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Items: 5

1.

PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer.

Chauhan SS, Toth RK, Jensen CC, Casillas AL, Kashatus DF, Warfel NA.

Oncogene. 2020 Jan 28. doi: 10.1038/s41388-020-1168-9. [Epub ahead of print]

PMID:
31992853
2.

Hypoxia-induced PIM kinase and laminin-activated integrin α6 mediate resistance to PI3K inhibitors in bone-metastatic CRPC.

Toth RK, Tran JD, Muldong MT, Nollet EA, Schulz VV, Jensen CC, Hazlehurst LA, Corey E, Durden D, Jamieson C, Miranti CK, Warfel NA.

Am J Clin Exp Urol. 2019 Aug 15;7(4):297-312. eCollection 2019.

3.

Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents.

Casillas AL, Toth RK, Sainz AG, Singh N, Desai AA, Kraft AS, Warfel NA.

Clin Cancer Res. 2018 Jan 1;24(1):169-180. doi: 10.1158/1078-0432.CCR-17-1318. Epub 2017 Oct 30.

4.

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia.

Toth RK, Warfel NA.

Antioxidants (Basel). 2017 Apr 6;6(2). pii: E27. doi: 10.3390/antiox6020027. Review.

5.

DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC.

Rai K, Sarkar S, Broadbent TJ, Voas M, Grossmann KF, Nadauld LD, Dehghanizadeh S, Hagos FT, Li Y, Toth RK, Chidester S, Bahr TM, Johnson WE, Sklow B, Burt R, Cairns BR, Jones DA.

Cell. 2010 Sep 17;142(6):930-42. doi: 10.1016/j.cell.2010.08.030.

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