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Items: 1 to 50 of 484

1.

Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel.

Alves-Lopes R, Neves KB, Anagnostopoulou A, Rios FJ, Lacchini S, Montezano AC, Touyz RM.

Hypertension. 2019 Nov 18:HYPERTENSIONAHA11913861. doi: 10.1161/HYPERTENSIONAHA.119.13861. [Epub ahead of print]

PMID:
31735084
2.

Analysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease.

Bernal J, Valdés-Hernández MDC, Escudero J, Viksne L, Heye AK, Armitage PA, Makin S, Touyz RM, Wardlaw JM.

Magn Reson Imaging. 2019 Nov 13. pii: S0730-725X(19)30496-5. doi: 10.1016/j.mri.2019.11.001. [Epub ahead of print]

3.

One-Year Outcomes of Angina Management Guided by Invasive Coronary Function Testing (CorMicA).

Ford TJ, Stanley B, Sidik N, Good R, Rocchiccioli P, McEntegart M, Watkins S, Eteiba H, Shaukat A, Lindsay M, Robertson K, Hood S, McGeoch R, McDade R, Yii E, McCartney P, Corcoran D, Collison D, Rush C, Sattar N, McConnachie A, Touyz RM, Oldroyd KG, Berry C.

JACC Cardiovasc Interv. 2019 Nov 8. pii: S1936-8798(19)32366-0. doi: 10.1016/j.jcin.2019.11.001. [Epub ahead of print]

4.

Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures.

Kelleher J, Dickinson A, Cain S, Hu Y, Bates N, Harvey A, Ren J, Zhang W, Moreton FC, Muir KW, Ward C, Touyz RM, Sharma P, Xu Q, Kimber SJ, Wang T.

Stem Cell Reports. 2019 Nov 12;13(5):817-831. doi: 10.1016/j.stemcr.2019.10.004. Epub 2019 Oct 31.

5.

Gender-Affirming Hormone Therapy, Vascular Health and Cardiovascular Disease in Transgender Adults.

Connelly PJ, Marie Freel E, Perry C, Ewan J, Touyz RM, Currie G, Delles C.

Hypertension. 2019 Dec;74(6):1266-1274. doi: 10.1161/HYPERTENSIONAHA.119.13080. Epub 2019 Oct 28.

PMID:
31656099
6.

ER stress and Rho kinase activation underlie the vasculopathy of CADASIL.

Neves KB, Harvey AP, Moreton F, Montezano AC, Rios FJ, Alves-Lopes R, Nguyen Dinh Cat A, Rocchiccioli P, Delles C, Joutel A, Muir K, Touyz RM.

JCI Insight. 2019 Oct 24. pii: 131344. doi: 10.1172/jci.insight.131344. [Epub ahead of print]

7.

Selective ETA versus dual ETA/B receptor blockade for the prevention of sunitinib-induced hypertension and albuminuria in WKY rats.

Mirabito Colafella KM, Neves KB, Montezano AC, Garrelds IM, van Veghel R, de Vries R, Uijl E, Baelde HJ, van den Meiracker AH, Touyz RM, Danser AHJ, Versmissen J.

Cardiovasc Res. 2019 Oct 8. pii: cvz260. doi: 10.1093/cvr/cvz260. [Epub ahead of print]

PMID:
31593221
8.

Progressive Hypertension and Severe Left Ventricular Outflow Tract Obstruction.

Cameron AC, Lang NN, Dominiczak AF, Jennings GLR, Batlle D, Bursztyn M, Chugh AR, Floras JS, Taler SJ, Touyz RM, Delles C.

Hypertension. 2019 Dec;74(6):1216-1225. doi: 10.1161/HYPERTENSIONAHA.119.13343. Epub 2019 Oct 7. No abstract available.

PMID:
31587571
9.

Cardiovascular care of patients with stroke and high risk of stroke: The need for interdisciplinary action: A consensus report from the European Society of Cardiology Cardiovascular Round Table.

Doehner W, Mazighi M, Hofmann BM, Lautsch D, Hindricks G, Bohula EA, Byrne RA, Camm AJ, Casadei B, Caso V, Cognard C, Diener HC, Endres M, Goldstein P, Halliday A, Hopewell JC, Jovanovic DR, Kobayashi A, Kostrubiec M, Krajina A, Landmesser U, Markus HS, Ntaios G, Pezzella FR, Ribo M, Rosano GM, Rubiera M, Sharma M, Touyz RM, Widimsky P.

Eur J Prev Cardiol. 2019 Sep 30:2047487319873460. doi: 10.1177/2047487319873460. [Epub ahead of print]

PMID:
31569966
10.

T Cells Are Dominant Population in Human Abdominal Aortic Aneurysms and Their Infiltration in the Perivascular Tissue Correlates With Disease Severity.

Sagan A, Mikolajczyk TP, Mrowiecki W, MacRitchie N, Daly K, Meldrum A, Migliarino S, Delles C, Urbanski K, Filip G, Kapelak B, Maffia P, Touyz R, Guzik TJ.

Front Immunol. 2019 Sep 4;10:1979. doi: 10.3389/fimmu.2019.01979. eCollection 2019.

11.

Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure.

Arendse LB, Danser AHJ, Poglitsch M, Touyz RM, Burnett JC Jr, Llorens-Cortes C, Ehlers MR, Sturrock ED.

Pharmacol Rev. 2019 Oct;71(4):539-570. doi: 10.1124/pr.118.017129. Review.

12.

Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland.

Cacciottolo TM, Perikari A, van der Klaauw A, Henning E, Stadler LKJ, Keogh J, Farooqi IS, Tenin G, Keavney B, Ryan E, Budd R, Bewley M, Coelho P, Rumsey W, Sanchez Y, McCafferty J, Dockrell D, Walmsley S, Whyte M, Liu Y, Choy MK, Tenin G, Abraham S, Black G, Keavney B, Ford T, Stanley B, Good R, Rocchiccioli P, McEntegart M, Watkins S, Eteiba H, Shaukat A, Lindsay M, Robertson K, Hood S, McGeoch R, McDade R, Sidik N, McCartney P, Corcoran D, Collison D, Rush C, McConnachie A, Touyz R, Oldroyd K, Berry C, Gazdagh G, Diver L, Marshall J, McGowan R, Ahmed F; DDD Study, Tobias E, Curtis E, Parsons C, Maslin K, D'Angelo S, Moon R, Crozier S, Gossiel F, Bishop N, Kennedy S, Papageorghiou A, Fraser R, Gandhi S, Prentice A, Inskip H, Godfrey K, Schoenmakers I, Javaid MK, Eastell R, Cooper C, Harvey N, Watt ER, Howden A, Mirchandani A, Coelho P, Hukelmann JL, Sadiku P, Plant TM, Cantrell DA, Whyte MKB, Walmsley SR, Mordi I, Forteath C, Wong A, Mohan M, Palmer C, Doney A, Rena G, Lang C, Gray EH, Azarian S, Riva A, Edwards H, McPhail MJW, Williams R, Chokshi S, Patel VC, Edwards LA, Page D, Miossec M, Williams S, Monaghan R, Fotiou E; CHANGE Study Collaborators, CheartED Study Collaborators, Santibanez-Koref M, Keavney B, Badat M, Mettananda S, Hua P, Schwessinger R, Hughes J, Higgs D, Davies J.

QJM. 2019 Sep 1;112(9):724-729. doi: 10.1093/qjmed/hcz175. No abstract available.

PMID:
31505685
13.

Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation.

Cameron AC, Welsh P, Neves KB, Newby DE, Touyz RM, Lang NN.

J Hypertens. 2019 Aug 19. doi: 10.1097/HJH.0000000000002230. [Epub ahead of print]

PMID:
31449168
14.

Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.

Rios FJ, Zou ZG, Harvey AP, Harvey KY, Nosalski R, Anyfanti P, Camargo LL, Lacchini S, Ryazanov AG, Ryazanova L, McGrath S, Guzik TJ, Goodyear CS, Montezano AC, Touyz RM.

Cardiovasc Res. 2019 Jun 28. pii: cvz164. doi: 10.1093/cvr/cvz164. [Epub ahead of print]

PMID:
31250885
15.

Extracellular Vesicles as Biomarkers and Biovectors in Primary Aldosteronism.

Neves KB, Touyz RM.

Hypertension. 2019 Aug;74(2):250-252. doi: 10.1161/HYPERTENSIONAHA.119.13088. Epub 2019 Jun 24. No abstract available.

PMID:
31230536
16.

Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse.

Jha JC, Dai A, Holterman CE, Cooper ME, Touyz RM, Kennedy CR, Jandeleit-Dahm KAM.

Diabetologia. 2019 Sep;62(9):1712-1726. doi: 10.1007/s00125-019-4924-z. Epub 2019 Jun 20.

PMID:
31222503
17.

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension.

Beaney T, Burrell LM, Castillo RR, Charchar FJ, Cro S, Damasceno A, Kruger R, Nilsson PM, Prabhakaran D, Ramirez AJ, Schlaich MP, Schutte AE, Tomaszewski M, Touyz R, Wang JG, Weber MA, Poulter NR; MMM Investigators .

Eur Heart J. 2019 Jul 1;40(25):2006-2017. doi: 10.1093/eurheartj/ehz300. Erratum in: Eur Heart J. 2019 Oct 1;40(37):3109.

18.

Hypertension Guidelines: Effect of Blood Pressure Targets.

Touyz RM.

Can J Cardiol. 2019 May;35(5):564-569. doi: 10.1016/j.cjca.2019.03.014. Epub 2019 Mar 21.

PMID:
31030859
19.

TRPM7, Magnesium, and Signaling.

Zou ZG, Rios FJ, Montezano AC, Touyz RM.

Int J Mol Sci. 2019 Apr 16;20(8). pii: E1877. doi: 10.3390/ijms20081877. Review.

20.

Muscarinic Receptor Type-3 in Hypertension and Cholinergic-Adrenergic Crosstalk: Genetic Insights and Potential for New Antihypertensive Targets.

Alves-Lopes R, Neves KB, Touyz RM.

Can J Cardiol. 2019 May;35(5):555-557. doi: 10.1016/j.cjca.2019.02.003. Epub 2019 Feb 13. No abstract available.

21.

Response to the letter regarding the hypothesis paper "Much ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localised oedema".

Rossitto G, Touyz RM, Petrie MC, Delles C.

Clin Sci (Lond). 2019 Mar 19;133(6):761. doi: 10.1042/CS20190154. Print 2019 Mar 29.

PMID:
30890653
22.

Animal Models of Hypertension: A Scientific Statement From the American Heart Association.

Lerman LO, Kurtz TW, Touyz RM, Ellison DH, Chade AR, Crowley SD, Mattson DL, Mullins JJ, Osborn J, Eirin A, Reckelhoff JF, Iadecola C, Coffman TM.

Hypertension. 2019 Jun;73(6):e87-e120. doi: 10.1161/HYP.0000000000000090. Review.

23.

Microglia, the Missing Link in the Brain-Gut-Hypertension Axis.

Touyz RM, Camargo LL.

Circ Res. 2019 Mar;124(5):671-673. doi: 10.1161/CIRCRESAHA.119.314718. No abstract available.

PMID:
30817265
24.

NOX5: Molecular biology and pathophysiology.

Touyz RM, Anagnostopoulou A, Rios F, Montezano AC, Camargo LL.

Exp Physiol. 2019 May;104(5):605-616. doi: 10.1113/EP086204. Epub 2019 Mar 18.

25.

Microparticles from vascular endothelial growth factor pathway inhibitor-treated cancer patients mediate endothelial cell injury.

Neves KB, Rios FJ, Jones R, Evans TRJ, Montezano AC, Touyz RM.

Cardiovasc Res. 2019 Apr 15;115(5):978-988. doi: 10.1093/cvr/cvz021.

26.

Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress.

Bruder-Nascimento T, Callera GE, Montezano AC, Belin de Chantemele EJ, Tostes RC, Touyz RM.

Life Sci. 2019 Mar 15;221:29-34. doi: 10.1016/j.lfs.2019.01.043. Epub 2019 Feb 2.

27.

Small-Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need, and Future Directions.

Berry C, Sidik N, Pereira AC, Ford TJ, Touyz RM, Kaski JC, Hainsworth AH.

J Am Heart Assoc. 2019 Feb 5;8(3):e011104. doi: 10.1161/JAHA.118.011104. No abstract available.

28.

Rationale and design of the Coronary Microvascular Angina Cardiac Magnetic Resonance Imaging (CorCMR) diagnostic study: the CorMicA CMR sub-study.

Corcoran D, Ford TJ, Hsu LY, Chiribiri A, Orchard V, Mangion K, McEntegart M, Rocchiccioli P, Watkins S, Good R, Brooksbank K, Padmanabhan S, Sattar N, McConnachie A, Oldroyd KG, Touyz RM, Arai A, Berry C.

Open Heart. 2018 Dec 30;5(2):e000924. doi: 10.1136/openhrt-2018-000924. eCollection 2018.

29.

Aldosterone and Ion Channels.

Valinsky WC, Touyz RM, Shrier A.

Vitam Horm. 2019;109:105-131. doi: 10.1016/bs.vh.2018.10.004. Epub 2018 Dec 1. Review.

PMID:
30678852
30.

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV.

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222.

31.

Much Ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localized oedema.

Rossitto G, Touyz RM, Petrie MC, Delles C.

Clin Sci (Lond). 2018 Dec 13;132(24):2609-2613. doi: 10.1042/CS20180575. Print 2018 Dec 21. Review.

32.

PARP-1 (Poly[ADP-Ribose] Polymerase-1).

Alves-Lopes R, Touyz RM.

Hypertension. 2018 Nov;72(5):1087-1089. doi: 10.1161/HYPERTENSIONAHA.118.11830. No abstract available.

33.

The Meaning of Mas.

Bader M, Alenina N, Young D, Santos RAS, Touyz RM.

Hypertension. 2018 Nov;72(5):1072-1075. doi: 10.1161/HYPERTENSIONAHA.118.10918. Review. No abstract available.

34.

Vascular Biology of Superoxide-Generating NADPH Oxidase 5-Implications in Hypertension and Cardiovascular Disease.

Touyz RM, Anagnostopoulou A, Camargo LL, Rios FJ, Montezano AC.

Antioxid Redox Signal. 2019 Mar 1;30(7):1027-1040. doi: 10.1089/ars.2018.7583. Epub 2018 Nov 15.

35.

Stratified Medical Therapy Using Invasive Coronary Function Testing in Angina: The CorMicA Trial.

Ford TJ, Stanley B, Good R, Rocchiccioli P, McEntegart M, Watkins S, Eteiba H, Shaukat A, Lindsay M, Robertson K, Hood S, McGeoch R, McDade R, Yii E, Sidik N, McCartney P, Corcoran D, Collison D, Rush C, McConnachie A, Touyz RM, Oldroyd KG, Berry C.

J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2841-2855. doi: 10.1016/j.jacc.2018.09.006. Epub 2018 Sep 25.

PMID:
30266608
36.

Toxicity of cancer therapy: what the cardiologist needs to know about angiogenesis inhibitors.

Dobbin SJH, Cameron AC, Petrie MC, Jones RJ, Touyz RM, Lang NN.

Heart. 2018 Dec;104(24):1995-2002. doi: 10.1136/heartjnl-2018-313726. Epub 2018 Sep 18. Review.

37.

Chemerin receptor blockade improves vascular function in diabetic obese mice via redox-sensitive and Akt-dependent pathways.

Neves KB, Nguyen Dinh Cat A, Alves-Lopes R, Harvey KY, Costa RMD, Lobato NS, Montezano AC, Oliveira AM, Touyz RM, Tostes RC.

Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1851-H1860. doi: 10.1152/ajpheart.00285.2018. Epub 2018 Sep 14.

PMID:
30216119
38.

Cardiotoxicity with vascular endothelial growth factor inhibitor therapy.

Touyz RM, Herrmann J.

NPJ Precis Oncol. 2018 May 8;2:13. doi: 10.1038/s41698-018-0056-z. eCollection 2018. Review.

39.

Systemic microvascular dysfunction in microvascular and vasospastic angina.

Ford TJ, Rocchiccioli P, Good R, McEntegart M, Eteiba H, Watkins S, Shaukat A, Lindsay M, Robertson K, Hood S, Yii E, Sidik N, Harvey A, Montezano AC, Beattie E, Haddow L, Oldroyd KG, Touyz RM, Berry C.

Eur Heart J. 2018 Dec 7;39(46):4086-4097. doi: 10.1093/eurheartj/ehy529.

40.

Upregulation of Nrf2 and Decreased Redox Signaling Contribute to Renoprotective Effects of Chemerin Receptor Blockade in Diabetic Mice.

Neves KB, Montezano AC, Alves-Lopes R, Bruder-Nascimento T, Costa RM, Costa RS, Touyz RM, Tostes RC.

Int J Mol Sci. 2018 Aug 19;19(8). pii: E2454. doi: 10.3390/ijms19082454.

41.

Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study.

Kerr DMI, Brooksbank KJM, Taylor RG, Pinel K, Rios FJ, Touyz RM, Delles C.

J Hypertens. 2019 Jan;37(1):154-166. doi: 10.1097/HJH.0000000000001890.

PMID:
30063637
42.

Are the American Heart Association/American College of Cardiology High Blood Pressure Guidelines Fit for Global Purpose?: Thoughts From the International Society of Hypertension.

Poulter NR, Castillo R, Charchar FJ, Schlaich MP, Schutte AE, Tomaszewski M, Touyz RM, Wang JG.

Hypertension. 2018 Aug;72(2):260-262. doi: 10.1161/HYPERTENSIONAHA.118.11452. Epub 2018 Jul 2. Review. No abstract available.

43.

NADPH Oxidase 5 Is a Pro-Contractile Nox Isoform and a Point of Cross-Talk for Calcium and Redox Signaling-Implications in Vascular Function.

Montezano AC, De Lucca Camargo L, Persson P, Rios FJ, Harvey AP, Anagnostopoulou A, Palacios R, Gandara ACP, Alves-Lopes R, Neves KB, Dulak-Lis M, Holterman CE, de Oliveira PL, Graham D, Kennedy C, Touyz RM.

J Am Heart Assoc. 2018 Jun 15;7(12). pii: e009388. doi: 10.1161/JAHA.118.009388.

44.

Dr Giacomo Rossitto interviews Professor Rhian Touyz, on the translational applications of vascular smooth muscle cell biology in cardiovascular disease.

Rossitto G, Touyz R.

Cardiovasc Res. 2018 May 1;114(6):e43. doi: 10.1093/cvr/cvy081. No abstract available.

PMID:
29897497
45.

Vascular Nox (NADPH Oxidase) Compartmentalization, Protein Hyperoxidation, and Endoplasmic Reticulum Stress Response in Hypertension.

Camargo LL, Harvey AP, Rios FJ, Tsiropoulou S, Da Silva RNO, Cao Z, Graham D, McMaster C, Burchmore RJ, Hartley RC, Bulleid N, Montezano AC, Touyz RM.

Hypertension. 2018 Jul;72(1):235-246. doi: 10.1161/HYPERTENSIONAHA.118.10824. Epub 2018 May 29.

46.

Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial.

Ford TJ, Corcoran D, Oldroyd KG, McEntegart M, Rocchiccioli P, Watkins S, Brooksbank K, Padmanabhan S, Sattar N, Briggs A, McConnachie A, Touyz R, Berry C.

Am Heart J. 2018 Jul;201:86-94. doi: 10.1016/j.ahj.2018.03.010. Epub 2018 Apr 3. Review.

47.

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM.

Clin Sci (Lond). 2018 Apr 30;132(8):851-868. doi: 10.1042/CS20171620. Print 2018 Apr 30.

48.

Vascular toxicities with VEGF inhibitor therapies-focus on hypertension and arterial thrombotic events.

Touyz RM, Herrmann SMS, Herrmann J.

J Am Soc Hypertens. 2018 Jun;12(6):409-425. doi: 10.1016/j.jash.2018.03.008. Epub 2018 Mar 21. Review.

49.

Resistant Hypertension: Trials and Tribulations.

George MJ, Marks DJB, Rezk T, Breckenridge R, Sofat R, Martin J, MacAllister R, Touyz RM, Staessen JA, Bursztyn M, Lappin D, Barigou M, Hingorani A.

Hypertension. 2018 May;71(5):772-780. doi: 10.1161/HYPERTENSIONAHA.118.10864. Epub 2018 Apr 2. Review. No abstract available.

PMID:
29610269
50.

Case of Severe Hypertension and Nephrotic Range Proteinuria.

Bursztyn M, Touyz RM, Laffer CL, Carey RM, Dominiczak AF.

Hypertension. 2018 Jun;71(6):956-961. doi: 10.1161/HYPERTENSIONAHA.118.11045. Epub 2018 Apr 2. No abstract available.

PMID:
29610267

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