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Items: 46

1.

MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors.

Lutzmann M, Bernex F, da Costa de Jesus C, Hodroj D, Marty C, Plo I, Vainchenker W, Tosolini M, Forichon L, Bret C, Queille S, Marchive C, Hoffmann JS, Méchali M.

Cell Rep. 2019 Sep 10;28(11):2851-2865.e4. doi: 10.1016/j.celrep.2019.07.095.

2.

A Tridimensional Model for NK Cell-Mediated ADCC of Follicular Lymphoma.

Decaup E, Rossi C, Gravelle P, Laurent C, Bordenave J, Tosolini M, Tourette A, Perrial E, Dumontet C, Poupot M, Klein C, Savina A, Fournié JJ, Bezombes C.

Front Immunol. 2019 Aug 14;10:1943. doi: 10.3389/fimmu.2019.01943. eCollection 2019.

3.

GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.

Mondragón L, Mhaidly R, De Donatis GM, Tosolini M, Dao P, Martin AR, Pons C, Chiche J, Jacquin M, Imbert V, Proïcs E, Boyer L, Doye A, Luciano F, Neels JG, Coutant F, Fabien N, Sormani L, Rubio-Patiño C, Bossowski JP, Muller F, Marchetti S, Villa E, Peyron JF, Gaulard P, Lemonnier F, Asnafi V, Genestier L, Benhida R, Fournié JJ, Passeron T, Ricci JE, Verhoeyen E.

Cancer Cell. 2019 Sep 16;36(3):268-287.e10. doi: 10.1016/j.ccell.2019.07.008. Epub 2019 Aug 22.

PMID:
31447347
4.

Single-Cell Signature Explorer for comprehensive visualization of single cell signatures across scRNA-seq datasets.

Pont F, Tosolini M, Fournié JJ.

Nucleic Acids Res. 2019 Jul 11. pii: gkz601. doi: 10.1093/nar/gkz601. [Epub ahead of print]

PMID:
31294801
5.

Feasibility of a multidisciplinary approach for medical review among elderly patients in four Italian long-term nursing homes.

Cattaruzzi C, Cadelli L, Marcuzzo L, Antonini A, Groppo B, Ros B, Tosolini M, Lemessi N.

Eur J Hosp Pharm. 2018 Jul;25(4):207-209. doi: 10.1136/ejhpharm-2015-000812. Epub 2016 May 24.

6.

Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes.

Pizzolato G, Kaminski H, Tosolini M, Franchini DM, Pont F, Martins F, Valle C, Labourdette D, Cadot S, Quillet-Mary A, Poupot M, Laurent C, Ysebaert L, Meraviglia S, Dieli F, Merville P, Milpied P, Déchanet-Merville J, Fournié JJ.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11906-11915. doi: 10.1073/pnas.1818488116. Epub 2019 May 22.

PMID:
31118283
7.

PTMselect: optimization of protein modifications discovery by mass spectrometry.

Perchey RT, Tonini L, Tosolini M, Fournié JJ, Lopez F, Besson A, Pont F.

Sci Rep. 2019 Mar 12;9(1):4181. doi: 10.1038/s41598-019-40873-3.

8.

Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma.

Rossi C, Gravelle P, Decaup E, Bordenave J, Poupot M, Tosolini M, Franchini DM, Laurent C, Morin R, Lagarde JM, Ysebaert L, Ligat L, Jean C, Savina A, Klein C, Céspedes AM, Perez-Galan P, Fournié JJ, Bezombes C.

Oncoimmunology. 2018 Dec 17;8(3):1554175. doi: 10.1080/2162402X.2018.1554175. eCollection 2019.

PMID:
30723586
9.

Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells.

Franchini DM, Lanvin O, Tosolini M, Patras de Campaigno E, Cammas A, Péricart S, Scarlata CM, Lebras M, Rossi C, Ligat L, Pont F, Arimondo PB, Laurent C, Ayyoub M, Despas F, Lapeyre-Mestre M, Millevoi S, Fournié JJ.

Cell Rep. 2019 Jan 2;26(1):94-107.e7. doi: 10.1016/j.celrep.2018.12.014.

10.

Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma.

Neuzillet C, Tijeras-Raballand A, Ragulan C, Cros J, Patil Y, Martinet M, Erkan M, Kleeff J, Wilson J, Apte M, Tosolini M, Wilson AS, Delvecchio FR, Bousquet C, Paradis V, Hammel P, Sadanandam A, Kocher HM.

J Pathol. 2019 May;248(1):51-65. doi: 10.1002/path.5224. Epub 2019 Feb 22.

11.

Profiling Immune Escape in Hodgkin's and Diffuse large B-Cell Lymphomas Using the Transcriptome and Immunostaining.

Péricart S, Tosolini M, Gravelle P, Rossi C, Traverse-Glehen A, Amara N, Franchet C, Martin E, Bezombes C, Laurent G, Brousset P, Fournié JJ, Laurent C.

Cancers (Basel). 2018 Oct 31;10(11). pii: E415. doi: 10.3390/cancers10110415.

12.

RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma.

Boyrie S, Delmas C, Lemarié A, Lubrano V, Dahan P, Malric L, Luis J, Gilhodes J, Tosolini M, Mouly L, Lehmann M, Toulas C, Cohen-Jonathan Moyal E, Monferran S.

Oncotarget. 2018 Sep 18;9(73):33788-33803. doi: 10.18632/oncotarget.26082. eCollection 2018 Sep 18.

13.

EBV infection determines the immune hallmarks of plasmablastic lymphoma.

Gravelle P, Péricart S, Tosolini M, Fabiani B, Coppo P, Amara N, Traverse-Gléhen A, Van Acker N, Brousset P, Fournie JJ, Laurent C.

Oncoimmunology. 2018 Jul 30;7(10):e1486950. doi: 10.1080/2162402X.2018.1486950. eCollection 2018.

14.

Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids.

Schettini R, Costabile C, Della Sala G, Buirey J, Tosolini M, Tecilla P, Vaccaro MC, Bruno I, De Riccardis F, Izzo I.

Org Biomol Chem. 2018 Sep 19;16(36):6708-6717. doi: 10.1039/c8ob01522h.

PMID:
30182115
15.

Contrasting epigenetic states of heterochromatin in the different types of mouse pluripotent stem cells.

Tosolini M, Brochard V, Adenot P, Chebrout M, Grillo G, Navia V, Beaujean N, Francastel C, Bonnet-Garnier A, Jouneau A.

Sci Rep. 2018 Apr 10;8(1):5776. doi: 10.1038/s41598-018-23822-4.

16.

Biological Activity of Trans-Membrane Anion Carriers.

Tosolini M, Pengo P, Tecilla P.

Curr Med Chem. 2018;25(30):3560-3576. doi: 10.2174/0929867325666180309113222. Review.

PMID:
29521206
17.

Dendrogenin A drives LXR to trigger lethal autophagy in cancers.

Segala G, David M, de Medina P, Poirot MC, Serhan N, Vergez F, Mougel A, Saland E, Carayon K, Leignadier J, Caron N, Voisin M, Cherier J, Ligat L, Lopez F, Noguer E, Rives A, Payré B, Saati TA, Lamaziere A, Despres G, Lobaccaro JM, Baron S, Demur C, de Toni F, Larrue C, Boutzen H, Thomas F, Sarry JE, Tosolini M, Picard D, Record M, Récher C, Poirot M, Silvente-Poirot S.

Nat Commun. 2017 Dec 4;8(1):1903. doi: 10.1038/s41467-017-01948-9.

18.

Distinctive features of tumor-infiltrating γδ T lymphocytes in human colorectal cancer.

Meraviglia S, Lo Presti E, Tosolini M, La Mendola C, Orlando V, Todaro M, Catalano V, Stassi G, Cicero G, Vieni S, Fourniè JJ, Dieli F.

Oncoimmunology. 2017 Jul 13;6(10):e1347742. doi: 10.1080/2162402X.2017.1347742. eCollection 2017.

19.

Nurse-like cells promote CLL survival through LFA-3/CD2 interactions.

Boissard F, Tosolini M, Ligat L, Quillet-Mary A, Lopez F, Fournié JJ, Ysebaert L, Poupot M.

Oncotarget. 2016 Nov 26;8(32):52225-52236. doi: 10.18632/oncotarget.13660. eCollection 2017 Aug 8.

20.

Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties.

D'Amato A, Volpe R, Vaccaro MC, Terracciano S, Bruno I, Tosolini M, Tedesco C, Pierri G, Tecilla P, Costabile C, Della Sala G, Izzo I, De Riccardis F.

J Org Chem. 2017 Sep 1;82(17):8848-8863. doi: 10.1021/acs.joc.7b00965. Epub 2017 Aug 17.

PMID:
28763612
21.

Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients.

De Clara E, Gourvest M, Ma H, Vergez F, Tosolini M, Dejean S, Demur C, Delabesse E, Recher C, Touriol C, Martelli MP, Falini B, Brousset P, Bousquet M.

Haematologica. 2017 Oct;102(10):1718-1726. doi: 10.3324/haematol.2017.171645. Epub 2017 Jul 4.

22.

Assessment of tumor-infiltrating TCRVγ9Vδ2 γδ lymphocyte abundance by deconvolution of human cancers microarrays.

Tosolini M, Pont F, Poupot M, Vergez F, Nicolau-Travers ML, Vermijlen D, Sarry JE, Dieli F, Fournié JJ.

Oncoimmunology. 2017 Feb 6;6(3):e1284723. doi: 10.1080/2162402X.2017.1284723. eCollection 2017.

23.

Mechanisms of PD-1/PD-L1 expression and prognostic relevance in non-Hodgkin lymphoma: a summary of immunohistochemical studies.

Gravelle P, Burroni B, Péricart S, Rossi C, Bezombes C, Tosolini M, Damotte D, Brousset P, Fournié JJ, Laurent C.

Oncotarget. 2017 Jul 4;8(27):44960-44975. doi: 10.18632/oncotarget.16680. Review.

24.

XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.

Vallot C, Patrat C, Collier AJ, Huret C, Casanova M, Liyakat Ali TM, Tosolini M, Frydman N, Heard E, Rugg-Gunn PJ, Rougeulle C.

Cell Stem Cell. 2017 Jan 5;20(1):102-111. doi: 10.1016/j.stem.2016.10.014. Epub 2016 Dec 15.

25.

Synthesis and complexing properties of cyclic benzylopeptoids - a new family of extended macrocyclic peptoids.

Meli A, Gambaro S, Costabile C, Talotta C, Della Sala G, Tecilla P, Milano D, Tosolini M, Izzo I, De Riccardis F.

Org Biomol Chem. 2016 Sep 26;14(38):9055-9062.

PMID:
27714208
26.

Large-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas.

Tosolini M, Algans C, Pont F, Ycart B, Fournié JJ.

Oncoimmunology. 2016 May 19;5(7):e1188246. doi: 10.1080/2162402X.2016.1188246. eCollection 2016 Jul.

27.

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.

Mlecnik B, Bindea G, Kirilovsky A, Angell HK, Obenauf AC, Tosolini M, Church SE, Maby P, Vasaturo A, Angelova M, Fredriksen T, Mauger S, Waldner M, Berger A, Speicher MR, Pagès F, Valge-Archer V, Galon J.

Sci Transl Med. 2016 Feb 24;8(327):327ra26. doi: 10.1126/scitranslmed.aad6352.

PMID:
26912905
28.

Cyclic dinucleotides modulate human T-cell response through monocyte cell death.

Tosolini M, Pont F, Verhoeyen E, Fournié JJ.

Eur J Immunol. 2015 Dec;45(12):3313-23. doi: 10.1002/eji.201545697. Epub 2015 Oct 15.

29.

Several immune escape patterns in non-Hodgkin's lymphomas.

Laurent C, Charmpi K, Gravelle P, Tosolini M, Franchet C, Ysebaert L, Brousset P, Bidaut A, Ycart B, Fournié JJ.

Oncoimmunology. 2015 Apr 2;4(8):e1026530. eCollection 2015 Aug.

30.

From Naive to Primed Pluripotency: In Vitro Conversion of Mouse Embryonic Stem Cells in Epiblast Stem Cells.

Tosolini M, Jouneau A.

Methods Mol Biol. 2016;1341:209-16. doi: 10.1007/7651_2015_208.

PMID:
25720370
31.

Acquiring Ground State Pluripotency: Switching Mouse Embryonic Stem Cells from Serum/LIF Medium to 2i/LIF Medium.

Tosolini M, Jouneau A.

Methods Mol Biol. 2016;1341:41-8. doi: 10.1007/7651_2015_207.

PMID:
25720369
32.

Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death.

Tosolini M, Pont F, Bétous D, Ravet E, Ligat L, Lopez F, Poupot M, Poirot M, Pérouzel É, Tiraby G, Verhoeyen E, Fournié JJ.

Mol Cell Biol. 2015 Jan;35(2):479-95. doi: 10.1128/MCB.01204-14. Epub 2014 Nov 10.

33.

Stable methylation at promoters distinguishes epiblast stem cells from embryonic stem cells and the in vivo epiblasts.

Veillard AC, Marks H, Bernardo AS, Jouneau L, Laloë D, Boulanger L, Kaan A, Brochard V, Tosolini M, Pedersen R, Stunnenberg H, Jouneau A.

Stem Cells Dev. 2014 Sep 1;23(17):2014-29. doi: 10.1089/scd.2013.0639. Epub 2014 Jun 12.

34.

Functional network pipeline reveals genetic determinants associated with in situ lymphocyte proliferation and survival of cancer patients.

Mlecnik B, Bindea G, Angell HK, Sasso MS, Obenauf AC, Fredriksen T, Lafontaine L, Bilocq AM, Kirilovsky A, Tosolini M, Waldner M, Berger A, Fridman WH, Rafii A, Valge-Archer V, Pagès F, Speicher MR, Galon J.

Sci Transl Med. 2014 Mar 19;6(228):228ra37. doi: 10.1126/scitranslmed.3007240.

35.

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Bindea G, Mlecnik B, Tosolini M, Kirilovsky A, Waldner M, Obenauf AC, Angell H, Fredriksen T, Lafontaine L, Berger A, Bruneval P, Fridman WH, Becker C, Pagès F, Speicher MR, Trajanoski Z, Galon J.

Immunity. 2013 Oct 17;39(4):782-95. doi: 10.1016/j.immuni.2013.10.003.

36.

Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer.

Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G, Berger A, Bruneval P, Fridman WH, Pagès F, Galon J.

Cancer Res. 2011 Feb 15;71(4):1263-71. doi: 10.1158/0008-5472.CAN-10-2907. Epub 2011 Feb 8. Erratum in: Cancer Res. 2011 Jul 1;71(13):4732.

37.

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.

Mlecnik B, Tosolini M, Kirilovsky A, Berger A, Bindea G, Meatchi T, Bruneval P, Trajanoski Z, Fridman WH, Pagès F, Galon J.

J Clin Oncol. 2011 Feb 20;29(6):610-8. doi: 10.1200/JCO.2010.30.5425. Epub 2011 Jan 18.

PMID:
21245428
38.

Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.

Mlecnik B, Tosolini M, Charoentong P, Kirilovsky A, Bindea G, Berger A, Camus M, Gillard M, Bruneval P, Fridman WH, Pagès F, Trajanoski Z, Galon J.

Gastroenterology. 2010 Apr;138(4):1429-40. doi: 10.1053/j.gastro.2009.10.057. Epub 2009 Nov 10.

PMID:
19909745
39.

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

Pagès F, Kirilovsky A, Mlecnik B, Asslaber M, Tosolini M, Bindea G, Lagorce C, Wind P, Marliot F, Bruneval P, Zatloukal K, Trajanoski Z, Berger A, Fridman WH, Galon J.

J Clin Oncol. 2009 Dec 10;27(35):5944-51. doi: 10.1200/JCO.2008.19.6147. Epub 2009 Oct 26.

PMID:
19858404
40.

FOXP3-enriched infiltrates associated with better outcome in renal allografts with inflamed fibrosis.

Zuber J, Brodin-Sartorius A, Lapidus N, Patey N, Tosolini M, Candon S, Rabant M, Snanoudj R, Panterne C, Thervet E, Legendre C, Chatenoud L.

Nephrol Dial Transplant. 2009 Dec;24(12):3847-54. doi: 10.1093/ndt/gfp435. Epub 2009 Sep 3.

PMID:
19729462
41.

Coordination of intratumoral immune reaction and human colorectal cancer recurrence.

Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman WH, Galon J.

Cancer Res. 2009 Mar 15;69(6):2685-93. doi: 10.1158/0008-5472.CAN-08-2654. Epub 2009 Mar 3.

42.

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.

Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman WH, Pagès F, Trajanoski Z, Galon J.

Bioinformatics. 2009 Apr 15;25(8):1091-3. doi: 10.1093/bioinformatics/btp101. Epub 2009 Feb 23.

43.

Drug waste minimisation and cost-containment in Medical Oncology: two-year results of a feasibility study.

Fasola G, Aita M, Marini L, Follador A, Tosolini M, Mattioni L, Mansutti M, Piga A, Brusaferro S, Aprile G.

BMC Health Serv Res. 2008 Apr 1;8:70. doi: 10.1186/1472-6963-8-70.

44.

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome.

Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pagès C, Tosolini M, Camus M, Berger A, Wind P, Zinzindohoué F, Bruneval P, Cugnenc PH, Trajanoski Z, Fridman WH, Pagès F.

Science. 2006 Sep 29;313(5795):1960-4.

45.

Albumin and fibrinogen synthesis and insulin effect in type 2 diabetic patients with normoalbuminuria.

Tessari P, Kiwanuka E, Millioni R, Vettore M, Puricelli L, Zanetti M, Gucciardi A, Tosolini M, Cogo P, Carnielli V, Tiengo A, Barazzoni R.

Diabetes Care. 2006 Feb;29(2):323-8.

PMID:
16443881
46.

Plasma protein synthesis in patients with low-grade nephrotic proteinuria.

Zanetti M, Barazzoni R, Garibotto G, Davanzo G, Gabelli C, Kiwanuka E, Piccoli A, Tosolini M, Tessari P.

Am J Physiol Endocrinol Metab. 2001 Apr;280(4):E591-7.

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