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Items: 1 to 50 of 112

1.

Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.

Orlov DS, Shamova OV, Eliseev IE, Zharkova MS, Chakchir OB, Antcheva N, Zachariev S, Panteleev PV, Kokryakov VN, Ovchinnikova TV, Tossi A.

Mar Drugs. 2019 Jun 23;17(6). pii: E376. doi: 10.3390/md17060376.

2.

Mixed Fluorinated/Hydrogenated Self-Assembled Monolayer-Protected Gold Nanoparticles: In Silico and In Vitro Behavior.

Marson D, Guida F, Şologan M, Boccardo S, Pengo P, Perissinotto F, Iacuzzi V, Pellizzoni E, Polizzi S, Casalis L, Pasquato L, Pacor S, Tossi A, Posocco P.

Small. 2019 Apr;15(17):e1900323. doi: 10.1002/smll.201900323. Epub 2019 Apr 3.

PMID:
30941901
3.

Selection and redesign for high selectivity of membrane-active antimicrobial peptides from a dedicated sequence/function database.

Rončević T, Vukičević D, Krce L, Benincasa M, Aviani I, Maravić A, Tossi A.

Biochim Biophys Acta Biomembr. 2019 Apr 1;1861(4):827-834. doi: 10.1016/j.bbamem.2019.01.017. Epub 2019 Jan 30.

PMID:
30710514
4.

Membrane-active antimicrobial peptide identified in Rana arvalis by targeted DNA sequencing.

Rončević T, Krce L, Gerdol M, Pacor S, Benincasa M, Guida F, Aviani I, Čikeš-Čulić V, Pallavicini A, Maravić A, Tossi A.

Biochim Biophys Acta Biomembr. 2019 Mar 1;1861(3):651-659. doi: 10.1016/j.bbamem.2018.12.014. Epub 2018 Dec 20.

PMID:
30578771
5.

Parallel identification of novel antimicrobial peptide sequences from multiple anuran species by targeted DNA sequencing.

Rončević T, Gerdol M, Spazzali F, Florian F, Mekinić S, Tossi A, Pallavicini A.

BMC Genomics. 2018 Nov 20;19(1):827. doi: 10.1186/s12864-018-5225-5.

6.

Influence of Bacterial Biofilm Polysaccharide Structure on Interactions with Antimicrobial Peptides: A Study on Klebsiella pneumoniae.

Bellich B, Lagatolla C, Tossi A, Benincasa M, Cescutti P, Rizzo R.

Int J Mol Sci. 2018 Jun 6;19(6). pii: E1685. doi: 10.3390/ijms19061685.

7.

Antibacterial Activity Affected by the Conformational Flexibility in Glycine-Lysine Based α-Helical Antimicrobial Peptides.

Rončević T, Vukičević D, Ilić N, Krce L, Gajski G, Tonkić M, Goić-Barišić I, Zoranić L, Sonavane Y, Benincasa M, Juretić D, Maravić A, Tossi A.

J Med Chem. 2018 Apr 12;61(7):2924-2936. doi: 10.1021/acs.jmedchem.7b01831. Epub 2018 Mar 29.

PMID:
29553266
8.

The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome.

Mardirossian M, Pérébaskine N, Benincasa M, Gambato S, Hofmann S, Huter P, Müller C, Hilpert K, Innis CA, Tossi A, Wilson DN.

Cell Chem Biol. 2018 May 17;25(5):530-539.e7. doi: 10.1016/j.chembiol.2018.02.004. Epub 2018 Mar 8.

9.

Regional Biophysics Conference - RBC2016.

Dalla Serra M, Tossi A.

Eur Biophys J. 2017 Dec;46(8):689-690. doi: 10.1007/s00249-017-1265-z. No abstract available.

PMID:
29128893
10.

Gold nanoparticles with patterned surface monolayers for nanomedicine: current perspectives.

Pengo P, Şologan M, Pasquato L, Guida F, Pacor S, Tossi A, Stellacci F, Marson D, Boccardo S, Pricl S, Posocco P.

Eur Biophys J. 2017 Dec;46(8):749-771. doi: 10.1007/s00249-017-1250-6. Epub 2017 Sep 1. Review.

11.

Myticalins: A Novel Multigenic Family of Linear, Cationic Antimicrobial Peptides from Marine Mussels (Mytilus spp.).

Leoni G, De Poli A, Mardirossian M, Gambato S, Florian F, Venier P, Wilson DN, Tossi A, Pallavicini A, Gerdol M.

Mar Drugs. 2017 Aug 22;15(8). pii: E261. doi: 10.3390/md15080261.

12.

Evaluation of free or anchored antimicrobial peptides as candidates for the prevention of orthopaedic device-related infections.

D'Este F, Oro D, Boix-Lemonche G, Tossi A, Skerlavaj B.

J Pept Sci. 2017 Oct;23(10):777-789. doi: 10.1002/psc.3026. Epub 2017 Jul 14.

PMID:
28707817
13.

Tools for Designing Amphipathic Helical Antimicrobial Peptides.

Juretić D, Vukičević D, Tossi A.

Methods Mol Biol. 2017;1548:23-34. doi: 10.1007/978-1-4939-6737-7_2.

PMID:
28013494
14.

PGLa-H tandem-repeat peptides active against multidrug resistant clinical bacterial isolates.

Rončević T, Gajski G, Ilić N, Goić-Barišić I, Tonkić M, Zoranić L, Simunić J, Benincasa M, Mijaković M, Tossi A, Juretić D.

Biochim Biophys Acta Biomembr. 2017 Feb;1859(2):228-237. doi: 10.1016/j.bbamem.2016.11.011. Epub 2016 Nov 24.

15.

Antimicrobial and host cell-directed activities of Gly/Ser-rich peptides from salmonid cathelicidins.

D'Este F, Benincasa M, Cannone G, Furlan M, Scarsini M, Volpatti D, Gennaro R, Tossi A, Skerlavaj B, Scocchi M.

Fish Shellfish Immunol. 2016 Dec;59:456-468. doi: 10.1016/j.fsi.2016.11.004. Epub 2016 Nov 3.

PMID:
27818338
16.

Biofilms from Klebsiella pneumoniae: Matrix Polysaccharide Structure and Interactions with Antimicrobial Peptides.

Benincasa M, Lagatolla C, Dolzani L, Milan A, Pacor S, Liut G, Tossi A, Cescutti P, Rizzo R.

Microorganisms. 2016 Aug 10;4(3). pii: E26. doi: 10.3390/microorganisms4030026.

17.

Identification of antibacterial peptides from endophytic microbiome.

Tejesvi MV, Picart P, Kajula M, Hautajärvi H, Ruddock L, Kristensen HH, Tossi A, Sahl HG, Ek S, Mattila S, Pirttilä AM.

Appl Microbiol Biotechnol. 2016 Nov;100(21):9283-9293. Epub 2016 Aug 19.

PMID:
27541748
18.

The human cathelicidin LL-37--A pore-forming antibacterial peptide and host-cell modulator.

Xhindoli D, Pacor S, Benincasa M, Scocchi M, Gennaro R, Tossi A.

Biochim Biophys Acta. 2016 Mar;1858(3):546-66. doi: 10.1016/j.bbamem.2015.11.003. Epub 2015 Nov 10. Review.

19.

Predicting the Minimal Inhibitory Concentration for Antimicrobial Peptides with Rana-Box Domain.

Kozić M, Vukičević D, Simunić J, Rončević T, Antcheva N, Tossi A, Juretić D.

J Chem Inf Model. 2015 Oct 26;55(10):2275-87. doi: 10.1021/acs.jcim.5b00161. Epub 2015 Sep 18.

PMID:
26332863
20.

Lipopolysaccharide Phosphorylation by the WaaY Kinase Affects the Susceptibility of Escherichia coli to the Human Antimicrobial Peptide LL-37.

Bociek K, Ferluga S, Mardirossian M, Benincasa M, Tossi A, Gennaro R, Scocchi M.

J Biol Chem. 2015 Aug 7;290(32):19933-41. doi: 10.1074/jbc.M114.634758. Epub 2015 Jun 22.

21.

Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7.

Guida F, Benincasa M, Zahariev S, Scocchi M, Berti F, Gennaro R, Tossi A.

J Med Chem. 2015 Feb 12;58(3):1195-204. doi: 10.1021/jm501367p. Epub 2015 Jan 14.

PMID:
25525837
22.

New aspects of the structure and mode of action of the human cathelicidin LL-37 revealed by the intrinsic probe p-cyanophenylalanine.

Xhindoli D, Morgera F, Zinth U, Rizzo R, Pacor S, Tossi A.

Biochem J. 2015 Feb 1;465(3):443-57. doi: 10.1042/BJ20141016.

PMID:
25378136
23.
24.

Native oligomerization determines the mode of action and biological activities of human cathelicidin LL-37.

Xhindoli D, Pacor S, Guida F, Antcheva N, Tossi A.

Biochem J. 2014 Jan 15;457(2):263-75. doi: 10.1042/BJ20131048.

PMID:
24117320
25.

An albumin-derived peptide scaffold capable of binding and catalysis.

Luisi I, Pavan S, Fontanive G, Tossi A, Benedetti F, Savoini A, Maurizio E, Sgarra R, Sblattero D, Berti F.

PLoS One. 2013;8(2):e56469. doi: 10.1371/journal.pone.0056469. Epub 2013 Feb 22.

26.

Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences.

Ilić N, Novković M, Guida F, Xhindoli D, Benincasa M, Tossi A, Juretić D.

Biochim Biophys Acta. 2013 Mar;1828(3):1004-12. doi: 10.1016/j.bbamem.2012.11.017. Epub 2012 Nov 27.

27.

DADP: the database of anuran defense peptides.

Novković M, Simunić J, Bojović V, Tossi A, Juretić D.

Bioinformatics. 2012 May 15;28(10):1406-7. doi: 10.1093/bioinformatics/bts141. Epub 2012 Mar 29.

PMID:
22467909
28.

Synthesis and biological activity of potent HIV-1 protease inhibitors based on Phe-Pro dihydroxyethylene isosteres.

Benedetti F, Berti F, Budal S, Campaner P, Dinon F, Tossi A, Argirova R, Genova P, Atanassov V, Hinkov A.

J Med Chem. 2012 Apr 26;55(8):3900-10. doi: 10.1021/jm3001136. Epub 2012 Apr 17.

PMID:
22458611
29.

Designing Short Peptides with High Affinity for Organic Molecules: A Combined Docking, Molecular Dynamics, And Monte Carlo Approach.

Hong Enriquez RP, Pavan S, Benedetti F, Tossi A, Savoini A, Berti F, Laio A.

J Chem Theory Comput. 2012 Mar 13;8(3):1121-8. doi: 10.1021/ct200873y. Epub 2012 Feb 28.

PMID:
26593371
30.

Identification of antimicrobial peptides from teleosts and anurans in expressed sequence tag databases using conserved signal sequences.

Tessera V, Guida F, Juretić D, Tossi A.

FEBS J. 2012 Mar;279(5):724-36. doi: 10.1111/j.1742-4658.2011.08463.x. Epub 2012 Jan 13.

31.

Comparative activity and mechanism of action of three types of bovine antimicrobial peptides against pathogenic Prototheca spp.

Tomasinsig L, Skerlavaj B, Scarsini M, Guida F, Piccinini R, Tossi A, Zanetti M.

J Pept Sci. 2012 Feb;18(2):105-13. doi: 10.1002/psc.1422. Epub 2011 Nov 14.

PMID:
22083804
32.

Use of unnatural amino acids to probe structure-activity relationships and mode-of-action of antimicrobial peptides.

Tossi A, Scocchi M, Zahariev S, Gennaro R.

Methods Mol Biol. 2012;794:169-83. doi: 10.1007/978-1-61779-331-8_10.

PMID:
21956562
33.

Proline-rich antimicrobial peptides: converging to a non-lytic mechanism of action.

Scocchi M, Tossi A, Gennaro R.

Cell Mol Life Sci. 2011 Jul;68(13):2317-30. doi: 10.1007/s00018-011-0721-7. Epub 2011 May 19. Review.

PMID:
21594684
34.

Effects on antigen-presenting cells of short-term interaction with the human host defence peptide β-defensin 2.

Morgera F, Pacor S, Creatti L, Antcheva N, Vaccari L, Tossi A.

Biochem J. 2011 Jun 15;436(3):537-46. doi: 10.1042/BJ20101977.

PMID:
21434867
35.

Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides.

Juretić D, Vukičević D, Petrov D, Novković M, Bojović V, Lučić B, Ilić N, Tossi A.

Eur Biophys J. 2011 Apr;40(4):371-85. doi: 10.1007/s00249-011-0674-7. Epub 2011 Jan 28.

PMID:
21274708
36.

Histatins in non-human primates: gene variations and functional effects.

Padovan L, Segat L, Pontillo A, Antcheva N, Tossi A, Crovella S.

Protein Pept Lett. 2010 Jul;17(7):909-18.

PMID:
20423320
37.

Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci.

Sass V, Schneider T, Wilmes M, Körner C, Tossi A, Novikova N, Shamova O, Sahl HG.

Infect Immun. 2010 Jun;78(6):2793-800. doi: 10.1128/IAI.00688-09. Epub 2010 Apr 12.

38.

Characterization of a new defensin from cowpea (Vigna unguiculata (L.) Walp.).

Padovan L, Segat L, Tossi A, Calsa T Jr, Ederson AK, Brandao L, Guimarães RL, Pandolfi V, Pestana-Calsa MC, Belarmino LC, Benko-Iseppon AM, Crovella S.

Protein Pept Lett. 2010 Mar;17(3):297-304.

PMID:
20236084
39.

Role of Cathelicidin Peptides in Bovine Host Defense and Healing.

Tomasinsig L, Benincasa M, Scocchi M, Skerlavaj B, Tossi A, Zanetti M, Gennaro R.

Probiotics Antimicrob Proteins. 2010 Mar;2(1):12-20. doi: 10.1007/s12602-010-9035-6.

PMID:
26780897
40.

Broad-spectrum activity against bacterial mastitis pathogens and activation of mammary epithelial cells support a protective role of neutrophil cathelicidins in bovine mastitis.

Tomasinsig L, De Conti G, Skerlavaj B, Piccinini R, Mazzilli M, D'Este F, Tossi A, Zanetti M.

Infect Immun. 2010 Apr;78(4):1781-8. doi: 10.1128/IAI.01090-09. Epub 2010 Jan 25.

41.

Overview on plant antimicrobial peptides.

Benko-Iseppon AM, Galdino SL, Calsa T Jr, Kido EA, Tossi A, Belarmino LC, Crovella S.

Curr Protein Pept Sci. 2010 May;11(3):181-8. Review.

PMID:
20088772
42.

Techniques for plant defensin production.

Padovan L, Crovella S, Tossi A, Segat L.

Curr Protein Pept Sci. 2010 May;11(3):231-5. Review.

PMID:
20088770
43.

Structural aspects of plant antimicrobial peptides.

Padovan L, Scocchi M, Tossi A.

Curr Protein Pept Sci. 2010 May;11(3):210-9. Review.

PMID:
20088769
44.

Computational design of highly selective antimicrobial peptides.

Juretić D, Vukicević D, Ilić N, Antcheva N, Tossi A.

J Chem Inf Model. 2009 Dec;49(12):2873-82. doi: 10.1021/ci900327a.

PMID:
19947578
45.

Structure dependence of biological activities for primate cathelicidins.

Tomasinsig L, Morgera F, Antcheva N, Pacor S, Skerlavaj B, Zanetti M, Tossi A.

J Pept Sci. 2009 Sep;15(9):576-82. doi: 10.1002/psc.1143.

PMID:
19472166
46.

Artificial beta-defensin based on a minimal defensin template.

Antcheva N, Morgera F, Creatti L, Vaccari L, Pag U, Pacor S, Shai Y, Sahl HG, Tossi A.

Biochem J. 2009 Jul 15;421(3):435-47. doi: 10.1042/BJ20082242.

PMID:
19453294
47.

Inhibition of cathelicidin activity by bacterial exopolysaccharides.

Foschiatti M, Cescutti P, Tossi A, Rizzo R.

Mol Microbiol. 2009 Jun;72(5):1137-46. doi: 10.1111/j.1365-2958.2009.06707.x. Epub 2009 Apr 21.

48.

A plant-defensin from sugarcane (Saccharum spp.).

Padovan L, Segat L, Tossi A, Antcheva N, Benko-Iseppon AM, Ederson AK, Brandao L, Calsa T Jr, Crovella S.

Protein Pept Lett. 2009;16(4):430-6.

PMID:
19356142
49.

Primate cathelicidin orthologues display different structures and membrane interactions.

Morgera F, Vaccari L, Antcheva N, Scaini D, Pacor S, Tossi A.

Biochem J. 2009 Feb 1;417(3):727-35. doi: 10.1042/BJ20081726.

PMID:
18922132
50.

The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.

Tomasinsig L, Pizzirani C, Skerlavaj B, Pellegatti P, Gulinelli S, Tossi A, Di Virgilio F, Zanetti M.

J Biol Chem. 2008 Nov 7;283(45):30471-81. doi: 10.1074/jbc.M802185200. Epub 2008 Sep 2.

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