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Items: 45

1.

An MRI measure of degenerative and cerebrovascular pathology in Alzheimer disease.

Brickman AM, Tosto G, Gutierrez J, Andrews H, Gu Y, Narkhede A, Rizvi B, Guzman V, Manly JJ, Vonsattel JP, Schupf N, Mayeux R.

Neurology. 2018 Oct 9;91(15):e1402-e1412. doi: 10.1212/WNL.0000000000006310. Epub 2018 Sep 14.

PMID:
30217936
2.

Clinical Experience with Cerebrospinal Fluid Aβ42, Total and Phosphorylated Tau in the Evaluation of 1,016 Individuals for Suspected Dementia.

Tariciotti L, Casadei M, Honig LS, Teich AF, McKhann Ii GM, Tosto G, Mayeux R.

J Alzheimers Dis. 2018;65(4):1417-1425. doi: 10.3233/JAD-180548.

PMID:
30149454
3.

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtimäki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Vardarajan B, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X; Alzheimer’s Disease Sequencing Project, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA.

Mol Psychiatry. 2018 Aug 14. doi: 10.1038/s41380-018-0112-7. [Epub ahead of print]

PMID:
30108311
4.

Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease.

Raghavan NS, Brickman AM, Andrews H, Manly JJ, Schupf N, Lantigua R, Wolock CJ, Kamalakaran S, Petrovski S, Tosto G, Vardarajan BN, Goldstein DB, Mayeux R; Alzheimer's Disease Sequencing Project.

Ann Clin Transl Neurol. 2018 May 24;5(7):832-842. doi: 10.1002/acn3.582. eCollection 2018 Jul.

5.

Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP.

Nafikov RA, Nato AQ Jr, Sohi H, Wang B, Brown L, Horimoto AR, Vardarajan BN, Barral SM, Tosto G, Mayeux RP, Thornton TA, Blue E, Wijsman EM.

Genet Epidemiol. 2018 Sep;42(6):500-515. doi: 10.1002/gepi.22133. Epub 2018 Jun 3.

PMID:
29862559
6.

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease.

Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, Saykin AJ, Masters CL, Ringman JM, Fӧrster S, Schofield PR, Sperling RA, Johnson KA, Chhatwal JP, Salloway S, Correia S, Jack CR Jr, Weiner M, Bateman RJ, Morris JC, Mayeux R, Brickman AM; Dominantly Inherited Alzheimer Network.

PLoS One. 2018 May 9;13(5):e0195838. doi: 10.1371/journal.pone.0195838. eCollection 2018.

7.

Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.

Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj A, Thornton T, DeStefano A, Martin E, Wang LS, Brown L, Bush W, van Duijn C, Goate A, Farrer L, Haines JL, Boerwinkle E, Schellenberg G, Wijsman E, Pericak-Vance MA, Mayeux R; Alzheimer's Disease Sequencing Project, Wang LS.

Ann Clin Transl Neurol. 2018 Mar 13;5(4):406-417. doi: 10.1002/acn3.537. eCollection 2018 Apr.

8.

Cognitive phenotypes in multiple sclerosis.

Leavitt VM, Tosto G, Riley CS.

J Neurol. 2018 Mar;265(3):562-566. doi: 10.1007/s00415-018-8747-5. Epub 2018 Jan 22.

PMID:
29356970
9.

The effect of white matter hyperintensities on cognition is mediated by cortical atrophy.

Rizvi B, Narkhede A, Last BS, Budge M, Tosto G, Manly JJ, Schupf N, Mayeux R, Brickman AM.

Neurobiol Aging. 2018 Apr;64:25-32. doi: 10.1016/j.neurobiolaging.2017.12.006. Epub 2017 Dec 16.

PMID:
29328963
10.

Prosodic Impairment in Dementia: Review of the Literature.

Misiewicz S, Brickman AM, Tosto G.

Curr Alzheimer Res. 2018;15(2):157-163. doi: 10.2174/1567205014666171030115624.

PMID:
29086698
11.

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.

Cruchaga C, Del-Aguila JL, Saef B, Black K, Fernandez MV, Budde J, Ibanez L, Deming Y, Kapoor M, Tosto G, Mayeux RP, Holtzman DM, Fagan AM, Morris JC, Bateman RJ, Goate AM; Dominantly Inherited Alzheimer Network (DIAN); Disease Neuroimaging Initiative (ADNI); NIA-LOAD family study, Harari O.

Alzheimers Dement. 2018 Feb;14(2):205-214. doi: 10.1016/j.jalz.2017.08.013. Epub 2017 Sep 21.

PMID:
28943286
12.

Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease.

Vardarajan BN, Tosto G, Lefort R, Yu L, Bennett DA, De Jager PL, Barral S, Reyes-Dumeyer D, Nagy PL, Lee JH, Cheng R, Medrano M, Lantigua R, Rogaeva E, St George-Hyslop P, Mayeux R.

Neurol Genet. 2017 Aug 24;3(5):e178. doi: 10.1212/NXG.0000000000000178. eCollection 2017 Oct.

13.

Genetics of Alzheimer's Disease: the Importance of Polygenic and Epistatic Components.

Raghavan N, Tosto G.

Curr Neurol Neurosci Rep. 2017 Aug 21;17(10):78. doi: 10.1007/s11910-017-0787-1. Review.

14.

Polygenic risk scores in familial Alzheimer disease.

Tosto G, Bird TD, Tsuang D, Bennett DA, Boeve BF, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Bertlesen S, Graff-Radford NR, Medrano M, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R.

Neurology. 2017 Mar 21;88(12):1180-1186. doi: 10.1212/WNL.0000000000003734. Epub 2017 Feb 17.

15.

Association of Cardiovascular Risk Factors and Stroke With Alzheimer Disease-Reply.

Tosto G, Mayeux R.

JAMA Neurol. 2017 Jan 1;74(1):129-130. doi: 10.1001/jamaneurol.2016.4384. No abstract available.

PMID:
27842174
16.

Use of "omics" technologies to dissect neurologic disease.

Tosto G, Reitz C.

Handb Clin Neurol. 2016;138:91-106. doi: 10.1016/B978-0-12-802973-2.00006-9. Review.

PMID:
27637954
17.

Genomics of Alzheimer's disease: Value of high-throughput genomic technologies to dissect its etiology.

Tosto G, Reitz C.

Mol Cell Probes. 2016 Dec;30(6):397-403. doi: 10.1016/j.mcp.2016.09.001. Epub 2016 Sep 13. Review.

PMID:
27618776
18.

The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.

Tosto G, Bird TD, Bennett DA, Boeve BF, Brickman AM, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Graff-Radford NR, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R; National Institute on Aging Late-Onset Alzheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD) Family Study Group.

JAMA Neurol. 2016 Oct 1;73(10):1231-1237. doi: 10.1001/jamaneurol.2016.2539.

19.

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network.

Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, Saykin AJ, Masters CL, Ringman JM, Ryan NS, Förster S, Laske C, Schofield PR, Sperling RA, Salloway S, Correia S, Jack C Jr, Weiner M, Bateman RJ, Morris JC, Mayeux R, Brickman AM; Dominantly Inherited Alzheimer Network.

Ann Neurol. 2016 Jun;79(6):929-39. doi: 10.1002/ana.24647. Epub 2016 Apr 27.

20.

Promising Therapies for Alzheimer's Disease.

Confaloni A, Tosto G, Tata AM.

Curr Pharm Des. 2016;22(14):2050-6. Review.

PMID:
26876218
21.

Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates.

Tosto G, Monsell SE, Hawes SE, Bruno G, Mayeux R.

J Alzheimers Dis. 2016;49(4):1085-93. doi: 10.3233/JAD-150244.

22.

Sociodemographic and Clinical Changes Over Time of Individuals Evaluated for Cognitive Disturbances: Good or Bad News?

Canevelli M, Cesari M, Trobia F, Talarico G, Tosto G, Letteri F, Reniè R, Gasparini M, Bruno G.

J Am Med Dir Assoc. 2015 Dec;16(12):1095-6. doi: 10.1016/j.jamda.2015.09.013.

PMID:
26593304
23.

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.

Tosto G, Fu H, Vardarajan BN, Lee JH, Cheng R, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Elkind MS, Wright CB, Sacco RL, Pericak-Vance M, Farrer L, Rogaeva E, St George-Hyslop P, Reitz C, Mayeux R.

Ann Clin Transl Neurol. 2015 Aug;2(8):810-20. doi: 10.1002/acn3.223. Epub 2015 Jun 18.

24.

Pattern of extrapyramidal signs in Alzheimer's disease.

Tosto G, Monsell SE, Hawes SE, Mayeux R.

J Neurol. 2015 Nov;262(11):2548-56. doi: 10.1007/s00415-015-7886-1. Epub 2015 Sep 4.

25.

The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment.

Tosto G, Zimmerman ME, Hamilton JL, Carmichael OT, Brickman AM; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2015 Dec;11(12):1510-1519. doi: 10.1016/j.jalz.2015.05.014. Epub 2015 Jun 13.

26.

Neuropsychological predictors of rapidly progressive Alzheimer's disease.

Tosto G, Gasparini M, Brickman AM, Letteri F, Renie' R, Piscopo P, Talarico G, Canevelli M, Confaloni A, Bruno G.

Acta Neurol Scand. 2015 Dec;132(6):417-22. doi: 10.1111/ane.12415. Epub 2015 Apr 22.

PMID:
25903925
27.

SORL1 Gene is Associated with the Conversion from Mild Cognitive Impairment to Alzheimer's Disease.

Piscopo P, Tosto G, Belli C, Talarico G, Galimberti D, Gasparini M, Canevelli M, Poleggi A, Crestini A, Albani D, Forloni G, Lucca U, Quadri P, Tettamanti M, Fenoglio C, Scarpini E, Bruno G, Vanacore N, Confaloni A.

J Alzheimers Dis. 2015;46(3):771-6. doi: 10.3233/JAD-141551.

PMID:
25881907
28.

Binge eating and fast cognitive worsening in an early-onset bvFTD patient carrying C9ORF72 expansion.

Talarico G, Canevelli M, Tosto G, Piscopo P, Confaloni A, Galimberti D, Fenoglio C, Scarpini E, Gasparini M, Bruno G.

Neurocase. 2015;21(5):543-7. doi: 10.1080/13554794.2014.951056. Epub 2014 Aug 26.

PMID:
25158292
29.

Predicting aggressive decline in mild cognitive impairment: the importance of white matter hyperintensities.

Tosto G, Zimmerman ME, Carmichael OT, Brickman AM; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2014 Jul 1;71(7):872-7. doi: 10.1001/jamaneurol.2014.667.

30.

Familial Alzheimer's disease sustained by presenilin 2 mutations: systematic review of literature and genotype-phenotype correlation.

Canevelli M, Piscopo P, Talarico G, Vanacore N, Blasimme A, Crestini A, Tosto G, Troili F, Lenzi GL, Confaloni A, Bruno G.

Neurosci Biobehav Rev. 2014 May;42:170-9. doi: 10.1016/j.neubiorev.2014.02.010. Epub 2014 Mar 2. Review.

PMID:
24594196
31.

Electrochemotherapy for the treatment of recurring aponeurotic fibromatosis in a dog.

Spugnini EP, Di Tosto G, Salemme S, Pecchia L, Fanciulli M, Baldi A.

Can Vet J. 2013 Jun;54(6):606-9.

32.

Genome-wide association studies in Alzheimer's disease: a review.

Tosto G, Reitz C.

Curr Neurol Neurosci Rep. 2013 Oct;13(10):381. doi: 10.1007/s11910-013-0381-0. Review.

33.

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).

Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R; Alzheimer's Disease Genetics Consortium (ADGC).

Transl Psychiatry. 2013 May 14;3:e256. doi: 10.1038/tp.2013.13.

34.

Efficacy of sertraline in a patient with Neuro-Beçhet's disease.

Tosto G, Letteri F, Canevelli M, Bruno G.

J Clin Neurosci. 2013 Jun;20(6):896-7. doi: 10.1016/j.jocn.2012.05.044. Epub 2013 Mar 7.

PMID:
23477873
35.

White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease?

Provenzano FA, Muraskin J, Tosto G, Narkhede A, Wasserman BT, Griffith EY, Guzman VA, Meier IB, Zimmerman ME, Brickman AM; Alzheimer's Disease Neuroimaging Initiative.

JAMA Neurol. 2013 Apr;70(4):455-61. doi: 10.1001/jamaneurol.2013.1321.

36.

White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment.

Guzman VA, Carmichael OT, Schwarz C, Tosto G, Zimmerman ME, Brickman AM; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2013 Oct;9(5 Suppl):S124-31. doi: 10.1016/j.jalz.2012.11.009. Epub 2013 Jan 30.

37.

Restless legs syndrome in a group of patients with Alzheimer's disease.

Talarico G, Canevelli M, Tosto G, Vanacore N, Letteri F, Prastaro M, Troili F, Gasparini M, Lenzi GL, Bruno G.

Am J Alzheimers Dis Other Demen. 2013 Mar;28(2):165-70. doi: 10.1177/1533317512470208. Epub 2012 Dec 21.

PMID:
23264651
38.

Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

Reitz C, Tosto G, Mayeux R, Luchsinger JA; NIA-LOAD/NCRAD Family Study Group; Alzheimer's Disease Neuroimaging Initiative.

PLoS One. 2012;7(12):e50354. doi: 10.1371/journal.pone.0050354. Epub 2012 Dec 12.

39.

Rivastigmine in the treatment of hypersexuality in Alzheimer disease.

Canevelli M, Talarico G, Tosto G, Troili F, Lenzi GL, Bruno G.

Alzheimer Dis Assoc Disord. 2013 Jul-Sep;27(3):287-8. doi: 10.1097/WAD.0b013e31825c85ae.

PMID:
22683665
40.

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.

Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Bossù P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O'Donovan M, Valdivieso F, Caffarra P, Scarpini E, Combarros O, Buée L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alpérovitch A, Lathrop M, Trégouët DA, Williams J, Amouyel P.

Mol Psychiatry. 2013 Apr;18(4):461-70. doi: 10.1038/mp.2012.14. Epub 2012 Mar 20. Erratum in: Mol Psychiatry. 2013 Apr;18(4):521. Caffara, P [corrected to Caffarra, P].

41.

Prosodic impairment in Alzheimer's disease: assessment and clinical relevance.

Tosto G, Gasparini M, Lenzi GL, Bruno G.

J Neuropsychiatry Clin Neurosci. 2011 Spring;23(2):E21-3. doi: 10.1176/appi.neuropsych.23.2.E21. No abstract available.

PMID:
21677212
42.

Presenilin 2 mutation R71W in an Italian early-onset sporadic Alzheimer's disease case.

Piscopo P, Talarico G, Malvezzi-Campeggi L, Crestini A, Rivabene R, Gasparini M, Tosto G, Vanacore N, Lenzi GL, Bruno G, Confaloni A.

J Neurol. 2011 Nov;258(11):2043-7. doi: 10.1007/s00415-011-6066-1. Epub 2011 May 5.

PMID:
21544564
43.

Serotonin toxicity: a short review of the literature and two case reports involving citalopram.

Talarico G, Tosto G, Pietracupa S, Piacentini E, Canevelli M, Lenzi GL, Bruno G.

Neurol Sci. 2011 Jun;32(3):507-9. doi: 10.1007/s10072-011-0546-z. Epub 2011 Apr 14. Review.

PMID:
21491099
44.

Effect of citalopram in treating hypersexuality in an Alzheimer's disease case.

Tosto G, Talarico G, Lenzi GL, Bruno G.

Neurol Sci. 2008 Sep;29(4):269-70. doi: 10.1007/s10072-008-0979-1. Epub 2008 Sep 20.

PMID:
18810603
45.

Emerging oral drugs for multiple sclerosis.

Gasperini C, Cefaro LA, Borriello G, Tosto G, Prosperini L, Pozzilli C.

Expert Opin Emerg Drugs. 2008 Sep;13(3):465-77. doi: 10.1517/14728214.13.3.465 . Review.

PMID:
18764723

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