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Items: 1 to 50 of 134

1.

Treatment of two mitochondrial disease patients with a combination of febuxostat and inosine that enhances cellular ATP.

Kamatani N, Kushiyama A, Toyo-Oka L, Toyo-Oka T.

J Hum Genet. 2019 Apr;64(4):351-353. doi: 10.1038/s10038-018-0558-0. Epub 2019 Jan 10.

PMID:
30631120
2.

Specific knockdown of delta-sarcoglycan gene in C2C12 in vitro causes post-translational loss of other sarcoglycans without mechanical stress.

Honda M, Hosoda M, Kanzawa N, Tsuchiya T, Toyo-oka T.

Mol Cell Biochem. 2009 Mar;323(1-2):149-59. doi: 10.1007/s11010-008-9975-2. Epub 2008 Dec 16.

PMID:
19083155
3.

Breastfeeding and prevalence of allergic diseases in Japanese university students.

Karino S, Okuda T, Uehara Y, Toyo-oka T.

Ann Allergy Asthma Immunol. 2008 Aug;101(2):153-9. doi: 10.1016/S1081-1206(10)60203-7.

PMID:
18727470
5.

Specific knockdown of m-calpain blocks myogenesis with cDNA deduced from the corresponding RNAi.

Honda M, Masui F, Kanzawa N, Tsuchiya T, Toyo-oka T.

Am J Physiol Cell Physiol. 2008 Apr;294(4):C957-65. doi: 10.1152/ajpcell.00505.2007. Epub 2008 Jan 23.

6.

Which skeletal myoblasts and how to be transplanted for cardiac repair?

Tezuka A, Kawada T, Nakazawa M, Masui F, Konno S, Nitta S, Toyo-Oka T.

Biochem Biophys Res Commun. 2008 Apr 25;369(1):270-6. Epub 2007 Nov 29.

PMID:
18047831
7.

[Myocardial dystrophin and its related proteins].

Toyo-oka T.

Nihon Rinsho. 2007 Apr 28;65 Suppl 4:132-42. Japanese. No abstract available.

PMID:
17508550
8.

Cardiac troponin levels as a preferable biomarker of myocardial cell degradation.

Toyo-oka T, Kumagai H.

Adv Exp Med Biol. 2007;592:241-9. Review. No abstract available.

PMID:
17278369
9.

Focalized contractile impairment at hypertrophied myocardium proven in consideration of wall stress in patients with hypertrophic cardiomyopathy.

Yamazaki T, Suzuki J, Shimamoto R, Tsuji T, Ohmoto Y, Toyo-oka T, Omata M, Ohtomo K, Nagai R.

Int Heart J. 2006 Mar;47(2):247-58.

10.

Changes in the awareness of oral health among new students newly enrolled at the University of Tokyo over the past 15 years.

Hikiji H, Koshikiya N, Fujihara H, Hatano N, Matsuzaki M, Matsuzaki A, Ohki M, Susami T, Takato T, Toyo-oka T.

Int J Dent Hyg. 2005 Aug;3(3):137-44.

PMID:
16451364
11.

Autophagic cardiomyocyte death in cardiomyopathic hamsters and its prevention by granulocyte colony-stimulating factor.

Miyata S, Takemura G, Kawase Y, Li Y, Okada H, Maruyama R, Ushikoshi H, Esaki M, Kanamori H, Li L, Misao Y, Tezuka A, Toyo-Oka T, Minatoguchi S, Fujiwara T, Fujiwara H.

Am J Pathol. 2006 Feb;168(2):386-97.

12.

Gene therapy prevents disruption of dystrophin-related proteins in a model of hereditary dilated cardiomyopathy in hamsters.

Toyo-oka T, Kawada T, Xi H, Nakazawa M, Masui F, Hemmi C, Nakata J, Tezuka A, Iwasawa K, Urabe M, Monahan J, Ozawa K.

Heart Lung Circ. 2002;11(3):174-81.

PMID:
16352094
13.

Endogenous prostaglandin D(2) synthesis decreases vascular cell adhesion molecule-1 expression in human umbilical vein endothelial cells.

Negoro H, Shin WS, Hakamada-Taguchi R, Eguchi N, Urade Y, Goto A, Toyo-Oka T, Fujita T, Omata M, Uehara Y.

Life Sci. 2005 Nov 19;78(1):22-9. Epub 2005 Sep 8.

PMID:
16154157
14.

A novel scheme of dystrophin disruption for the progression of advanced heart failure.

Kawada T, Masui F, Tezuka A, Ebisawa T, Kumagai H, Nakazawa M, Toyo-Oka T.

Biochim Biophys Acta. 2005 Aug 1;1751(1):73-81. Epub 2005 Jan 26. Review.

PMID:
16054019
15.

A novel paradigm for therapeutic basis of advanced heart failure--assessment by gene therapy.

Kawada T, Masui F, Kumagai H, Koshimizu M, Nakazawa M, Toyo-Oka T.

Pharmacol Ther. 2005 Jul;107(1):31-43. Epub 2005 Apr 13. Review.

PMID:
15963350
16.

Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells.

Iida H, Jo T, Iwasawa K, Morita T, Hikiji H, Takato T, Toyo-Oka T, Nagai R, Nakajima T.

Br J Pharmacol. 2005 Sep;146(1):49-59.

17.

Effects of ACE inhibitor and AT1 blocker on dystrophin-related proteins and calpain in failing heart.

Takahashi M, Tanonaka K, Yoshida H, Oikawa R, Koshimizu M, Daicho T, Toyo-Oka T, Takeo S.

Cardiovasc Res. 2005 Feb 1;65(2):356-65.

PMID:
15639474
18.

Ursodeoxycholic acid inhibits endothelin-1 production in human vascular endothelial cells.

Ma J, Iida H, Jo T, Takano H, Oonuma H, Morita T, Toyo-Oka T, Omata M, Nagai R, Okuda Y, Yamada N, Nakajima T.

Eur J Pharmacol. 2004 Nov 28;505(1-3):67-74.

PMID:
15556138
19.

RNAi induction and activation in mammalian muscle cells where Dicer and eIF2C translation initiation factors are barely expressed.

Sago N, Omi K, Tamura Y, Kunugi H, Toyo-oka T, Tokunaga K, Hohjoh H.

Biochem Biophys Res Commun. 2004 Jun 18;319(1):50-7.

PMID:
15158441
20.

Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure: a scheme for the progression of cardiac dysfunction.

Toyo-Oka T, Kawada T, Nakata J, Xie H, Urabe M, Masui F, Ebisawa T, Tezuka A, Iwasawa K, Nakajima T, Uehara Y, Kumagai H, Kostin S, Schaper J, Nakazawa M, Ozawa K.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7381-5. Epub 2004 May 5.

21.

Low-dose carvedilol improves left ventricular function and reduces cardiovascular hospitalization in Japanese patients with chronic heart failure: the Multicenter Carvedilol Heart Failure Dose Assessment (MUCHA) trial.

Hori M, Sasayama S, Kitabatake A, Toyo-oka T, Handa S, Yokoyama M, Matsuzaki M, Takeshita A, Origasa H, Matsui K, Hosoda S; MUCHA Investigators.

Am Heart J. 2004 Feb;147(2):324-30.

PMID:
14760332
22.

[A new paradigm for the progression of advanced heart failure].

Kawada T, Nakazawa M, Toyo-oka T.

Nihon Yakurigaku Zasshi. 2004 Feb;123(2):55-62. Review. Japanese.

PMID:
14745124
23.

High fidelity SNP genotyping using sequence-specific primer elongation and fluorescence correlation spectroscopy.

Hori K, Shin WS, Hemmi C, Toyo-oka T, Makino T.

Curr Pharm Biotechnol. 2003 Dec;4(6):477-84. Review.

PMID:
14683439
24.

Inhibition of hydroxymethylglutaryl-coenzyme a reductase reduces Th1 development and promotes Th2 development.

Hakamada-Taguchi R, Uehara Y, Kuribayashi K, Numabe A, Saito K, Negoro H, Fujita T, Toyo-oka T, Kato T.

Circ Res. 2003 Nov 14;93(10):948-56. Epub 2003 Oct 16.

PMID:
14563711
25.

Decrease in sarcoglycans and dystrophin in failing heart following acute myocardial infarction.

Yoshida H, Takahashi M, Koshimizu M, Tanonaka K, Oikawa R, Toyo-oka T, Takeo S.

Cardiovasc Res. 2003 Aug 1;59(2):419-27.

PMID:
12909325
26.

Sarcolemmal fragility secondary to the degradation of dystrophin in dilated cardiomyopathy, as estimated by electron microscopy.

Kawada T, Hemmi C, Fukuda S, Tezuka A, Iwasawa K, Nakazawa M, Sato H, Toyo-Oka T.

Exp Clin Cardiol. 2003 Summer;8(2):67-70.

27.

Targeting of iNOS with antisense DNA plasmid reduces cytokine-induced inhibition of osteoblastic activity.

Abe T, Hikiji H, Shin WS, Koshikiya N, Shima S, Nakata J, Susami T, Takato T, Toyo-oka T.

Am J Physiol Endocrinol Metab. 2003 Sep;285(3):E614-21. Epub 2003 Mar 25.

28.

Effects of the anti-platelet aggregation drug dilazep on cognitive function in Dahl salt-sensitive rats.

Numabe A, Ara N, Hakamada-Taguchi R, Suzuki N, Hirawa N, Kawabata Y, Negoro T, Nagata T, Goto A, Toyo-Oka T, Fujita T, Uehara Y.

Hypertens Res. 2003 Feb;26(2):185-91.

29.

Nonselective cation currents regulate membrane potential of rabbit coronary arterial cell: modulation by lysophosphatidylcholine.

Terasawa K, Nakajima T, Iida H, Iwasawa K, Oonuma H, Jo T, Morita T, Nakamura F, Fujimori Y, Toyo-oka T, Nagai R.

Circulation. 2002 Dec 10;106(24):3111-9.

PMID:
12473560
30.

Cell density and growth-dependent down-regulation of both intracellular calcium responses to agonist stimuli and expression of smooth-surfaced endoplasmic reticulum in MC3T3-E1 osteoblast-like cells.

Koizumi T, Hikiji H, Shin WS, Takato T, Fukuda S, Abe T, Koshikiya N, Iwasawa K, Toyo-oka T.

J Biol Chem. 2003 Feb 21;278(8):6433-9. Epub 2002 Dec 5.

31.

The relationship between changes in normal-range systolic blood pressure and cognitive function in middle-aged healthy women.

Hakamada-Taguchi R, Uehara Y, Haebara T, Negoro H, Toyo-oka T.

Hypertens Res. 2002 Jul;25(4):565-9.

32.

Endogenous prostaglandin D2 synthesis reduces an increase in plasminogen activator inhibitor-1 following interleukin stimulation in bovine endothelial cells.

Negoro H, Soo Shin W, Hakamada-Taguchi R, Eguchi N, Urade Y, Goto A, Toyo-Oka T, Fujita T, Omata M, Uehara Y.

J Hypertens. 2002 Jul;20(7):1347-54.

PMID:
12131531
33.

Co-culture and crosstalk between endothelial cells and vascular smooth muscle cells mediated by intracellular calcium.

Shin WS, Hemmi C, Toyo-oka T.

Methods Mol Biol. 2002;188:347-57. No abstract available.

PMID:
11987556
34.

Vector analysis of the wall shear rate at the human aortoiliac bifurcation using cine MR velocity mapping.

Tsuji T, Suzuki J, Shimamoto R, Yamazaki T, Nakajima T, Nagai R, Komatsu S, Ohtomo K, Toyo-Oka T, Omata M.

AJR Am J Roentgenol. 2002 Apr;178(4):995-9.

PMID:
11906890
35.

[Somatic gene therapy of dilated cardiomyopathy].

Kawada T, Nakazawa M, Toyo-Oka T.

Nihon Yakurigaku Zasshi. 2002 Jan;119(1):37-44. Japanese.

PMID:
11862755
36.

Rescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy: amelioration of morphological findings, sarcolemmal permeability, cardiac performances, and the prognosis of TO-2 hamsters.

Kawada T, Nakazawa M, Nakauchi S, Yamazaki K, Shimamoto R, Urabe M, Nakata J, Hemmi C, Masui F, Nakajima T, Suzuki J, Monahan J, Sato H, Masaki T, Ozawa K, Toyo-Oka T.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):901-6.

37.

Morphological and physiological restorations of hereditary form of dilated cardiomyopathy by somatic gene therapy.

Kawada T, Sakamoto A, Nakazawa M, Urabe M, Masuda F, Hemmi C, Wang Y, Shin WS, Nakatsuru Y, Sato H, Ozawa K, Toyo-oka T.

Biochem Biophys Res Commun. 2001 Jun 8;284(2):431-5.

PMID:
11394897
38.

Dystrophin disruption might be related to myocardial cell apoptosis caused by isoproterenol.

Xi H, Shin WS, Suzuki J, Nakajima T, Kawada T, Uehara Y, Nakazawa M, Toyo-oka T.

J Cardiovasc Pharmacol. 2000;36 Suppl 2:S25-9.

PMID:
11206716
39.

Crucial role of type 1, but not type 3, inositol 1,4,5-trisphosphate (IP(3)) receptors in IP(3)-induced Ca(2+) release, capacitative Ca(2+) entry, and proliferation of A7r5 vascular smooth muscle cells.

Wang Y, Chen J, Wang Y, Taylor CW, Hirata Y, Hagiwara H, Mikoshiba K, Toyo-oka T, Omata M, Sakaki Y.

Circ Res. 2001 Feb 2;88(2):202-9.

PMID:
11157673
40.

Evaluation of the heart with magnetic resonance imaging.

Suzuki J, Nagai R, Nishikawa J, Ohotomo K, Toyo-Oka T, Omata M.

Jpn Heart J. 2000 Jul;41(4):417-24. Review.

41.

A novel homoplasmic mutation in mtDNA with a single evolutionary origin as a risk factor for cardiomyopathy.

Shin WS, Tanaka M, Suzuki J, Hemmi C, Toyo-oka T.

Am J Hum Genet. 2000 Dec;67(6):1617-20. Epub 2000 Oct 18.

42.

Bile acids increase intracellular Ca(2+) concentration and nitric oxide production in vascular endothelial cells.

Nakajima T, Okuda Y, Chisaki K, Shin WS, Iwasawa K, Morita T, Matsumoto A, Suzuki JI, Suzuki S, Yamada N, Toyo-Oka T, Nagai R, Omata M.

Br J Pharmacol. 2000 Aug;130(7):1457-67.

43.

[Mitochondrial gene mutation].

Shin WS, Toyo-oka T.

Nihon Rinsho. 2000 Jan;58(1):129-33. Review. Japanese.

PMID:
10885300
44.

Autocrine action and its underlying mechanism of nitric oxide on intracellular Ca2+ homeostasis in vascular endothelial cells.

Chen J, Wang Y, Nakajima T, Iwasawa K, Hikiji H, Sunamoto M, Choi DK, Yoshida Y, Sakaki Y, Toyo-Oka T.

J Biol Chem. 2000 Sep 15;275(37):28739-49.

45.

Peroxynitrite production by TNF-alpha and IL-1beta: implication for suppression of osteoblastic differentiation.

Hikiji H, Shin WS, Koizumi T, Takato T, Susami T, Koizumi Y, Okai-Matsuo Y, Toyo-Oka T.

Am J Physiol Endocrinol Metab. 2000 Jun;278(6):E1031-7.

46.

Clinical implication of left precordial T wave inversions in the presence of complete right bundle branch block.

Suzuki J, Shin WS, Shimamoto R, Yamazaki T, Tsuji T, Murakawa Y, Nakajima T, Toyo-oka T, Nishikawa J, Ohotomo K, Nagai R, Omata M.

Jpn Heart J. 1999 Nov;40(6):745-53.

47.

Strain- and age-dependent loss of sarcoglycan complex in cardiomyopathic hamster hearts and its re-expression by delta-sarcoglycan gene transfer in vivo.

Kawada T, Nakatsuru Y, Sakamoto A, Koizumi T, Shin WS, Okai-Matsuo Y, Suzuki J, Uehara Y, Nakazawa M, Sato H, Ishikawa T, Toyo-oka T.

FEBS Lett. 1999 Sep 24;458(3):405-8.

48.

Eicosapentaenoic acid inhibits vasopressin-activated Ca2+ influx and cell proliferation in rat aortic smooth muscle cell lines.

Asano M, Nakajima T, Iwasawa K, Asakura Y, Morita T, Nakamura F, Tomaru T, Wang Y, Goto A, Toyo-oka T, Soma M, Suzuki S, Okuda Y.

Eur J Pharmacol. 1999 Aug 27;379(2-3):199-209.

PMID:
10497907
49.

Long-term inhibition of renin-angiotensin system sustains memory function in aged Dahl rats.

Hirawa N, Uehara Y, Kawabata Y, Numabe A, Gomi T, Ikeda T, Suzuki T, Goto A, Toyo-oka T, Omata M.

Hypertension. 1999 Sep;34(3):496-502.

PMID:
10489400
50.

High salt intake potentiates the renal vascular and glomerular damage caused by low doses of angiotensin II in uni-nephrectomized rats.

Hirawa N, Uehara Y, Kawabata Y, Numabe A, Ogawa N, Gomi T, Ikeda T, Goto A, Toyo-oka T, Omata M.

J Hypertens. 1999 Jul;17(7):923-32.

PMID:
10419065

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