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Commutability of proficiency testing material containing amitriptyline and nortriptyline: A study within the framework of the Dutch Calibration 2.000 project.

Robijns K, Boone NW, Jansen RTP, Kuypers AWHM, Neef C, Touw DJ.

Clin Chim Acta. 2019 Jul 30;498:6-10. doi: 10.1016/j.cca.2019.07.036. [Epub ahead of print]


Performance of a web-based application measuring spot quality in dried blood spot sampling.

Veenhof H, Koster RA, Brinkman R, Senturk E, Bakker SJL, Berger SP, Akkerman OW, Touw DJ, Alffenaar JC.

Clin Chem Lab Med. 2019 Aug 2. pii: /j/cclm.ahead-of-print/cclm-2019-0437/cclm-2019-0437.xml. doi: 10.1515/cclm-2019-0437. [Epub ahead of print]


In vitro evaluation of an intravenous microdialysis catheter for therapeutic drug monitoring of gentamicin and vancomycin.

van der Mast JE, Nijsten MW, Alffenaar JC, Touw DJ, Bult W.

Pharmacol Res Perspect. 2019 Jun 26;7(4):e00483. doi: 10.1002/prp2.483. eCollection 2019 Aug.


Pharmacokinetic/pharmacodynamic analysis of weight- and height-scaled tobramycin dosage regimens for patients with cystic fibrosis.

Alghanem SS, Touw DJ, Thomson AH.

J Antimicrob Chemother. 2019 Aug 1;74(8):2311-2317. doi: 10.1093/jac/dkz192.


Official International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot-Based Methods for Therapeutic Drug Monitoring.

Capiau S, Veenhof H, Koster RA, Bergqvist Y, Boettcher M, Halmingh O, Keevil BG, Koch BCP, Linden R, Pistos C, Stolk LM, Touw DJ, Stove CP, Alffenaar JC.

Ther Drug Monit. 2019 Aug;41(4):409-430. doi: 10.1097/FTD.0000000000000643.


Urinary Ethyl Glucuronide Can Be Used as a Biomarker of Habitual Alcohol Consumption in the General Population.

van de Luitgaarden IAT, Beulens JWJ, Schrieks IC, Kieneker LM, Touw DJ, van Ballegooijen AJ, van Oort S, Grobbee DE, Bakker SJL.

J Nutr. 2019 Jul 3. pii: nxz146. doi: 10.1093/jn/nxz146. [Epub ahead of print]


Quality Assessment of Dried Blood Spots from Tuberculosis Patients from Four Countries.

Zuur MA, Veenhof H, Aleksa A, Boveneind-Vrubleuskaya NV', Darmawan E, Hasnain MG, Heysell SK, Jongedijk EM, Koster RA, Magis-Escurra C, Martinez N, Molinas G, Mondal D, Mulyani UA, Perwitasari DA, Tsivunchyk A, Touw DJ, Alffenaar JC.

Ther Drug Monit. 2019 Jun 4. doi: 10.1097/FTD.0000000000000659. [Epub ahead of print]


Grand Round: Reversible impaired methotrexate clearance after platinum-based chemotherapy for osteosarcoma.

Oude Munnink TH, van der Meer A, de Haan JJ, Touw DJ, van Kruchten M.

Ther Drug Monit. 2019 Jun 4. doi: 10.1097/FTD.0000000000000662. [Epub ahead of print]


Colistin methanesulfonate infusion solutions are stable over time and suitable for home administration.

Post TE, Kamerling IMC, van Rossen RCJM, Burggraaf J, Stevens J, Dijkmans AC, Heijerman HGM, Touw DJ, van Velzen AJ, Wilms EB.

Eur J Hosp Pharm. 2018 Nov;25(6):337-339. doi: 10.1136/ejhpharm-2016-001128. Epub 2017 Mar 18.


Posaconazole therapeutic drug monitoring in clinical practice and longitudinal analysis of the effect of routine laboratory measurements on posaconazole concentrations.

Märtson AG, Veringa A, van den Heuvel ER, Bakker M, Touw DJ, van der Werf TS, Span LFR, Alffenaar JC.

Mycoses. 2019 Aug;62(8):698-705. doi: 10.1111/myc.12948. Epub 2019 Jun 18. Review.


Pharmacokinetics and safety of tobramycin nebulization with the I-neb and PARI-LC Plus in children with cystic fibrosis: A randomized, crossover study.

van Velzen AJ, Uges JWF, Heijerman HGM, Arets BGM, Nuijsink M, van der Wiel-Kooij EC, van Maarseveen EM, van Zanten GA, Pullens B, Touw DJ, Janssens HM.

Br J Clin Pharmacol. 2019 May 21. doi: 10.1111/bcp.13988. [Epub ahead of print]


Vancomycin pharmacokinetic model development in patients on intermittent online hemodiafiltration.

Westra N, Proost JH, Franssen CFM, Wilms EB, van Buren M, Touw DJ.

PLoS One. 2019 May 14;14(5):e0216801. doi: 10.1371/journal.pone.0216801. eCollection 2019.


Limited Sampling Strategies Using Linear Regression and the Bayesian Approach for Therapeutic Drug Monitoring of Moxifloxacin in Tuberculosis Patients.

van den Elsen SHJ, Sturkenboom MGG, Akkerman OW, Manika K, Kioumis IP, van der Werf TS, Johnson JL, Peloquin C, Touw DJ, Alffenaar JC.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00384-19. doi: 10.1128/AAC.00384-19. Print 2019 Jul.


Relevance of the drug-drug interactions between lidocaine and the pharmacokinetic enhancers ritonavir and cobicistat.

Dekkers BGJ, Bierman WFW, Touw DJ, Alffenaar JC.

AIDS. 2019 May 1;33(6):1100-1102. doi: 10.1097/QAD.0000000000002162. No abstract available.


Clinical application of a dried blood spot assay for sirolimus and everolimus in transplant patients.

Veenhof H, Koster RA, Alffenaar JC, van den Berg AP, de Groot MR, Verschuuren EAM, Berger SP, Bakker SJL, Touw DJ.

Clin Chem Lab Med. 2019 Apr 2. pii: /j/cclm.ahead-of-print/cclm-2019-0053/cclm-2019-0053.xml. doi: 10.1515/cclm-2019-0053. [Epub ahead of print]


A volumetric absorptive microsampling LC-MS/MS method for five immunosuppressants and their hematocrit effects.

Koster RA, Niemeijer P, Veenhof H, Hateren KV, Alffenaar JC, Touw DJ.

Bioanalysis. 2019 Mar;11(6):495-508. doi: 10.4155/bio-2018-0312. Epub 2019 Mar 20.


Different Underlying Mechanism Might Explain the Absence of a Significant Difference in Area Under the Concentration-Time Curve of Linezolid for Different ABCB1 Genotypes.

Bolhuis MS, Akkerman OW, Sturkenboom MGG, de Lange WCM, van der Werf TS, Touw DJ, Alffenaar JC.

Ther Drug Monit. 2019 Apr;41(2):253-254. doi: 10.1097/FTD.0000000000000597. No abstract available.


Evaluation of Saliva as a Potential Alternative Sampling Matrix for Therapeutic Drug Monitoring of Levofloxacin in Patients with Multidrug-Resistant Tuberculosis.

Ghimire S, Maharjan B, Jongedijk EM, Kosterink JGW, Ghimire GR, Touw DJ, van der Werf TS, Shrestha B, Alffenaar JC.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02379-18. doi: 10.1128/AAC.02379-18. Print 2019 May.


Vancomycin Pharmacokinetics Throughout Life: Results from a Pooled Population Analysis and Evaluation of Current Dosing Recommendations.

Colin PJ, Allegaert K, Thomson AH, Touw DJ, Dolton M, de Hoog M, Roberts JA, Adane ED, Yamamoto M, Santos-Buelga D, Martín-Suarez A, Simon N, Taccone FS, Lo YL, Barcia E, Struys MMRF, Eleveld DJ.

Clin Pharmacokinet. 2019 Jun;58(6):767-780. doi: 10.1007/s40262-018-0727-5.


Levofloxacin pharmacokinetics, pharmacodynamics and outcome in multidrug-resistant tuberculosis patients.

Ghimire S, Maharjan B, Jongedijk EM, Kosterink JGW, Ghimire GR, Touw DJ, van der Werf TS, Shrestha B, Alffenaar JC.

Eur Respir J. 2019 Apr 18;53(4). pii: 1802107. doi: 10.1183/13993003.02107-2018. Print 2019 Apr. No abstract available.


Posaconazole trough concentrations are not influenced by inflammation: A prospective study.

Märtson AG, Veringa A, Bakker M, van den Heuvel ER, Touw DJ, van der Werf TS, Span LFR, C Alffenaar JW.

Int J Antimicrob Agents. 2019 Mar;53(3):325-329. doi: 10.1016/j.ijantimicag.2019.01.006. Epub 2019 Jan 11.


Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data.

Daskapan A, Tran QTD, Cattaneo D, Gervasoni C, Resnati C, Stienstra Y, Bierman WFW, Kosterink JGW, van der Werf TS, Proost JH, Alffenaar JC, Touw DJ.

Ther Drug Monit. 2019 Feb;41(1):59-65. doi: 10.1097/FTD.0000000000000576.


Active smoking and macrocytosis in the general population: Two population-based cohort studies.

Eisenga MF, Wouters HJCM, Kieneker LM, van der Klauw MM, van der Meer P, Wolffenbuttel BHR, Gaillard CAJM, Kootstra-Ros JE, Touw DJ, Huls G, Bakker SJL.

Am J Hematol. 2019 Feb;94(2):E45-E48. doi: 10.1002/ajh.25346. Epub 2018 Nov 27. No abstract available.


A Systematic Review on the Effect of HIV Infection on the Pharmacokinetics of First-Line Tuberculosis Drugs.

Daskapan A, Idrus LR, Postma MJ, Wilffert B, Kosterink JGW, Stienstra Y, Touw DJ, Andersen AB, Bekker A, Denti P, Hemanth Kumar AK, Jeremiah K, Kwara A, McIlleron H, Meintjes G, van Oosterhout JJ, Ramachandran G, Rockwood N, Wilkinson RJ, van der Werf TS, Alffenaar JC.

Clin Pharmacokinet. 2019 Jun;58(6):747-766. doi: 10.1007/s40262-018-0716-8. Review.


Population Pharmacokinetic Model and Limited Sampling Strategies for Personalized Dosing of Levofloxacin in Tuberculosis Patients.

van den Elsen SHJ, Sturkenboom MGG, Van't Boveneind-Vrubleuskaya N, Skrahina A, van der Werf TS, Heysell SK, Mpagama S, Migliori GB, Peloquin CA, Touw DJ, Alffenaar JC.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01092-18. doi: 10.1128/AAC.01092-18. Print 2018 Dec.


Fish Intake, Circulating Mercury and Mortality in Renal Transplant Recipients.

Sotomayor CG, Gomes-Neto AW, Gans ROB, de Borst MH, Berger SP, Rodrigo R, Navis GJ, Touw DJ, Bakker SJL.

Nutrients. 2018 Oct 3;10(10). pii: E1419. doi: 10.3390/nu10101419.


A design for external quality assessment for the analysis of thiopurine drugs: pitfalls and opportunities.

Robijns K, van Luin M, Jansen RTP, Neef C, Touw DJ.

Clin Chem Lab Med. 2018 Sep 25;56(10):1715-1721. doi: 10.1515/cclm-2018-0116. No abstract available.


Rifampin levels in daily practice: the accuracy of a single measurement.

Vanbrabant TJF, Dijkmans AC, den Hartigh J, Touw DJ, Arend SM.

Neth J Med. 2018 Jul;76(5):235-242.


Pharmacokinetics of 400 mg Locally Infiltrated Ropivacaine After Total Knee Arthroplasty Without Perioperative Tourniquet Use.

Bakker SMK, Fenten MGE, Touw DJ, van den Bemt BJF, Heesterbeek PJC, Scheffer GJ, Stienstra R.

Reg Anesth Pain Med. 2018 Oct;43(7):699-704. doi: 10.1097/AAP.0000000000000816.


Simple and robust LC-MS/MS analysis method for therapeutic drug monitoring of micafungin.

Boonstra JM, Jongedijk EM, Koster RA, Touw DJ, Alffenaar JC.

Bioanalysis. 2018 Jun 1;10(11):877-886. doi: 10.4155/bio-2017-0275. Epub 2018 Jun 4.


Evaluation of dried blood spot sampling for pharmacokinetic research and therapeutic drug monitoring of anti-tuberculosis drugs in children.

Martial LC, Kerkhoff J, Martinez N, Rodríguez M, Coronel R, Molinas G, Roman M, Gomez R, Aguirre S, Jongedijk E, Huisman J, Touw DJ, Pérez D, Chaparro G, Gonzalez F, Aarnoutse RE, Alffenaar JW, Magis-Escurra C.

Int J Antimicrob Agents. 2018 Jul;52(1):109-113. doi: 10.1016/j.ijantimicag.2018.04.020. Epub 2018 May 8.


Self-Reported Smoking, Urine Cotinine, and Risk of Cardiovascular Disease: Findings From the PREVEND (Prevention of Renal and Vascular End-Stage Disease) Prospective Cohort Study.

Kunutsor SK, Spee JM, Kieneker LM, Gansevoort RT, Dullaart RPF, Voerman AJ, Touw DJ, Bakker SJL.

J Am Heart Assoc. 2018 May 2;7(10). pii: e008726. doi: 10.1161/JAHA.118.008726.


Pharmacomicrobiomics: a novel route towards personalized medicine?

Doestzada M, Vila AV, Zhernakova A, Koonen DPY, Weersma RK, Touw DJ, Kuipers F, Wijmenga C, Fu J.

Protein Cell. 2018 May;9(5):432-445. doi: 10.1007/s13238-018-0547-2. Epub 2018 Apr 28. Review.


Active Smoking and Hematocrit and Fasting Circulating Erythropoietin Concentrations in the General Population.

Eisenga MF, Kieneker LM, Touw DJ, Nolte IM, van der Meer P, Huls G, Gaillard CAJM, Bakker SJL.

Mayo Clin Proc. 2018 Mar;93(3):337-343. doi: 10.1016/j.mayocp.2018.01.005.


Test of neural inertia in humans during general anaesthesia.

Kuizenga MH, Colin PJ, Reyntjens KMEM, Touw DJ, Nalbat H, Knotnerus FH, Vereecke HEM, Struys MMRF.

Br J Anaesth. 2018 Mar;120(3):525-536. doi: 10.1016/j.bja.2017.11.072. Epub 2017 Dec 1.


Pharmacokinetics of 2,000 Milligram Ertapenem in Tuberculosis Patients.

Zuur MA, Ghimire S, Bolhuis MS, Wessels AMA, van Altena R, de Lange WCM, Kosterink JGW, Touw DJ, van der Werf TS, Akkerman OW, Alffenaar JWC.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02250-17. doi: 10.1128/AAC.02250-17. Print 2018 May.


Fosfomycin as a potential therapy for the treatment of systemic infections: a population pharmacokinetic model to simulate multiple dosing regimens.

Ortiz Zacarías NV, Dijkmans AC, Burggraaf J, Mouton JW, Wilms EB, van Nieuwkoop C, Touw DJ, Kamerling IMC, Stevens J.

Pharmacol Res Perspect. 2018 Feb;6(1). doi: 10.1002/prp2.378.


[Treating poisoning; how do you choose the best type of gastrointestinal decontamination?]

Verschueren MV, Jansman FGA, Touw DJ, Kramers C.

Ned Tijdschr Geneeskd. 2018;162:D1574. Dutch.


Lack of penetration of amikacin into saliva of tuberculosis patients.

van den Elsen SHJ, Akkerman OW, Huisman JR, Touw DJ, van der Werf TS, Bolhuis MS, Alffenaar JC.

Eur Respir J. 2018 Jan 11;51(1). pii: 1702024. doi: 10.1183/13993003.02024-2017. Print 2018 Jan. No abstract available.


Drugs during pregnancy and breast feeding in women diagnosed with Cystic Fibrosis - An update.

Kroon MAGM, Akkerman-Nijland AM, Rottier BL, Koppelman GH, Akkerman OW, Touw DJ.

J Cyst Fibros. 2018 Jan;17(1):17-25. doi: 10.1016/j.jcf.2017.11.009. Epub 2017 Dec 7. No abstract available.



Sharma PK, Willems TP, Touw DJ, Woudstra W, Erasmus ME, Ebels T.

Ann Thorac Surg. 2017 Dec;104(6):2121-2122. doi: 10.1016/j.athoracsur.2017.04.066. No abstract available.


Systematic Review of Salivary Versus Blood Concentrations of Antituberculosis Drugs and Their Potential for Salivary Therapeutic Drug Monitoring.

van den Elsen SHJ, Oostenbrink LM, Heysell SK, Hira D, Touw DJ, Akkerman OW, Bolhuis MS, Alffenaar JC.

Ther Drug Monit. 2018 Feb;40(1):17-37. doi: 10.1097/FTD.0000000000000462. Review.


Fosfomycin: Pharmacological, Clinical and Future Perspectives.

Dijkmans AC, Zacarías NVO, Burggraaf J, Mouton JW, Wilms EB, van Nieuwkoop C, Touw DJ, Stevens J, Kamerling IMC.

Antibiotics (Basel). 2017 Oct 31;6(4). pii: E24. doi: 10.3390/antibiotics6040024. Review.


Risk factors contributing to a low darunavir plasma concentration.

Daskapan A, Stienstra Y, Kosterink JGW, Bierman WFW, van der Werf TS, Touw DJ, Alffenaar JC.

Br J Clin Pharmacol. 2018 Mar;84(3):456-461. doi: 10.1111/bcp.13464. Epub 2017 Dec 7.


Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Clozapine.

Geers LM, Cohen D, Wehkamp LM, van Hateren K, Koster RA, Fedorenko OY, Semke AV, Bokhan N, Ivanova SA, Kosterink JGW, Loonen AJM, Touw DJ.

J Clin Psychiatry. 2017 Nov/Dec;78(9):e1211-e1218. doi: 10.4088/JCP.16m11164.


Pharmacokinetic Properties of Micafungin in Critically Ill Patients Diagnosed with Invasive Candidiasis.

Boonstra JM, van der Elst KC, Veringa A, Jongedijk EM, Brüggemann RJ, Koster RA, Kampinga GA, Kosterink JG, van der Werf TS, Zijlstra JG, Touw DJ, Alffenaar JWC.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01398-17. doi: 10.1128/AAC.01398-17. Print 2017 Dec.


Twenty-four hour urinary cortisol excretion and the metabolic syndrome in prednisolone-treated renal transplant recipients.

de Vries LV, de Jong WHA, Touw DJ, Berger SP, Navis G, Kema IP, Bakker SJL.

Steroids. 2017 Nov;127:31-39. doi: 10.1016/j.steroids.2017.09.001. Epub 2017 Sep 8.


Improved usability of a multi-infusion setup using a centralized control interface: A task-based usability test.

Doesburg F, Cnossen F, Dieperink W, Bult W, de Smet AM, Touw DJ, Nijsten MW.

PLoS One. 2017 Aug 11;12(8):e0183104. doi: 10.1371/journal.pone.0183104. eCollection 2017.


An acute oral intoxication with haloperidol decanoate.

Dekkers BGJ, Eck RJ, Ter Maaten JC, Touw DJ.

Am J Emerg Med. 2017 Sep;35(9):1387.e1-1387.e2. doi: 10.1016/j.ajem.2017.07.013. Epub 2017 Jul 5.


Ocular myasthenic syndrome, adverse reaction to omalizumab? A case report.

Kalteren WS, Schreurs MWJ, Jorritsma-Smit A, Touw DJ, de Jong JW, Zweers PGMA, Reesink FE.

Br J Clin Pharmacol. 2017 Oct;83(10):2330-2332. doi: 10.1111/bcp.13338. Epub 2017 Jun 19. No abstract available.

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