual and Occupational Differences in Perceived Organisational Culture of a Central Hospital in Vietnam.

Nguyen Van H, Nguyen ATH, Nguyen TTH, Nguyen HTT, Bui HTT, Tran PT, Nguyen ALT.

Biomed Res Int. 2018 Dec 24;2018:3759290. doi: 10.1155/2018/3759290. eCollection 2018.


Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1.

Tran PT, Dat NT, Dang NH, Van Cuong P, Lee S, Hwangbo C, Van Minh C, Lee JH.

Phytomedicine. 2019 Mar 1;55:1-8. doi: 10.1016/j.phymed.2018.10.029. Epub 2018 Oct 25.


Degalactotigonin, a Steroidal Glycoside from Solanum nigrum, Induces Apoptosis and Cell Cycle Arrest via Inhibiting the EGFR Signaling Pathways in Pancreatic Cancer Cells.

Tuan Anh HL, Tran PT, Thao DT, Trang DT, Dang NH, Van Cuong P, Kiem PV, Minh CV, Lee JH.

Biomed Res Int. 2018 Dec 16;2018:3120972. doi: 10.1155/2018/3120972. eCollection 2018.


What Is Oligometastatic Prostate Cancer?

Fraser M, Koontz B, Emmenegger U, De Meerleer G, Khoo V, Feng F, Corcoran NM, Hovens CM, Tran PT, Ost P, Boutros PC; GAP6 Consortium.

Eur Urol Focus. 2019 Mar;5(2):159-161. doi: 10.1016/j.euf.2018.12.009. Epub 2019 Jan 12. Review.


A plant intron enhances the performance of an infectious clone in planta.

Tran PT, Fang M, Widyasari K, Kim KH.

J Virol Methods. 2019 Mar;265:26-34. doi: 10.1016/j.jviromet.2018.12.012. Epub 2018 Dec 19.


Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system.

Maxwell R, Luksik AS, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Choi J, Theodros D, Jackson CM, Mathios D, Ye X, Tran PT, Redmond KJ, Brem H, Pardoll DM, Kleinberg LR, Lim M.

Oncoimmunology. 2018 Sep 6;7(12):e1500108. doi: 10.1080/2162402X.2018.1500108. eCollection 2018.


Clinical Development of Novel Drug-Radiotherapy Combinations.

Ahmad SS, Crittenden MR, Tran PT, Kluetz PG, Blumenthal GM, Bulbeck H, Baird RD, Williams KJ, Illidge T, Hahn SM, Lawrence TS, Spears PA, Walker AJ, Sharma RA.

Clin Cancer Res. 2019 Mar 1;25(5):1455-1461. doi: 10.1158/1078-0432.CCR-18-2466. Epub 2018 Nov 29.


Correction to: Anti-inflammatory activity of caffeic acid derivatives isolated from the roots of Salvia miltiorrhiza Bunge.

Choi HG, Tran PT, Lee JH, Min BS, Kim JA.

Arch Pharm Res. 2019 Apr;42(4):378. doi: 10.1007/s12272-018-1090-7.


Local failure is a dominant mode of recurrence in locally advanced and clinical node positive prostate cancer patients treated with combined pelvic IMRT and androgen deprivation therapy.

Hayman J, Hole KH, Seierstad T, Perin J, DeWeese TL, Tran PT, Lilleby W.

Urol Oncol. 2019 Apr;37(4):289.e19-289.e26. doi: 10.1016/j.urolonc.2018.09.016. Epub 2018 Nov 13.


Hybrid TSR⁻PSR Alternate Energy Harvesting Relay Network over Rician Fading Channels: Outage Probability and SER Analysis.

Nguyen TN, Tran Tin P, Ha DH, Voznak M, Tran PT, Tran M, Nguyen TL.

Sensors (Basel). 2018 Nov 9;18(11). pii: E3839. doi: 10.3390/s18113839.


Efficacy of Radium-223 in Bone-metastatic Castration-resistant Prostate Cancer with and Without Homologous Repair Gene Defects.

Isaacsson Velho P, Qazi F, Hassan S, Carducci MA, Denmeade SR, Markowski MC, Thorek DL, DeWeese TL, Song DY, Tran PT, Eisenberger MA, Antonarakis ES.

Eur Urol. 2019 Aug;76(2):170-176. doi: 10.1016/j.eururo.2018.09.040. Epub 2018 Oct 4.


Liquid lipase-catalyzed hydrolysis of gac oil for fatty acid production: Optimization using response surface methodology.

Su CH, Nguyen HC, Nguyen ML, Tran PT, Wang FM, Guan YL.

Biotechnol Prog. 2018 Sep;34(5):1129-1136. doi: 10.1002/btpr.2714. Epub 2018 Oct 3.


Is Androgen Deprivation Therapy "Another Deficient Therapy" for Gleason Score 9-10 Prostate Cancer?

Deek MP, Phillips RM, Haffner M, Tran PT.

Eur Urol. 2019 Jan;75(1):42-43. doi: 10.1016/j.eururo.2018.09.027. Epub 2018 Sep 26. No abstract available.


The influence of individualistic and collectivistic morality on dementia care choices.

Hanssen I, Tran PTM.

Nurs Ethics. 2019 Nov-Dec;26(7-8):2047-2057. doi: 10.1177/0969733018791342. Epub 2018 Sep 10.


Stereotactic ablative radiation therapy for oligometastatic prostate cancer delays time-to-next systemic treatment.

Moyer CL, Phillips R, Deek MP, Radwan N, Ross AE, Antonarakis ES, Reyes D, Wright J, Terezakis SA, Song DY, DeVille C, Walsh PC, DeWeese TL, Carducci M, Schaeffer EM, Pienta KJ, Eisenberger M, Tran PT.

World J Urol. 2018 Sep 6. doi: 10.1007/s00345-018-2477-2. [Epub ahead of print]


Pain and sleep quality in children with non-vascular Ehlers-Danlos syndromes.

Muriello M, Clemens JL, Mu W, Tran PT, Rowe PC, Smith CH, Francomano C, Bodurtha J, Kline AD.

Am J Med Genet A. 2018 Sep;176(9):1858-1864. doi: 10.1002/ajmg.a.40371. Epub 2018 Sep 4.


Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer.

Yochum ZA, Cades J, Wang H, Chatterjee S, Simons BW, O'Brien JP, Khetarpal SK, Lemtiri-Chlieh G, Myers KV, Huang EH, Rudin CM, Tran PT, Burns TF.

Oncogene. 2019 Jan;38(5):656-670. doi: 10.1038/s41388-018-0482-y. Epub 2018 Aug 31.


O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis.

Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya MA, Wang X, Simons BW, Ballew M, Nugent K, Groves J, Williams RD, Shiraishi T, Verdone J, Yildirir G, Henry R, Zhang B, Wong J, Wang KK, Nelkin BD, Pienta KJ, Felsher D, Zachara NE, Tran PT.

J Clin Invest. 2018 Nov 1;128(11):4924-4937. doi: 10.1172/JCI94844. Epub 2018 Sep 24.


N'-[(E)-Arylidene]-2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity.

Huan LC, Truc LC, Phuong CV, Hai PT, Huong LT, Linh NTP, Thuan NT, Park EJ, Choi YJ, Kang JS, Han SB, Nam NH, Tran PT.

Chem Biodivers. 2018 Oct;15(10):e1800322. doi: 10.1002/cbdv.201800322. Epub 2018 Sep 24.


Clinical Outcomes for Patients With Gleason Score 10 Prostate Adenocarcinoma: Results From a Multi-institutional Consortium Study.

Sandler KA, Cook RR, Ciezki JP, Ross AE, Pomerantz MM, Nguyen PL, Shaikh T, Tran PT, Stock RG, Merrick GS, Demanes DJ, Spratt DE, Abu-Isa EI, Wedde TB, Lilleby W, Krauss DJ, Shaw GK, Alam R, Reddy CA, Song DY, Klein EA, Stephenson AJ, Tosoian JJ, Hegde JV, Yoo SM, Fiano R, D'Amico AV, Nickols NG, Aronson WJ, Sadeghi A, Greco SC, Deville C, McNutt T, DeWeese TL, Reiter RE, Said JW, Steinberg ML, Horwitz EM, Kupelian PA, King CR, Kishan AU.

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):883-888. doi: 10.1016/j.ijrobp.2018.03.060. Epub 2018 Apr 5.


ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation.

Vendetti FP, Karukonda P, Clump DA, Teo T, Lalonde R, Nugent K, Ballew M, Kiesel BF, Beumer JH, Sarkar SN, Conrads TP, O'Connor MJ, Ferris RL, Tran PT, Delgoffe GM, Bakkenist CJ.

J Clin Invest. 2018 Aug 31;128(9):3926-3940. doi: 10.1172/JCI96519. Epub 2018 Aug 13.


Data integrity systems for organ contours in radiation therapy planning.

Shah VP, Lakshminarayanan P, Moore J, Tran PT, Quon H, Deville C, McNutt TR.

J Appl Clin Med Phys. 2018 Jul;19(4):58-67. doi: 10.1002/acm2.12353. Epub 2018 Jun 12.


Energy Harvesting over Rician Fading Channel: A Performance Analysis for Half-Duplex Bidirectional Sensor Networks under Hardware Impairments.

Nguyen TN, Quang Minh TH, Tran PT, Vozňák M.

Sensors (Basel). 2018 Jun 1;18(6). pii: E1781. doi: 10.3390/s18061781.

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