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Items: 21


Tagging and Enriching Proteins Enables Cell-Specific Proteomics.

Elliott TS, Bianco A, Townsley FM, Fried SD, Chin JW.

Cell Chem Biol. 2016 Jul 21;23(7):805-815. doi: 10.1016/j.chembiol.2016.05.018.


Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal.

Elliott TS, Townsley FM, Bianco A, Ernst RJ, Sachdeva A, Elsässer SJ, Davis L, Lang K, Pisa R, Greiss S, Lilley KS, Chin JW.

Nat Biotechnol. 2014 May;32(5):465-72. doi: 10.1038/nbt.2860. Epub 2014 Apr 13.


Molecular basis for modulation of the p53 target selectivity by KLF4.

Brandt T, Townsley FM, Teufel DP, Freund SM, Veprintsev DB.

PLoS One. 2012;7(10):e48252. doi: 10.1371/journal.pone.0048252. Epub 2012 Oct 30.


Expanding the genetic code of Drosophila melanogaster.

Bianco A, Townsley FM, Greiss S, Lang K, Chin JW.

Nat Chem Biol. 2012 Sep;8(9):748-50. doi: 10.1038/nchembio.1043. Epub 2012 Aug 5.


Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms.

Rajagopalan S, Sade RS, Townsley FM, Fersht AR.

Nucleic Acids Res. 2010 Jan;38(3):893-906. doi: 10.1093/nar/gkp1041. Epub 2009 Nov 20.


Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.

Wong TS, Rajagopalan S, Freund SM, Rutherford TJ, Andreeva A, Townsley FM, Petrovich M, Fersht AR.

Nucleic Acids Res. 2009 Nov;37(20):6765-83. doi: 10.1093/nar/gkp750. Epub 2009 Sep 15.


Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation.

Burge S, Teufel DP, Townsley FM, Freund SM, Bycroft M, Fersht AR.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3142-7. doi: 10.1073/pnas.0900383106. Epub 2009 Feb 13.


Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53.

Wong TS, Rajagopalan S, Townsley FM, Freund SM, Petrovich M, Loakes D, Fersht AR.

Nucleic Acids Res. 2009 Feb;37(2):568-81. doi: 10.1093/nar/gkn974. Epub 2008 Dec 9.


The novel p53 isoform "delta p53" is a misfolded protein and does not bind the p21 promoter site.

García-Alai MM, Tidow H, Natan E, Townsley FM, Veprintsev DB, Fersht AR.

Protein Sci. 2008 Oct;17(10):1671-8. doi: 10.1110/ps.036996.108. Epub 2008 Jul 11.


Structural consequences of nucleophosmin mutations in acute myeloid leukemia.

Grummitt CG, Townsley FM, Johnson CM, Warren AJ, Bycroft M.

J Biol Chem. 2008 Aug 22;283(34):23326-32. doi: 10.1074/jbc.M801706200. Epub 2008 May 29.


Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function.

Townsley FM, Cliffe A, Bienz M.

Nat Cell Biol. 2004 Jul;6(7):626-33. Epub 2004 Jun 20.


Pygopus residues required for its binding to Legless are critical for transcription and development.

Townsley FM, Thompson B, Bienz M.

J Biol Chem. 2004 Feb 13;279(7):5177-83. Epub 2003 Nov 11.


Cdc20 associates with the kinase aurora2/Aik.

Farruggio DC, Townsley FM, Ruderman JV.

Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7306-11.


The cyclin-dependent kinase inhibitor p27(Kip1) induces N-terminal proteolytic cleavage of cyclin A.

Bastians H, Townsley FM, Ruderman JV.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15374-81.


Proteolytic ratchets that control progression through mitosis.

Townsley FM, Ruderman JV.

Trends Cell Biol. 1998 Jun;8(6):238-44. Review.


Functional analysis of the Saccharomyces cerevisiae UBC11 gene.

Townsley FM, Ruderman JV.

Yeast. 1998 Jun 15;14(8):747-57.


Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase.

Townsley FM, Aristarkhov A, Beck S, Hershko A, Ruderman JV.

Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2362-7.


Retrieval of HDEL proteins is required for growth of yeast cells.

Townsley FM, Frigerio G, Pelham HR.

J Cell Biol. 1994 Oct;127(1):21-8.


The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast.

Townsley FM, Pelham HR.

Eur J Cell Biol. 1994 Jun;64(1):211-6. No abstract available.


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