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Items: 35

1.
2.

Ocular Gene Therapy-The Future Is Now.

Huang SS, High K, Toso R.

Asia Pac J Ophthalmol (Phila). 2016 Jul-Aug;5(4):227-8. doi: 10.1097/APO.0000000000000216. No abstract available.

PMID:
27488063
3.

Risk Management in Biologics Technology Transfer.

Toso R, Tsang J, Xie J, Hohwald S, Bain D, Willison-Parry D.

PDA J Pharm Sci Technol. 2016 11/12;70(6):596-599. Epub 2016 Jun 20.

PMID:
27325596
4.

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice.

Liang HP, Kerschen EJ, Basu S, Hernandez I, Zogg M, Jia S, Hessner MJ, Toso R, Rezaie AR, Fernández JA, Camire RM, Ruf W, Griffin JH, Weiler H.

Blood. 2015 Nov 19;126(21):2415-23. doi: 10.1182/blood-2015-05-644401. Epub 2015 Sep 4. Erratum in: Blood. 2018 May 31;131(22):2509.

5.

Biased Random-Key Genetic Algorithms for the Winner Determination Problem in Combinatorial Auctions.

de Andrade CE, Toso RF, Resende MG, Miyazawa FK.

Evol Comput. 2015 Summer;23(2):279-307. doi: 10.1162/EVCO_a_00138. Epub 2014 Oct 9.

PMID:
25299242
6.
7.

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.

Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, Liu JH, Clerin V, Pittman DD, Rose-Miranda R, Shields KM, Erbe DV, Tobin JF, Arruda VR, Camire RM.

Nat Biotechnol. 2011 Oct 23;29(11):1028-33. doi: 10.1038/nbt.1995.

8.

Effects of verbascoside, biotechnologically purified by Syringa vulgaris plant cell cultures, in a rodent model of periodontitis.

Paola RD, Oteri G, Mazzon E, Crisafulli C, Galuppo M, Toso RD, Pressi G, Cordasco G, Cuzzocrea S.

J Pharm Pharmacol. 2011 May;63(5):707-17. doi: 10.1111/j.2042-7158.2011.01262.x. Epub 2011 Apr 1.

PMID:
21492173
9.

Zymogen-like factor Xa variants restore thrombin generation and effectively bypass the intrinsic pathway in vitro.

Bunce MW, Toso R, Camire RM.

Blood. 2011 Jan 6;117(1):290-8. doi: 10.1182/blood-2010-08-300756. Epub 2010 Sep 23.

10.

3,5-Dicaffeoyl-4-malonylquinic acid reduced oxidative stress and inflammation in a experimental model of inflammatory bowel disease.

di Paola R, Esposito E, Mazzon E, Caminiti R, Toso RD, Pressi G, Cozzocrea S.

Free Radic Res. 2010 Jan;44(1):74-89. doi: 10.3109/10715760903300709.

PMID:
19886745
11.

Recombinant canine B-domain-deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model.

Sabatino DE, Freguia CF, Toso R, Santos A, Merricks EP, Kazazian HH Jr, Nichols TC, Camire RM, Arruda VR.

Blood. 2009 Nov 12;114(20):4562-5. doi: 10.1182/blood-2009-05-220327. Epub 2009 Sep 21.

12.

The conformational switch from the factor X zymogen to protease state mediates exosite expression and prothrombinase assembly.

Toso R, Zhu H, Camire RM.

J Biol Chem. 2008 Jul 4;283(27):18627-35. doi: 10.1074/jbc.M802205200. Epub 2008 May 6.

13.

Inhibitory sequences within the B-domain stabilize circulating factor V in an inactive state.

Zhu H, Toso R, Camire RM.

J Biol Chem. 2007 May 18;282(20):15033-9. Epub 2007 Mar 26.

14.

Role of Hirudin-like factor Va heavy chain sequences in prothrombinase function.

Toso R, Camire RM.

J Biol Chem. 2006 Mar 31;281(13):8773-9. Epub 2006 Jan 23.

15.

Factor V Leiden improves in vivo hemostasis in murine hemophilia models.

Schlachterman A, Schuettrumpf J, Liu JH, Furlan Freguia C, Toso R, Poncz M, Camire RM, Arruda VR.

J Thromb Haemost. 2005 Dec;3(12):2730-7. Erratum in: J Thromb Haemost. 2006 Apr;4(4):925. Freguia, CF [corrected to Furlan Freguia, C].

16.

Characterization of mild coagulation factor VII deficiency: activity and clearance of the Arg315Trp and Arg315Lys variants in the Cys310-Cys329 loop (c170s).

Furlan Freguia C, Toso R, Pollak ES, Arruda VR, Pinotti M, Bernardi F.

Haematologica. 2004 Dec;89(12):1504-9.

17.
18.

Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency.

Furlan Freguia C, Toso R, Ferraresi P, Pinotti M, Bernardi F.

Thromb Haemost. 2003 Dec;90(6):1220-2. No abstract available.

PMID:
14652663
19.

Comparison among natural (Arg304Gln, Arg304Trp) and artificial (Arg290His, Arg290Lys) mutations in coagulation factor VII loops.

Furlan Freguia C, Toso R, Pinotti M, Gemmati D, Bernardi F.

J Thromb Haemost. 2003 Nov;1(11):2455-7. No abstract available.

20.

Factor VII mutant V154G models a zymogen-like form of factor VIIa.

Toso R, Bernardi F, Tidd T, Pinotti M, Camire RM, Marchetti G, High KA, Pollak ES.

Biochem J. 2003 Feb 1;369(Pt 3):563-71.

21.
22.

Modulation of factor VII levels by intron 7 polymorphisms: population and in vitro studies.

Pinotti M, Toso R, Girelli D, Bindini D, Ferraresi P, Papa ML, Corrocher R, Marchetti G, Bernardi F.

Blood. 2000 Jun 1;95(11):3423-8.

PMID:
10828024
23.

Molecular mechanisms of FVII deficiency: expression of mutations clustered in the IVS7 donor splice site of factor VII gene.

Pinotti M, Toso R, Redaelli R, Berrettini M, Marchetti G, Bernardi F.

Blood. 1998 Sep 1;92(5):1646-51.

PMID:
9716592
24.

Interactions between brain-derived neurotrophic factor and the TRKB receptor. Identification of two ligand binding domains in soluble TRKB by affinity separation and chemical cross-linking.

Haniu M, Montestruque S, Bures EJ, Talvenheimo J, Toso R, Lewis-Sandy S, Welcher AA, Rohde MF.

J Biol Chem. 1997 Oct 3;272(40):25296-303.

25.

The majority of stem cell factor exists as monomer under physiological conditions. Implications for dimerization mediating biological activity.

Hsu YR, Wu GM, Mendiaz EA, Syed R, Wypych J, Toso R, Mann MB, Boone TC, Narhi LO, Lu HS, Langley KE.

J Biol Chem. 1997 Mar 7;272(10):6406-15.

26.

B61, a ligand for the Eck receptor protein-tyrosine kinase, exhibits neurotrophic activity in cultures of rat spinal cord neurons.

Magal E, Holash JA, Toso RJ, Chang D, Lindberg RA, Pasquale EB.

J Neurosci Res. 1996 Mar 15;43(6):735-44.

PMID:
8984203
27.

Commercial [3H]glutamate contains a contaminant that labels tubulin covalently.

Gupta ML, Toso RJ, Farrell KW, Wilson L, Himes RH.

Anal Biochem. 1995 Sep 20;230(2):350-3. No abstract available.

PMID:
7503431
28.

Protein B61 as a new growth factor: expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression.

Easty DJ, Guthrie BA, Maung K, Farr CJ, Lindberg RA, Toso RJ, Herlyn M, Bennett DC.

Cancer Res. 1995 Jun 15;55(12):2528-32.

29.

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6.

Varnum BC, Young C, Elliott G, Garcia A, Bartley TD, Fridell YW, Hunt RW, Trail G, Clogston C, Toso RJ, et al.

Nature. 1995 Feb 16;373(6515):623-6.

PMID:
7854420
30.

Relationship of DNA topoisomerase II alpha and beta expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines.

Brown GA, McPherson JP, Gu L, Hedley DW, Toso R, Deuchars KL, Freedman MH, Goldenberg GJ.

Cancer Res. 1995 Jan 1;55(1):78-82.

31.

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Jordan MA, Toso RJ, Thrower D, Wilson L.

Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9552-6.

32.

Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine.

Toso RJ, Jordan MA, Farrell KW, Matsumoto B, Wilson L.

Biochemistry. 1993 Feb 9;32(5):1285-93.

PMID:
8448138
33.

Improvement of production, assay and purification of streptavidin.

Aldwin L, Toso R, Goodson R, Hunter J.

J Ind Microbiol. 1990 Jun;5(4):239-46.

PMID:
1366608
34.

Synthesis and properties of some new 11-acyl-5,11-dihydro-6H-pyrido [2,3-b] [1,4]-benzodiazepin-6-ones.

Decorte E, Gratton G, Kovac T, Mihalić M, Comisso G, Angeli C, Toso R, Sunjić V.

Farmaco Sci. 1982 Dec;37(12):787-96.

PMID:
7152014
35.

Interaction of cimetidine with liver microsomes.

Rendić S, Sunjić V, Toso R, Kajfez F, Ruf HH.

Xenobiotica. 1979 Sep;9(9):555-64. No abstract available.

PMID:
524915

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