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Items: 1 to 50 of 88

1.

SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis.

Manikoth Ayyathan D, Koganti P, Marcu-Malina V, Litmanovitch T, Trakhtenbrot L, Emanuelli A, Apel-Sarid L, Blank M.

Oncogene. 2020 Feb 26. doi: 10.1038/s41388-020-1226-3. [Epub ahead of print]

PMID:
32103168
2.

Sustained Response to Imatinib in a Pediatric Patient with Concurrent Myeloproliferative Disease and Lymphoblastic Lymphoma Associated with a CCDC88C-PDGFRB Fusion Gene.

Bielorai B, Leitner M, Goldstein G, Mehrian-Shai R, Trakhtenbrot L, Fisher T, Marcu V, Yalon M, Schiby G, Barel O, Cal N, Golan H, Toren A.

Acta Haematol. 2019;141(2):119-127. doi: 10.1159/000495687. Epub 2019 Feb 6.

PMID:
30726835
3.

Newly diagnosed multiple myeloma patients carrying monoallelic deletion of the whole locus of immunoglobulin heavy chain gene have a better prognosis compared to those with t(4;14) and t(14;16).

Duek A, Trakhtenbrot L, Amariglio N, Benyamini N, Zilbershats I, Ganzel C, Shevetz O, Leiba R, Rozic G, Nagler A, Leiba M.

Genes Chromosomes Cancer. 2019 Aug;58(8):516-520. doi: 10.1002/gcc.22738. Epub 2019 Feb 6.

PMID:
30675954
4.

Is fluorescence in-situ hybridization sufficient in patients with myelodysplastic syndromes and insufficient cytogenetic testing?

Merkel D, Soffer S, Novikov I, Avigdor A, Amariglio N, Nagler A, Trakhtenbrot L.

Leuk Lymphoma. 2019 Mar;60(3):764-771. doi: 10.1080/10428194.2018.1493729. Epub 2018 Sep 6.

PMID:
30187812
5.

The MLL recombinome of acute leukemias in 2017.

Meyer C, Burmeister T, Gröger D, Tsaur G, Fechina L, Renneville A, Sutton R, Venn NC, Emerenciano M, Pombo-de-Oliveira MS, Barbieri Blunck C, Almeida Lopes B, Zuna J, Trka J, Ballerini P, Lapillonne H, De Braekeleer M, Cazzaniga G, Corral Abascal L, van der Velden VHJ, Delabesse E, Park TS, Oh SH, Silva MLM, Lund-Aho T, Juvonen V, Moore AS, Heidenreich O, Vormoor J, Zerkalenkova E, Olshanskaya Y, Bueno C, Menendez P, Teigler-Schlegel A, Zur Stadt U, Lentes J, Göhring G, Kustanovich A, Aleinikova O, Schäfer BW, Kubetzko S, Madsen HO, Gruhn B, Duarte X, Gameiro P, Lippert E, Bidet A, Cayuela JM, Clappier E, Alonso CN, Zwaan CM, van den Heuvel-Eibrink MM, Izraeli S, Trakhtenbrot L, Archer P, Hancock J, Möricke A, Alten J, Schrappe M, Stanulla M, Strehl S, Attarbaschi A, Dworzak M, Haas OA, Panzer-Grümayer R, Sedék L, Szczepański T, Caye A, Suarez L, Cavé H, Marschalek R.

Leukemia. 2018 Feb;32(2):273-284. doi: 10.1038/leu.2017.213. Epub 2017 Jul 13.

6.

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer.

Rabinowicz N, Mangala LS, Brown KR, Checa-Rodriguez C, Castiel A, Moskovich O, Zarfati G, Trakhtenbrot L, Levy-Barda A, Jiang D, Rodriguez-Aguayo C, Pradeep S, van Praag Y, Lopez-Berestein G, David A, Novikov I, Huertas P, Rottapel R, Sood AK, Izraeli S.

Oncotarget. 2017 Apr 18;8(16):27380-27392. doi: 10.18632/oncotarget.16068.

7.

Hairy cell leukemia-variant without typical morphology and with near-tetraploid DNA content.

Azoulay D, Sonkin V, Akria L, Rozano Gorelick A, Trakhtenbrot L, Hershkovitz D, Shaoul E, Rozen S, Dementiev E, Cohen HI, Suriu C, Braester A.

Cytometry B Clin Cytom. 2018 Jan;94(1):169-171. doi: 10.1002/cyto.b.21503. Epub 2017 Feb 6. No abstract available.

8.

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

Biechonski S, Gourevich D, Rall M, Aqaqe N, Yassin M, Zipin-Roitman A, Trakhtenbrot L, Olender L, Raz Y, Jaffa AJ, Grisaru D, Wiesmuller L, Elad D, Milyavsky M.

Int J Cancer. 2017 Feb 15;140(4):864-876. doi: 10.1002/ijc.30497. Epub 2016 Nov 22.

9.

Fluorescence lifetime imaging of DAPI-stained nuclei as a novel diagnostic tool for the detection and classification of B-cell chronic lymphocytic leukemia.

Yahav G, Hirshberg A, Salomon O, Amariglio N, Trakhtenbrot L, Fixler D.

Cytometry A. 2016 Jul;89(7):644-52. doi: 10.1002/cyto.a.22890. Epub 2016 Jun 17.

10.

Translocation t(11;14) in newly diagnosed patients with multiple myeloma: Is it always favorable?

Leiba M, Duek A, Amariglio N, Avigdor A, Benyamini N, Hardan I, Zilbershats I, Ganzel C, Shevetz O, Novikov I, Cohen Y, Ishoev G, Rozic G, Nagler A, Trakhtenbrot L.

Genes Chromosomes Cancer. 2016 Sep;55(9):710-8. doi: 10.1002/gcc.22372. Epub 2016 Jun 24.

PMID:
27152944
11.

Diagnosis of Relapsed Burkitt's Lymphoma in a Urine Sample: an Unusual "FISHing" Expedition.

Sarid N, Kay S, Angel A, Trakhtenbrot L, Amit O, Herishanu Y, Perry C.

Isr Med Assoc J. 2015 Oct;17(10):648-9. No abstract available.

12.

Oral lichen planus patients exhibit consistent chromosomal numerical aberrations: A follow-up analysis.

Yahalom R, Yarom N, Shani T, Amariglio N, Kaplan I, Trakhtenbrot L, Hirshberg A.

Head Neck. 2016 Apr;38 Suppl 1:E741-6. doi: 10.1002/hed.24086. Epub 2015 Jul 30.

PMID:
25900614
13.

Co-existence of clonal expanded autologous and transplacental-acquired maternal T cells in recombination activating gene-deficient severe combined immunodeficiency.

Lev A, Simon AJ, Ben-Ari J, Takagi D, Stauber T, Trakhtenbrot L, Rosenthal E, Rechavi G, Amariglio N, Somech R.

Clin Exp Immunol. 2014 Jun;176(3):380-6. doi: 10.1111/cei.12273.

14.

Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS.

Ben-Shoshan SO, Simon AJ, Jacob-Hirsch J, Shaklai S, Paz-Yaacov N, Amariglio N, Rechavi G, Trakhtenbrot L.

Mol Cytogenet. 2014 Jan 28;7(1):9. doi: 10.1186/1755-8166-7-9.

15.

The MLL recombinome of acute leukemias in 2013.

Meyer C, Hofmann J, Burmeister T, Gröger D, Park TS, Emerenciano M, Pombo de Oliveira M, Renneville A, Villarese P, Macintyre E, Cavé H, Clappier E, Mass-Malo K, Zuna J, Trka J, De Braekeleer E, De Braekeleer M, Oh SH, Tsaur G, Fechina L, van der Velden VH, van Dongen JJ, Delabesse E, Binato R, Silva ML, Kustanovich A, Aleinikova O, Harris MH, Lund-Aho T, Juvonen V, Heidenreich O, Vormoor J, Choi WW, Jarosova M, Kolenova A, Bueno C, Menendez P, Wehner S, Eckert C, Talmant P, Tondeur S, Lippert E, Launay E, Henry C, Ballerini P, Lapillone H, Callanan MB, Cayuela JM, Herbaux C, Cazzaniga G, Kakadiya PM, Bohlander S, Ahlmann M, Choi JR, Gameiro P, Lee DS, Krauter J, Cornillet-Lefebvre P, Te Kronnie G, Schäfer BW, Kubetzko S, Alonso CN, zur Stadt U, Sutton R, Venn NC, Izraeli S, Trakhtenbrot L, Madsen HO, Archer P, Hancock J, Cerveira N, Teixeira MR, Lo Nigro L, Möricke A, Stanulla M, Schrappe M, Sedék L, Szczepański T, Zwaan CM, Coenen EA, van den Heuvel-Eibrink MM, Strehl S, Dworzak M, Panzer-Grümayer R, Dingermann T, Klingebiel T, Marschalek R.

Leukemia. 2013 Nov;27(11):2165-76. doi: 10.1038/leu.2013.135. Epub 2013 Apr 30.

16.

Severe eosinophilia in children: a diagnostic dilemma.

Amshalom A, Lev A, Trakhtenbrot L, Golan H, Weiss B, Amariglio N, Rechavi G, Somech R.

J Pediatr Hematol Oncol. 2013 May;35(4):303-6. doi: 10.1097/MPH.0b013e318290bf0b.

PMID:
23612381
17.

Characterizing T cells in SCID patients presenting with reactive or residual T lymphocytes.

Lev A, Simon AJ, Trakhtenbrot L, Goldstein I, Nagar M, Stepensky P, Rechavi G, Amariglio N, Somech R.

Clin Dev Immunol. 2012;2012:261470. doi: 10.1155/2012/261470. Epub 2012 Nov 20.

18.

Hyperphosphatemia during spontaneous tumor lysis syndrome culminate in severe hypophosphatemia at the time of blast crisis of Phneg CML to acute myelomoncytic leukemia.

Salomon O, Holtzman EJ, Beckerman P, Avivi C, Trakhtenbrot L, Kneller A, Tohami T, Kleinbaum Y, Apter S, Amariglio N, Grossman E, Schiby G.

Exp Hematol Oncol. 2012 Aug 29;1(1):24. doi: 10.1186/2162-3619-1-24.

19.

The increased expression of 14q32 small nucleolar RNA transcripts in promyelocytic leukemia cells is not dependent on PML-RARA fusion gene.

Cohen Y, Hertzog K, Reish O, Mashevich M, Garach-Jehoshua O, Bar-Chaim A, Trakhtenbrot L, Kornberg A.

Blood Cancer J. 2012 Oct 12;2:e92. doi: 10.1038/bcj.2012.39. No abstract available.

20.

Polyploidization of murine mesenchymal cells is associated with suppression of the long noncoding RNA H19 and reduced tumorigenicity.

Shoshani O, Massalha H, Shani N, Kagan S, Ravid O, Madar S, Trakhtenbrot L, Leshkowitz D, Rechavi G, Zipori D.

Cancer Res. 2012 Dec 15;72(24):6403-13. doi: 10.1158/0008-5472.CAN-12-1155. Epub 2012 Oct 9.

21.

Treatment with interferon alpha prior to discontinuation of imatinib in patients with chronic myeloid leukemia.

Hardan I, Stanevsky A, Volchek Y, Tohami T, Amariglio N, Trakhtenbrot L, Koren-Michowitz M, Shimoni A, Nagler A.

Cytokine. 2012 Feb;57(2):290-3. doi: 10.1016/j.cyto.2011.11.018. Epub 2011 Dec 13.

PMID:
22169779
22.

Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy.

Ozery-Flato M, Linhart C, Trakhtenbrot L, Izraeli S, Shamir R.

Genome Biol. 2011 Jun 29;12(6):R61. doi: 10.1186/gb-2011-12-6-r61.

23.

Noninvasive detection of aneuploid cells in laryngeal epithelial precursor lesions.

Shani T, Primov-Fever A, Wolf M, Shalmon B, Amarglio N, Trakhtenbrot L, Hirshberg A.

Cancer Cytopathol. 2011 Aug 25;119(4):235-46. doi: 10.1002/cncy.20157. Epub 2011 May 6.

24.

Therapy-related acute myeloid leukemia with t(2;11)(q37;q23) after treatment for osteosarcoma.

Bielorai B, Meyer C, Trakhtenbrot L, Golan H, Rozner E, Amariglio N, Izraeli S, Marschalek R, Toren A.

Cancer Genet Cytogenet. 2010 Dec;203(2):288-91. doi: 10.1016/j.cancergencyto.2010.08.002.

PMID:
21156246
25.

Post-essential thrombocythemia myelofibrosis and chronic myelomonocytic leukemia can co-exist with complex cytogenetic abnormalities.

Trakhtenbrot L, Tohami T, Schiby G, Kneller A, Rosenthal E, Rosner E, Amariglio N, Salomon O.

Leuk Res. 2010 Nov;34(11):e308-10. doi: 10.1016/j.leukres.2010.06.028. Epub 2010 Jul 23. No abstract available.

PMID:
20655587
26.

Chromosomal numerical aberrations in apparently normal oral mucosa of heavy smokers affected by lung cancer.

Shani T, Onn A, Kabha A, Ben-Dov I, Adam I, Amariglio N, Yahalom R, Rechavi G, Trakhtenbrot L, Hirshberg A.

Oral Oncol. 2010 Feb;46(2):96-9. doi: 10.1016/j.oraloncology.2009.10.010. Epub 2009 Dec 9.

PMID:
20004132
27.

Correlation between losses of IGH or its segments and deletions of 13q14 in t(11;14) (q13;q32) multiple myeloma.

Trakhtenbrot L, Hardan I, Koren-Michowitz M, Oren S, Yshoev G, Rechavi G, Nagler A, Amariglio N.

Genes Chromosomes Cancer. 2010 Jan;49(1):17-27. doi: 10.1002/gcc.20716.

PMID:
19787791
28.

BCR-ABL transcripts are not detected in cord blood or the peripheral blood of the newborn child whose mother developed chronic myeloid leukemia while pregnant.

Salomon O, Tohami T, Trakhtenbrot L, Meirov R, Kneller A, Berkowitz M, Nagler A, Sivan E, Goldman JM, Rechavi G, Amariglio N.

Leuk Res. 2010 Feb;34(2):e78-81. doi: 10.1016/j.leukres.2009.07.010. Epub 2009 Jul 28.

PMID:
19640586
29.

Chromosomal numerical aberrations in oral lichen planus.

Yarom N, Shani T, Amariglio N, Taicher S, Kaplan I, Vered M, Rechavi G, Trakhtenbrot L, Hirshberg A.

J Dent Res. 2009 May;88(5):427-32. doi: 10.1177/0022034509337089.

PMID:
19493885
30.

Involvement of der(12)t(12;21)(p13;q22) and as well as additional rearrangements of chromosome 12 homolog in ETV6/RUNX1-positive acute lymphoblastic leukemia.

Stanchescu R, Betts DR, Rechavi G, Amariglio N, Trakhtenbrot L.

Cancer Genet Cytogenet. 2009 Apr 1;190(1):26-32. doi: 10.1016/j.cancergencyto.2008.12.003.

PMID:
19264230
31.

New insights to the MLL recombinome of acute leukemias.

Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J, Ben Abdelali R, Macintyre E, De Braekeleer E, De Braekeleer M, Delabesse E, de Oliveira MP, Cavé H, Clappier E, van Dongen JJ, Balgobind BV, van den Heuvel-Eibrink MM, Beverloo HB, Panzer-Grümayer R, Teigler-Schlegel A, Harbott J, Kjeldsen E, Schnittger S, Koehl U, Gruhn B, Heidenreich O, Chan LC, Yip SF, Krzywinski M, Eckert C, Möricke A, Schrappe M, Alonso CN, Schäfer BW, Krauter J, Lee DA, Zur Stadt U, Te Kronnie G, Sutton R, Izraeli S, Trakhtenbrot L, Lo Nigro L, Tsaur G, Fechina L, Szczepanski T, Strehl S, Ilencikova D, Molkentin M, Burmeister T, Dingermann T, Klingebiel T, Marschalek R.

Leukemia. 2009 Aug;23(8):1490-9. doi: 10.1038/leu.2009.33. Epub 2009 Mar 5.

PMID:
19262598
32.

Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient.

Amariglio N, Hirshberg A, Scheithauer BW, Cohen Y, Loewenthal R, Trakhtenbrot L, Paz N, Koren-Michowitz M, Waldman D, Leider-Trejo L, Toren A, Constantini S, Rechavi G.

PLoS Med. 2009 Feb 17;6(2):e1000029. doi: 10.1371/journal.pmed.1000029.

33.

Malignant transformation of normal enterocytes following downregulation of Bak expression.

Liberman E, Naumov I, Kazanov D, Dvory-Sobol H, Sagiv E, Birkenfeld S, Deutsch V, Trakhtenbrot L, Moshkowitz M, Arber N.

Digestion. 2008;77(1):48-56. doi: 10.1159/000121411. Epub 2008 Mar 18.

PMID:
18349538
34.

The presence of a single PML-RARA isoform lacking exon 5 in FISH-negative APL samples.

Ashur-Fabian O, Trakhtenbrot L, Dominissini D, Koren-Michowitz M, Nagler A, Rechavi G, Amariglio N.

Leukemia. 2008 Jan;22(1):200-3. Epub 2007 Oct 25. No abstract available.

PMID:
17960172
35.

A new MALDI-TOF-based assay for monitoring JAK2 V617F mutation level in patients undergoing allogeneic stem cell transplantation (allo SCT) for classic myeloproliferative disorders (MPD).

Koren-Michowitz M, Shimoni A, Vivante A, Trakhtenbrot L, Rechavi G, Amariglio N, Loewenthal R, Nagler A, Cohen Y.

Leuk Res. 2008 Mar;32(3):421-7. Epub 2007 Aug 14.

PMID:
17698191
36.

Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis.

Koren-Michowitz M, Hardan I, Berghoff J, Yshoev G, Amariglio N, Rechavi G, Nagler A, Trakhtenbrot L.

Cancer Lett. 2007 Oct 8;255(2):307-14. Epub 2007 Jun 27.

PMID:
17590504
37.

Could rhG-CSF induction of tetraploidy contribute to leukemogenesis in healthy donors?

Kaplinsky C, Trakhtenbrot L, Izraeli S.

Br J Haematol. 2007 Aug;138(4):558. Epub 2007 Jun 21. No abstract available.

PMID:
17590182
38.

The SIL gene is essential for mitotic entry and survival of cancer cells.

Erez A, Castiel A, Trakhtenbrot L, Perelman M, Rosenthal E, Goldstein I, Stettner N, Harmelin A, Eldar-Finkelman H, Campaner S, Kirsch I, Izraeli S.

Cancer Res. 2007 May 1;67(9):4022-7. Epub 2007 Apr 24. Erratum in: Cancer Res. 2007 Jun 15;67(12):5998.

39.

SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia.

Betts DR, Stanchescu R, Niggli FK, Cohen N, Rechavi G, Amariglio N, Trakhtenbrot L.

Leuk Res. 2008 Jan;32(1):39-43. Epub 2007 Apr 6.

PMID:
17418891
40.

Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis - a new method for early detection of suspicious oral lesions.

Hirshberg A, Yarom N, Amariglio N, Yahalom R, Adam I, Stanchescu R, Ben-Dov I, Taicher S, Rechavi G, Trakhtenbrot L.

Cancer Lett. 2007 Aug 18;253(2):282-90. Epub 2007 Mar 26.

PMID:
17386971
41.

Apaf1 in chronic myelogenous leukemia (CML) progression: reduced Apaf1 expression is correlated with a H179R p53 mutation during clinical blast crisis.

Ashur-Fabian O, Adamsky K, Trakhtenbrot L, Cohen Y, Raanani P, Hardan I, Nagler A, Rechavi G, Amariglio N.

Cell Cycle. 2007 Mar 1;6(5):589-94. Epub 2007 Mar 23.

PMID:
17361096
42.

A clonal hypereosinophilic syndrome with specific and effective therapy: a report of two cases.

Ellis MH, Ashur-Fabian O, Trakhtenbrot L, Amariglio N.

Isr Med Assoc J. 2006 Dec;8(12):836-7. No abstract available.

43.

SKY analysis of childhood neural tumors and cell lines demonstrates a susceptibility of aberrant chromosomes to further rearrangements.

Stanchescu R, Betts DR, Yekutieli D, Ambros P, Cohen N, Rechavi G, Amariglio N, Trakhtenbrot L.

Cancer Lett. 2007 May 18;250(1):47-52. Epub 2006 Nov 2.

PMID:
17084022
44.

Comparison of triple helical COMBO-FISH and standard FISH by means of quantitative microscopic image analysis of abl/bcr positions in cell nuclei.

Schwarz-Finsterle J, Stein S, Grossmann C, Schmitt E, Trakhtenbrot L, Rechavi G, Amariglio N, Cremer C, Hausmann M.

J Biochem Biophys Methods. 2007 Apr 10;70(3):397-406. Epub 2006 Sep 19.

PMID:
17069891
45.

P53 in blind subterranean mole rats--loss-of-function versus gain-of-function activities on newly cloned Spalax target genes.

Avivi A, Ashur-Fabian O, Joel A, Trakhtenbrot L, Adamsky K, Goldstein I, Amariglio N, Rechavi G, Nevo E.

Oncogene. 2007 Apr 12;26(17):2507-12. Epub 2006 Oct 16.

PMID:
17043642
46.

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells.

Gal H, Amariglio N, Trakhtenbrot L, Jacob-Hirsh J, Margalit O, Avigdor A, Nagler A, Tavor S, Ein-Dor L, Lapidot T, Domany E, Rechavi G, Givol D.

Leukemia. 2006 Dec;20(12):2147-54. Epub 2006 Oct 12.

PMID:
17039238
47.

COMBO-FISH for focussed fluorescence labelling of gene domains: 3D-analysis of the genome architecture of abl and bcr in human blood cells.

Schwarz-Finsterle J, Stein S, Grossmann C, Schmitt E, Schneider H, Trakhtenbrot L, Rechavi G, Amariglio N, Cremer C, Hausmann M.

Cell Biol Int. 2005 Dec;29(12):1038-46. Epub 2005 Nov 28.

PMID:
16314121
48.

Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression.

Brodsky LI, Jacob-Hirsch J, Avivi A, Trakhtenbrot L, Zeligson S, Amariglio N, Paz A, Korol AB, Band M, Rechavi G, Nevo E.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17047-52. Epub 2005 Nov 14.

49.

Co-existence of multiple subclones in TEL-AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1.

Rothman R, Trakhtenbrot L, Bielorai B, Izraeli S, Ishoev G, Amariglio N, Rechavi G, Toren A.

Br J Haematol. 2005 May;129(4):491-8.

PMID:
15877731
50.

Philadelphia-chromosome-positive T-lymphoblastic leukemia: acute leukemia or chronic myelogenous leukemia blastic crisis.

Raanani P, Trakhtenbrot L, Rechavi G, Rosenthal E, Avigdor A, Brok-Simoni F, Leiba M, Amariglio N, Nagler A, Ben-Bassat I.

Acta Haematol. 2005;113(3):181-9.

PMID:
15870488

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