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Items: 1 to 50 of 60

1.

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients with Nonalcoholic Steatohepatitis With Cirrhosis And Portal Hypertension.

Chalasani N, Abdelmalek MF, Garcia-Tsao G, Vuppalanchi R, Alkhouri N, Rinella M, Noureddin M, Pyko M, Shiffman M, Sanyal A, Allgood A, Shlevin H, Horton R, Zomer E, Irish W, Goodman Z, Harrison SA, Traber PG.

Gastroenterology. 2019 Dec 5. pii: S0016-5085(19)41895-7. doi: 10.1053/j.gastro.2019.11.296. [Epub ahead of print]

PMID:
31812510
2.

Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial.

Harrison SA, Dennis A, Fiore MM, Kelly MD, Kelly CJ, Paredes AH, Whitehead JM, Neubauer S, Traber PG, Banerjee R.

PLoS One. 2018 Sep 7;13(9):e0203054. doi: 10.1371/journal.pone.0203054. eCollection 2018.

3.

Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis.

Harrison SA, Marri SR, Chalasani N, Kohli R, Aronstein W, Thompson GA, Irish W, Miles MV, Xanthakos SA, Lawitz E, Noureddin M, Schiano TD, Siddiqui M, Sanyal A, Neuschwander-Tetri BA, Traber PG.

Aliment Pharmacol Ther. 2016 Dec;44(11-12):1183-1198. doi: 10.1111/apt.13816. Epub 2016 Oct 24.

4.

Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain.

Miller MC, Ippel H, Suylen D, Klyosov AA, Traber PG, Hackeng T, Mayo KH.

Glycobiology. 2016 Jan;26(1):88-99. doi: 10.1093/glycob/cwv073.

5.

Therapy of experimental NASH and fibrosis with galectin inhibitors.

Traber PG, Zomer E.

PLoS One. 2013 Dec 18;8(12):e83481. doi: 10.1371/journal.pone.0083481. eCollection 2013.

6.

Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease.

Traber PG, Chou H, Zomer E, Hong F, Klyosov A, Fiel MI, Friedman SL.

PLoS One. 2013 Oct 9;8(10):e75361. doi: 10.1371/journal.pone.0075361. eCollection 2013.

7.

Surviving Hurricane Katrina: reconstructing the educational enterprise of Tulane University School of Medicine.

Krane NK, Kahn MJ, Markert RJ, Whelton PK, Traber PG, Taylor IL.

Acad Med. 2007 Aug;82(8):757-62.

PMID:
17762249
8.

DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.

Suh ER, Ha CS, Rankin EB, Toyota M, Traber PG.

J Biol Chem. 2002 Sep 27;277(39):35795-800. Epub 2002 Jul 17.

9.

A novel colonic repressor element regulates intestinal gene expression by interacting with Cux/CDP.

Boudreau F, Rings EH, Swain GP, Sinclair AM, Suh ER, Silberg DG, Scheuermann RH, Traber PG.

Mol Cell Biol. 2002 Aug;22(15):5467-78.

10.

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

Boudreau F, Rings EH, van Wering HM, Kim RK, Swain GP, Krasinski SD, Moffett J, Grand RJ, Suh ER, Traber PG.

J Biol Chem. 2002 Aug 30;277(35):31909-17. Epub 2002 Jun 11.

11.

Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity.

Rings EH, Boudreau F, Taylor JK, Moffett J, Suh ER, Traber PG.

Gastroenterology. 2001 Dec;121(6):1437-50.

PMID:
11729123
13.

Clusterin gene transcription is activated by caudal-related homeobox genes in intestinal epithelium.

Suh E, Wang Z, Swain GP, Tenniswood M, Traber PG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jan;280(1):G149-56.

14.

Cdx1 and cdx2 expression during intestinal development.

Silberg DG, Swain GP, Suh ER, Traber PG.

Gastroenterology. 2000 Oct;119(4):961-71.

PMID:
11040183
15.
16.

The caudal-related homeodomain protein Cdx1 inhibits proliferation of intestinal epithelial cells by down-regulation of D-type cyclins.

Lynch J, Suh ER, Silberg DG, Rulyak S, Blanchard N, Traber PG.

J Biol Chem. 2000 Feb 11;275(6):4499-506.

17.

CREB-binding [corrected] protein interacts with the homeodomain protein Cdx2 and enhances transcriptional activity.

Lorentz O, Suh ER, Taylor JK, Boudreau F, Traber PG.

J Biol Chem. 1999 Mar 12;274(11):7196-9. Erratum in: J Biol Chem 1999 May 7;274(19):13728. Retraction in: J Biol Chem. 2001 Mar 30;276(13):10576.

18.

Gut patterning: the case of the missing cecum.

Traber PG.

Gastroenterology. 1998 Aug;115(2):487-9. No abstract available.

PMID:
9758534
19.

Control of gene expression in intestinal epithelial cells.

Traber PG.

Philos Trans R Soc Lond B Biol Sci. 1998 Jun 29;353(1370):911-4. Review.

20.

Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters.

Taylor JK, Boll W, Levy T, Suh E, Siang S, Mantei N, Traber PG.

DNA Cell Biol. 1997 Dec;16(12):1419-28.

PMID:
9428790
21.

Epithelial cell growth and differentiation. V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium.

Traber PG.

Am J Physiol. 1997 Nov;273(5):G979-81. doi: 10.1152/ajpgi.1997.273.5.G979. Review.

PMID:
9374692
22.

Molecular pathogenesis of colorectal cancer.

Hoops TC, Traber PG.

Hematol Oncol Clin North Am. 1997 Aug;11(4):609-33. Review.

PMID:
9257148
23.

CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium.

Silberg DG, Furth EE, Taylor JK, Schuck T, Chiou T, Traber PG.

Gastroenterology. 1997 Aug;113(2):478-86.

PMID:
9247467
24.

Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter.

Tung J, Markowitz AJ, Silberg DG, Traber PG.

Am J Physiol. 1997 Jul;273(1 Pt 1):G83-92.

PMID:
9252513
25.
26.

Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific.

Taylor JK, Levy T, Suh ER, Traber PG.

Nucleic Acids Res. 1997 Jun 15;25(12):2293-300.

27.

Expression of PRL-1 nuclear PTPase is associated with proliferation in liver but with differentiation in intestine.

Diamond RH, Peters C, Jung SP, Greenbaum LE, Haber BA, Silberg DG, Traber PG, Taub R.

Am J Physiol. 1996 Jul;271(1 Pt 1):G121-9.

PMID:
8760115
28.

cis-Acting elements and transcription factors involved in the intestinal specific expression of the rat calbindin-D9K gene: binding of the intestine-specific transcription factor Cdx-2 to the TATA box.

Lambert M, Colnot S, Suh E, L'Horset F, Blin C, Calliot ME, Raymondjean M, Thomasset M, Traber PG, Perret C.

Eur J Biochem. 1996 Mar 15;236(3):778-88.

29.
30.

Intestine-specific gene transcription.

Traber PG, Silberg DG.

Annu Rev Physiol. 1996;58:275-97. Review.

PMID:
8815796
31.

Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines.

Markowitz AJ, Wu GD, Bader A, Cui Z, Chen L, Traber PG.

Am J Physiol. 1995 Dec;269(6 Pt 1):G925-39.

PMID:
8572224
32.

The Down regulated in Adenoma (dra) gene encodes an intestine-specific membrane sulfate transport protein.

Silberg DG, Wang W, Moseley RH, Traber PG.

J Biol Chem. 1995 May 19;270(20):11897-902.

33.

Possible nizatidine-induced subfulminant hepatic failure.

Chey WD, Kochman ML, Traber PG, Appelman HD, Gumucio JJ.

J Clin Gastroenterol. 1995 Mar;20(2):164-7.

PMID:
7769203
34.

Cancer in inflammatory bowel disease.

Bachwich DR, Lichtenstein GR, Traber PG.

Med Clin North Am. 1994 Nov;78(6):1399-412. Review.

PMID:
7967916
35.

A homeodomain protein related to caudal regulates intestine-specific gene transcription.

Suh E, Chen L, Taylor J, Traber PG.

Mol Cell Biol. 1994 Nov;14(11):7340-51.

36.

Transcriptional regulation of intestinal hydrolase biosynthesis during postnatal development in rats.

Krasinski SD, Estrada G, Yeh KY, Yeh M, Traber PG, Rings EH, Büller HA, Verhave M, Montgomery RK, Grand RJ.

Am J Physiol. 1994 Oct;267(4 Pt 1):G584-94.

PMID:
7943323
37.
38.

Differentiation of intestinal epithelial cells: lessons from the study of intestine-specific gene expression.

Traber PG.

J Lab Clin Med. 1994 Apr;123(4):467-77. Review. No abstract available.

PMID:
8144995
39.

Murine intestinal disaccharidases: identification of structural variants of sucrase-isomaltase complex.

Quezada-Calvillo R, Markowitz AJ, Traber PG, Underdown BJ.

Am J Physiol. 1993 Dec;265(6 Pt 1):G1141-9.

PMID:
8279565
40.

Sucrase-isomaltase gene expression in Barrett's esophagus and adenocarcinoma.

Wu GD, Beer DG, Moore JH, Orringer MB, Appelman HD, Traber PG.

Gastroenterology. 1993 Sep;105(3):837-44.

PMID:
8359653
41.

The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice.

Markowitz AJ, Wu GD, Birkenmeier EH, Traber PG.

Am J Physiol. 1993 Sep;265(3 Pt 1):G526-39.

PMID:
8214074
42.

Expression and regulation of cytochrome P-450I genes (CYP1A1 and CYP1A2) in the rat alimentary tract.

Traber PG, McDonnell WM, Wang W, Florence R.

Biochim Biophys Acta. 1992 Dec 29;1171(2):167-75.

43.

Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract.

McDonnell WM, Scheiman JM, Traber PG.

Gastroenterology. 1992 Nov;103(5):1509-16.

PMID:
1426869
44.

Differential regulation of cytochrome P-450 genes along rat intestinal crypt-villus axis.

Traber PG, Wang W, Yu L.

Am J Physiol. 1992 Aug;263(2 Pt 1):G215-23.

PMID:
1514633
45.
47.
48.

Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt-villus axis.

Traber PG, Gumucio DL, Wang W.

Am J Physiol. 1991 Jun;260(6 Pt 1):G895-903.

PMID:
2058677
49.

Detection of hepatitis C viral RNA by the polymerase chain reaction.

Lucey M, Traber PG.

Hepatology. 1991 Jan;13(1):193-5. No abstract available.

50.

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