Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49


Non-muscle Myosin II drives vesicle loss during human reticulocyte maturation.

Moura PL, Hawley BR, Mankelow TJ, Griffiths RE, Dobbe JGG, Streekstra GJ, Anstee DJ, Satchwell TJ, Toye AM.

Haematologica. 2018 Aug 3. pii: haematol.2018.199083. doi: 10.3324/haematol.2018.199083. [Epub ahead of print]


Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression.

Gurevich DB, Severn CE, Twomey C, Greenhough A, Cash J, Toye AM, Mellor H, Martin P.

EMBO J. 2018 Jul 2;37(13). pii: e97786. doi: 10.15252/embj.201797786. Epub 2018 Jun 4.


Quantitative measurement of red cell surface protein expression reveals new biomarkers for hereditary spherocytosis.

Huisjes R, Satchwell TJ, Verhagen LP, Schiffelers RM, van Solinge WW, Toye AM, van Wijk R.

Int J Lab Hematol. 2018 Aug;40(4):e74-e77. doi: 10.1111/ijlh.12841. Epub 2018 May 10. No abstract available.


Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing.

Hawksworth J, Satchwell TJ, Meinders M, Daniels DE, Regan F, Thornton NM, Wilson MC, Dobbe JG, Streekstra GJ, Trakarnsanga K, Heesom KJ, Anstee DJ, Frayne J, Toye AM.

EMBO Mol Med. 2018 Jun;10(6). pii: e8454. doi: 10.15252/emmm.201708454.


Transduction with BBF2H7/CREB3L2 upregulates SEC23A protein in erythroblasts and partially corrects the hypo-glycosylation phenotype associated with CDAII.

Pellegrin S, Haydn-Smith KL, Hampton-O'Neil LA, Hawley BR, Heesom KJ, Fermo E, Bianchi P, Toye AM.

Br J Haematol. 2018 Mar 14. doi: 10.1111/bjh.15189. [Epub ahead of print] No abstract available.


Band 3 function and dysfunction in a structural context.

Abbas YM, Toye AM, Rubinstein JL, Reithmeier RAF.

Curr Opin Hematol. 2018 May;25(3):163-170. doi: 10.1097/MOH.0000000000000418.


Quantitative proteomics of plasma vesicles identify novel biomarkers for hemoglobin E/β-thalassemic patients.

Kittivorapart J, Crew VK, Wilson MC, Heesom KJ, Siritanaratkul N, Toye AM.

Blood Adv. 2018 Jan 23;2(2):95-104. doi: 10.1182/bloodadvances.2017011726.


Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages.

Heideveld E, Hampton-O'Neil LA, Cross SJ, van Alphen FPJ, van den Biggelaar M, Toye AM, van den Akker E.

Haematologica. 2018 Mar;103(3):395-405. doi: 10.3324/haematol.2017.179341. Epub 2017 Dec 28.


CD47 surface stability is sensitive to actin disruption prior to inclusion within the band 3 macrocomplex.

Mordue KE, Hawley BR, Satchwell TJ, Toye AM.

Sci Rep. 2017 May 22;7(1):2246. doi: 10.1038/s41598-017-02356-1.


An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells.

Trakarnsanga K, Griffiths RE, Wilson MC, Blair A, Satchwell TJ, Meinders M, Cogan N, Kupzig S, Kurita R, Nakamura Y, Toye AM, Anstee DJ, Frayne J.

Nat Commun. 2017 Mar 14;8:14750. doi: 10.1038/ncomms14750.


Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors.

Severn CE, Macedo H, Eagle MJ, Rooney P, Mantalaris A, Toye AM.

Sci Rep. 2016 Aug 30;6:32149. doi: 10.1038/srep32149.


A new junctional hierarchy.

Satchwell TJ, Toye AM.

Blood. 2016 Jul 7;128(1):11-2. doi: 10.1182/blood-2016-05-711788. No abstract available.


Severe Ankyrin-R deficiency results in impaired surface retention and lysosomal degradation of RhAG in human erythroblasts.

Satchwell TJ, Bell AJ, Hawley BR, Pellegrin S, Mordue KE, van Deursen CT, Braak NH, Huls G, Leers MP, Overwater E, Tamminga RY, van der Zwaag B, Fermo E, Bianchi P, van Wijk R, Toye AM.

Haematologica. 2016 Sep;101(9):1018-27. doi: 10.3324/haematol.2016.146209. Epub 2016 May 31.


Comparison of the Proteome of Adult and Cord Erythroid Cells, and Changes in the Proteome Following Reticulocyte Maturation.

Wilson MC, Trakarnsanga K, Heesom KJ, Cogan N, Green C, Toye AM, Parsons SF, Anstee DJ, Frayne J.

Mol Cell Proteomics. 2016 Jun;15(6):1938-46. doi: 10.1074/mcp.M115.057315. Epub 2016 Mar 22.


The sorting of blood group active proteins during enucleation.

Satchwell TJ, Bell AJ, Toye AM.

ISBT Sci Ser. 2015 Apr 1;10(Suppl 1):163-168.


The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesis.

Satchwell TJ, Hawley BR, Bell AJ, Ribeiro ML, Toye AM.

Haematologica. 2015 Jan;100(1):133-42. doi: 10.3324/haematol.2014.114538. Epub 2014 Oct 24.


Qualitative and quantitative comparison of the proteome of erythroid cells differentiated from human iPSCs and adult erythroid cells by multiplex TMT labelling and nanoLC-MS/MS.

Trakarnsanga K, Wilson MC, Griffiths RE, Toye AM, Carpenter L, Heesom KJ, Parsons SF, Anstee DJ, Frayne J.

PLoS One. 2014 Jul 14;9(7):e100874. doi: 10.1371/journal.pone.0100874. eCollection 2014.


Membrane-wrapping contributions to malaria parasite invasion of the human erythrocyte.

Dasgupta S, Auth T, Gov NS, Satchwell TJ, Hanssen E, Zuccala ES, Riglar DT, Toye AM, Betz T, Baum J, Gompper G.

Biophys J. 2014 Jul 1;107(1):43-54. doi: 10.1016/j.bpj.2014.05.024.


CFTR potentiators partially restore channel function to A561E-CFTR, a cystic fibrosis mutant with a similar mechanism of dysfunction as F508del-CFTR.

Wang Y, Liu J, Loizidou A, Bugeja LA, Warner R, Hawley BR, Cai Z, Toye AM, Sheppard DN, Li H.

Br J Pharmacol. 2014 Oct;171(19):4490-503. doi: 10.1111/bph.12791. Epub 2014 Sep 5.


Relative CO₂/NH₃ permeabilities of human RhAG, RhBG and RhCG.

Geyer RR, Parker MD, Toye AM, Boron WF, Musa-Aziz R.

J Membr Biol. 2013 Dec;246(12):915-26.


Characteristic phenotypes associated with congenital dyserythropoietic anemia (type II) manifest at different stages of erythropoiesis.

Satchwell TJ, Pellegrin S, Bianchi P, Hawley BR, Gampel A, Mordue KE, Budnik A, Fermo E, Barcellini W, Stephens DJ, van den Akker E, Toye AM.

Haematologica. 2013 Nov;98(11):1788-96. doi: 10.3324/haematol.2013.085522. Epub 2013 Aug 9.


Protein distribution during human erythroblast enucleation in vitro.

Bell AJ, Satchwell TJ, Heesom KJ, Hawley BR, Kupzig S, Hazell M, Mushens R, Herman A, Toye AM.

PLoS One. 2013;8(4):e60300. doi: 10.1371/journal.pone.0060300. Epub 2013 Apr 2.


Differential proteomic analysis of human erythroblasts undergoing apoptosis induced by epo-withdrawal.

Pellegrin S, Heesom KJ, Satchwell TJ, Hawley BR, Daniels G, van den Akker E, Toye AM.

PLoS One. 2012;7(6):e38356. doi: 10.1371/journal.pone.0038356. Epub 2012 Jun 18.


Ex-vivo generation of human red cells for transfusion.

Anstee DJ, Gampel A, Toye AM.

Curr Opin Hematol. 2012 May;19(3):163-9. doi: 10.1097/MOH.0b013e328352240a. Review.


HCO(3)(-)-independent conductance with a mutant Na(+)/HCO(3)(-) cotransporter (SLC4A4) in a case of proximal renal tubular acidosis with hypokalaemic paralysis.

Parker MD, Qin X, Williamson RC, Toye AM, Boron WF.

J Physiol. 2012 Apr 15;590(8):2009-34. doi: 10.1113/jphysiol.2011.224733. Epub 2012 Feb 13.


Critical band 3 multiprotein complex interactions establish early during human erythropoiesis.

Satchwell TJ, Bell AJ, Pellegrin S, Kupzig S, Ridgwell K, Daniels G, Anstee DJ, van den Akker E, Toye AM.

Blood. 2011 Jul 7;118(1):182-191. doi: 10.1182/blood-2010-10-314187. Epub 2011 Apr 28.


Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod.

Wu F, Satchwell TJ, Toye AM.

Biochem Cell Biol. 2011 Apr;89(2):106-14. doi: 10.1139/o10-146. Review.


Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney.

Su Y, Blake-Palmer KG, Fry AC, Best A, Brown AC, Hiemstra TF, Horita S, Zhou A, Toye AM, Karet FE.

Am J Physiol Renal Physiol. 2011 Jan;300(1):F157-66. doi: 10.1152/ajprenal.00228.2010. Epub 2010 Oct 27.


Anion exchanger 1 interacts with nephrin in podocytes.

Wu F, Saleem MA, Kampik NB, Satchwell TJ, Williamson RC, Blattner SM, Ni L, Toth T, White G, Young MT, Parker MD, Alper SL, Wagner CA, Toye AM.

J Am Soc Nephrol. 2010 Sep;21(9):1456-67. doi: 10.1681/ASN.2009090921. Epub 2010 Jun 24.


The majority of the in vitro erythroid expansion potential resides in CD34(-) cells, outweighing the contribution of CD34(+) cells and significantly increasing the erythroblast yield from peripheral blood samples.

van den Akker E, Satchwell TJ, Pellegrin S, Daniels G, Toye AM.

Haematologica. 2010 Sep;95(9):1594-8. doi: 10.3324/haematol.2009.019828. Epub 2010 Apr 7.


Band 3 multiprotein complexes in the red cell membrane; of mice and men.

van den Akker E, Satchwell TJ, Williamson RC, Toye AM.

Blood Cells Mol Dis. 2010 Jun 15;45(1):1-8. doi: 10.1016/j.bcmd.2010.02.019. Epub 2010 Mar 25. Review.


Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2).

van den Akker E, Satchwell TJ, Pellegrin S, Flatt JF, Maigre M, Daniels G, Delaunay J, Bruce LJ, Toye AM.

Haematologica. 2010 Aug;95(8):1278-86. doi: 10.3324/haematol.2009.021063. Epub 2010 Feb 23.


RhCG is the major putative ammonia transporter expressed in the human kidney, and RhBG is not expressed at detectable levels.

Brown AC, Hallouane D, Mawby WJ, Karet FE, Saleem MA, Howie AJ, Toye AM.

Am J Physiol Renal Physiol. 2009 Jun;296(6):F1279-90. doi: 10.1152/ajprenal.00013.2009. Epub 2009 Apr 8.


Protein 4.2: a complex linker.

Satchwell TJ, Shoemark DK, Sessions RB, Toye AM.

Blood Cells Mol Dis. 2009 May-Jun;42(3):201-10. doi: 10.1016/j.bcmd.2009.01.005. Epub 2009 Mar 9. Review.


Human kidney anion exchanger 1 localisation in MDCK cells is controlled by the phosphorylation status of two critical tyrosines.

Williamson RC, Brown AC, Mawby WJ, Toye AM.

J Cell Sci. 2008 Oct 15;121(Pt 20):3422-32. doi: 10.1242/jcs.035584. Epub 2008 Sep 30.


Glycophorin A: Band 3 aid.

Williamson RC, Toye AM.

Blood Cells Mol Dis. 2008 Jul-Aug;41(1):35-43. doi: 10.1016/j.bcmd.2008.01.001. Epub 2008 Mar 4. Review.


Band 3 Courcouronnes (Ser667Phe): a trafficking mutant differentially rescued by wild-type band 3 and glycophorin A.

Toye AM, Williamson RC, Khanfar M, Bader-Meunier B, Cynober T, Thibault M, Tchernia G, Déchaux M, Delaunay J, Bruce LJ.

Blood. 2008 Jun 1;111(11):5380-9. doi: 10.1182/blood-2007-07-099473. Epub 2008 Jan 3.


Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain.

McKibbin C, Toye AM, Reeves PJ, Khorana HG, Edwards PC, Villa C, Booth PJ.

J Mol Biol. 2007 Dec 14;374(5):1309-18. Epub 2007 Oct 10.


The human NBCe1-A mutant R881C, associated with proximal renal tubular acidosis, retains function but is mistargeted in polarized renal epithelia.

Toye AM, Parker MD, Daly CM, Lu J, Virkki LV, Pelletier MF, Boron WF.

Am J Physiol Cell Physiol. 2006 Oct;291(4):C788-801. Epub 2006 May 17.


Renal tubular acidosis: developments in our understanding of the molecular basis.

Laing CM, Toye AM, Capasso G, Unwin RJ.

Int J Biochem Cell Biol. 2005 Jun;37(6):1151-61. Review.


Protein-4.2 association with band 3 (AE1, SLCA4) in Xenopus oocytes: effects of three natural protein-4.2 mutations associated with hemolytic anemia.

Toye AM, Ghosh S, Young MT, Jones GK, Sessions RB, Ramaugé M, Leclerc P, Basu J, Delaunay J, Tanner MJ.

Blood. 2005 May 15;105(10):4088-95. Epub 2005 Feb 3.


An N-terminal GFP tag does not alter the functional expression to the plasma membrane of red cell and kidney anion exchanger (AE1) in mammalian cells.

Beckmann R, Toye AM, Smythe JS, Anstee DJ, Tanner MJ.

Mol Membr Biol. 2002 Jul-Sep;19(3):187-200.


Band 3 mutations, distal renal tubular acidosis, and Southeast Asian ovalocytosis.

Wrong O, Bruce LJ, Unwin RJ, Toye AM, Tanner MJ.

Kidney Int. 2002 Jul;62(1):10-9. Review.


Red-cell glycophorin A-band 3 interactions associated with the movement of band 3 to the cell surface.

Young MT, Beckmann R, Toye AM, Tanner MJ.

Biochem J. 2000 Aug 15;350 Pt 1:53-60.


Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells.

Bruce LJ, Wrong O, Toye AM, Young MT, Ogle G, Ismail Z, Sinha AK, McMaster P, Hwaihwanje I, Nash GB, Hart S, Lavu E, Palmer R, Othman A, Unwin RJ, Tanner MJ.

Biochem J. 2000 Aug 15;350 Pt 1:41-51.


Keratinocyte superoxide generation.

Turner CP, Toye AM, Jones OT.

Free Radic Biol Med. 1998 Feb;24(3):401-7.


Supplemental Content

Support Center