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Items: 1 to 50 of 377

1.

Peripheral Focused Ultrasound Stimulation (pFUS): New Competitor in Pharmaceutical Markets?

Cotero V, Graf J, Zachs DP, Tracey KJ, Ashe J, Lim HH, Puleo C.

SLAS Technol. 2019 Aug;24(4):448-452. doi: 10.1177/2472630319849383. Epub 2019 Jun 17.

PMID:
31226243
2.

Bioelectronic Medicine: From Preclinical Studies on the Inflammatory Reflex to New Approaches in Disease Diagnosis and Treatment.

Pavlov VA, Chavan SS, Tracey KJ.

Cold Spring Harb Perspect Med. 2019 May 28. pii: a034140. doi: 10.1101/cshperspect.a034140. [Epub ahead of print]

PMID:
31138538
3.

Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation.

Lehner KR, Silverman HA, Addorisio ME, Roy A, Al-Onaizi MA, Levine Y, Olofsson PS, Chavan SS, Gros R, Nathanson NM, Al-Abed Y, Metz CN, Prado VF, Prado MAM, Tracey KJ, Pavlov VA.

Front Immunol. 2019 Apr 2;10:585. doi: 10.3389/fimmu.2019.00585. eCollection 2019.

4.

Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation.

Yang H, Liu H, Zeng Q, Imperato GH, Addorisio ME, Li J, He M, Cheng KF, Al-Abed Y, Harris HE, Chavan SS, Andersson U, Tracey KJ.

Mol Med. 2019 Apr 11;25(1):13. doi: 10.1186/s10020-019-0081-6.

5.

Therapeutic Targeting of High-Mobility Group Box-1 in Pulmonary Arterial Hypertension.

Goldenberg NM, Hu Y, Hu X, Volchuk A, Zhao YD, Kucherenko MM, Knosalla C, de Perrot M, Tracey KJ, Al-Abed Y, Steinberg BE, Kuebler WM.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1566-1569. doi: 10.1164/rccm.201808-1597LE. No abstract available.

PMID:
30939030
6.

Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation.

Cotero V, Fan Y, Tsaava T, Kressel AM, Hancu I, Fitzgerald P, Wallace K, Kaanumalle S, Graf J, Rigby W, Kao TJ, Roberts J, Bhushan C, Joel S, Coleman TR, Zanos S, Tracey KJ, Ashe J, Chavan SS, Puleo C.

Nat Commun. 2019 Mar 12;10(1):952. doi: 10.1038/s41467-019-08750-9.

7.

Choline acetyltransferase-expressing T cells are required to control chronic viral infection.

Cox MA, Duncan GS, Lin GHY, Steinberg BE, Yu LX, Brenner D, Buckler LN, Elia AJ, Wakeham AC, Nieman B, Dominguez-Brauer C, Elford AR, Gill KT, Kubli SP, Haight J, Berger T, Ohashi PS, Tracey KJ, Olofsson PS, Mak TW.

Science. 2019 Feb 8;363(6427):639-644. doi: 10.1126/science.aau9072.

PMID:
30733420
8.

Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis.

Chen W, Zhu S, Wang Y, Li J, Qiang X, Zhao X, Yang H, D'Angelo J, Becker L, Wang P, Tracey KJ, Wang H.

Sci Rep. 2019 Jan 17;9(1):160. doi: 10.1038/s41598-018-37232-z.

9.

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.

Yang H, Wang H, Levine YA, Gunasekaran MK, Wang Y, Addorisio M, Zhu S, Li W, Li J, de Kleijn DP, Olofsson PS, Warren HS, He M, Al-Abed Y, Roth J, Antoine DJ, Chavan SS, Andersson U, Tracey KJ.

JCI Insight. 2018 Dec 20;3(24). pii: 126617. doi: 10.1172/jci.insight.126617. No abstract available.

10.

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.

Yang H, Wang H, Levine YA, Gunasekaran MK, Wang Y, Addorisio M, Zhu S, Li W, Li J, de Kleijn DP, Olofsson PS, Warren HS, He M, Al-Abed Y, Roth J, Antoine DJ, Chavan SS, Andersson U, Tracey KJ.

JCI Insight. 2018 Dec 20;3(24). pii: 126616. doi: 10.1172/jci.insight.126616. No abstract available.

11.

Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex.

Tarnawski L, Reardon C, Caravaca AS, Rosas-Ballina M, Tusche MW, Drake AR, Hudson LK, Hanes WM, Li JH, Parrish WR, Ojamaa K, Al-Abed Y, Faltys M, Pavlov VA, Andersson U, Chavan SS, Levine YA, Mak TW, Tracey KJ, Olofsson PS.

Front Immunol. 2018 Nov 27;9:2648. doi: 10.3389/fimmu.2018.02648. eCollection 2018.

12.

Aerobic Exercise Training and Inducible Inflammation: Results of a Randomized Controlled Trial in Healthy, Young Adults.

Sloan RP, Shapiro PA, McKinley PS, Bartels M, Shimbo D, Lauriola V, Karmally W, Pavlicova M, Choi CJ, Choo TH, Scodes JM, Flood P, Tracey KJ.

J Am Heart Assoc. 2018 Sep 4;7(17):e010201. doi: 10.1161/JAHA.118.010201.

13.

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.

Deng M, Tang Y, Li W, Wang X, Zhang R, Zhang X, Zhao X, Liu J, Tang C, Liu Z, Huang Y, Peng H, Xiao L, Tang D, Scott MJ, Wang Q, Liu J, Xiao X, Watkins S, Li J, Yang H, Wang H, Chen F, Tracey KJ, Billiar TR, Lu B.

Immunity. 2018 Oct 16;49(4):740-753.e7. doi: 10.1016/j.immuni.2018.08.016. Epub 2018 Oct 9.

PMID:
30314759
14.

High mobility group box-1 induces pro-inflammatory signaling in human nucleus pulposus cells via toll-like receptor 4-dependent pathway.

Shah BS, Burt KG, Jacobsen T, Fernandes TD, Alipui DO, Weber KT, Levine M, Chavan SS, Yang H, Tracey KJ, Chahine NO.

J Orthop Res. 2019 Jan;37(1):220-231. doi: 10.1002/jor.24154. Epub 2018 Oct 29.

PMID:
30273982
15.

Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity.

Li S, Liang F, Kwan K, Tang Y, Wang X, Tang Y, Li J, Yang H, Chavan SS, Wang H, Andersson U, Lu B, Tracey KJ.

Mol Med. 2018 Mar 15;24(1):8. doi: 10.1186/s10020-018-0006-9.

16.

Correction to: Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance.

He M, Bianchi ME, Coleman TR, Tracey KJ, Al-Abed Y.

Mol Med. 2018 Jun 13;24(1):31. doi: 10.1186/s10020-018-0030-9.

17.

Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance.

He M, Bianchi ME, Coleman TR, Tracey KJ, Al-Abed Y.

Mol Med. 2018 May 10;24(1):21. doi: 10.1186/s10020-018-0023-8. Erratum in: Mol Med. 2018 Jun 13;24(1):31.

18.

Neurons Are the Inflammatory Problem.

Tracey KJ.

Cell. 2018 May 17;173(5):1066-1068. doi: 10.1016/j.cell.2018.05.005.

19.

Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons.

Gunasekaran M, Chatterjee PK, Shih A, Imperato GH, Addorisio M, Kumar G, Lee A, Graf JF, Meyer D, Marino M, Puleo C, Ashe J, Cox MA, Mak TW, Bouton C, Sherry B, Diamond B, Andersson U, Coleman TR, Metz CN, Tracey KJ, Chavan SS.

Front Immunol. 2018 Apr 16;9:638. doi: 10.3389/fimmu.2018.00638. eCollection 2018.

20.

Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity.

Zanos TP, Silverman HA, Levy T, Tsaava T, Battinelli E, Lorraine PW, Ashe JM, Chavan SS, Tracey KJ, Bouton CE.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4843-E4852. doi: 10.1073/pnas.1719083115. Epub 2018 May 7.

21.

Molecular and Functional Neuroscience in Immunity.

Pavlov VA, Chavan SS, Tracey KJ.

Annu Rev Immunol. 2018 Apr 26;36:783-812. doi: 10.1146/annurev-immunol-042617-053158. Review.

22.

Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors.

Zaghloul N, Addorisio ME, Silverman HA, Patel HL, Valdés-Ferrer SI, Ayasolla KR, Lehner KR, Olofsson PS, Nasim M, Metz CN, Wang P, Ahmed M, Chavan SS, Diamond B, Tracey KJ, Pavlov VA.

Front Immunol. 2017 Dec 15;8:1673. doi: 10.3389/fimmu.2017.01673. eCollection 2017.

23.

Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases.

Li W, Bao G, Chen W, Qiang X, Zhu S, Wang S, He M, Ma G, Ochani M, Al-Abed Y, Yang H, Tracey KJ, Wang P, D'Angelo J, Wang H.

Sci Rep. 2018 Jan 9;8(1):166. doi: 10.1038/s41598-017-18452-1.

24.

New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.

Qiang X, Liotta AS, Shiloach J, Gutierrez JC, Wang H, Ochani M, Ochani K, Yang H, Rabin A, LeRoith D, Lesniak MA, Böhm M, Maaser C, Kannengiesser K, Donowitz M, Rabizadeh S, Czura CJ, Tracey KJ, Westlake M, Zarfeshani A, Mehdi SF, Danoff A, Ge X, Sanyal S, Schwartz GJ, Roth J.

NPJ Biofilms Microbiomes. 2017 Nov 13;3:31. doi: 10.1038/s41522-017-0039-9. eCollection 2017.

25.

Targeting neural reflex circuits in immunity to treat kidney disease.

Okusa MD, Rosin DL, Tracey KJ.

Nat Rev Nephrol. 2017 Nov;13(11):669-680. doi: 10.1038/nrneph.2017.132. Epub 2017 Oct 3. Review.

26.

Galantamine alleviates inflammation and insulin resistance in patients with metabolic syndrome in a randomized trial.

Consolim-Colombo FM, Sangaleti CT, Costa FO, Morais TL, Lopes HF, Motta JM, Irigoyen MC, Bortoloto LA, Rochitte CE, Harris YT, Satapathy SK, Olofsson PS, Akerman M, Chavan SS, MacKay M, Barnaby DP, Lesser ML, Roth J, Tracey KJ, Pavlov VA.

JCI Insight. 2017 Jul 20;2(14). pii: 93340. doi: 10.1172/jci.insight.93340. eCollection 2017 Jul 20.

27.

Mechanisms and Therapeutic Relevance of Neuro-immune Communication.

Chavan SS, Pavlov VA, Tracey KJ.

Immunity. 2017 Jun 20;46(6):927-942. doi: 10.1016/j.immuni.2017.06.008. Review.

28.

A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve.

Caravaca AS, Tsaava T, Goldman L, Silverman H, Riggott G, Chavan SS, Bouton C, Tracey KJ, Desimone R, Boyden ES, Sohal HS, Olofsson PS.

J Neural Eng. 2017 Dec;14(6):066005. doi: 10.1088/1741-2552/aa7a42.

29.

Bioelectronic medicine: technology targeting molecular mechanisms for therapy.

Olofsson PS, Tracey KJ.

J Intern Med. 2017 Jul;282(1):3-4. doi: 10.1111/joim.12624. No abstract available.

30.

The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation.

Yang H, Wang H, Wang Y, Addorisio M, Li J, Postiglione MJ, Chavan SS, Al-Abed Y, Antoine DJ, Andersson U, Tracey KJ.

J Intern Med. 2017 Jul;282(1):76-93. doi: 10.1111/joim.12619. Epub 2017 May 31.

31.

Essential Neuroscience in Immunology.

Chavan SS, Tracey KJ.

J Immunol. 2017 May 1;198(9):3389-3397. doi: 10.4049/jimmunol.1601613. Review.

32.

Neural regulation of immunity: molecular mechanisms and clinical translation.

Pavlov VA, Tracey KJ.

Nat Neurosci. 2017 Feb;20(2):156-166. doi: 10.1038/nn.4477. Epub 2017 Jan 16. Review.

PMID:
28092663
33.

High-Density Lipoprotein (HDL) Counter-Regulates Serum Amyloid A (SAA)-Induced sPLA2-IIE and sPLA2-V Expression in Macrophages.

Zhu S, Wang Y, Chen W, Li W, Wang A, Wong S, Bao G, Li J, Yang H, Tracey KJ, D'Angelo J, Wang H.

PLoS One. 2016 Nov 29;11(11):e0167468. doi: 10.1371/journal.pone.0167468. eCollection 2016.

34.

Obesity paradox, obesity orthodox, and the metabolic syndrome: An approach to unity.

Roth J, Sahota N, Patel P, Mehdi SF, Wiese MM, Mahboob HB, Bravo M, Eden DJ, Bashir MA, Kumar A, Alsaati F, Kurland IJ, Brima W, Danoff A, Szulc AL, Pavlov VA, Tracey KJ, Yang H.

Mol Med. 2017 Feb;22:873-885. doi: 10.2119/molmed.2016.00211. Epub 2016 Nov 16.

35.

C1q and HMGB1 reciprocally regulate human macrophage polarization.

Son M, Porat A, He M, Suurmond J, Santiago-Schwarz F, Andersson U, Coleman TR, Volpe BT, Tracey KJ, Al-Abed Y, Diamond B.

Blood. 2016 Nov 3;128(18):2218-2228. Epub 2016 Sep 28.

36.

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.

Lundbäck P, Lea JD, Sowinska A, Ottosson L, Fürst CM, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, Andersson U, Antoine DJ, Erlandsson Harris H.

Hepatology. 2016 Nov;64(5):1699-1710. doi: 10.1002/hep.28736. Epub 2016 Sep 1.

37.

A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis.

Kang R, Zeng L, Xie Y, Yan Z, Zhou B, Cao L, Klionsky DJ, Tracey KJ, Li J, Wang H, Billiar TR, Jiang J, Tang D.

Autophagy. 2016 Dec;12(12):2374-2385. Epub 2016 Oct 18.

38.

Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.

Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Liu SF, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, Pavlov VA, Broliden K, Andersson U, Diamond B, Miller EJ, Arner A, Gregersen PK, Backx PH, Mak TW, Tracey KJ.

Nat Biotechnol. 2016 Oct;34(10):1066-1071. doi: 10.1038/nbt.3663. Epub 2016 Sep 12.

39.

Efficacy of night-time compression for breast cancer related lymphedema (LYNC): protocol for a multi-centre, randomized controlled efficacy trial.

McNeely ML, Campbell KL, Webster M, Kuusk U, Tracey K, Mackey J.

BMC Cancer. 2016 Aug 4;16:601. doi: 10.1186/s12885-016-2648-8.

40.

Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.

Koopman FA, Chavan SS, Miljko S, Grazio S, Sokolovic S, Schuurman PR, Mehta AD, Levine YA, Faltys M, Zitnik R, Tracey KJ, Tak PP.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8284-9. doi: 10.1073/pnas.1605635113. Epub 2016 Jul 5.

41.

Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice.

Hudson LK, Dancho ME, Li J, Bruchfeld JB, Ragab AA, He MM, Bragg M, Lenaghan D, Quinn MD, Fritz JR, Tanzi MV, Silverman HA, Hanes WM, Levine YA, Pavlov VA, Olofsson PS, Roth J, Al-Abed Y, Andersson U, Tracey KJ, Chavan SS.

Mol Med. 2016 Oct;22:585-596. doi: 10.2119/molmed.2016.00082. Epub 2016 Jun 10.

42.

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.

Yang H, Wang H, Levine YA, Gunasekaran MK, Wang Y, Addorisio M, Zhu S, Li W, Li J, de Kleijn DP, Olofsson PS, Warren HS, He M, Al-Abed Y, Roth J, Antoine DJ, Chavan SS, Andersson U, Tracey KJ.

JCI Insight. 2016;1(7). pii: 85375. doi: 10.1172/jci.insight.85375. Epub 2016 May 19. Erratum in: JCI Insight. 2018 Dec 20;3(24):.

43.

In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin.

Santoro M, Maetzler W, Stathakos P, Martin HL, Hobert MA, Rattay TW, Gasser T, Forrester JV, Berg D, Tracey KJ, Riedel G, Teismann P.

Neurobiol Dis. 2016 Jul;91:59-68. doi: 10.1016/j.nbd.2016.02.018. Epub 2016 Feb 24.

44.

Reflexes in Immunity.

Tracey KJ.

Cell. 2016 Jan 28;164(3):343-4. doi: 10.1016/j.cell.2016.01.018.

45.

Novel strategies for targeting innate immune responses to influenza.

Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, Blanco JC, Vogel SN.

Mucosal Immunol. 2016 Sep;9(5):1173-82. doi: 10.1038/mi.2015.141. Epub 2016 Jan 27.

46.

HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors.

Valdés-Ferrer SI, Papoin J, Dancho ME, Olofsson PS, Li J, Lipton JM, Avancena P, Yang H, Zou YR, Chavan SS, Volpe BT, Gardenghi S, Rivella S, Diamond B, Andersson U, Steinberg BM, Blanc L, Tracey KJ.

Mol Med. 2016 May;21(1):951-958. doi: 10.2119/molmed.2015.00243. Epub 2015 Dec 29.

47.

Cytokine-specific Neurograms in the Sensory Vagus Nerve.

Steinberg BE, Silverman HA, Robbiati S, Gunasekaran MK, Tsaava T, Battinelli E, Stiegler A, Bouton CE, Chavan SS, Tracey KJ, Huerta PT.

Bioelectron Med. 2016;3:7-17.

48.

Regulation of Posttranslational Modifications of HMGB1 During Immune Responses.

Tang Y, Zhao X, Antoine D, Xiao X, Wang H, Andersson U, Billiar TR, Tracey KJ, Lu B.

Antioxid Redox Signal. 2016 Apr 20;24(12):620-34. doi: 10.1089/ars.2015.6409. Epub 2016 Feb 5. Review.

49.

HMGB1-Driven Inflammation and Intimal Hyperplasia After Arterial Injury Involves Cell-Specific Actions Mediated by TLR4.

Cai J, Yuan H, Wang Q, Yang H, Al-Abed Y, Hua Z, Wang J, Chen D, Wu J, Lu B, Pribis JP, Jiang W, Yang K, Hackam DJ, Tracey KJ, Billiar TR, Chen AF.

Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2579-93. doi: 10.1161/ATVBAHA.115.305789. Epub 2015 Oct 29.

50.

Neural circuitry and immunity.

Pavlov VA, Tracey KJ.

Immunol Res. 2015 Dec;63(1-3):38-57. doi: 10.1007/s12026-015-8718-1. Review.

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