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Mycoplasma genitalium infection among HIV-infected pregnant African women and implications for mother-to-child transmission of HIV.

Roxby AC, Yuhas K, Farquhar C, Bosire R, Mbori-Ngacha D, Richardson BA, Totten PA, John-Stewart G.

AIDS. 2019 Aug 2. doi: 10.1097/QAD.0000000000002335. [Epub ahead of print]


Methods for Antimicrobial Susceptibility Testing for Human Mycoplasmas; Approved Guideline [Internet].

Waites KB, Bade DJ, Bébéar C, Brown SD, Davidson MK, Duffy LB, Kenny G, Matlow A, Shortridge D, Talkington D, Totten PA, Watts JL, Zheng X.

Wayne (PA): Clinical and Laboratory Standards Institute; 2011 Oct.


Lack of association between the S83I ParC mutation in Mycoplasma genitalium and treatment outcomes among men who have sex with men with nongonococcal urethritis.

Chambers LC, Jensen JS, Morgan JL, Lowens MS, Romano SS, Totten PA, Soge OO, Hughes JP, Golden MR, Manhart LE.

Sex Transm Dis. 2019 Jun 26. doi: 10.1097/OLQ.0000000000001035. [Epub ahead of print]


Design and Validation of Transcription-Mediated-Amplification Nucleic Acid Amplification Tests for Mycoplasma genitalium.

Kirkconnell B, Weinbaum B, Santos K, Le Nguyen T, Vinluan B, Astete S, Wood GE, Totten PA, Getman DK.

J Clin Microbiol. 2019 Jul 26;57(8). pii: e00264-19. doi: 10.1128/JCM.00264-19. Print 2019 Aug.


Long Duration of Asymptomatic Mycoplasma genitalium Infection After Syndromic Treatment for Nongonococcal Urethritis.

Romano SS, Jensen JS, Lowens MS, Morgan JL, Chambers LC, Robinson TS, Totten PA, Soge OO, Golden MR, Manhart LE.

Clin Infect Dis. 2019 Jun 18;69(1):113-120. doi: 10.1093/cid/ciy843.


Mycoplasma genitalium Nonadherent Phase Variants Arise by Multiple Mechanisms and Escape Antibody-Dependent Growth Inhibition.

Burgos R, Wood GE, Iverson-Cabral SL, Totten PA.

Infect Immun. 2018 Mar 22;86(4). pii: e00866-17. doi: 10.1128/IAI.00866-17. Print 2018 Apr.


Toll-like receptor variants and cervical Atopobium vaginae infection in women with pelvic inflammatory disease.

Taylor BD, Totten PA, Astete SG, Ferris MJ, Martin DH, Ness RB, Haggerty CL.

Am J Reprod Immunol. 2018 Feb;79(2). doi: 10.1111/aji.12804. Epub 2017 Dec 29.


The Unique Microbiology and Molecular Pathogenesis of Mycoplasma genitalium.

McGowin CL, Totten PA.

J Infect Dis. 2017 Jul 15;216(suppl_2):S382-S388. doi: 10.1093/infdis/jix172. Review.


Association of Recent Bacterial Vaginosis With Acquisition of Mycoplasma genitalium.

Lokken EM, Balkus JE, Kiarie J, Hughes JP, Jaoko W, Totten PA, McClelland RS, Manhart LE.

Am J Epidemiol. 2017 Jul 15;186(2):194-201. doi: 10.1093/aje/kwx043.


Experimental Infection of Pig-Tailed Macaques (Macaca nemestrina) with Mycoplasma genitalium.

Wood GE, Patton DL, Cummings PK, Iverson-Cabral SL, Totten PA.

Infect Immun. 2017 Jan 26;85(2). pii: e00738-16. doi: 10.1128/IAI.00738-16. Print 2017 Feb.


Identification of novel microbes associated with pelvic inflammatory disease and infertility.

Haggerty CL, Totten PA, Tang G, Astete SG, Ferris MJ, Norori J, Bass DC, Martin DH, Taylor BD, Ness RB.

Sex Transm Infect. 2016 Sep;92(6):441-6. doi: 10.1136/sextrans-2015-052285. Epub 2016 Jan 29.


Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial.

Khosropour CM, Manhart LE, Gillespie CW, Lowens MS, Golden MR, Jensen NL, Kenny GE, Totten PA.

Sex Transm Infect. 2015 Aug;91(5):308-13. doi: 10.1136/sextrans-2014-051859. Epub 2015 Jan 23.


MG428 is a novel positive regulator of recombination that triggers mgpB and mgpC gene variation in Mycoplasma genitalium.

Burgos R, Totten PA.

Mol Microbiol. 2014 Oct;94(2):290-306. doi: 10.1111/mmi.12760. Epub 2014 Sep 5.


Suboptimal adherence to doxycycline and treatment outcomes among men with non-gonococcal urethritis: a prospective cohort study.

Khosropour CM, Manhart LE, Colombara DV, Gillespie CW, Lowens MS, Totten PA, Golden MR, Simoni J.

Sex Transm Infect. 2014 Feb;90(1):3-7. doi: 10.1136/sextrans-2013-051174. Epub 2013 Oct 8.


Persistence, immune response, and antigenic variation of Mycoplasma genitalium in an experimentally infected pig-tailed macaque (Macaca nemestrina).

Wood GE, Iverson-Cabral SL, Patton DL, Cummings PK, Cosgrove Sweeney YT, Totten PA.

Infect Immun. 2013 Aug;81(8):2938-51. doi: 10.1128/IAI.01322-12. Epub 2013 Jun 3.


Standard treatment regimens for nongonococcal urethritis have similar but declining cure rates: a randomized controlled trial.

Manhart LE, Gillespie CW, Lowens MS, Khosropour CM, Colombara DV, Golden MR, Hakhu NR, Thomas KK, Hughes JP, Jensen NL, Totten PA.

Clin Infect Dis. 2013 Apr;56(7):934-42. doi: 10.1093/cid/cis1022. Epub 2012 Dec 7.


Standardized methods and quality control limits for agar and broth microdilution susceptibility testing of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum.

Waites KB, Duffy LB, Bébéar CM, Matlow A, Talkington DF, Kenny GE, Totten PA, Bade DJ, Zheng X, Davidson MK, Shortridge VD, Watts JL, Brown SD.

J Clin Microbiol. 2012 Nov;50(11):3542-7. doi: 10.1128/JCM.01439-12. Epub 2012 Aug 22.


RecA mediates MgpB and MgpC phase and antigenic variation in Mycoplasma genitalium, but plays a minor role in DNA repair.

Burgos R, Wood GE, Young L, Glass JI, Totten PA.

Mol Microbiol. 2012 Aug;85(4):669-83. doi: 10.1111/j.1365-2958.2012.08130.x. Epub 2012 Jul 5.


Ureaplasma urealyticum is associated with nongonococcal urethritis among men with fewer lifetime sexual partners: a case-control study.

Wetmore CM, Manhart LE, Lowens MS, Golden MR, Jensen NL, Astete SG, Whittington WL, Totten PA.

J Infect Dis. 2011 Oct 15;204(8):1274-82. doi: 10.1093/infdis/jir517.


Detection of Mycoplasma genitalium-reactive cervicovaginal antibodies among infected women.

Iverson-Cabral SL, Manhart LE, Totten PA.

Clin Vaccine Immunol. 2011 Oct;18(10):1783-6. doi: 10.1128/CVI.05174-11. Epub 2011 Aug 3.


Demographic, behavioral, and clinical characteristics of men with nongonococcal urethritis differ by etiology: a case-comparison study.

Wetmore CM, Manhart LE, Lowens MS, Golden MR, Whittington WL, Xet-Mull AM, Astete SG, McFarland NL, McDougal SJ, Totten PA.

Sex Transm Dis. 2011 Mar;38(3):180-6. doi: 10.1097/OLQ.0b013e3182040de9.


Comprehensive assessment of sociodemographic and behavioral risk factors for Mycoplasma genitalium infection in women.

Hancock EB, Manhart LE, Nelson SJ, Kerani R, Wroblewski JK, Totten PA.

Sex Transm Dis. 2010 Dec;37(12):777-83. doi: 10.1097/OLQ.0b013e3181e8087e.


Differential association of ureaplasma species with non-gonococcal urethritis in heterosexual men.

Ondondo RO, Whittington WL, Astete SG, Totten PA.

Sex Transm Infect. 2010 Aug;86(4):271-5. doi: 10.1136/sti.2009.040394. Epub 2010 May 10.


The demographic, sexual health and behavioural correlates of Mycoplasma genitalium infection among women with clinically suspected pelvic inflammatory disease.

Short VL, Totten PA, Ness RB, Astete SG, Kelsey SF, Murray P, Haggerty CL.

Sex Transm Infect. 2010 Feb;86(1):29-31. doi: 10.1136/sti.2009.037721. Epub 2009 Aug 24.


Clinical presentation of Mycoplasma genitalium Infection versus Neisseria gonorrhoeae infection among women with pelvic inflammatory disease.

Short VL, Totten PA, Ness RB, Astete SG, Kelsey SF, Haggerty CL.

Clin Infect Dis. 2009 Jan 1;48(1):41-7. doi: 10.1086/594123.


Clinical characteristics of bacterial vaginosis among women testing positive for fastidious bacteria.

Haggerty CL, Totten PA, Ferris M, Martin DH, Hoferka S, Astete SG, Ondondo R, Norori J, Ness RB.

Sex Transm Infect. 2009 Aug;85(4):242-8. doi: 10.1136/sti.2008.032821. Epub 2008 Nov 12.


Failure of cefoxitin and doxycycline to eradicate endometrial Mycoplasma genitalium and the consequence for clinical cure of pelvic inflammatory disease.

Haggerty CL, Totten PA, Astete SG, Lee S, Hoferka SL, Kelsey SF, Ness RB.

Sex Transm Infect. 2008 Oct;84(5):338-42. doi: 10.1136/sti.2008.030486. Epub 2008 Apr 29.


High Mycoplasma genitalium organism burden is associated with shedding of HIV-1 DNA from the cervix.

Manhart LE, Mostad SB, Baeten JM, Astete SG, Mandaliya K, Totten PA.

J Infect Dis. 2008 Mar 1;197(5):733-6. doi: 10.1086/526501.


Mycoplasma genitalium among women with nongonococcal, nonchlamydial pelvic inflammatory disease.

Haggerty CL, Totten PA, Astete SG, Ness RB.

Infect Dis Obstet Gynecol. 2006;2006:30184.


Mycoplasma genitalium among young adults in the United States: an emerging sexually transmitted infection.

Manhart LE, Holmes KK, Hughes JP, Houston LS, Totten PA.

Am J Public Health. 2007 Jun;97(6):1118-25. Epub 2007 Apr 26.


A randomized, double-blind study comparing single-dose rifalazil with single-dose azithromycin for the empirical treatment of nongonococcal urethritis in men.

Stamm WE, Batteiger BE, McCormack WM, Totten PA, Sternlicht A, Kivel NM; Rifalazil Study Group.

Sex Transm Dis. 2007 Aug;34(8):545-52.


Mycoplasma genitalium infection and persistence in a cohort of female sex workers in Nairobi, Kenya.

Cohen CR, Nosek M, Meier A, Astete SG, Iverson-Cabral S, Mugo NR, Totten PA.

Sex Transm Dis. 2007 May;34(5):274-9.


Detection of Mycoplasma genitalium in women with laparoscopically diagnosed acute salpingitis.

Cohen CR, Mugo NR, Astete SG, Odondo R, Manhart LE, Kiehlbauch JA, Stamm WE, Waiyaki PG, Totten PA.

Sex Transm Infect. 2005 Dec;81(6):463-6.


Changes in the etiology of sexually transmitted diseases in Botswana between 1993 and 2002: implications for the clinical management of genital ulcer disease.

Paz-Bailey G, Rahman M, Chen C, Ballard R, Moffat HJ, Kenyon T, Kilmarx PH, Totten PA, Astete S, Boily MC, Ryan C.

Clin Infect Dis. 2005 Nov 1;41(9):1304-12. Epub 2005 Oct 4.


Detection of novel organisms associated with salpingitis, by use of 16S rDNA polymerase chain reaction.

Hebb JK, Cohen CR, Astete SG, Bukusi EA, Totten PA.

J Infect Dis. 2004 Dec 15;190(12):2109-20. Epub 2004 Nov 11.


Rescreening for gonorrhea and chlamydial infection through the mail: a randomized trial.

Sparks R, Helmers JR, Handsfield HH, Totten PA, Holmes KK, Wroblewski JK, Malinski C, Golden MR.

Sex Transm Dis. 2004 Feb;31(2):113-6.


Development and performance of a microwell-plate-based polymerase chain reaction assay for Mycoplasma genitalium.

Dutro SM, Hebb JK, Garin CA, Hughes JP, Kenny GE, Totten PA.

Sex Transm Dis. 2003 Oct;30(10):756-63.


Pilot study of COBAS PCR and ligase chain reaction for detection of rectal infections due to Chlamydia trachomatis.

Golden MR, Astete SG, Galvan R, Lucchetti A, Sanchez J, Celum CL, Whittington WL, Stamm WE, Holmes KK, Totten PA.

J Clin Microbiol. 2003 May;41(5):2174-5.


Mucopurulent cervicitis and Mycoplasma genitalium.

Manhart LE, Critchlow CW, Holmes KK, Dutro SM, Eschenbach DA, Stevens CE, Totten PA.

J Infect Dis. 2003 Feb 15;187(4):650-7. Epub 2003 Jan 29. Erratum in: J Infect Dis. 2004 Aug 15;190(4):866.


The etiology and management of genital ulcers in the Dominican Republic and Peru.

Sanchez J, Volquez C, Totten PA, Campos PE, Ryan C, Catlin M, Hasbun J, Rosado De Quiñones M, Sanchez C, De Lister MB, Weiss JB, Ashley R, Holmes KK.

Sex Transm Dis. 2002 Oct;29(10):559-67.


Association between Mycoplasma genitalium and acute endometritis.

Cohen CR, Manhart LE, Bukusi EA, Astete S, Brunham RC, Holmes KK, Sinei SK, Bwayo JJ, Totten PA.

Lancet. 2002 Mar 2;359(9308):765-6.


Association of Mycoplasma genitalium with nongonococcal urethritis in heterosexual men.

Totten PA, Schwartz MA, Sjöström KE, Kenny GE, Handsfield HH, Weiss JB, Whittington WL.

J Infect Dis. 2001 Jan 15;183(2):269-276. Epub 2000 Dec 21. Erratum in: J Infect Dis. 2003 May 1;187(9):1506.


Etiology of genital ulcer disease in Dakar, Senegal, and comparison of PCR and serologic assays for detection of Haemophilus ducreyi.

Totten PA, Kuypers JM, Chen CY, Alfa MJ, Parsons LM, Dutro SM, Morse SA, Kiviat NB.

J Clin Microbiol. 2000 Jan;38(1):268-73.

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