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Hyperbaric therapy provides no benefit for skeletal muscle and respiratory function and accelerates cardiac injury in mdx mice.

Fischer KD, Heitzman JA, Townsend D.

Sci Rep. 2019 Aug 23;9(1):12306. doi: 10.1038/s41598-019-48744-7.


Cardiac Pathophysiology and the Future of Cardiac Therapies in Duchenne Muscular Dystrophy.

Meyers TA, Townsend D.

Int J Mol Sci. 2019 Aug 22;20(17). pii: E4098. doi: 10.3390/ijms20174098. Review.


Genome wide analysis of hnRNP binding to HIV-1 RNA reveals a key role for hnRNP H1 in alternative viral mRNA splicing.

Kutluay SB, Emery A, Penumutchu S, Townsend D, Tenneti K, Madison MK, Stukenbroeker AM, Powell C, Jannain D, Tolbert BS, Swanstrom RI, Bieniasz PD.

J Virol. 2019 Aug 14. pii: JVI.01048-19. doi: 10.1128/JVI.01048-19. [Epub ahead of print]


Folate-coated, long-circulating and pH-sensitive liposomes enhance doxorubicin antitumor effect in a breast cancer animal model.

de Oliveira Silva J, Fernandes RS, Ramos Oda CM, Ferreira TH, Machado Botelho AF, Martins Melo M, de Miranda MC, Assis Gomes D, Dantas Cassali G, Townsend DM, Rubello D, Oliveira MC, de Barros ALB.

Biomed Pharmacother. 2019 Aug 7;118:109323. doi: 10.1016/j.biopha.2019.109323. [Epub ahead of print]


Using video modeling to teach play comments to dyads with ASD.

Ezzeddine EW, DeBar RM, Reeve SA, Townsend DB.

J Appl Behav Anal. 2019 Aug 4. doi: 10.1002/jaba.621. [Epub ahead of print]


Intraoperative continuous renal replacement therapy during liver transplantation: a pilot randomized-controlled trial (INCEPTION).

Karvellas CJ, Taylor S, Bigam D, Kneteman NM, Shapiro AMJ, Romanovsky A, Gibney RTN, Townsend DR, Meeberg G, Özelsel T, Bishop E, Bagshaw SM.

Can J Anaesth. 2019 Oct;66(10):1151-1161. doi: 10.1007/s12630-019-01454-0. Epub 2019 Jul 26.


Racial disparities, cancer and response to oxidative stress.

Zhang J, Ye ZW, Townsend DM, Hughes-Halbert C, Tew KD.

Adv Cancer Res. 2019;144:343-383. doi: 10.1016/bs.acr.2019.03.012. Epub 2019 Apr 23.


The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging.

Rahman WT, Wale DJ, Viglianti BL, Townsend DM, Manganaro MS, Gross MD, Wong KK, Rubello D.

Biomed Pharmacother. 2019 Sep;117:109168. doi: 10.1016/j.biopha.2019.109168. Epub 2019 Jul 1. Review.


Brown Adipose Tissue: Multimodality Evaluation by PET, MRI, Infrared Thermography, and Whole-Body Calorimetry (TACTICAL-II).

Sun L, Verma S, Michael N, Chan SP, Yan J, Sadananthan SA, Camps SG, Goh HJ, Govindharajulu P, Totman J, Townsend D, Goh JP, Sun L, Boehm BO, Lim SC, Sze SK, Henry CJ, Hu HH, Velan SS, Leow MK.

Obesity (Silver Spring). 2019 Sep;27(9):1434-1442. doi: 10.1002/oby.22560. Epub 2019 Jul 13.


Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1.

Zhang L, Zhang J, Ye Z, Manevich Y, Ball LE, Bethard JR, Jiang YL, Broome AM, Dalton AC, Wang GY, Townsend DM, Tew KD.

Cancer Res. 2019 Aug 15;79(16):4072-4085. doi: 10.1158/0008-5472.CAN-18-3503. Epub 2019 Jun 21.


Findings from Quality Improvement Initiatives to Assess and Improve PET/CT FDG Injection Infiltration Rates in Multiple Centers.

Wong TZ, Benefield T, Masters SC, Kiser JW, Crowley JR, Osborne D, Mawlawi O, Barnwell J, Gupta P, Mintz A, Ryan KA kryan@luce, Perrin SR, Lattanze RK, Townsend DW.

J Nucl Med Technol. 2019 Jun 10. pii: jnmt.119.228098. doi: 10.2967/jnmt.119.228098. [Epub ahead of print]


Diuresis renography in equivocal urinary tract obstruction. A historical perspective.

Tartaglione G, Townsend DM, Bassi PF, Delgado Bolton RC, Giammarile F, Rubello D.

Biomed Pharmacother. 2019 Aug;116:108981. doi: 10.1016/j.biopha.2019.108981. Epub 2019 May 25. Review.


Oxidative stress induces senescence in breast cancer stem cells.

Zhong G, Qin S, Townsend D, Schulte BA, Tew KD, Wang GY.

Biochem Biophys Res Commun. 2019 Jul 5;514(4):1204-1209. doi: 10.1016/j.bbrc.2019.05.098. Epub 2019 May 17.


The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix.

Passos da Silva D, Matwichuk ML, Townsend DO, Reichhardt C, Lamba D, Wozniak DJ, Parsek MR.

Nat Commun. 2019 May 16;10(1):2183. doi: 10.1038/s41467-019-10201-4.


A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities.

Bartolini D, Wang Y, Zhang J, Giustarini D, Rossi R, Wang GY, Torquato P, Townsend DM, Tew KD, Galli F.

PLoS One. 2019 Apr 29;14(4):e0205626. doi: 10.1371/journal.pone.0205626. eCollection 2019.


Delivering Cognitive Behavioral Therapy for Insomnia in the Real World: Considerations and Controversies.

Buenaver LF, Townsend D, Ong JC.

Sleep Med Clin. 2019 Jun;14(2):275-281. doi: 10.1016/j.jsmc.2019.01.008. Epub 2019 Mar 29. Review.


Reduced insulin sensitivity in young, normoglycaemic subjects alters microvascular tissue oxygenation during postocclusive reactive hyperaemia.

Townsend DK, Deysher DM, Wu EE, Barstow TJ.

Exp Physiol. 2019 Jun;104(6):967-974. doi: 10.1113/EP087216. Epub 2019 Apr 29.


Effect of assuming constant tissue scattering on measured tissue oxygenation values during tissue ischemia and vascular reperfusion.

Hammer SM, Hueber DM, Townsend DK, Huckaby LM, Alexander AM, Didier KD, Barstow TJ.

J Appl Physiol (1985). 2019 Apr 18. doi: 10.1152/japplphysiol.01138.2018. [Epub ahead of print]


Dynamics of electronically excited states in the eumelanin building block 5,6-dihydroxyindole.

Crane SW, Ghafur O, Cowie TY, Lindsay AG, Thompson JOF, Greenwood JB, Bebbington MWP, Townsend D.

Phys Chem Chem Phys. 2019 Apr 21;21(15):8152-8160. doi: 10.1039/c9cp00620f. Epub 2019 Apr 1.


Effects of a problem-solving strategy on the independent completion of vocational tasks by adolescents with autism spectrum disorder.

Lora CC, Kisamore AN, Reeve KF, Townsend DB.

J Appl Behav Anal. 2019 Apr 1. doi: 10.1002/jaba.558. [Epub ahead of print]


Low dose positron emission tomography emulation from decimated high statistics: A clinical validation study.

Schaefferkoetter J, Nai YH, Reilhac A, Townsend DW, Eriksson L, Conti M.

Med Phys. 2019 Jun;46(6):2638-2645. doi: 10.1002/mp.13517. Epub 2019 May 3.


Pharmacology of ME-344, a novel cytotoxic isoflavone.

Zhang L, Zhang J, Ye Z, Townsend DM, Tew KD.

Adv Cancer Res. 2019;142:187-207. doi: 10.1016/bs.acr.2019.01.005. Epub 2019 Mar 6.


Effects of plasma glucose levels on regional cerebral 18F-fluorodeoxyglucose uptake: Implications for dementia evaluation with brain PET imaging.

Viglianti BL, Wale DJ, Ma T, Johnson TD, Bohnen NI, Wong KK, Ky C, Frey KA, Townsend DM, Rubello D, Gross MD.

Biomed Pharmacother. 2019 Apr;112:108628. doi: 10.1016/j.biopha.2019.108628. Epub 2019 Feb 20.


Vacuum ultraviolet excited state dynamics of small amides.

Larsen MAB, Sølling TI, Forbes R, Boguslavskiy AE, Makhija V, Veyrinas K, Lausten R, Stolow A, Zawadzki MM, Saalbach L, Kotsina N, Paterson MJ, Townsend D.

J Chem Phys. 2019 Feb 7;150(5):054301. doi: 10.1063/1.5079721.


3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish.

Park KH, Ye ZW, Zhang J, Hammad SM, Townsend DM, Rockey DC, Kim SH.

Sci Rep. 2019 Feb 4;9(1):1138. doi: 10.1038/s41598-018-37946-0.


Ultrafast Molecular Spectroscopy Using a Hollow-Core Photonic Crystal Fiber Light Source.

Kotsina N, Belli F, Gao SF, Wang YY, Wang P, Travers JC, Townsend D.

J Phys Chem Lett. 2019 Feb 21;10(4):715-720. doi: 10.1021/acs.jpclett.8b03777. Epub 2019 Feb 1.


Sub-clinical abnormalities detected by PET/MRI in household tuberculosis contacts.

Molton JS, Thomas BA, Pang Y, Khor LK, Hallinan J, Naftalin CM, Totman JJ, Townsend DW, Lim TK, Chee CBE, Wang YT, Paton NI.

BMC Infect Dis. 2019 Jan 24;19(1):83. doi: 10.1186/s12879-019-3705-0.


Acute AT1R blockade prevents isoproterenol-induced injury in mdx hearts.

Meyers TA, Heitzman JA, Krebsbach AM, Aufdembrink LM, Hughes R, Bartolomucci A, Townsend D.

J Mol Cell Cardiol. 2019 Mar;128:51-61. doi: 10.1016/j.yjmcc.2019.01.013. Epub 2019 Jan 19.


Correlation Between Personal Health History and Depression Self-Care Practices and Depression Screening Among African Americans With Chronic Conditions.

Barnes PA, Mayo-Gamble TL, Harris D, Townsend D.

Prev Chronic Dis. 2018 Dec 6;15:E149. doi: 10.5888/pcd15.170581.


Usefulness of Topically Applied Sensors to Assess the Quality of 18F-FDG Injections and Validation Against Dynamic Positron Emission Tomography (PET) Images.

Lattanze RK, Osman MM, Ryan KA, Frye S, Townsend DW.

Front Med (Lausanne). 2018 Nov 1;5:303. doi: 10.3389/fmed.2018.00303. eCollection 2018.


Comparison of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Management Strategies Before Cardiac Surgery: A Pilot Randomized Controlled Registry Trial.

van Diepen S, Norris CM, Zheng Y, Nagendran J, Graham MM, Gaete Ortega D, Townsend DR, Ezekowitz JA, Bagshaw SM.

J Am Heart Assoc. 2018 Oct 16;7(20):e009917. doi: 10.1161/JAHA.118.009917.


Orientation of a Diagnostic Ligand Bound to Macroscopically Aligned Amyloid-β Fibrils Determined by Solid-State NMR.

Townsend D, Hughes E, Stewart KL, Griffin JM, Radford SE, Middleton DA.

J Phys Chem Lett. 2018 Nov 15;9(22):6611-6615. doi: 10.1021/acs.jpclett.8b02448. Epub 2018 Nov 6.


Editorial: Redox and Metabolic Circuits in Cancer.

Rizza S, Rasola A, Townsend DM, Filomeni G.

Front Oncol. 2018 Sep 26;8:403. doi: 10.3389/fonc.2018.00403. eCollection 2018. No abstract available.


Distribution and Bioavailability of Trace Metals in Shallow Sediments from Grand Lake, Oklahoma.

Morrison S, Nikolai S, Townsend D, Belden J.

Arch Environ Contam Toxicol. 2019 Jan;76(1):31-41. doi: 10.1007/s00244-018-0559-1. Epub 2018 Sep 18.


Integrative effects of dystrophin loss on metabolic function of the mdx mouse.

Strakova J, Kamdar F, Kulhanek D, Razzoli M, Garry DJ, Ervasti JM, Bartolomucci A, Townsend D.

Sci Rep. 2018 Sep 11;8(1):13624. doi: 10.1038/s41598-018-31753-3.


Influence of PEG coating on the biodistribution and tumor accumulation of pH-sensitive liposomes.

Nunes SS, Fernandes RS, Cavalcante CH, da Costa César I, Leite EA, Lopes SCA, Ferretti A, Rubello D, Townsend DM, de Oliveira MC, Cardoso VN, de Barros ALB.

Drug Deliv Transl Res. 2019 Feb;9(1):123-130. doi: 10.1007/s13346-018-0583-8.


Stage Salience and Situational Likelihood in the Formation of Situation Models during Sentence Comprehension.

Townsend DJ.

Lingua. 2018 Apr;206:1-20. doi: 10.1016/j.lingua.2018.01.002. Epub 2018 Feb 17.


Targeting redox regulation to treat substance use disorder using N-acetylcysteine.

Womersley JS, Townsend DM, Kalivas PW, Uys JD.

Eur J Neurosci. 2019 Aug;50(3):2538-2551. doi: 10.1111/ejn.14130. Epub 2018 Sep 24. Review.


Predictors of confidence in anatomy knowledge for work as a junior doctor: a national survey of Australian medical students.

Farey JE, Bui DT, Townsend D, Sureshkumar P, Carr S, Roberts C.

BMC Med Educ. 2018 Jul 31;18(1):174. doi: 10.1186/s12909-018-1280-5.


Estimation of the prevalence of cholesteryl ester storage disorder in a cohort of patients with clinical features of familial hypercholesterolaemia.

Ashfield-Watt P, Haralambos K, Edwards R, Townsend D, Gingell R, Wa Li K, Humphries SE, McDowell I.

Ann Clin Biochem. 2019 Jan;56(1):112-117. doi: 10.1177/0004563218793165. Epub 2018 Aug 8.


Ultraviolet relaxation dynamics in uracil: Time-resolved photoion yield studies using a laser-based thermal desorption source.

Ghafur O, Crane SW, Ryszka M, Bockova J, Rebelo A, Saalbach L, De Camillis S, Greenwood JB, Eden S, Townsend D.

J Chem Phys. 2018 Jul 21;149(3):034301. doi: 10.1063/1.5034419.


Effect of Monacolin K and COQ10 supplementation in hypertensive and hypercholesterolemic subjects with metabolic syndrome.

Mazza A, Lenti S, Schiavon L, Di Giacomo E, Tomasi M, Manunta R, Torin G, Townsend DM, Rubello D.

Biomed Pharmacother. 2018 Sep;105:992-996. doi: 10.1016/j.biopha.2018.06.076. Epub 2018 Jun 19.


Frequency and nature of potentially harmful preventable problems in primary care from the patient's perspective with clinician review: a population-level survey in Great Britain.

Stocks SJ, Donnelly A, Esmail A, Beresford J, Luty S, Deacon R, Danczak A, Mann N, Townsend D, Ashley J, Gamble C, Bowie P, Campbell SM.

BMJ Open. 2018 Jun 13;8(6):e020952. doi: 10.1136/bmjopen-2017-020952.


α- Tocopherol succinate loaded nano-structed lipid carriers improves antitumor activity of doxorubicin in breast cancer models in vivo.

Fernandes RS, Silva JO, Seabra HA, Oliveira MS, Carregal VM, Vilela JMC, Andrade MS, Townsend DM, Colletti PM, Leite EA, Cardoso VN, Ferreira LAM, Rubello D, Barros ALB.

Biomed Pharmacother. 2018 Jul;103:1348-1354. doi: 10.1016/j.biopha.2018.04.139. Epub 2018 May 7.


Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin.

Townsend D, Hughes E, Akien G, Stewart KL, Radford SE, Rochester D, Middleton DA.

J Biol Chem. 2018 Aug 17;293(33):12877-12893. doi: 10.1074/jbc.RA118.002038. Epub 2018 May 31.


MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation.

Bräutigam L, Zhang J, Dreij K, Spahiu L, Holmgren A, Abe H, Tew KD, Townsend DM, Kelner MJ, Morgenstern R, Johansson K.

Redox Biol. 2018 Jul;17:171-179. doi: 10.1016/j.redox.2018.04.013. Epub 2018 Apr 16.


Insulin resistance and metabolic syndrome criteria in lean, normoglycemic college-age subjects.

Townsend DK, McGregor K, Wu E, Cialkowski K, Haub MD, Barstow TJ.

Diabetes Metab Syndr. 2018 Sep;12(5):609-616. doi: 10.1016/j.dsx.2018.03.025. Epub 2018 Mar 31.


Development of a Dedicated Rebinner with Rigid Motion Correction for the mMR PET/MR Scanner, and Validation in a Large Cohort of 11C-PIB Scans.

Reilhac A, Merida I, Irace Z, Stephenson MC, Weekes AA, Chen C, Totman JJ, Townsend DW, Fayad H, Costes N.

J Nucl Med. 2018 Nov;59(11):1761-1767. doi: 10.2967/jnumed.117.206375. Epub 2018 Apr 13.


Multi institutional quantitative phantom study of yttrium-90 PET in PET/MRI: the MR-QUEST study.

Maughan NM, Eldib M, Faul D, Conti M, Elschot M, Knešaurek K, Leek F, Townsend D, DiFilippo FP, Jackson K, Nekolla SG, Lukas M, Tapner M, Parikh PJ, Laforest R.

EJNMMI Phys. 2018 Apr 4;5(1):7. doi: 10.1186/s40658-018-0206-y.


An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation.

Zhang J, Ye ZW, Singh S, Townsend DM, Tew KD.

Free Radic Biol Med. 2018 May 20;120:204-216. doi: 10.1016/j.freeradbiomed.2018.03.038. Epub 2018 Mar 23. Review.

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