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Items: 1 to 50 of 69

1.

Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease.

Vilariño-Güell C, Zimprich A, Martinelli-Boneschi F, Herculano B, Wang Z, Matesanz F, Urcelay E, Vandenbroeck K, Leyva L, Gris D, Massaad C, Quandt JA, Traboulsee AL, Encarnacion M, Bernales CQ, Follett J, Yee IM, Criscuoli MG, Deutschländer A, Reinthaler EM, Zrzavy T, Mascia E, Zauli A, Esposito F, Alcina A, Izquierdo G, Espino-Paisán L, Mena J, Antigüedad A, Urbaneja-Romero P, Ortega-Pinazo J, Song W, Sadovnick AD.

PLoS Genet. 2019 Jun 6;15(6):e1008180. doi: 10.1371/journal.pgen.1008180. eCollection 2019 Jun.

2.

Longitudinal advanced MRI case report of white matter radiation necrosis.

Wiggermann V, Lapointe E, Litvin L, Graf C, Hernández-Torres E, McKenzie M, Vavasour IM, Laule C, MacMillan EL, Li DKB, Kolind SH, Rauscher A, Traboulsee AL.

Ann Clin Transl Neurol. 2018 Dec 10;6(2):379-385. doi: 10.1002/acn3.704. eCollection 2019 Feb.

3.

Effect of different doses of gadolinium contrast agent on clinical outcomes in MS.

Ackermans N, Taylor C, Tam R, Carruthers R, Kolind S, Kang H, Freedman MS, Li DK, Traboulsee AL.

Mult Scler J Exp Transl Clin. 2019 Feb 16;5(1):2055217318823796. doi: 10.1177/2055217318823796. eCollection 2019 Jan-Mar.

4.

Advanced imaging findings in progressive solitary sclerosis: a single lesion or a global disease?

Lee LE, Chan JK, Nevill E, Soares A, Vavasour IM, MacMillan EL, Garren H, Clayton D, Keegan BM, Tam R, Traboulsee AL, Kolind SH, Carruthers RL.

Mult Scler J Exp Transl Clin. 2019 Jan 16;5(1):2055217318824612. doi: 10.1177/2055217318824612. eCollection 2019 Jan-Mar.

5.

Case of alemtuzumab-related alopecia areata management in MS.

Chan JK, Traboulsee AL, Sayao AL.

Neurol Neuroimmunol Neuroinflamm. 2018 Oct 19;6(1):e516. doi: 10.1212/NXI.0000000000000516. eCollection 2019 Jan. No abstract available.

6.

Perspectives of Patients with Multiple Sclerosis on Drug Treatment: A Qualitative Study.

Lynd LD, Henrich NJ, Hategeka C, Marra CA, Mittmann N, Evans C, Traboulsee AL.

Int J MS Care. 2018 Nov-Dec;20(6):269-277. doi: 10.7224/1537-2073.2017-109.

7.

Inter-Vendor Reproducibility of Myelin Water Imaging Using a 3D Gradient and Spin Echo Sequence.

Lee LE, Ljungberg E, Shin D, Figley CR, Vavasour IM, Rauscher A, Cohen-Adad J, Li DKB, Traboulsee AL, MacKay AL, Lee J, Kolind SH.

Front Neurosci. 2018 Nov 21;12:854. doi: 10.3389/fnins.2018.00854. eCollection 2018.

8.

Goodpasture's Syndrome Following Alemtuzumab Therapy in Multiple Sclerosis.

Lapointe E, Moghaddam B, Barclay K, Traboulsee AL, Neufeld P.

Can J Neurol Sci. 2018 Nov;45(6):712-714. doi: 10.1017/cjn.2018.325. Epub 2018 Oct 2. No abstract available.

PMID:
30277178
9.

Safety and efficacy of venoplasty in MS: A randomized, double-blind, sham-controlled phase II trial.

Traboulsee AL, Machan L, Girard JM, Raymond J, Vosoughi R, Hardy BW, Emond F, Gariepy JL, Bone JN, Siskin G, Klass D, Isserow S, Illes J, Sadovnick AD, Li DK.

Neurology. 2018 Oct 30;91(18):e1660-e1668. doi: 10.1212/WNL.0000000000006423. Epub 2018 Sep 28.

10.

Predictive validity of NEDA in the 16- and 21-year follow-up from the pivotal trial of interferon beta-1b.

Goodin DS, Reder AT, Traboulsee AL, Li DK, Langdon D, Cutter G, Cook S, O'Donnell T, Kremenchutzky M, Oger J, Koelbach R, Pohl C, Wicklein EM; IFNB Multiple Sclerosis Study Group and the 16- and 21-Year LTF Investigators.

Mult Scler. 2019 May;25(6):837-847. doi: 10.1177/1352458518773511. Epub 2018 May 15.

PMID:
29761737
11.

What Have We Learned from Perfusion MRI in Multiple Sclerosis?

Lapointe E, Li DKB, Traboulsee AL, Rauscher A.

AJNR Am J Neuroradiol. 2018 Jun;39(6):994-1000. doi: 10.3174/ajnr.A5504. Epub 2018 Jan 4. Review.

12.

Paraneoplastic Neuromyelitis Optica Spectrum Disorder: A single center cohort description with two cases of histological validation.

Beauchemin P, Iorio R, Traboulsee AL, Field T, Tinker AV, Carruthers RL.

Mult Scler Relat Disord. 2018 Feb;20:37-42. doi: 10.1016/j.msard.2017.12.012. Epub 2017 Dec 23.

PMID:
29291482
13.

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.

Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, Correale J, Fazekas F, Filippi M, Freedman MS, Fujihara K, Galetta SL, Hartung HP, Kappos L, Lublin FD, Marrie RA, Miller AE, Miller DH, Montalban X, Mowry EM, Sorensen PS, Tintoré M, Traboulsee AL, Trojano M, Uitdehaag BMJ, Vukusic S, Waubant E, Weinshenker BG, Reingold SC, Cohen JA.

Lancet Neurol. 2018 Feb;17(2):162-173. doi: 10.1016/S1474-4422(17)30470-2. Epub 2017 Dec 21. Review.

PMID:
29275977
14.

Analysis of NOD-like receptor NLRP1 in multiple sclerosis families.

Bernales CQ, Encarnacion M, Criscuoli MG, Yee IM, Traboulsee AL, Sadovnick AD, Vilariño-Güell C.

Immunogenetics. 2018 Mar;70(3):205-207. doi: 10.1007/s00251-017-1034-2. Epub 2017 Oct 7.

PMID:
28988323
15.

Characterization of brain tumours with spin-spin relaxation: pilot case study reveals unique T 2 distribution profiles of glioblastoma, oligodendroglioma and meningioma.

Laule C, Bjarnason TA, Vavasour IM, Traboulsee AL, Wayne Moore GR, Li DKB, MacKay AL.

J Neurol. 2017 Nov;264(11):2205-2214. doi: 10.1007/s00415-017-8609-6. Epub 2017 Sep 11.

PMID:
28894952
16.

Global loss of myelin water over 5 years in multiple sclerosis normal-appearing white matter.

Vavasour IM, Huijskens SC, Li DK, Traboulsee AL, Mädler B, Kolind SH, Rauscher A, Moore GW, MacKay AL, Laule C.

Mult Scler. 2018 Oct;24(12):1557-1568. doi: 10.1177/1352458517723717. Epub 2017 Aug 7.

PMID:
28782447
17.

Cervical cord myelin water imaging shows degenerative changes over one year in multiple sclerosis but not neuromyelitis optica spectrum disorder.

Combes AJE, Matthews L, Lee JS, Li DKB, Carruthers R, Traboulsee AL, Barker GJ, Palace J, Kolind S.

Neuroimage Clin. 2017 Jun 16;16:17-22. doi: 10.1016/j.nicl.2017.06.019. eCollection 2017.

18.

Prognostic factors for long-term outcomes in relapsing-remitting multiple sclerosis.

Traboulsee AL, Cornelisseª P, Sandberg-Wollheim M, Uitdehaag BM, Kappos L, Jongen PJ, Constantinescu CS, di Cantogno EV, Li DK.

Mult Scler J Exp Transl Clin. 2016 Sep 6;2:2055217316666406. doi: 10.1177/2055217316666406. eCollection 2016 Jan-Dec.

19.

Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis.

Metz LM, Li DKB, Traboulsee AL, Duquette P, Eliasziw M, Cerchiaro G, Greenfield J, Riddehough A, Yeung M, Kremenchutzky M, Vorobeychik G, Freedman MS, Bhan V, Blevins G, Marriott JJ, Grand'Maison F, Lee L, Thibault M, Hill MD, Yong VW; Minocycline in MS Study Team.

N Engl J Med. 2017 Jun 1;376(22):2122-2133. doi: 10.1056/NEJMoa1608889.

20.

Genetic modifiers of multiple sclerosis progression, severity and onset.

Sadovnick AD, Traboulsee AL, Zhao Y, Bernales CQ, Encarnacion M, Ross JP, Yee IM, Criscuoli MG, Vilariño-Güell C.

Clin Immunol. 2017 Jul;180:100-105. doi: 10.1016/j.clim.2017.05.009. Epub 2017 May 10.

PMID:
28501589
21.

Timing of high-efficacy therapy in relapsing-remitting multiple sclerosis: A systematic review.

Merkel B, Butzkueven H, Traboulsee AL, Havrdova E, Kalincik T.

Autoimmun Rev. 2017 Jun;16(6):658-665. doi: 10.1016/j.autrev.2017.04.010. Epub 2017 Apr 17. Review.

22.

Common genetic etiology between "multiple sclerosis-like" single-gene disorders and familial multiple sclerosis.

Traboulsee AL, Sadovnick AD, Encarnacion M, Bernales CQ, Yee IM, Criscuoli MG, Vilariño-Güell C.

Hum Genet. 2017 Jun;136(6):705-714. doi: 10.1007/s00439-017-1784-9. Epub 2017 Mar 23.

PMID:
28337550
23.

Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.

Sadovnick AD, Gu BJ, Traboulsee AL, Bernales CQ, Encarnacion M, Yee IM, Criscuoli MG, Huang X, Ou A, Milligan CJ, Petrou S, Wiley JS, Vilariño-Güell C.

Hum Mutat. 2017 Jun;38(6):736-744. doi: 10.1002/humu.23218. Epub 2017 Apr 13.

24.

Patient-Reported Benefits of Extracranial Venous Therapy: British Columbia CCSVI Registry.

Sadovnick AD, Yee IM, Attwell-Pope K, Keyes G, Kipp L, Traboulsee AL.

Can J Neurol Sci. 2017 May;44(3):246-254. doi: 10.1017/cjn.2017.27. Epub 2017 Mar 8.

PMID:
28270250
25.

Prevalence of Extracranial Venous Narrowing on Magnetic Resonance Venography Is Similar in People With Multiple Sclerosis, Their Siblings, and Unrelated Healthy Controls: A Blinded, Case-Control Study.

Martin N, Traboulsee AL, Machan L, Klass D, Ellchuk T, Zhao Y, Knox KB, Kopriva D, Lala S, Nickel D, Otani R, Perera WR, Rauscher A, Sadovnick AD, Szkup P, Li DK.

Can Assoc Radiol J. 2017 May;68(2):202-209. doi: 10.1016/j.carj.2016.07.002. Epub 2016 Nov 22.

PMID:
27887935
26.

Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Oct 19;92(2):555. doi: 10.1016/j.neuron.2016.09.028. No abstract available.

27.

Case-Control Studies Are Not Familial Studies.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Oct 19;92(2):339-341. doi: 10.1016/j.neuron.2016.09.053.

28.

Editorial Note to:Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Oct 19;92(2):331-332. doi: 10.1016/j.neuron.2016.10.008. No abstract available.

29.
30.

Quantifying visual pathway axonal and myelin loss in multiple sclerosis and neuromyelitis optica.

Manogaran P, Vavasour IM, Lange AP, Zhao Y, McMullen K, Rauscher A, Carruthers R, Li DKB, Traboulsee AL, Kolind SH.

Neuroimage Clin. 2016 May 26;11:743-750. doi: 10.1016/j.nicl.2016.05.014. eCollection 2016.

31.

Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Jun 1;90(5):948-54. doi: 10.1016/j.neuron.2016.04.039. Erratum in: Neuron. 2016 Oct 19;92(2):555.

32.

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.

Sadovnick AD, Traboulsee AL, Bernales CQ, Ross JP, Forwell AL, Yee IM, Guillot-Noel L, Fontaine B, Cournu-Rebeix I, Alcina A, Fedetz M, Izquierdo G, Matesanz F, Hilven K, Dubois B, Goris A, Astobiza I, Alloza I, Antigüedad A, Vandenbroeck K, Akkad DA, Aktas O, Blaschke P, Buttmann M, Chan A, Epplen JT, Gerdes LA, Kroner A, Kubisch C, Kümpfel T, Lohse P, Rieckmann P, Zettl UK, Zipp F, Bertram L, Lill CM, Fernandez O, Urbaneja P, Leyva L, Alvarez-Cermeño JC, Arroyo R, Garagorri AM, García-Martínez A, Villar LM, Urcelay E, Malhotra S, Montalban X, Comabella M, Berger T, Fazekas F, Reindl M, Schmied MC, Zimprich A, Vilariño-Güell C.

G3 (Bethesda). 2016 Jul 7;6(7):2073-9. doi: 10.1534/g3.116.030841.

33.

Analysis of CH25H in multiple sclerosis and neuromyelitis optica.

Forwell AL, Bernales CQ, Ross JP, Yee IM, Encarnacion M, Lee JD, Sadovnick AD, Traboulsee AL, Vilariño-Güell C.

J Neuroimmunol. 2016 Feb 15;291:70-2. doi: 10.1016/j.jneuroim.2015.12.014. Epub 2015 Dec 31.

34.

Does hydration status affect MRI measures of brain volume or water content?

Meyers SM, Tam R, Lee JS, Kolind SH, Vavasour IM, Mackie E, Zhao Y, Laule C, Mädler B, Li DK, MacKay AL, Traboulsee AL.

J Magn Reson Imaging. 2016 Aug;44(2):296-304. doi: 10.1002/jmri.25168. Epub 2016 Jan 29.

PMID:
26825048
35.

Multiple measures of corticospinal excitability are associated with clinical features of multiple sclerosis.

Neva JL, Lakhani B, Brown KE, Wadden KP, Mang CS, Ledwell NH, Borich MR, Vavasour IM, Laule C, Traboulsee AL, MacKay AL, Boyd LA.

Behav Brain Res. 2016 Jan 15;297:187-95. doi: 10.1016/j.bbr.2015.10.015. Epub 2015 Oct 20.

36.

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders.

Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, de Seze J, Fujihara K, Greenberg B, Jacob A, Jarius S, Lana-Peixoto M, Levy M, Simon JH, Tenembaum S, Traboulsee AL, Waters P, Wellik KE, Weinshenker BG; International Panel for NMO Diagnosis.

Neurology. 2015 Jul 14;85(2):177-89. doi: 10.1212/WNL.0000000000001729. Epub 2015 Jun 19.

37.

Incidence of Multiple Sclerosis and Related Disorders in Asian Populations of British Columbia.

Lee JD, Guimond C, Yee IM, Vilariño-Güell C, Wu ZY, Traboulsee AL, Sadovnick AD.

Can J Neurol Sci. 2015 Jul;42(4):235-41. doi: 10.1017/cjn.2015.36. Epub 2015 Jun 15.

PMID:
26074012
38.

Progressive multiple sclerosis exhibits decreasing glutamate and glutamine over two years.

MacMillan EL, Tam R, Zhao Y, Vavasour IM, Li DK, Oger J, Freedman MS, Kolind SH, Traboulsee AL.

Mult Scler. 2016 Jan;22(1):112-6. doi: 10.1177/1352458515586086. Epub 2015 May 26.

PMID:
26014604
39.

An assessment of genetic counseling services for individuals with multiple sclerosis.

Skinner S, Guimond C, Butler R, Dwosh E, Traboulsee AL, Sadovnick AD.

J Genet Couns. 2015 Feb;24(1):46-57. doi: 10.1007/s10897-014-9735-2. Epub 2014 Jul 5.

PMID:
24993688
40.

Dehydration affects spinal cord cross-sectional area measurement on MRI in healthy subjects.

Wang C, Tam RC, Mackie E, Li DK, Traboulsee AL.

Spinal Cord. 2014 Aug;52(8):616-20. doi: 10.1038/sc.2014.66. Epub 2014 Apr 29.

PMID:
24777158
41.

Genetic variants in IL2RA and IL7R affect multiple sclerosis disease risk and progression.

Traboulsee AL, Bernales CQ, Ross JP, Lee JD, Sadovnick AD, Vilariño-Güell C.

Neurogenetics. 2014 Aug;15(3):165-9. doi: 10.1007/s10048-014-0403-3. Epub 2014 Apr 26.

42.

Fast computation of myelin maps from MRI T₂ relaxation data using multicore CPU and graphics card parallelization.

Yoo Y, Prasloski T, Vavasour I, MacKay A, Traboulsee AL, Li DK, Tam RC.

J Magn Reson Imaging. 2015 Mar;41(3):700-7. doi: 10.1002/jmri.24604. Epub 2014 Feb 27.

PMID:
24578324
43.

Progressive multiple sclerosis does not associate with rs996343 and rs2046748.

Bernales CQ, Ross JP, Lee JD, Zhao Y, Sadovnick AD, Traboulsee AL, Vilariño-Güell C.

Mult Scler. 2014 May;20(6):766-7. doi: 10.1177/1352458513517280. Epub 2013 Dec 24. No abstract available.

44.

Analysis of CYP27B1 in multiple sclerosis.

Ross JP, Bernales CQ, Lee JD, Sadovnick AD, Traboulsee AL, Vilariño-Güell C.

J Neuroimmunol. 2014 Jan 15;266(1-2):64-6. doi: 10.1016/j.jneuroim.2013.11.006. Epub 2013 Nov 23.

45.

Prevalence of extracranial venous narrowing on catheter venography in people with multiple sclerosis, their siblings, and unrelated healthy controls: a blinded, case-control study.

Traboulsee AL, Knox KB, Machan L, Zhao Y, Yee I, Rauscher A, Klass D, Szkup P, Otani R, Kopriva D, Lala S, Li DK, Sadovnick D.

Lancet. 2014 Jan 11;383(9912):138-45. doi: 10.1016/S0140-6736(13)61747-X. Epub 2013 Oct 9.

PMID:
24119384
46.

Application and a proposed modification of the 2010 McDonald criteria for the diagnosis of multiple sclerosis in a Canadian cohort of patients with clinically isolated syndromes.

Kang H, Metz LM, Traboulsee AL, Eliasziw M, Zhao GJ, Cheng Y, Zhao Y, Li DK; Minocycline in CIS Study Group.

Mult Scler. 2014 Apr;20(4):458-63. doi: 10.1177/1352458513501230. Epub 2013 Aug 22.

PMID:
23970502
47.

Colony stimulation factor 1 receptor (CSF1R) is not a common cause of multiple sclerosis.

Sadovnick AD, Traboulsee AL, Lee JD, Ross JP, Bernales CQ, Vilariño-Güell C.

Eur J Neurol. 2013 Sep;20(9):e115-6. doi: 10.1111/ene.12213. No abstract available.

48.

Spectral-domain optical coherence tomography of retinal nerve fiber layer thickness in NMO patients.

Lange AP, Sadjadi R, Zhu F, Alkabie S, Costello F, Traboulsee AL.

J Neuroophthalmol. 2013 Sep;33(3):213-9. doi: 10.1097/WNO.0b013e31829c510e.

PMID:
23863782
49.

Utility of the Canadian Treatment Optimization Recommendations (TOR) in MS care.

Grand'Maison F, Bhan V, Freedman MS, Myles ML, Patry DG, Selchen DH, Moriarty P, Traboulsee AL.

Can J Neurol Sci. 2013 Jul;40(4):527-35.

PMID:
23786735
50.

Multicenter measurements of myelin water fraction and geometric mean T2 : intra- and intersite reproducibility.

Meyers SM, Vavasour IM, Mädler B, Harris T, Fu E, Li DK, Traboulsee AL, MacKay AL, Laule C.

J Magn Reson Imaging. 2013 Dec;38(6):1445-53. doi: 10.1002/jmri.24106. Epub 2013 Apr 1.

PMID:
23553991

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