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Items: 34


Airway host-microbiome interactions in chronic obstructive pulmonary disease.

Wang Z, Maschera B, Lea S, Kolsum U, Michalovich D, Van Horn S, Traini C, Brown JR, Hessel EM, Singh D.

Respir Res. 2019 Jun 6;20(1):113. doi: 10.1186/s12931-019-1085-z.


Nerve sprouting and neurogenic inflammation characterize the neurogenic detrusor overactive bladder of patients no longer responsive to drug therapies.

Traini C, Del Popolo G, Faussone-Pellegrini MS, Guasti D, Catarinicchia S, Vannucchi MG.

J Cell Mol Med. 2019 Jun;23(6):4076-4087. doi: 10.1111/jcmm.14294. Epub 2019 Apr 3.


Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.

Smitheman KN, Severson TM, Rajapurkar SR, McCabe MT, Karpinich N, Foley J, Pappalardi MB, Hughes A, Halsey W, Thomas E, Traini C, Federowicz KE, Laraio J, Mobegi F, Ferron-Brady G, Prinjha RK, Carpenter CL, Kruger RG, Wessels L, Mohammad HP.

Haematologica. 2019 Jun;104(6):1156-1167. doi: 10.3324/haematol.2018.199190. Epub 2018 Dec 4.


Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments.

Yu JW, Bhattacharya S, Yanamandra N, Kilian D, Shi H, Yadavilli S, Katlinskaya Y, Kaczynski H, Conner M, Benson W, Hahn A, Seestaller-Wehr L, Bi M, Vitali NJ, Tsvetkov L, Halsey W, Hughes A, Traini C, Zhou H, Jing J, Lee T, Figueroa DJ, Brett S, Hopson CB, Smothers JF, Hoos A, Srinivasan R.

PLoS One. 2018 Nov 2;13(11):e0206223. doi: 10.1371/journal.pone.0206223. eCollection 2018.


Otilonium Bromide: A Drug with a Complex Mechanism of Action.

Evangelista S, Traini C, Vannucchi MG.

Curr Pharm Des. 2018;24(16):1772-1779. doi: 10.2174/1381612824666180507122935.


The telocytes/myofibroblasts 3-D network forms a stretch receptor in the human bladder mucosa. Is this structure involved in the detrusor overactive diseases?

Vannucchi MG, Traini C.

Ann Anat. 2018 Jul;218:118-123. doi: 10.1016/j.aanat.2018.01.009. Epub 2018 Apr 11. Review.


Gut microbiome differences between metformin- and liraglutide-treated T2DM subjects.

Wang Z, Saha S, Van Horn S, Thomas E, Traini C, Sathe G, Rajpal DK, Brown JR.

Endocrinol Diabetes Metab. 2017 Dec 28;1(1):e00009. doi: 10.1002/edm2.9. eCollection 2018 Jan.


Glucagon-like peptide-2 modulates the nitrergic neurotransmission in strips from the mouse gastric fundus.

Garella R, Idrizaj E, Traini C, Squecco R, Vannucchi MG, Baccari MC.

World J Gastroenterol. 2017 Oct 28;23(40):7211-7220. doi: 10.3748/wjg.v23.i40.7211.


Adaptive changes of telocytes in the urinary bladder of patients affected by neurogenic detrusor overactivity.

Traini C, Fausssone-Pellegrini MS, Guasti D, Del Popolo G, Frizzi J, Serni S, Vannucchi MG.

J Cell Mol Med. 2018 Jan;22(1):195-206. doi: 10.1111/jcmm.13308. Epub 2017 Aug 7.


Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes.

Zhao W, Beers DR, Hooten KG, Sieglaff DH, Zhang A, Kalyana-Sundaram S, Traini CM, Halsey WS, Hughes AM, Sathe GM, Livi GP, Fan GH, Appel SH.

JAMA Neurol. 2017 Jun 1;74(6):677-685. doi: 10.1001/jamaneurol.2017.0357.


Repeated otilonium bromide administration prevents neurotransmitter changes in colon of rats underwent to wrap restraint stress.

Traini C, Evangelista S, Girod V, Faussone-Pellegrini MS, Vannucchi MG.

J Cell Mol Med. 2017 Apr;21(4):735-745. doi: 10.1111/jcmm.13016. Epub 2016 Nov 20.


Key role of scale morphology in flatfishes (Pleuronectiformes) in the ability to keep sand.

Spinner M, Kortmann M, Traini C, Gorb SN.

Sci Rep. 2016 May 20;6:26308. doi: 10.1038/srep26308.


Interstitial cells of Cajal and telocytes in the gut: twins, related or simply neighbor cells?

Vannucchi MG, Traini C.

Biomol Concepts. 2016 May 1;7(2):93-102. doi: 10.1515/bmc-2015-0034. Review.


Changes of excitatory and inhibitory neurotransmitters in the colon of rats underwent to the wrap partial restraint stress.

Traini C, Evangelista S, Girod V, Faussone-Pellegrini MS, Vannucchi MG.

Neurogastroenterol Motil. 2016 Aug;28(8):1172-85. doi: 10.1111/nmo.12816. Epub 2016 Mar 12.


Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase.

Arat S, Spivak A, Van Horn S, Thomas E, Traini C, Sathe G, Livi GP, Ingraham K, Jones L, Aubart K, Holmes DJ, Naderer O, Brown JR.

Antimicrob Agents Chemother. 2015 Feb;59(2):1182-92. doi: 10.1128/AAC.04506-14. Epub 2014 Dec 8.


Telocytes subtypes in human urinary bladder.

Vannucchi MG, Traini C, Guasti D, Del Popolo G, Faussone-Pellegrini MS.

J Cell Mol Med. 2014 Oct;18(10):2000-8. doi: 10.1111/jcmm.12375. Epub 2014 Aug 19.


Inner and outer portions of colonic circular muscle: ultrastructural and immunohistochemical changes in rat chronically treated with otilonium bromide.

Traini C, Faussone-Pellegrini MS, Evangelista S, Mazzaferro K, Cipriani G, Santicioli P, Vannucchi MG.

PLoS One. 2014 Aug 14;9(8):e103237. doi: 10.1371/journal.pone.0103237. eCollection 2014.


γEpithelial Na(+) Channel (γENaC) and the Acid-Sensing Ion Channel 1 (ASIC1) expression in the urothelium of patients with neurogenic detrusor overactivity.

Traini C, Del Popolo G, Lazzeri M, Mazzaferro K, Nelli F, Calosi L, Vannucchi MG.

BJU Int. 2015 Nov;116(5):797-804. doi: 10.1111/bju.12896. Epub 2015 Jun 2.


Telocytes express PDGFRα in the human gastrointestinal tract.

Vannucchi MG, Traini C, Manetti M, Ibba-Manneschi L, Faussone-Pellegrini MS.

J Cell Mol Med. 2013 Sep;17(9):1099-108. doi: 10.1111/jcmm.12134.


The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology.

Grossi C, Rigacci S, Ambrosini S, Ed Dami T, Luccarini I, Traini C, Failli P, Berti A, Casamenti F, Stefani M.

PLoS One. 2013 Aug 8;8(8):e71702. doi: 10.1371/journal.pone.0071702. eCollection 2013.


Chronic treatment with otilonium bromide induces changes in L-type Ca²⁺ channel, tachykinins, and nitric oxide synthase expression in rat colon muscle coat.

Traini C, Cipriani G, Evangelista S, Santicioli P, Faussone-Pellegrini MS, Vannucchi MG.

Neurogastroenterol Motil. 2013 Nov;25(11):e728-39. doi: 10.1111/nmo.12197. Epub 2013 Jul 31.


Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N.

Tatini F, Pugliese AM, Traini C, Niccoli S, Maraula G, Ed Dami T, Mannini B, Scartabelli T, Pedata F, Casamenti F, Chiti F.

Neurobiol Aging. 2013 Sep;34(9):2100-9. doi: 10.1016/j.neurobiolaging.2013.03.020. Epub 2013 Apr 18.


Effects of oxygen and glucose deprivation on synaptic transmission in rat dentate gyrus: role of A2A adenosine receptors.

Maraula G, Traini C, Mello T, Coppi E, Galli A, Pedata F, Pugliese AM.

Neuropharmacology. 2013 Apr;67:511-20. doi: 10.1016/j.neuropharm.2012.12.002. Epub 2012 Dec 19.


Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia.

Muzzi M, Blasi F, Masi A, Coppi E, Traini C, Felici R, Pittelli M, Cavone L, Pugliese AM, Moroni F, Chiarugi A.

J Cereb Blood Flow Metab. 2013 Feb;33(2):183-90. doi: 10.1038/jcbfm.2012.157. Epub 2012 Oct 24.


Relaxin exerts two opposite effects on mechanical activity and nitric oxide synthase expression in the mouse colon.

Baccari MC, Traini C, Garella R, Cipriani G, Vannucchi MG.

Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1142-50. doi: 10.1152/ajpendo.00260.2012. Epub 2012 Aug 28.


Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: a study in APP mutant mice.

Luccarini I, Grossi C, Traini C, Fiorentini A, Ed Dami T, Casamenti F.

Neurosci Lett. 2012 Jan 6;506(1):94-9. doi: 10.1016/j.neulet.2011.10.056. Epub 2011 Oct 26.


P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase 1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro.

Traini C, Pedata F, Cipriani S, Mello T, Galli A, Giovannini MG, Cerbai F, Volpini R, Cristalli G, Pugliese AM.

Eur J Neurosci. 2011 Jun;33(12):2203-15. doi: 10.1111/j.1460-9568.2011.07667.x. Epub 2011 Apr 1.


The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.

Pugliese AM, Traini C, Cipriani S, Gianfriddo M, Mello T, Giovannini MG, Galli A, Pedata F.

Br J Pharmacol. 2009 Jul;157(5):818-30. doi: 10.1111/j.1476-5381.2009.00218.x. Epub 2009 May 5.


Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

Colotta V, Lenzi O, Catarzi D, Varano F, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Traini C, Pedata F, Morizzo E, Moro S.

J Med Chem. 2009 Apr 23;52(8):2407-19. doi: 10.1021/jm8014876.


Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.

Colotta V, Catarzi D, Varano F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Traini C, Pugliese AM, Pedata F, Morizzo E, Moro S.

Bioorg Med Chem. 2008 Jun 1;16(11):6086-102. doi: 10.1016/j.bmc.2008.04.039. Epub 2008 Apr 24.


The role of ATP and adenosine in the brain under normoxic and ischemic conditions.

Pedata F, Melani A, Pugliese AM, Coppi E, Cipriani S, Traini C.

Purinergic Signal. 2007 Sep;3(4):299-310. doi: 10.1007/s11302-007-9085-8. Epub 2007 Oct 11.


Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar.

Spraggs C, McCarthy A, McCarthy L, Hong G, Hughes A, Lin X, Sathe G, Smart D, Traini C, Van Horn S, Warren L, Mosteller M.

Pharmacogenet Genomics. 2007 Dec;17(12):1065-76.


Efflux and target mutations as quinolone resistance mechanisms in clinical isolates of Streptococcus pneumoniae.

Broskey J, Coleman K, Gwynn MN, McCloskey L, Traini C, Voelker L, Warren R.

J Antimicrob Chemother. 2000 Apr;45 Suppl 1:95-9.


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