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Clinical Potential of Targeting Fibroblast Growth Factor-23 and αKlotho in the Treatment of Uremic Cardiomyopathy.

Law JP, Price AM, Pickup L, Radhakrishnan A, Weston C, Jones AM, McGettrick HM, Chua W, Steeds RP, Fabritz L, Kirchhof P, Pavlovic D, Townend JN, Ferro CJ.

J Am Heart Assoc. 2020 Apr 7;9(7):e016041. doi: 10.1161/JAHA.120.016041. Epub 2020 Mar 26.


Anticoagulant strategies for the patient with chronic kidney disease.

Law JP, Pickup L, Townend JN, Ferro CJ.

Clin Med (Lond). 2020 Mar;20(2):151-155. doi: 10.7861/clinmed.2019-0445.


What is the cause of hypotension? A rare complication of percutaneous coronary intervention of a chronic total occlusion: a case report.

Vetrugno V, Sharma H, Townend JN, Khan SQ.

Eur Heart J Case Rep. 2019 Oct 22;3(4):1-5. doi: 10.1093/ehjcr/ytz184. eCollection 2019 Dec.


Myocardial characterization in pre-dialysis chronic kidney disease: a study of prevalence, patterns and outcomes.

Price AM, Hayer MK, Vijapurapu R, Fyyaz SA, Moody WE, Ferro CJ, Townend JN, Steeds RP, Edwards NC.

BMC Cardiovasc Disord. 2019 Dec 16;19(1):295. doi: 10.1186/s12872-019-1256-3.


Sudden cardiac death in chronic renal disease: aetiology and risk reduction strategies.

Pickup LC, Law JP, Townend JN, Ferro CJ.

Nephrol Dial Transplant. 2019 Nov 20. pii: gfz232. doi: 10.1093/ndt/gfz232. [Epub ahead of print] No abstract available.


Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor?

Pickup L, Radhakrishnan A, Townend JN, Ferro CJ.

Curr Opin Nephrol Hypertens. 2019 Nov;28(6):527-536. doi: 10.1097/MNH.0000000000000535.


VAD and CHIPS please.

Townend JN, Nadir A, George S, Khan SQ.

Int J Cardiol. 2019 Oct 15;293:105-106. doi: 10.1016/j.ijcard.2019.07.036. Epub 2019 Jul 12. No abstract available.


Early effects of kidney transplantation on the heart - A cardiac magnetic resonance multi-parametric study.

Hayer MK, Radhakrishnan A, Price AM, Baig S, Liu B, Ferro CJ, Captur G, Townend JN, Moon JC, Edwards NC, Steeds RP.

Int J Cardiol. 2019 Oct 15;293:272-277. doi: 10.1016/j.ijcard.2019.06.007. Epub 2019 Jun 4.


Coronary microvascular dysfunction: a key step in the development of uraemic cardiomyopathy?

Radhakrishnan A, Pickup LC, Price AM, Law JP, Edwards NC, Steeds RP, Ferro CJ, Townend JN.

Heart. 2019 Sep;105(17):1302-1309. doi: 10.1136/heartjnl-2019-315138. Epub 2019 Jun 25. Review.


Measuring frailty in patients undergoing TAVI: how and why?

Townend JN, Ludman PF, Doshi SN.

Eur Heart J. 2019 Jul 14;40(27):2240-2242. doi: 10.1093/eurheartj/ehz382. No abstract available.


Comparison of Routine Versus Selective Glycoprotein IIb/IIIa Inhibitors Usage in Primary Percutaneous Coronary Intervention (from the British Cardiovascular Interventional Society).

Orzalkiewicz M, Hodson J, Kwok CS, Ludman PF, Giblett JP, George S, Doshi SN, Khan SQ, Kinnaird T, Hildick-Smith D, Townend JN, Mamas MA, Calvert PA.

Am J Cardiol. 2019 Aug 1;124(3):373-380. doi: 10.1016/j.amjcard.2019.05.010. Epub 2019 May 9.


Cangrelor versus Ticagrelor in Patients Treated with Primary Percutaneous Coronary Intervention: Impact on Platelet Activity, Myocardial Microvascular Function and Infarct Size: A Randomized Controlled Trial.

Ubaid S, Ford TJ, Berry C, Murray HM, Wrigley B, Khan N, Thomas MR, Armesilla AL, Townend JN, Khogali SS, Munir S, Martins J, Hothi SS, McAlindon EJ, Cotton JM.

Thromb Haemost. 2019 Jul;119(7):1171-1181. doi: 10.1055/s-0039-1688789. Epub 2019 May 26.


Vive les Differences!-A case for optimism in the treatment of patients with heart failure and preserved ejection fraction?

Law JP, Pickup L, Townend JN, Ferro CJ.

Int J Clin Pract. 2019 Jun;73(6):e13307. doi: 10.1111/ijcp.13307. No abstract available.


Chronic kidney disease as a cardiovascular risk factor: lessons from kidney donors.

Price AM, Edwards NC, Hayer MK, Moody WE, Steeds RP, Ferro CJ, Townend JN.

J Am Soc Hypertens. 2018 Jul;12(7):497-505.e4. doi: 10.1016/j.jash.2018.04.010. Epub 2018 May 9. Review.


Diffuse Myocardial Interstitial Fibrosis and Dysfunction in Early Chronic Kidney Disease.

Hayer MK, Price AM, Liu B, Baig S, Ferro CJ, Townend JN, Steeds RP, Edwards NC.

Am J Cardiol. 2018 Mar 1;121(5):656-660. doi: 10.1016/j.amjcard.2017.11.041. Epub 2017 Dec 11.


Results of Serial Myocardial Perfusion Imaging in End-Stage Renal Disease.

Moody WE, Lin ELS, Thomson LE, Berman DS, Edwards NC, Holloway B, Ferro CJ, Townend JN, Steeds RP; Birmingham Cardio-Renal Group.

Am J Cardiol. 2018 Mar 1;121(5):661-667. doi: 10.1016/j.amjcard.2017.11.038. Epub 2017 Dec 11.


Novel United Kingdom prognostic model for 30-day mortality following transcatheter aortic valve implantation.

Martin GP, Sperrin M, Ludman PF, de Belder MA, Redwood SR, Townend JN, Gunning M, Moat NE, Banning AP, Buchan I, Mamas MA.

Heart. 2018 Jul;104(13):1109-1116. doi: 10.1136/heartjnl-2017-312489. Epub 2017 Dec 7.


A feasibility study of transaxillary TAVI with the lotus valve.

Doshi SN, George S, Kwok CS, Mechery A, Mamas M, Ludman PF, Townend JN, Bhabra M.

Catheter Cardiovasc Interv. 2018 Sep 1;92(3):542-549. doi: 10.1002/ccd.27409. Epub 2017 Nov 11.


Premature coronary artery disease and early stage chronic kidney disease.

Price AM, Ferro CJ, Hayer MK, Steeds RP, Edwards NC, Townend JN.

QJM. 2018 Oct 1;111(10):683-686. doi: 10.1093/qjmed/hcx179. Review.


A randomized, multicenter, open-label, blinded end point trial comparing the effects of spironolactone to chlorthalidone on left ventricular mass in patients with early-stage chronic kidney disease: Rationale and design of the SPIRO-CKD trial.

Hayer MK, Edwards NC, Slinn G, Moody WE, Steeds RP, Ferro CJ, Price AM, Andujar C, Dutton M, Webster R, Webb DJ, Semple S, MacIntyre I, Melville V, Wilkinson IB, Hiemstra TF, Wheeler DC, Herrey A, Grant M, Mehta S, Ives N, Townend JN.

Am Heart J. 2017 Sep;191:37-46. doi: 10.1016/j.ahj.2017.05.008. Epub 2017 May 24.


Dialysis Following Transcatheter Aortic Valve Replacement: Risk Factors and Outcomes: An Analysis From the UK TAVI (Transcatheter Aortic Valve Implantation) Registry.

Ferro CJ, Law JP, Doshi SN, de Belder M, Moat N, Mamas M, Hildick-Smith D, Ludman P, Townend JN; UK TAVI Steering Group and the National Institute for Cardiovascular Outcomes Research.

JACC Cardiovasc Interv. 2017 Oct 23;10(20):2040-2047. doi: 10.1016/j.jcin.2017.05.020. Epub 2017 Aug 2.


A review of rate control in atrial fibrillation, and the rationale and protocol for the RATE-AF trial.

Kotecha D, Calvert M, Deeks JJ, Griffith M, Kirchhof P, Lip GY, Mehta S, Slinn G, Stanbury M, Steeds RP, Townend JN.

BMJ Open. 2017 Jul 20;7(7):e015099. doi: 10.1136/bmjopen-2016-015099.


Transcatheter Aortic Valve Implantation With or Without Percutaneous Coronary Artery Revascularization Strategy: A Systematic Review and Meta-Analysis.

Kotronias RA, Kwok CS, George S, Capodanno D, Ludman PF, Townend JN, Doshi SN, Khogali SS, Généreux P, Herrmann HC, Mamas MA, Bagur R.

J Am Heart Assoc. 2017 Jun 27;6(6). pii: e005960. doi: 10.1161/JAHA.117.005960. Review.


Assessing flow limitation in patients with stable coronary artery disease.

Townend JN, Ludman PF, Doshi SN, Khan H, Calvert PA.

BMJ. 2016 Oct 20;355:i5534. doi: 10.1136/bmj.i5534. No abstract available.


Re: assessment of myocardial fibrosis with T1 mapping MRI.

Hayer MK, Ferro CJ, Townend JN, Steeds RP, Edwards NC.

Clin Radiol. 2016 Dec;71(12):1309-1310. doi: 10.1016/j.crad.2016.09.005. Epub 2016 Oct 10. No abstract available.


SPRINTing towards trials of blood pressure reduction to reduce CKD progression?

Moody WE, Ferro CJ, Townend JN.

Eur Heart J Qual Care Clin Outcomes. 2016 Oct 1;2(4):229-230. doi: 10.1093/ehjqcco/qcw035. No abstract available.


Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis.

Currie G, Taylor AH, Fujita T, Ohtsu H, Lindhardt M, Rossing P, Boesby L, Edwards NC, Ferro CJ, Townend JN, van den Meiracker AH, Saklayen MG, Oveisi S, Jardine AG, Delles C, Preiss DJ, Mark PB.

BMC Nephrol. 2016 Sep 8;17(1):127. doi: 10.1186/s12882-016-0337-0. Review.


Prognostic Utility of Calcium Scoring as an Adjunct to Stress Myocardial Perfusion Scintigraphy in End-Stage Renal Disease.

Moody WE, Lin EL, Stoodley M, McNulty D, Thomson LE, Berman DS, Edwards NC, Holloway B, Ferro CJ, Townend JN, Steeds RP; Birmingham Cardio-Renal Group.

Am J Cardiol. 2016 May 1;117(9):1387-96. doi: 10.1016/j.amjcard.2016.02.003. Epub 2016 Feb 17.


Results and lessons from the Spironolactone To Prevent Cardiovascular Events in Early Stage Chronic Kidney Disease (STOP-CKD) randomised controlled trial.

Ng KP, Jain P, Gill PS, Heer G, Townend JN, Freemantle N, Greenfield S, McManus RJ, Ferro CJ.

BMJ Open. 2016 Feb 25;6(2):e010519. doi: 10.1136/bmjopen-2015-010519.


Cardiovascular Effects of Unilateral Nephrectomy in Living Kidney Donors.

Moody WE, Ferro CJ, Edwards NC, Chue CD, Lin EL, Taylor RJ, Cockwell P, Steeds RP, Townend JN; CRIB-Donor Study Investigators.

Hypertension. 2016 Feb;67(2):368-77. doi: 10.1161/HYPERTENSIONAHA.115.06608.


Mechanical effects of left ventricular midwall fibrosis in non-ischemic cardiomyopathy.

Taylor RJ, Umar F, Lin EL, Ahmed A, Moody WE, Mazur W, Stegemann B, Townend JN, Steeds RP, Leyva F.

J Cardiovasc Magn Reson. 2016 Jan 5;18:1. doi: 10.1186/s12968-015-0221-2.


Spontaneous Coronary Artery Dissection/Intramural Haematoma in Young Women with ST-Elevation Myocardial Infarction: "It Is Not Always a Plaque Rupture Event".

Kassimis G, Manolis A, Townend JN.

Case Rep Cardiol. 2015;2015:597234. doi: 10.1155/2015/597234. Epub 2015 Oct 21.


Caveolin-1 single-nucleotide polymorphism and arterial stiffness in non-dialysis chronic kidney disease.

Chand S, Edwards NC, Chue CD, Jesky M, Stringer S, Simmonds MJ, Duff CE, Cockwell P, Harper L, Steeds RP, Townend JN, Ferro CJ, Borrows R.

Nephrol Dial Transplant. 2016 Jul;31(7):1140-4. doi: 10.1093/ndt/gfv350. Epub 2015 Oct 3.


Successful treatment of a radial artery pseudoaneurysm in an octogenarian.

Mohamed MO, Saif M, Townend JN, Khan SQ.

BMJ Case Rep. 2015 Aug 4;2015. pii: bcr2015211513. doi: 10.1136/bcr-2015-211513.


Acute Care QUAliTy in chronic Kidney disease (ACQUATIK): a prospective cohort study exploring outcomes of patients with chronic kidney disease.

Arnold JJ, Hayer M, Sharif A, Begaj I, Tabriez M, Bagnall D, Ray D, Hoye C, Nazir M, Dutton M, Fifer L, Kirkham K, Sims D, Townend JN, Gill PS, Dasgupta I, Cockwell P, Ferro CJ.

BMJ Open. 2015 May 3;5(4):e006987. doi: 10.1136/bmjopen-2014-006987.


Cardiovascular actions of mineralocorticoid receptor antagonists in patients with chronic kidney disease: A systematic review and meta-analysis of randomized trials.

Ng KP, Arnold J, Sharif A, Gill P, Townend JN, Ferro CJ.

J Renin Angiotensin Aldosterone Syst. 2015 Sep;16(3):599-613. doi: 10.1177/1470320315575849. Epub 2015 Mar 17. Review.


Diffuse interstitial fibrosis and myocardial dysfunction in early chronic kidney disease.

Edwards NC, Moody WE, Yuan M, Hayer MK, Ferro CJ, Townend JN, Steeds RP.

Am J Cardiol. 2015 May 1;115(9):1311-7. doi: 10.1016/j.amjcard.2015.02.015. Epub 2015 Feb 12.


Coronary Artery Calcium Assessment in CKD: Utility in Cardiovascular Disease Risk Assessment and Treatment?

Bashir A, Moody WE, Edwards NC, Ferro CJ, Townend JN, Steeds RP.

Am J Kidney Dis. 2015 Jun;65(6):937-48. doi: 10.1053/j.ajkd.2015.01.012. Epub 2015 Mar 6. Review.


Myocardial strain measurement with feature-tracking cardiovascular magnetic resonance: normal values.

Taylor RJ, Moody WE, Umar F, Edwards NC, Taylor TJ, Stegemann B, Townend JN, Hor KN, Steeds RP, Mazur W, Leyva F.

Eur Heart J Cardiovasc Imaging. 2015 Aug;16(8):871-81. doi: 10.1093/ehjci/jev006. Epub 2015 Feb 23.


Variability in cardiac MR measurement of left ventricular ejection fraction, volumes and mass in healthy adults: defining a significant change at 1 year.

Moody WE, Edwards NC, Chue CD, Taylor RJ, Ferro CJ, Townend JN, Steeds RP.

Br J Radiol. 2015 May;88(1049):20140831. doi: 10.1259/bjr.20140831. Epub 2015 Feb 24.


Endothelial nitric oxide synthase single nucleotide polymorphism and left ventricular function in early chronic kidney disease.

Chand S, Chue CD, Edwards NC, Hodson J, Simmonds MJ, Hamilton A, Gough SC, Harper L, Steeds RP, Townend JN, Ferro CJ, Borrows R.

PLoS One. 2015 Jan 22;10(1):e0116160. doi: 10.1371/journal.pone.0116160. eCollection 2015.


Impact of renal function on survival after transcatheter aortic valve implantation (TAVI): an analysis of the UK TAVI registry.

Ferro CJ, Chue CD, de Belder MA, Moat N, Wendler O, Trivedi U, Ludman P, Townend JN; UK TAVI Steering Group; National Institute for Cardiovascular Outcomes Research.

Heart. 2015 Apr;101(7):546-52. doi: 10.1136/heartjnl-2014-307041. Epub 2015 Jan 12.


Central blood pressure in chronic kidney disease: latest evidence and clinical relevance.

Yuan M, Moody WE, Townend JN.

Curr Hypertens Rev. 2014;10(2):99-106. Review.


Percutaneous Mechanical Ventricular Support in Acute Cardiac Care: A UK Quaternary Centre Experience Using 2.5L, 3.8L and 5.0L Impella Catheters.

Venugopal V, Spiro J, Zaphiriou A, Khan S, Townend JN, Ludman PF, Doshi SN.

Cardiol Ther. 2015 Jun;4(1):47-58. doi: 10.1007/s40119-014-0033-8. Epub 2014 Dec 17.


Automated cardiopulmonary resuscitation using a load-distributing band external cardiac support device for in-hospital cardiac arrest: a single centre experience of AutoPulse-CPR.

Spiro JR, White S, Quinn N, Gubran CJ, Ludman PF, Townend JN, Doshi SN.

Int J Cardiol. 2015 Feb 1;180:7-14. doi: 10.1016/j.ijcard.2014.11.109. Epub 2014 Nov 18.


Phosphate: are we squandering a scarce commodity?

Ferro CJ, Ritz E, Townend JN.

Nephrol Dial Transplant. 2015 Feb;30(2):163-8. doi: 10.1093/ndt/gfu295. Epub 2014 Sep 17.


Quantification of left ventricular interstitial fibrosis in asymptomatic chronic primary degenerative mitral regurgitation.

Edwards NC, Moody WE, Yuan M, Weale P, Neal D, Townend JN, Steeds RP.

Circ Cardiovasc Imaging. 2014 Nov;7(6):946-53. doi: 10.1161/CIRCIMAGING.114.002397. Epub 2014 Aug 19.


The EARNEST study: interarm blood pressure differences should also be recorded.

Moody WE, Ferro CJ, Townend JN; EARNEST Study Investigators.

Am Heart J. 2014 Aug;168(2):e9. doi: 10.1016/j.ahj.2014.05.006. Epub 2014 May 17. No abstract available.


Defining the natural history of uremic cardiomyopathy in chronic kidney disease: the role of cardiovascular magnetic resonance.

Edwards NC, Moody WE, Chue CD, Ferro CJ, Townend JN, Steeds RP.

JACC Cardiovasc Imaging. 2014 Jul;7(7):703-14. doi: 10.1016/j.jcmg.2013.09.025.


Spironolactone to prevent cardiovascular events in early-stage chronic kidney disease (STOP-CKD): study protocol for a randomized controlled pilot trial.

Ng KP, Jain P, Heer G, Redman V, Chagoury OL, Dowswell G, Greenfield S, Freemantle N, Townend JN, Gill PS, McManus RJ, Ferro CJ.

Trials. 2014 May 6;15:158. doi: 10.1186/1745-6215-15-158.

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