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Items: 1 to 50 of 124

1.

Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma.

Harder BG, Blomquist MR, Wang J, Kim AJ, Woodworth GF, Winkles JA, Loftus JC, Tran NL.

Front Oncol. 2018 Oct 23;8:462. doi: 10.3389/fonc.2018.00462. eCollection 2018. Review.

2.

Health system barriers and levers in implementation of the Expanded Program on Immunization (EPI) in Pakistan: an evidence informed situation analysis.

Shaikh BT, Haq ZU, Tran N, Hafeez A.

Public Health Rev. 2018 Sep 17;39:24. doi: 10.1186/s40985-018-0103-x. eCollection 2018. Review.

3.

PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival.

Ding Z, Dhruv H, Kwiatkowska-Piwowarczyk A, Ruggieri R, Kloss J, Symons M, Pirrotte P, Eschbacher JM, Tran NL, Loftus JC.

Neoplasia. 2018 Oct;20(10):1045-1058. doi: 10.1016/j.neo.2018.08.008. Epub 2018 Sep 13.

4.

Role of district health management teams in child health strategies.

Doherty T, Tran N, Sanders D, Dalglish SL, Hipgrave D, Rasanathan K, Sundararaman T, Ved R, Mason E.

BMJ. 2018 Jul 30;362:k2823. doi: 10.1136/bmj.k2823. No abstract available.

5.

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes.

van Tran N, Muller L, Ross RL, Lestini R, Létoquart J, Ulryck N, Limbach PA, de Crécy-Lagard V, Cianférani S, Graille M.

Nucleic Acids Res. 2018 Sep 19;46(16):8483-8499. doi: 10.1093/nar/gky638.

6.

The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.

Hersh DS, Harder BG, Roos A, Peng S, Heath JE, Legesse T, Kim AJ, Woodworth GF, Tran NL, Winkles JA.

Neuro Oncol. 2018 Sep 3;20(10):1321-1330. doi: 10.1093/neuonc/noy063.

PMID:
29897522
7.

Building a Workforce for Future Health Systems: Reflections from Health Policy and Systems Research.

Javadi D, Tran N, Ghaffar A.

Health Serv Res. 2018 Oct;53 Suppl 2:4024-4033. doi: 10.1111/1475-6773.12978. Epub 2018 May 24.

PMID:
29797708
8.

Evaluation of pre-analytical factors affecting plasma DNA analysis.

Markus H, Contente-Cuomo T, Farooq M, Liang WS, Borad MJ, Sivakumar S, Gollins S, Tran NL, Dhruv HD, Berens ME, Bryce A, Sekulic A, Ribas A, Trent JM, LoRusso PM, Murtaza M.

Sci Rep. 2018 May 9;8(1):7375. doi: 10.1038/s41598-018-25810-0.

9.

EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.

Roos A, Dhruv HD, Peng S, Inge LJ, Tuncali S, Pineda M, Millard N, Mayo Z, Eschbacher JM, Loftus JC, Winkles JA, Tran NL.

Mol Cancer Res. 2018 Jul;16(7):1185-1195. doi: 10.1158/1541-7786.MCR-18-0125. Epub 2018 May 3.

PMID:
29724813
10.

Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas.

Hersh DS, Peng S, Dancy JG, Galisteo R, Eschbacher JM, Castellani RJ, Heath JE, Legesse T, Kim AJ, Woodworth GF, Tran NL, Winkles JA.

J Neurooncol. 2018 Jun;138(2):241-250. doi: 10.1007/s11060-018-2799-3. Epub 2018 Feb 16.

11.

Health policy and systems research: towards a better understanding and review of ethical issues.

Luyckx VA, Biller-Andorno N, Saxena A, Tran NT.

BMJ Glob Health. 2017 Jun 10;2(2):e000314. doi: 10.1136/bmjgh-2017-000314. eCollection 2017. Review.

12.

A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion.

Ding Z, Roos A, Kloss J, Dhruv H, Peng S, Pirrotte P, Eschbacher JM, Tran NL, Loftus JC.

Mol Cancer Res. 2018 Feb;16(2):322-332. doi: 10.1158/1541-7786.MCR-17-0454. Epub 2017 Nov 8.

PMID:
29117939
13.

Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma.

Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, Maggiora GM, Peng S, Nasser S, Liang WS, Trent JM, Berens ME, Carpten JD, Craig DW, Prados MD.

Clin Cancer Res. 2018 Jan 15;24(2):295-305. doi: 10.1158/1078-0432.CCR-17-0963. Epub 2017 Oct 26.

PMID:
29074604
14.

Embedding research in health policy and systems in the Americas.

Langlois EV, Nhan TT, Ghaffar A, Reveiz L, Becerra-Posada F.

Rev Panam Salud Publica. 2017 Oct 19;41:e68. No abstract available.

15.

Programme Reporting Standards (PRS) for improving the reporting of sexual, reproductive, maternal, newborn, child and adolescent health programmes.

Kågesten AE, Tunçalp Ö, Portela A, Ali M, Tran N, Gülmezoglu AM.

BMC Med Res Methodol. 2017 Aug 3;17(1):117. doi: 10.1186/s12874-017-0384-7.

16.

Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion.

Roos A, Ding Z, Loftus JC, Tran NL.

Front Oncol. 2017 Jun 16;7:120. doi: 10.3389/fonc.2017.00120. eCollection 2017. Review.

17.

Embedding research to improve program implementation in Latin America and the Caribbean.

Tran N, Langlois EV, Reveiz L, Varallyay I, Elias V, Mancuso A, Becerra-Posada F, Ghaffar A.

Rev Panam Salud Publica. 2017 Jun 8;41:e75.

18.

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples.

Nazarov PV, Muller A, Kaoma T, Nicot N, Maximo C, Birembaut P, Tran NL, Dittmar G, Vallar L.

BMC Genomics. 2017 Jun 6;18(1):443. doi: 10.1186/s12864-017-3819-y.

19.

mTCTScan: a comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers.

Li MJ, Yao H, Huang D, Liu H, Liu Z, Xu H, Qin Y, Prinz J, Xia W, Wang P, Yan B, Tran NL, Kocher JP, Sham PC, Wang J.

Nucleic Acids Res. 2017 Jul 3;45(W1):W215-W221. doi: 10.1093/nar/gkx400.

20.

PCP and SAX-3/Robo Pathways Cooperate to Regulate Convergent Extension-Based Nerve Cord Assembly in C. elegans.

Shah PK, Tanner MR, Kovacevic I, Rankin A, Marshall TE, Noblett N, Tran NN, Roenspies T, Hung J, Chen Z, Slatculescu C, Perkins TJ, Bao Z, Colavita A.

Dev Cell. 2017 Apr 24;41(2):195-203.e3. doi: 10.1016/j.devcel.2017.03.024.

21.

Strengthening health systems through embedded research.

Ghaffar A, Langlois EV, Rasanathan K, Peterson S, Adedokun L, Tran NT.

Bull World Health Organ. 2017 Feb 1;95(2):87. doi: 10.2471/BLT.16.189126. No abstract available.

22.

Alliance for Health Policy and Systems Research: aims, achievements and ambitions.

Ghaffar A, Tran N, Langlois E, Shroff Z, Javadi D.

Public Health Res Pract. 2017 Feb 15;27(1). pii: 2711703. doi: 10.17061/phrp2711703.

23.

IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.

Viladomiu M, Kivolowitz C, Abdulhamid A, Dogan B, Victorio D, Castellanos JG, Woo V, Teng F, Tran NL, Sczesnak A, Chai C, Kim M, Diehl GE, Ajami NJ, Petrosino JF, Zhou XK, Schwartzman S, Mandl LA, Abramowitz M, Jacob V, Bosworth B, Steinlauf A, Scherl EJ, Wu HJ, Simpson KW, Longman RS.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaaf9655. doi: 10.1126/scitranslmed.aaf9655.

24.

Trm112, a Protein Activator of Methyltransferases Modifying Actors of the Eukaryotic Translational Apparatus.

Bourgeois G, Létoquart J, van Tran N, Graille M.

Biomolecules. 2017 Jan 27;7(1). pii: E7. doi: 10.3390/biom7010007. Review.

25.

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.

Roos A, Dhruv HD, Mathews IT, Inge LJ, Tuncali S, Hartman LK, Chow D, Millard N, Yin HH, Kloss J, Loftus JC, Winkles JA, Berens ME, Tran NL.

Oncotarget. 2017 Feb 14;8(7):12234-12246. doi: 10.18632/oncotarget.14685.

26.

Developing the ethics of implementation research in health.

Gopichandran V, Luyckx VA, Biller-Andorno N, Fairchild A, Singh J, Tran N, Saxena A, Launois P, Reis A, Maher D, Vahedi M.

Implement Sci. 2016 Dec 9;11(1):161.

27.

Integrated genomic analysis of survival outliers in glioblastoma.

Peng S, Dhruv H, Armstrong B, Salhia B, Legendre C, Kiefer J, Parks J, Virk S, Sloan AE, Ostrom QT, Barnholtz-Sloan JS, Tran NL, Berens ME.

Neuro Oncol. 2017 Jun 1;19(6):833-844. doi: 10.1093/neuonc/now269.

28.

India's new health systems knowledge platform-making research matter.

Sheikh K, Kumar S, Ved R, Kumar S, Raman VR, Ghaffar A, Tran N, Reddy S, Swaminathan S.

Lancet. 2016 Dec 3;388(10061):2724-2725. doi: 10.1016/S0140-6736(16)32391-1. Epub 2016 Dec 2. No abstract available.

PMID:
27924765
29.

Hydrogen gas sensors from polysilicon nanobelt devices selectively modified with sensing materials.

Tran NA, Pan FM, Sheu JT.

Nanotechnology. 2016 Dec 16;27(50):505604. Epub 2016 Nov 21.

PMID:
27869644
30.

Tumor-targeted nanotherapeutics: overcoming treatment barriers for glioblastoma.

Wadajkar AS, Dancy JG, Hersh DS, Anastasiadis P, Tran NL, Woodworth GF, Winkles JA, Kim AJ.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jul;9(4). doi: 10.1002/wnan.1439. Epub 2016 Nov 4. Review.

31.

Radiogenomics to characterize regional genetic heterogeneity in glioblastoma.

Hu LS, Ning S, Eschbacher JM, Baxter LC, Gaw N, Ranjbar S, Plasencia J, Dueck AC, Peng S, Smith KA, Nakaji P, Karis JP, Quarles CC, Wu T, Loftus JC, Jenkins RB, Sicotte H, Kollmeyer TM, O'Neill BP, Elmquist W, Hoxworth JM, Frakes D, Sarkaria J, Swanson KR, Tran NL, Li J, Mitchell JR.

Neuro Oncol. 2017 Jan;19(1):128-137. doi: 10.1093/neuonc/now135. Epub 2016 Aug 8.

32.

Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma.

Markowitz D, Powell C, Tran NL, Berens ME, Ryken TC, Vanan M, Rosen L, He M, Sun S, Symons M, Al-Abed Y, Ruggieri R.

Mol Cancer Ther. 2016 Aug;15(8):1799-808. doi: 10.1158/1535-7163.MCT-15-0849. Epub 2016 May 20.

33.

Gut Microbiota Drive Autoimmune Arthritis by Promoting Differentiation and Migration of Peyer's Patch T Follicular Helper Cells.

Teng F, Klinger CN, Felix KM, Bradley CP, Wu E, Tran NL, Umesaki Y, Wu HJ.

Immunity. 2016 Apr 19;44(4):875-88. doi: 10.1016/j.immuni.2016.03.013.

34.

Enhancing evidence informed policymaking in complex health systems: lessons from multi-site collaborative approaches.

Langlois EV, Becerril Montekio V, Young T, Song K, Alcalde-Rabanal J, Tran N.

Health Res Policy Syst. 2016 Mar 17;14:20. doi: 10.1186/s12961-016-0089-0.

35.

Reporting guidelines for implementation and operational research.

Hales S, Lesher-Trevino A, Ford N, Maher D, Ramsay A, Tran N.

Bull World Health Organ. 2016 Jan 1;94(1):58-64. doi: 10.2471/BLT.15.167585. Epub 2015 Dec 2.

36.

SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.

Ensign SP, Roos A, Mathews IT, Dhruv HD, Tuncali S, Sarkaria JN, Symons MH, Loftus JC, Berens ME, Tran NL.

Mol Cancer Res. 2016 Mar;14(3):302-12. doi: 10.1158/1541-7786.MCR-15-0183. Epub 2016 Jan 13.

37.

Multi-Parametric MRI and Texture Analysis to Visualize Spatial Histologic Heterogeneity and Tumor Extent in Glioblastoma.

Hu LS, Ning S, Eschbacher JM, Gaw N, Dueck AC, Smith KA, Nakaji P, Plasencia J, Ranjbar S, Price SJ, Tran N, Loftus J, Jenkins R, O'Neill BP, Elmquist W, Baxter LC, Gao F, Frakes D, Karis JP, Zwart C, Swanson KR, Sarkaria J, Wu T, Mitchell JR, Li J.

PLoS One. 2015 Nov 24;10(11):e0141506. doi: 10.1371/journal.pone.0141506. eCollection 2015.

38.

Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway.

Dhruv HD, Roos A, Tomboc PJ, Tuncali S, Chavez A, Mathews I, Berens ME, Loftus JC, Tran NL.

J Neurooncol. 2016 Feb;126(3):397-404. doi: 10.1007/s11060-015-1981-0. Epub 2015 Nov 12.

39.

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.

Salanti A, Clausen TM, Agerbæk MØ, Al Nakouzi N, Dahlbäck M, Oo HZ, Lee S, Gustavsson T, Rich JR, Hedberg BJ, Mao Y, Barington L, Pereira MA, LoBello J, Endo M, Fazli L, Soden J, Wang CK, Sander AF, Dagil R, Thrane S, Holst PJ, Meng L, Favero F, Weiss GJ, Nielsen MA, Freeth J, Nielsen TO, Zaia J, Tran NL, Trent J, Babcook JS, Theander TG, Sorensen PH, Daugaard M.

Cancer Cell. 2015 Oct 12;28(4):500-514. doi: 10.1016/j.ccell.2015.09.003.

40.

Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.

Létoquart J, van Tran N, Caroline V, Aleksandrov A, Lazar N, van Tilbeurgh H, Liger D, Graille M.

Nucleic Acids Res. 2015 Dec 15;43(22):10989-1002. doi: 10.1093/nar/gkv1009. Epub 2015 Oct 4.

41.

A Systematic Review of Reporting Tools Applicable to Sexual and Reproductive Health Programmes: Step 1 in Developing Programme Reporting Standards.

Kågesten A, Tunçalp Ӧ, Ali M, Chandra-Mouli V, Tran N, Gülmezoglu AM.

PLoS One. 2015 Sep 29;10(9):e0138647. doi: 10.1371/journal.pone.0138647. eCollection 2015. Review.

42.

Toward precision medicine in glioblastoma: the promise and the challenges.

Prados MD, Byron SA, Tran NL, Phillips JJ, Molinaro AM, Ligon KL, Wen PY, Kuhn JG, Mellinghoff IK, de Groot JF, Colman H, Cloughesy TF, Chang SM, Ryken TC, Tembe WD, Kiefer JA, Berens ME, Craig DW, Carpten JD, Trent JM.

Neuro Oncol. 2015 Aug;17(8):1051-63. doi: 10.1093/neuonc/nov031. Epub 2015 May 1. Review.

43.

Health policy and systems research: building momentum and community.

Ghaffar A, Tran N, Røttingen JA, Kieny MP.

Bull World Health Organ. 2014 Dec 1;92(12):851. doi: 10.2471/BLT.14.149393. No abstract available.

44.

The role of NGOs in child injury prevention: an organizational assessment of one network of NGOs.

Bachani AM, Tran NT, Agrawal S, Hyder AA.

Health Policy. 2015 Jan;119(1):74-81. doi: 10.1016/j.healthpol.2014.10.010. Epub 2014 Oct 22.

PMID:
25456016
45.

The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator of Src-Driven Cell Invasion.

Cheng E, Whitsett TG, Tran NL, Winkles JA.

Mol Cancer Res. 2015 Mar;13(3):575-83. doi: 10.1158/1541-7786.MCR-14-0411. Epub 2014 Nov 12.

46.

Development of human serine protease-based therapeutics targeting Fn14 and identification of Fn14 as a new target overexpressed in TNBC.

Zhou H, Mohamedali KA, Gonzalez-Angulo AM, Cao Y, Migliorini M, Cheung LH, LoBello J, Lei X, Qi Y, Hittelman WN, Winkles JA, Tran NL, Rosenblum MG.

Mol Cancer Ther. 2014 Nov;13(11):2688-705. doi: 10.1158/1535-7163.MCT-14-0346. Epub 2014 Sep 19.

47.

Goal setting and knowledge generation through health policy and systems research in low- and middle-income countries.

Xue J, Murthy B, Tran NT, Ghaffar A.

Health Res Policy Syst. 2014 Aug 14;12:39. doi: 10.1186/1478-4505-12-39.

48.

An integrated approach to identifying clinically relevant targets in pediatric gliomas.

McEachron TA, Tomboc P, Tran NL.

CNS Oncol. 2013 Jul;2(4):303-6. doi: 10.2217/cns.13.21. No abstract available.

49.

LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress.

Inge LJ, Friel JM, Richer AL, Fowler AJ, Whitsett T, Smith MA, Tran NL, Bremner RM.

Cancer Lett. 2014 Oct 1;352(2):187-95. doi: 10.1016/j.canlet.2014.06.011. Epub 2014 Jul 8.

PMID:
25011082
50.

FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion.

Whitsett TG, Fortin Ensign SP, Dhruv HD, Inge LJ, Kurywchak P, Wolf KK, LoBello J, Kingsley CB, Allen JW, Weiss GJ, Tran NL.

Clin Exp Metastasis. 2014 Aug;31(6):613-23. doi: 10.1007/s10585-014-9653-6. Epub 2014 Apr 8.

PMID:
24710956

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