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Items: 1 to 50 of 157

1.

An anthraquinone-enzyme-peptide hybrid as a photo-switchable enzyme.

Sotokawa S, Kitamura T, Takahashi D, Toshima K.

Chem Commun (Camb). 2018 Sep 18;54(75):10614-10617. doi: 10.1039/c8cc06130k.

PMID:
30175837
2.

Stereospecific β-l-Rhamnopyranosylation through an SN i-Type Mechanism by Using Organoboron Reagents.

Nishi N, Sueoka K, Iijima K, Sawa R, Takahashi D, Toshima K.

Angew Chem Int Ed Engl. 2018 Aug 11. doi: 10.1002/anie.201808045. [Epub ahead of print]

PMID:
30098095
3.

Novel hemagglutinin-binding sulfated oligofucosides and their effect on influenza virus infection.

Kosono S, Kasai A, Komaba S, Matsubara T, Sato T, Takahashi D, Toshima K.

Chem Commun (Camb). 2018 Jul 11;54(54):7467-7470. doi: 10.1039/c8cc03865a. Epub 2018 Jun 19.

PMID:
29915822
4.

Systematic and Stereoselective Total Synthesis of Mannosylerythritol Lipids and Evaluation of Their Antibacterial Activity.

Nashida J, Nishi N, Takahashi Y, Hayashi C, Igarashi M, Takahashi D, Toshima K.

J Org Chem. 2018 Jul 6;83(13):7281-7289. doi: 10.1021/acs.joc.8b00032. Epub 2018 Mar 13.

PMID:
29498851
5.

Boronic-Acid-Catalyzed Regioselective and 1,2- cis-Stereoselective Glycosylation of Unprotected Sugar Acceptors via SNi-Type Mechanism.

Tanaka M, Nakagawa A, Nishi N, Iijima K, Sawa R, Takahashi D, Toshima K.

J Am Chem Soc. 2018 Mar 14;140(10):3644-3651. doi: 10.1021/jacs.7b12108. Epub 2018 Feb 26.

PMID:
29457892
6.

Novel 1,2-cis-stereoselective glycosylations utilizing organoboron reagents and their application to natural products and complex oligosaccharide synthesis.

Takahashi D, Tanaka M, Nishi N, Toshima K.

Carbohydr Res. 2017 Nov 27;452:64-77. doi: 10.1016/j.carres.2017.10.004. Epub 2017 Oct 12.

PMID:
29080430
7.

Target-Selective Fluorescence Imaging and Photocytotoxicity against H2 O2 High-Expressing Cancer Cells Using a Photoactivatable Theranostic Agent.

Takagi R, Takeda A, Takahashi D, Toshima K.

Chem Asian J. 2017 Oct 18;12(20):2656-2659. doi: 10.1002/asia.201701004. Epub 2017 Sep 21.

PMID:
28834271
8.

Regio- and stereoselective β-mannosylation using a boronic acid catalyst and its application in the synthesis of a tetrasaccharide repeating unit of lipopolysaccharide derived from E. coli O75.

Nishi N, Nashida J, Kaji E, Takahashi D, Toshima K.

Chem Commun (Camb). 2017 Mar 9;53(21):3018-3021. doi: 10.1039/c7cc00269f.

PMID:
28239730
9.

Total Synthesis of Aquayamycin.

Kusumi S, Nakayama H, Kobayashi T, Kuriki H, Matsumoto Y, Takahashi D, Toshima K.

Chemistry. 2016 Dec 23;22(52):18733-18736. doi: 10.1002/chem.201604697. Epub 2016 Nov 18.

PMID:
27859867
10.
11.

Stereocontrolled Photoinduced Glycosylation Using an Aryl Thiourea as an Organo photoacid.

Kimura T, Eto T, Takahashi D, Toshima K.

Org Lett. 2016 Jul 1;18(13):3190-3. doi: 10.1021/acs.orglett.6b01404. Epub 2016 Jun 23.

PMID:
27337411
12.

Glycosyl-Acceptor-Derived Borinic Ester-Promoted Direct and β-Stereoselective Mannosylation with a 1,2-Anhydromannose Donor.

Tanaka M, Nashida J, Takahashi D, Toshima K.

Org Lett. 2016 May 6;18(9):2288-91. doi: 10.1021/acs.orglett.6b00926. Epub 2016 Apr 19.

PMID:
27093366
13.

Target-selective photo-degradation of AFP-L3 and selective photo-cytotoxicity against HuH-7 hepatocarcinoma cells using an anthraquinone-PhoSL hybrid.

Okuyama M, Ueno H, Kobayashi Y, Kawagishi H, Takahashi D, Toshima K.

Chem Commun (Camb). 2016 Feb 4;52(10):2169-72. doi: 10.1039/c5cc09542e.

PMID:
26698630
14.

Glycosylations of Glycals using N-Iodosuccinimide (NIS) and Phosphorus Compounds for Syntheses of 2-Iodo- and 2-Deoxyglycosides.

Kimura T, Takahashi D, Toshima K.

J Org Chem. 2015 Oct 2;80(19):9552-62. doi: 10.1021/acs.joc.5b01542.

PMID:
26375399
15.

Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells.

Kasai A, Arafuka S, Koshiba N, Takahashi D, Toshima K.

Org Biomol Chem. 2015 Nov 14;13(42):10556-68. doi: 10.1039/c5ob01634g. Epub 2015 Sep 4.

PMID:
26340595
16.

Effects of X‑ray irradiation in combination with ascorbic acid on tumor control.

Hosokawa Y, Monzen S, Yoshino H, Terashima S, Nakano M, Toshima K, Saga R, Kashiwakura I.

Mol Med Rep. 2015 Oct;12(4):5449-54. doi: 10.3892/mmr.2015.4108. Epub 2015 Jul 22.

PMID:
26238154
17.

Regioselective and 1,2-cis-α-Stereoselective Glycosylation Utilizing Glycosyl-Acceptor-Derived Boronic Ester Catalyst.

Nakagawa A, Tanaka M, Hanamura S, Takahashi D, Toshima K.

Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10935-9. doi: 10.1002/anie.201504182. Epub 2015 Jul 23.

PMID:
26205146
18.

Chemical approach for target-selective degradation of oligosaccharides using photoactivatable organic molecules.

Toshima K, Takahashi D.

Glycoconj J. 2015 Oct;32(7):475-82. doi: 10.1007/s10719-015-9591-9. Epub 2015 Apr 28. Review.

PMID:
25913725
19.

Hierarchical CaCO3 chromatography: a stationary phase based on biominerals.

Sato K, Oaki Y, Takahashi D, Toshima K, Imai H.

Chemistry. 2015 Mar 23;21(13):5034-40. doi: 10.1002/chem.201405724. Epub 2015 Feb 9.

PMID:
25677568
20.

A solid-phase affinity labeling method for target-selective isolation and modification of proteins.

Kuwahara D, Hasumi T, Kaneko H, Unno M, Takahashi D, Toshima K.

Chem Commun (Camb). 2014 Dec 21;50(98):15601-4. doi: 10.1039/c4cc06783e. Epub 2014 Oct 31.

PMID:
25360454
21.

Chemical and biological evaluation of unusual sugars, α-aculosides, as novel Michael acceptors.

Ikeda H, Kaneko E, Okuzawa S, Takahashi D, Toshima K.

Org Biomol Chem. 2014 Nov 28;12(44):8832-5. doi: 10.1039/c4ob01877j.

PMID:
25294088
22.

Photo-induced glycosylation using reusable organophotoacids.

Iwata R, Uda K, Takahashi D, Toshima K.

Chem Commun (Camb). 2014 Sep 21;50(73):10695-8. doi: 10.1039/c4cc04753b. Epub 2014 Jul 31.

PMID:
25079918
23.

Photodegradation of amyloid β and reduction of its cytotoxicity to PC12 cells using porphyrin derivatives.

Hirabayashi A, Shindo Y, Oka K, Takahashi D, Toshima K.

Chem Commun (Camb). 2014 Aug 28;50(67):9543-6. doi: 10.1039/c4cc03791j.

PMID:
25012260
24.

Systematic synthesis of sulfated oligofucosides and their effect on breast cancer MCF-7 cells.

Arafuka S, Koshiba N, Takahashi D, Toshima K.

Chem Commun (Camb). 2014 Sep 7;50(69):9831-4. doi: 10.1039/c4cc03544e.

PMID:
24946717
25.

Radiation dose rates now and in the future for residents neighboring restricted areas of the Fukushima Daiichi Nuclear Power Plant.

Harada KH, Niisoe T, Imanaka M, Takahashi T, Amako K, Fujii Y, Kanameishi M, Ohse K, Nakai Y, Nishikawa T, Saito Y, Sakamoto H, Ueyama K, Hisaki K, Ohara E, Inoue T, Yamamoto K, Matsuoka Y, Ohata H, Toshima K, Okada A, Sato H, Kuwamori T, Tani H, Suzuki R, Kashikura M, Nezu M, Miyachi Y, Arai F, Kuwamori M, Harada S, Ohmori A, Ishikawa H, Koizumi A.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E914-23. doi: 10.1073/pnas.1315684111. Epub 2014 Feb 24.

26.

Chiral Brønsted acid mediated glycosylation with recognition of alcohol chirality.

Kimura T, Sekine M, Takahashi D, Toshima K.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12131-4. doi: 10.1002/anie.201304830. Epub 2013 Sep 23. No abstract available.

PMID:
24115608
27.

Design, synthesis and evaluation of a boronic acid based artificial receptor for (L)-DOPA in aqueous media.

Ueno H, Iwata T, Koshiba N, Takahashi D, Toshima K.

Chem Commun (Camb). 2013 Nov 14;49(88):10403-5. doi: 10.1039/c3cc45275a.

PMID:
24079006
28.

Total synthesis of vineomycin B2.

Kusumi S, Tomono S, Okuzawa S, Kaneko E, Ueda T, Sasaki K, Takahashi D, Toshima K.

J Am Chem Soc. 2013 Oct 23;135(42):15909-12. doi: 10.1021/ja407827n. Epub 2013 Oct 11.

PMID:
24074200
29.

Light-induced O-glycosylation of unprotected deoxythioglycosyl donors.

Nakanishi M, Takahashi D, Toshima K.

Org Biomol Chem. 2013 Aug 21;11(31):5079-82. doi: 10.1039/c3ob41143e. Epub 2013 Jul 4.

PMID:
23824170
30.

Target-selective photo-degradation of verotoxin-1 and reduction of its cytotoxicity to Vero cells using porphyrin-globotriose hybrids.

Okochi A, Tanimoto S, Takahashi D, Toshima K.

Chem Commun (Camb). 2013 Jul 11;49(54):6027-9. doi: 10.1039/c3cc42957a.

PMID:
23722161
31.

Improved total synthesis of incednam.

Takada A, Uda K, Ohtani T, Tsukamoto S, Takahashi D, Toshima K.

J Antibiot (Tokyo). 2013 Mar;66(3):155-9. doi: 10.1038/ja.2013.4. Epub 2013 Feb 6.

PMID:
23385133
32.

Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids.

Aoki Y, Tanimoto S, Takahashi D, Toshima K.

Chem Commun (Camb). 2013 Feb 11;49(12):1169-71. doi: 10.1039/c2cc38742e. Epub 2013 Jan 3.

PMID:
23282898
33.
34.

Carbohydrate recognition and photodegradation by an anthracene-Kemp's acid hybrid.

Nishibu M, Takahashi D, Toshima K.

Org Biomol Chem. 2012 Nov 14;10(42):8393-5. doi: 10.1039/c2ob26417j. Epub 2012 Oct 2.

PMID:
23026910
35.

Chemical methods for degradation of target proteins using designed light-activatable organic molecules.

Tanimoto S, Takahashi D, Toshima K.

Chem Commun (Camb). 2012 Aug 11;48(62):7659-71. doi: 10.1039/c2cc30831b. Epub 2012 Jun 27.

PMID:
22739361
36.

Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone-boronic acid hybrids.

Takahashi D, Miura T, Toshima K.

Chem Commun (Camb). 2012 Aug 7;48(61):7595-7. doi: 10.1039/c2cc33559j. Epub 2012 Jun 26.

PMID:
22733145
37.

Target-selective photodegradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by designed fullerene-sugar hybrids.

Tanimoto S, Sakai S, Kudo E, Okada S, Matsumura S, Takahashi D, Toshima K.

Chem Asian J. 2012 May;7(5):911-4. doi: 10.1002/asia.201101043. Epub 2012 Feb 29. No abstract available.

PMID:
22378594
38.

Chemical methods for degradation of target oligosaccharides using designed light-activatable organic molecules.

Takahashi D, Toshima K.

Chem Commun (Camb). 2012 May 11;48(37):4397-407. doi: 10.1039/c2cc17384k. Epub 2012 Mar 1. Review.

PMID:
22378294
39.

A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae].

Hiragaki S, Kobayashi T, Ochiai N, Toshima K, Dekeyser MA, Matsuda K, Takeda M.

Neurotoxicology. 2012 Jun;33(3):307-13. doi: 10.1016/j.neuro.2012.01.016. Epub 2012 Feb 6.

PMID:
22330756
40.

A multicenter study to clarify the optimal HCV-RNA negative period during combined therapy with pegylated interferon plus ribavirin in patients with chronic hepatitis caused by HCV genotype 2.

Nagoshi S, Koshima Y, Nakamura I, Funyu J, Sekine C, Harada Y, Nishikawa K, Yoshida T, Matsui A, Sotome N, Toshima K, Takegoshi S, Shiomi M, Tanaka M, Saito A, Fujiwara K, Mochida S.

Intern Med. 2012;51(1):9-15. Epub 2012 Jan 1.

41.

Efficient and stereoselective synthesis of the disaccharide fragment of incednine.

Ohtani T, Sakai S, Takada A, Takahashi D, Toshima K.

Org Lett. 2011 Nov 18;13(22):6126-9. doi: 10.1021/ol202639v. Epub 2011 Oct 25.

PMID:
22026827
42.

Degradation of target oligosaccharides by anthraquinone-lectin hybrids with light switching.

Imai Y, Hirono S, Matsuba H, Suzuki T, Kobayashi Y, Kawagishi H, Takahashi D, Toshima K.

Chem Asian J. 2012 Jan 2;7(1):97-104. doi: 10.1002/asia.201100586. Epub 2011 Oct 13.

PMID:
21997955
43.

Target-selective photodegradation of oligosaccharides by a fullerene-boronic acid hybrid upon visible light irradiation.

Takahashi D, Hirono S, Toshima K.

Chem Commun (Camb). 2011 Nov 14;47(42):11712-4. doi: 10.1039/c1cc15646b. Epub 2011 Sep 27.

PMID:
21952514
44.

Molecular design, chemical synthesis, and biological evaluation of agents that selectively photo-degrade the transcription factor estrogen receptor-α.

Tsumura K, Suzuki A, Tsuzuki T, Tanimoto S, Kaneko H, Matsumura S, Imoto M, Umezawa K, Takahashi D, Toshima K.

Org Biomol Chem. 2011 Sep 21;9(18):6357-66. doi: 10.1039/c1ob05629h. Epub 2011 Jul 25.

PMID:
21789304
45.

Inhibition of amyloid β aggregation and cytotoxicity by photodegradation using a designed fullerene derivative.

Ishida Y, Fujii T, Oka K, Takahashi D, Toshima K.

Chem Asian J. 2011 Sep 5;6(9):2312-5. doi: 10.1002/asia.201100421. Epub 2011 Jul 20. No abstract available.

PMID:
21780295
46.

[The trial of the domiciliary nutrition support team in which a home medical care office offers].

Yamashita H, Kamei M, Yamada A, Toshima K, Morita H, Kodama N, Okabayashi K.

Gan To Kagaku Ryoho. 2010 Dec;37 Suppl 2:275-7. Japanese.

PMID:
21368548
47.

Photodegradation of target oligosaccharides by light-activated small molecules.

Takahashi D, Hirono S, Hayashi C, Igarashi M, Nishimura Y, Toshima K.

Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10096-100. doi: 10.1002/anie.201005161. No abstract available.

PMID:
21110364
48.

Total synthesis of incednam, the aglycon of incednine.

Ohtani T, Tsukamoto S, Kanda H, Misawa K, Urakawa Y, Fujimaki T, Imoto M, Takahashi Y, Takahashi D, Toshima K.

Org Lett. 2010 Nov 5;12(21):5068-71. doi: 10.1021/ol102400c.

PMID:
20939604
49.

Effective and chemoselective glycosylations using 2,3-unsaturated sugars.

Kusumi S, Sasaki K, Wang S, Watanabe T, Takahashi D, Toshima K.

Org Biomol Chem. 2010 Jul 21;8(14):3164-78. doi: 10.1039/c004204h. Epub 2010 May 26.

PMID:
20505871
50.

Chemoselective glycosylations using 2,3-unsaturated-4-keto glycosyl donors.

Kusumi S, Wang S, Watanabe T, Sasaki K, Takahashi D, Toshima K.

Org Biomol Chem. 2010 Mar 7;8(5):988-90. doi: 10.1039/b925587g. Epub 2010 Jan 7.

PMID:
20165785

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