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Items: 42

1.

Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2).

Cocco E, Javier Carmona F, Razavi P, Won HH, Cai Y, Rossi V, Chan C, Cownie J, Soong J, Toska E, Shifman SG, Sarotto I, Savas P, Wick MJ, Papadopoulos KP, Moriarty A, Cutler RE Jr, Avogadri-Connors F, Lalani AS, Bryce RP, Chandarlapaty S, Hyman DM, Solit DB, Boni V, Loi S, Baselga J, Berger MF, Montemurro F, Scaltriti M.

Sci Signal. 2018 Oct 9;11(551). pii: eaat9773. doi: 10.1126/scisignal.aat9773.

PMID:
30301790
2.

STACKing the odds for adolescent survival: health service factors associated with full retention in care and adherence amongst adolescents living with HIV in South Africa.

Cluver L, Pantelic M, Toska E, Orkin M, Casale M, Bungane N, Sherr L.

J Int AIDS Soc. 2018 Sep;21(9):e25176. doi: 10.1002/jia2.25176.

3.

Defining adolescence: priorities from a global health perspective.

Kinghorn A, Shanaube K, Toska E, Cluver L, Bekker LG.

Lancet Child Adolesc Health. 2018 May;2(5):e10. doi: 10.1016/S2352-4642(18)30096-8. Epub 2018 Mar 23. No abstract available.

PMID:
30169271
4.

'Yummy or crummy?' The multisensory components of medicines-taking among HIV-positive youth.

Hodes R, Vale B, Toska E, Cluver L, Dowse R, Ashorn M.

Glob Public Health. 2018 Aug 1:1-16. doi: 10.1080/17441692.2018.1504103. [Epub ahead of print]

PMID:
30067457
5.

Differing psychological vulnerabilities among behaviourally and perinatally HIV infected adolescents in South Africa - implications for targeted health service provision.

Sherr L, Cluver LD, Toska E, He E.

AIDS Care. 2018 Jun;30(sup2):92-101. doi: 10.1080/09540121.2018.1476664. Epub 2018 May 30.

PMID:
29848010
6.

Multitype violence exposures and adolescent antiretroviral nonadherence in South Africa.

Cluver L, Meinck F, Toska E, Orkin FM, Hodes R, Sherr L.

AIDS. 2018 May 15;32(8):975-983. doi: 10.1097/QAD.0000000000001795.

7.

The stuff that dreams are made of: HIV-positive adolescents' aspirations for development.

Hodes R, Doubt J, Toska E, Vale B, Zungu N, Cluver L.

J Int AIDS Soc. 2018 Feb;21 Suppl 1. doi: 10.1002/jia2.25057.

8.

Sustainable Survival for adolescents living with HIV: do SDG-aligned provisions reduce potential mortality risk?

Cluver L, Pantelic M, Orkin M, Toska E, Medley S, Sherr L.

J Int AIDS Soc. 2018 Feb;21 Suppl 1. doi: 10.1002/jia2.25056.

9.

Beyond clinical trials: Cross-sectional associations of combination antiretroviral therapy with reports of multiple symptoms and non-adherence among adolescents in South Africa.

Natukunda HPM, Cluver LD, Toska E, Musiime V, Yakubovich AR.

S Afr Med J. 2017 Oct 31;107(11):965-975. doi: 10.7196/SAMJ.2017.v107i11.12405.

10.

How front-line healthcare workers respond to stock-outs of essential medicines in the Eastern Cape Province of South Africa.

Hodes R, Price I, Bungane N, Toska E, Cluver L.

S Afr Med J. 2017 Aug 25;107(9):738-740. doi: 10.7196/SAMJ.2017.v107i9.12476.

PMID:
28875877
11.

Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations.

Norris SA, Daar A, Balasubramanian D, Byass P, Kimani-Murage E, Macnab A, Pauw C, Singhal A, Yajnik C, Akazili J, Levitt N, Maatoug J, Mkhwanazi N, Moore SE, Nyirenda M, Pulliam JRC, Rochat T, Said-Mohamed R, Seedat S, Sobngwi E, Tomlinson M, Toska E, van Schalkwyk C.

Glob Health Action. 2017;10(1):1334985. doi: 10.1080/16549716.2017.1334985.

12.

Sex in the shadow of HIV: A systematic review of prevalence, risk factors, and interventions to reduce sexual risk-taking among HIV-positive adolescents and youth in sub-Saharan Africa.

Toska E, Pantelic M, Meinck F, Keck K, Haghighat R, Cluver L.

PLoS One. 2017 Jun 5;12(6):e0178106. doi: 10.1371/journal.pone.0178106. eCollection 2017. Review.

13.

Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265 mutations.

Mondello P, Brea EJ, De Stanchina E, Toska E, Chang AY, Fennell M, Seshan V, Garippa R, Scheinberg DA, Baselga J, Wendel HG, Younes A.

JCI Insight. 2017 Mar 23;2(6):e90196. doi: 10.1172/jci.insight.90196.

14.

PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.

Toska E, Osmanbeyoglu HU, Castel P, Chan C, Hendrickson RC, Elkabets M, Dickler MN, Scaltriti M, Leslie CS, Armstrong SA, Baselga J.

Science. 2017 Mar 24;355(6331):1324-1330. doi: 10.1126/science.aah6893.

15.

Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs.

Osmanbeyoglu HU, Toska E, Chan C, Baselga J, Leslie CS.

Nat Commun. 2017 Jan 31;8:14249. doi: 10.1038/ncomms14249.

16.

School, Supervision and Adolescent-Sensitive Clinic Care: Combination Social Protection and Reduced Unprotected Sex Among HIV-Positive Adolescents in South Africa.

Toska E, Cluver LD, Boyes ME, Isaacsohn M, Hodes R, Sherr L.

AIDS Behav. 2017 Sep;21(9):2746-2759. doi: 10.1007/s10461-016-1539-y.

17.

TRI_tool: a web-tool for prediction of protein-protein interactions in human transcriptional regulation.

Perovic V, Sumonja N, Gemovic B, Toska E, Roberts SG, Veljkovic N.

Bioinformatics. 2017 Jan 15;33(2):289-291. doi: 10.1093/bioinformatics/btw590. Epub 2016 Sep 7.

PMID:
27605104
18.

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition.

Castel P, Ellis H, Bago R, Toska E, Razavi P, Carmona FJ, Kannan S, Verma CS, Dickler M, Chandarlapaty S, Brogi E, Alessi DR, Baselga J, Scaltriti M.

Cancer Cell. 2016 Aug 8;30(2):229-242. doi: 10.1016/j.ccell.2016.06.004. Epub 2016 Jul 21.

19.

Resourcing resilience: social protection for HIV prevention amongst children and adolescents in Eastern and Southern Africa.

Toska E, Gittings L, Hodes R, Cluver LD, Govender K, Chademana KE, Gutiérrez VE.

Afr J AIDS Res. 2016 Jul;15(2):123-40. doi: 10.2989/16085906.2016.1194299. Review. Erratum in: Afr J AIDS Res. 2016 Sep;15(3):314.

20.

Achieving equity in HIV-treatment outcomes: can social protection improve adolescent ART-adherence in South Africa?

Cluver LD, Toska E, Orkin FM, Meinck F, Hodes R, Yakubovich AR, Sherr L.

AIDS Care. 2016 Mar;28 Suppl 2:73-82. doi: 10.1080/09540121.2016.1179008.

21.

Pharmacology in the Era of Targeted Therapies: The Case of PI3K Inhibitors.

Toska E, Baselga J.

Clin Cancer Res. 2016 May 1;22(9):2099-101. doi: 10.1158/1078-0432.CCR-16-0038. Epub 2016 Mar 8.

22.

Sex and secrecy: How HIV-status disclosure affects safe sex among HIV-positive adolescents.

Toska E, Cluver LD, Hodes R, Kidia KK.

AIDS Care. 2015;27 Suppl 1:47-58. doi: 10.1080/09540121.2015.1071775.

23.

Use of transvaginal ultrasound in females with primary bladder neck obstruction. A preliminary study.

Galica V, Toska E, Saldutto P, Galatioto GP, Vicentini C.

Arch Ital Urol Androl. 2015 Jul 7;87(2):158-60. doi: 10.4081/aiua.2015.2.158.

24.

'HIV is like a tsotsi. ARVs are your guns': associations between HIV-disclosure and adherence to antiretroviral treatment among adolescents in South Africa.

Cluver LD, Hodes RJ, Toska E, Kidia KK, Orkin FM, Sherr L, Meinck F.

AIDS. 2015 Jun;29 Suppl 1:S57-65. doi: 10.1097/QAD.0000000000000695.

PMID:
26049539
25.
26.

PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer.

Bosch A, Li Z, Bergamaschi A, Ellis H, Toska E, Prat A, Tao JJ, Spratt DE, Viola-Villegas NT, Castel P, Minuesa G, Morse N, Rodón J, Ibrahim Y, Cortes J, Perez-Garcia J, Galvan P, Grueso J, Guzman M, Katzenellenbogen JA, Kharas M, Lewis JS, Dickler M, Serra V, Rosen N, Chandarlapaty S, Scaltriti M, Baselga J.

Sci Transl Med. 2015 Apr 15;7(283):283ra51. doi: 10.1126/scitranslmed.aaa4442.

27.
28.

Multiplex PCR assay for the rapid identification of human papillomavirus genotypes 16, 18, 45, 35, 66, 33, 51, 58, and 31 in clinical samples.

Tsakogiannis D, Diamantidou V, Toska E, Kyriakopoulou Z, Dimitriou TG, Ruether IG, Gortsilas P, Markoulatos P.

Arch Virol. 2015 Jan;160(1):207-14. doi: 10.1007/s00705-014-2261-6. Epub 2014 Oct 25.

PMID:
25344303
29.

Duplex Real-time PCR assay and SYBR green I melting curve analysis for molecular identification of HPV genotypes 16, 18, 31, 35, 51 and 66.

Tsakogiannis D, Papacharalampous M, Toska E, Kyriakopoulou Z, Dimitriou TG, Ruether IG, Komiotis D, Markoulatos P.

Mol Cell Probes. 2015 Feb;29(1):13-8. doi: 10.1016/j.mcp.2014.09.003. Epub 2014 Oct 2.

PMID:
25281890
30.

WT1 interacts with MAD2 and regulates mitotic checkpoint function.

Shandilya J, Toska E, Richard DJ, Medler KF, Roberts SG.

Nat Commun. 2014 Sep 18;5:4903. doi: 10.1038/ncomms5903.

31.

Transcriptomic studies on liver toxicity of acetaminophen.

Toska E, Zagorsky R, Figler B, Cheng F.

Drug Dev Res. 2014 Sep;75(6):419-23. doi: 10.1002/ddr.21227. Review.

PMID:
25195586
32.

Medical pluralism predicts non-ART use among parents in need of ART: a community survey in KwaZulu-Natal, South Africa.

Pantelic M, Cluver L, Boyes M, Toska E, Kuo C, Moshabela M.

AIDS Behav. 2015 Jan;19(1):137-44. doi: 10.1007/s10461-014-0852-6.

33.

Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment.

Castel P, Toska E, Zumsteg ZS, Carmona FJ, Elkabets M, Bosch A, Scaltriti M.

Mol Cell Oncol. 2014 Oct 29;1(3):e963447. doi: 10.4161/23723548.2014.963447. eCollection 2014 Jul-Sep. Review.

34.

Mechanisms of transcriptional regulation by WT1 (Wilms' tumour 1).

Toska E, Roberts SG.

Biochem J. 2014 Jul 1;461(1):15-32. doi: 10.1042/BJ20131587. Review.

PMID:
24927120
35.

WT1 regulates the development of the posterior taste field.

Gao Y, Toska E, Denmon D, Roberts SG, Medler KF.

Development. 2014 Jun;141(11):2271-8. doi: 10.1242/dev.105676. Epub 2014 May 6.

36.

Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation.

Busch M, Schwindt H, Brandt A, Beier M, Görldt N, Romaniuk P, Toska E, Roberts S, Royer HD, Royer-Pokora B.

Hum Mol Genet. 2014 Aug 1;23(15):3958-74. doi: 10.1093/hmg/ddu111. Epub 2014 Mar 11.

37.

Promoting a combination approach to paediatric HIV psychosocial support.

Amzel A, Toska E, Lovich R, Widyono M, Patel T, Foti C, Dziuban EJ, Phelps BR, Sugandhi N, Mark D, Altschuler J; Child Survival Working Group of the Interagency Task Team on the Prevention and Treatment of HIV-infection in Pregnant Women, Mothers and Children.

AIDS. 2013 Nov;27 Suppl 2:S147-57. doi: 10.1097/QAD.0000000000000098. Review.

38.

Prohibitin is required for transcriptional repression by the WT1-BASP1 complex.

Toska E, Shandilya J, Goodfellow SJ, Medler KF, Roberts SG.

Oncogene. 2014 Oct 23;33(43):5100-8. doi: 10.1038/onc.2013.447. Epub 2013 Oct 28.

39.

Presenilin influences glycogen synthase kinase-3 β (GSK-3β) for kinesin-1 and dynein function during axonal transport.

Dolma K, Iacobucci GJ, Hong Zheng K, Shandilya J, Toska E, White JA 2nd, Spina E, Gunawardena S.

Hum Mol Genet. 2014 Mar 1;23(5):1121-33. doi: 10.1093/hmg/ddt505. Epub 2013 Oct 8.

PMID:
24105467
40.

Repression of transcription by WT1-BASP1 requires the myristoylation of BASP1 and the PIP2-dependent recruitment of histone deacetylase.

Toska E, Campbell HA, Shandilya J, Goodfellow SJ, Shore P, Medler KF, Roberts SG.

Cell Rep. 2012 Sep 27;2(3):462-9. doi: 10.1016/j.celrep.2012.08.005. Epub 2012 Aug 30.

41.

An innovative combined antero-retrograde approach for the resolution of the complete iatrogenic obliteration of ureteral ostium: a case report.

Masciovecchio S, Galatioto GP, Saldutto P, Del Rosso A, Di Pierro ED, Toska E, Galica V, Vicentini C.

Arch Ital Urol Androl. 2012 Mar;84(1):39-41.

PMID:
22649960
42.

WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line.

Goodfellow SJ, Rebello MR, Toska E, Zeef LA, Rudd SG, Medler KF, Roberts SG.

Biochem J. 2011 Apr 1;435(1):113-25. doi: 10.1042/BJ20101734.

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